Black tea consumption and risk of stroke in women and men

Experimental studies have suggested that tea consumption could lower the risk of dyslipidaemia. However, epidemiological evidence is limited, especially in southern China, where oolong tea is the most widely consumed beverage. We conducted a population-based case–control study to evaluate the association between consumption of tea, especially oolong tea, and risk of dyslipidaemia in Shantou, southern China, from 2010 to 2011. Information on tea consumption, lifestyle characteristics and food consumption frequency of 1651 patients with newly diagnosed dyslipidaemia and 1390 controls was obtained using a semi-quantitative questionnaire. Anthropometric variables and serum biochemical indices were determined. Drinking more than 600 ml (2 paos) of green, oolong or black tea daily was found to be associated with the lowest odds of dyslipidaemia risk (P< 0·001) when compared with non-consumption, but only oolong tea consumption was found to be associated with low HDL-cholesterol levels. A dose–response relationship between duration of tea consumption and risk of dyslipidaemia (OR 0·10, 95 % CI 0·06, 0·16), as well as that between amount of dried tea leaves brewed and risk of dyslipidaemia (OR 0·34, 95 % CI 0·24, 0·48), was found. Moreover, consumption of oolong tea for the longest duration was found to be associated with 3·22, 11·99 and 6·69 % lower blood total cholesterol, TAG and LDL-cholesterol levels, respectively. In conclusion, the present study indicates that long-term oolong tea consumption may be associated with a lower risk of dyslipidaemia in the population of Shantou in southern China.

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Coffee, Black Tea, and Green Tea Consumption in Relation to Plasma Metabolites in an Asian Population

Molecular Nutrition & Food Research ◽

10.1002/mnfr.202000527 ◽

2020 ◽

Vol 64 (24) ◽

pp. 2000527 ◽

Cited By ~ 1

Author(s):

Wei Jie Seow ◽

Dorrain Yanwen Low ◽

Wen‐Chi Pan ◽

Samuel H. Gunther ◽

Xueling Sim ◽

...

Keyword(s):

Green Tea ◽

Asian Population ◽

Black Tea ◽

Plasma Metabolites ◽

Tea Consumption

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Mechanisms Underlying the Anti-Depressive Effects of Regular Tea Consumption

Nutrients ◽

10.3390/nu11061361 ◽

2019 ◽

Vol 11 (6) ◽

pp. 1361 ◽

Cited By ~ 12

Author(s):

Dylan O’Neill Rothenberg ◽

Lingyun Zhang

Keyword(s):

Antidepressant Activity ◽

Black Tea ◽

Tea Consumption ◽

Major Pathway ◽

Depression Risk ◽

Microbiome Diversity ◽

Antidepressant Effects ◽

Bdnf Signaling ◽

Risk Ratios

This article is a comprehensive review of the literature pertaining to the antidepressant effects and mechanisms of regular tea consumption. Meta-data supplemented with recent observational studies were first analyzed to assess the association between tea consumption and depression risk. The literature reported risk ratios (RR) were 0.69 with 95% confidence intervals of 0.62–0.77. Next, we thoroughly reviewed human trials, mouse models, and in vitro experiments to determine the predominant mechanisms underlying the observed linear relationship between tea consumption and reduced risk of depression. Current theories on the neurobiology of depression were utilized to map tea-mediated mechanisms of antidepressant activity onto an integrated framework of depression pathology. The major nodes within the network framework of depression included hypothalamic-pituitary-adrenal (HPA) axis hyperactivity, inflammation, weakened monoaminergic systems, reduced neurogenesis/neuroplasticity, and poor microbiome diversity affecting the gut–brain axis. We detailed how each node has subsystems within them, including signaling pathways, specific target proteins, or transporters that interface with compounds in tea, mediating their antidepressant effects. A major pathway was found to be the ERK/CREB/BDNF signaling pathway, up-regulated by a number of compounds in tea including teasaponin, L-theanine, EGCG and combinations of tea catechins and their metabolites. Black tea theaflavins and EGCG are potent anti-inflammatory agents via down-regulation of NF-κB signaling. Multiple compounds in tea are effective modulators of dopaminergic activity and the gut–brain axis. Taken together, our findings show that constituents found in all major tea types, predominantly L-theanine, polyphenols and polyphenol metabolites, are capable of functioning through multiple pathways simultaneously to collectively reduce the risk of depression.

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Daily tea drinking is not associated with newly diagnosed non-alcoholic fatty liver disease in Chinese adults: the Tianjin chronic low-grade systemic inflammation and health cohort study

Nutrition Journal ◽

10.1186/s12937-019-0502-y ◽

2019 ◽

Vol 18 (1) ◽

Cited By ~ 1

Author(s):

Yang Xia ◽

Xuena Wang ◽

Shunmin Zhang ◽

Qing Zhang ◽

Li Liu ◽

...

Keyword(s):

Black Tea ◽

Cross Sectional Study ◽

Low Grade ◽

Tea Consumption ◽

Newly Diagnosed ◽

Chinese Adults ◽

Cross Sectional ◽

Alcoholic Fatty Liver ◽

Tea Drinking ◽

Health Cohort Study

Abstract Background Previous studies have reported that tea extract supplementation has potential benefits on the risk factors of non-alcoholic fatty liver disease (NAFLD); however, no study has investigated the direct effect of daily tea consumption on the prevalence of NAFLD in the general population. This cross-sectional study aimed to evaluate the associations between tea consumption and the prevalence of newly diagnosed NAFLD among Chinese adults. Methods The present cross-sectional study was based on the Tianjin Chronic Low-grade Systemic Inflammation and Health Cohort Study. In total, 19,350 participants were enrolled in the analyses. Tea consumption was assessed via a self-administered food frequency questionnaire. NAFLD was diagnosed via liver ultrasonography and no history of heavy alcohol intake. Logistic regression analysis was used to estimate the associations between tea consumption and the prevalence of NAFLD. Results Consumption of green tea, oolong tea, and black tea were positively associated with the prevalence of newly diagnosed NAFLD before adjustments. Compared with the participants who never drink tea, the odds ratios (95% confidence interval) of newly diagnosed NAFLD in the highest categories (≥ 1 cup/day) of green tea, oolong tea, black tea, and jasmine tea were 1.48 (1.33, 1.65), 1.50 (1.33, 1.68), and 1.28 (1.13, 1.46), and 1.36 (1.20, 1.54) before adjustments, respectively. However, no significant association was found between tea consumption and the prevalence of NAFLD after adjusting for socio-demographic, behavioural, anthropometric, dietary, and clinical confounding factors. Conclusion There is no significant association between daily tea drinking and newly-diagnosed NAFLD in general Chinese adults.

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Effect of adding milk to black tea on vascular function in healthy men and women: a randomised controlled crossover trial

Food & Function ◽

10.1039/c8fo01019f ◽

2018 ◽

Vol 9 (12) ◽

pp. 6307-6314 ◽

Cited By ~ 7

Author(s):

Adilah F. Ahmad ◽

Lisa Rich ◽

Henrietta Koch ◽

Kevin D. Croft ◽

Mario G. Ferruzzi ◽

...

Keyword(s):

Blood Pressure ◽

Vascular Function ◽

Crossover Trial ◽

Black Tea ◽

Tea Consumption ◽

Short Term ◽

Men And Women ◽

Healthy Men ◽

Randomised Controlled ◽

P Addition

Addition of milk to black tea alters the acute/short-term benefical effect of regular black tea consumption on vascular function and blood pressure.

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The Association between Green and Black Tea Consumption on Successful Aging: A Combined Analysis of the ATTICA and MEDiterranean ISlands (MEDIS) Epidemiological Studies

Molecules ◽

10.3390/molecules24101862 ◽

2019 ◽

Vol 24 (10) ◽

pp. 1862 ◽

Cited By ~ 7

Author(s):

Nenad Naumovski ◽

Alexandra Foscolou ◽

Nathan M. D’Cunha ◽

Stefanos Tyrovolas ◽

Christina Chrysohoou ◽

...

Keyword(s):

Green Tea ◽

Successful Aging ◽

Coffee Consumption ◽

Black Tea ◽

Epidemiological Studies ◽

Tea Consumption ◽

Successful Ageing ◽

Mediterranean Islands ◽

Combined Analysis ◽

Green And Black Tea

Tea is one of the most-widely consumed beverages in the world with a number of different beneficial health effects, mainly ascribed to the polyphenolic content of the tea catechins. The aim of this study was to examine the consumption of green, black, or no tea, in relation to the previously validated successful ageing index (SAI; higher values “healthier” ageing) in a combined analysis of adults aged >50 years old from the ATTICA (n = 1128 adults from Athens, Greece metropolitan area) and the MEDiterranean Islands Study (MEDIS) (n = 2221 adults from various Greek island and Mani) studies. After adjusting for age, sex, smoking, and coffee consumption, green tea was positively associated with SAI (b ± SE: 0.225 ± 0.055, p < 0.001), while black tea was negatively associated with SAI (unstandardized b coefficient ± Standard error: −0.807 ± 0.054, p < 0.001). Green tea (vs black tea) consumption, had higher odds of a SAI of over 3.58 out of 10 (OR: 1.77, 95% CI: 1.38–2.28). Green tea consumption was also associated with higher levels of physical activity (p < 0.001) and reduced likelihood of hypertension (p = 0.006) compared with black tea. Two possible mechanisms are that green tea possesses high levels of catechins such as (−)-epigallocatechin 3-gallate and l-theanine compared with black tea. Therefore, the present analysis supports both the role of green tea constituents in successful ageing, as well as its role as an important component of an overall healthy diet in adults aged 50 years and over from these two epidemiological studies.

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Tea Flavonoids and Risk of Cardiovascular and All-Cause Mortality: A Systematic Review and Meta-Analysis

Proceedings of The Nutrition Society ◽

10.1017/s0029665120001573 ◽

2020 ◽

Vol 79 (OCE2) ◽

Cited By ~ 1

Author(s):

Ding Ding Wang ◽

Aedin Cassidy ◽

Mario G. Ferruzzi ◽

Paul Jacques ◽

Elizabeth Johnson ◽

...

Keyword(s):

Systematic Review ◽

Cohort Studies ◽

Green Tea ◽

Lower Risk ◽

Meta Analysis ◽

Black Tea ◽

Tea Consumption ◽

Prospective Cohort Studies ◽

All Cause Mortality ◽

Meta Regression

AbstractThere is increasing evidence that both black and green tea are beneficial for prevention of cardiovascular disease (CVD). We conducted a systematic review and meta-analysis evaluating the effects of tea flavonoids on cardiovascular (CVD) and all-cause mortality outcomes.Searches across five databases including PubMed and Embase were conducted through November 2018 to identify randomized controlled trials (RCTs) and prospective cohort studies reporting cardiovascular and all-cause mortality outcomes. Two investigators independently conducted abstract and full-text screenings, data extractions, and risk of bias (ROB) assessments using the Nutrition Evidence Library Bias Assessment Tool (NEL BAT). Mixed-effects dose-response meta-regression and standard random-effects meta-analyses for outcomes with ≥ 4 studies were performed. 0 RCTs and 38 prospective cohort studies were included in the systematic review. NEL BAT scores ranged from 0–15 (0 being the lowest risk). Our linear meta-regression model showed that each cup increase in daily tea consumption (about 280 mg and 338 mg of total flavonoids for black and green tea, respectively) was associated with 3–4% lower risk of CVD mortality (predicted adjusted RR = 0.96; CI 0.93–0.99 for green tea and RR = 0.97; CI 0.94–0.99 for black tea). Furthermore, eachcup increase in daily tea consumption was associated a 2% lower risk of all-cause mortality (predicted adjusted relative risk (RR) = 0.98; 95% CI 0.97–0.99 for black tea and RR = 0.98; CI 0.96–0.99 for green tea, respectively). Two studies reported multivariable Cox regression analysis results for the relationship between black tea intake and risks of all-cause mortality outcomes. The results from these two studies were combined with our linear meta-regression result in a random-effects model meta-analysis and showed that each cup increase in daily black tea consumption was associated with an average of 3% lower risk of all-cause mortality (pooled adjusted RR = 0.97; 95% CI 0.87- 1.00) with large heterogeneity (I2 = 81.4%; p = 0.005). Current evidence indicates that increased tea consumption may reduce cardiovascular and all-cause mortality in a dose-response manner. This systematic review was registered on PROSPERO.

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