scholarly journals Fluidic-Resistance Control in Arterial Pulsation Simulators

2016 ◽  
Vol 110 (3) ◽  
pp. 171a-172a
Author(s):  
Yuma Shiraishi ◽  
Yun Jung Heo ◽  
Atsushi Sakuma
2016 ◽  
Vol 21 (2) ◽  
pp. 28-37
Author(s):  
Oscar Solís-Salgado ◽  
José Luis López-Payares ◽  
Mauricio Ayala-González

Las vías de drenaje solutos del sistema nervioso central (SNC) participan en el recambio de liquido intersticial con el líquido cefalorraquídeo (LIT-LCR), generando un estado de homeostasis. Las alteraciones dentro de este sistema homeostático afectará la eliminación de solutos del espacio intersticial (EIT) como el péptido βa y proteína tau, los cuales son sustancias neurotóxicas para el SNC. Se han utilizado técnicas experimentales para poder analizar el intercambio LIT-LCR, las cuales revelan que este intercambio tiene una estructura bien organizada. La eliminación de solutos del SNC no tiene una estructura anatómica propiamente, se han descubierto vías de eliminación de solutos a través de marcadores florecentes en el espacio subaracnoideo, cisternas de la base y sistema ventricular que nos permiten observar una serie de vías ampliamente distribuidas en el cerebro. El LCR muestra que tiene una función linfática debido a su recambio con el LIT a lo largo de rutas paravasculares. Estos espacios que rodean la superficie arterial así como los espacios de Virchow-Robin y el pie astrocitico junto con la AQP-4, facilitan la entrada de LCR para-arterial y el aclaramiento de LIT para-venoso dentro del cerebro. El flujo y dirección que toma el LCR por estas estructuras, es conducido por la pulsación arterial. Esta función será la que finalmente llevara a la eliminación de estas sustancias neurotóxicas. En base a la dependencia de este flujo para la eliminación de sustancias se propone que el sistema sea llamado “ la Vía Glinfática”. La bibliografía así como las limitaciones que se encuentran en esta revisión están dadas por la metodología de búsqueda que ha sido realizada principalmente en PubMed utilizando los siguientes términos Mesh: Cerebral Arterial Pulsation, the brain via paravascular, drainage of amyloid-beta, bulk flow of brain interstitial fluid, radiolabeled polyethylene glycols and albumin, amyloid-β, the perivascular astroglial sheath, Brain Glymphatic Transport.


2000 ◽  
Author(s):  
Ralph J. F. Houston ◽  
Jan Menssen ◽  
Marco C. van der Sluijs ◽  
Willy N. Colier ◽  
Berend Oeseburg

1995 ◽  
Vol 113 (1) ◽  
pp. 701-705
Author(s):  
Nelson Wolosker ◽  
Ruben Miguel Ayzin Rosoky ◽  
Baptista Muraco Neto ◽  
Berilo Langer

When a melito-diabetic patient presents trophic infected injury on the limb, it is essential an evaluation of the circulatory conditions for therapeutic procedures orientation. In some circumstances, although arterial pulsation is absent, there is no ischemia of tissues. In these cases, the maintenance treatment, with eventual resection of the necrosed and infected tissues may be adopted. Evolution of 70 diabetic patients with trophic injuries on extremities were submitted to a maintenance treatment. Age of patients varied from 28 to 88 years, with an average of 56.8. The most occurrence was verified in women, with 42 cases. Diabetes non-dependant on insuline (type II) was observed in 64 patients (91.5%), being the remaining 6 patients of type I. Diabetic retinopathy was observed in 14 (20%) of the patients, neuropathy in 22 (31%) and nephropathy in 8 patients (11.4%). All the patients presented arterial pulsation until the popliteal region. They were divided in 2 groups, considering trunk arteries of legs: Group I, pervial legs arteries, composed by 48 patients; Group II, occluded legs arteries, with 22 patients. In what refers to the anatomic local of the injuries, patients were classified in three groups: Group A, formed by 32 patients (45.7%), presenting injuries in one or two toes only, without affecting the metatarsic region; Group B, formed by 16 patients (22.9%), trophic injuries affecting the metatarsic region and Group C, formed by 22 patients (31.4%), injuries affecting the calcaneous region. Injuries in both of the groups were caused by mechanical traumatism. Duration of the injury in the inferior member varied from 7 to 48 days, resulting in a 12 days average. Analyzing pervicacity in trunk arterias and evolution of patients, it may be observed that there has been a significantly better result in those with all the pulses present (81.3% x 45.5%)(p<0,01). Studying the injury locals associated to the evaluation of the cases, we may observe that for injuries in the extreme digital, result is significantly better than in locals more nearly. When distal pulses are absent, there is no significant difference in the result of the treatment, being performed in distal injuries or in the more near ones (p>0,05)(Table IV).


2007 ◽  
Vol 135 (5-6) ◽  
pp. 330-334
Author(s):  
Radoje Colovic ◽  
Marjan Micev ◽  
Vladimir Radak ◽  
Nikica Grubor ◽  
Natasa Colovic ◽  
...  

Gastrointestinal tumors arising from autonomous nerves of Meisner?s or Auerbach?s plexus (plexomas and plexosarcomas) are rare tumors in only 87 cases described in the literature up to 2001. We present a very rare case of gastrointestinal stromal tumor (plexosarcoma) of the third and fourth portion of the duodenum, 130x98x87 mm in diameter, arising from its back wall, with central necrosis of the well circumscribed tumor, which communicated with the duodenum through an ulceration of 15x7mm in diameter, spreading towards the great vessels of the retroperitoneum. It was gradually and carefully removed, together with 17 cm of the duodenum and few centimeters of the jejunum with end-to-end duodenojejunostomy below the Vater?s papilla. During the removal of the tumor, the superior mesenteric artery, being within the tumor?s capsule, was accidentally ligated but not transsected. In spite of the removal of the ligature, the artery became thrombosed due to damage of the intima by ligature so that it had to be resected and reanastomosed. After otherwise uneventful recovery, except for a mild pus discharge through the drain, not far from the arterial anastomosis, the patient suddenly started bleeding on the 13th day after surgery. At emergency reoperation, a rupture of the mesenteric artery above the thrombosed anastomosis was found. In spite of absence of the arterial pulsation within the mesentery, the bowel looked vital and the back flow from the artery was satisfactory. The arterial rereconstruction was not possible, so the artery was ligated. The postoperative recovery was surprisingly uneventful. The patient was discharged ten days after surgery and has stayed symptom-free so far. .


2021 ◽  
Author(s):  
Dmytro Vakulenko ◽  
Liudmyla Vakulenko ◽  
Leonid Hryshchuk ◽  
Lesya Sas

The aim of study is finding complex pathological process markers occurred in COVID-19. Adaptive capacity, cardiovascular features, autonomic, central nervous systems in 67 patients with severe COVID-19 were studied and evaluated using (suggested by authors) temporal, spectral, correlation analysis of arterial oscillograms (AOG). The method is based on mathematical analysis adaptation of electrocardiographic signal heart rate variability to arterial pulsation variability analysis recorded during blood pressure measurement using an electronic tonometer VAT 41–2. Received results were compared with AOG 480 healthy (including 68 people after exercising) and 26 patients in a closed ward at psychoneurological hospital. Study results showed patients with severe COVID-19 have disorders at (four) cardiovascular system (CVS) regulation levels. It’s confirmed by lack of adequate sympathetic-adrenal response to a stressful situation due to severe COVID-19; higher than in healthy, parasympathetic part activity of autonomic nervous system. AOG spectral analysis revealed violation of management centralization, communication and coordination between CVS regulation levels. This leads to functional reserves decrease, low stress resistance of body and finally to a disease severe course and recovery processes. Arterial oscillography can be used to search markers of complex pathological processes occurred in COVID-19 and to improve methods of diagnosis, treatment, control of long-term results in clinical and family medicine.


BioTechniques ◽  
2019 ◽  
Vol 66 (5) ◽  
pp. 235-239
Author(s):  
Mads Frederik Hansen ◽  
Anders Meyer Torp ◽  
Jonas Stenløkke Madsen ◽  
Henriette Lyng Røder ◽  
Mette Burmølle

Micromachines ◽  
2020 ◽  
Vol 11 (3) ◽  
pp. 266 ◽  
Author(s):  
Dalei Jing ◽  
Xuekuan Zhan

The present work theoretically and numerically studies the electroosmotic flow (EOF) within a fractal treelike rectangular microchannel network with uniform channel height. To obtain minimum EOF fluidic resistance, the microchannel cross-sectional dimensions of the fractal network are optimized. It is found that the cross-sectional dimension dependence of EOF fluidic resistance within a symmetric fractal network is only dependent on the channel width when the total channel volume is constant, and the optimal microchannel widths to reach the minimum EOF fluidic resistance satisfy the scaling law of κ = N−1 (where κ is the width ratio of the rectangular channels at two successive branching levels, N is the branching number); however, for the symmetric fractal network with constant total surface area, the optimal cross-sectional dimensions should simultaneously satisfy κ = N−1 and H = S 4 l 0 1 − γ N 1 − ( γ N ) m + 1 (where H is the channel height, S is the total channel surface area, l0 is the channel length at the original branching level, γ is the channel length ratio at two successive branching levels and m is the total branching level) to obtain the minimum EOF fluidic resistance. The optimal scaling laws established in present work can be used for the optimization design of the fractal rectangular microchannel network for EOF to reach maximum transport efficiency.


2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Hengfei Zhang ◽  
Sijin Wu ◽  
Weixian Li ◽  
Yonghong Wang ◽  
Mingli Dong ◽  
...  

Pulse diagnosis is one of the four diagnostic methods of traditional Chinese medicine. However it suffers from the lack of objective and efficient detection method. We propose a noncontact optical method to detect human wrist pulse, aiming at the precise determination of the temporal and spatial distributions of pulse. The method uses the spatial-carrier digital speckle pattern interferometry (DSPI) to measure the micro/nanoscale skin displacement dynamically. Significant improvements in DSPI measurement have been made to allow the DSPI to detect the comprehensive information of the arterial pulsation at locations of Cun, Guan, and Chi. The experimental results prove that the spatiotemporal distributions of pulse can be obtained by the proposed method. The obtained data can be further used to describe most of the pulse parameters such as rate, rhythm, depth, length, width, and contour.


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