scholarly journals Aplication Arterial Oscilography to Study the Adaptive Capacity of Subject with COVID-19 in Primary Care

2021 ◽  
Author(s):  
Dmytro Vakulenko ◽  
Liudmyla Vakulenko ◽  
Leonid Hryshchuk ◽  
Lesya Sas
Keyword(s):  
Adaptive Capacity ◽  
Blood Pressure Measurement ◽  
Pathological Process ◽  
Long Term Results ◽  
Stressful Situation ◽  
Spectral Correlation ◽  
Recovery Processes ◽  
Arterial Pulsation ◽  
Central Nervous Systems ◽  
Communication And Coordination

The aim of study is finding complex pathological process markers occurred in COVID-19. Adaptive capacity, cardiovascular features, autonomic, central nervous systems in 67 patients with severe COVID-19 were studied and evaluated using (suggested by authors) temporal, spectral, correlation analysis of arterial oscillograms (AOG). The method is based on mathematical analysis adaptation of electrocardiographic signal heart rate variability to arterial pulsation variability analysis recorded during blood pressure measurement using an electronic tonometer VAT 41–2. Received results were compared with AOG 480 healthy (including 68 people after exercising) and 26 patients in a closed ward at psychoneurological hospital. Study results showed patients with severe COVID-19 have disorders at (four) cardiovascular system (CVS) regulation levels. It’s confirmed by lack of adequate sympathetic-adrenal response to a stressful situation due to severe COVID-19; higher than in healthy, parasympathetic part activity of autonomic nervous system. AOG spectral analysis revealed violation of management centralization, communication and coordination between CVS regulation levels. This leads to functional reserves decrease, low stress resistance of body and finally to a disease severe course and recovery processes. Arterial oscillography can be used to search markers of complex pathological processes occurred in COVID-19 and to improve methods of diagnosis, treatment, control of long-term results in clinical and family medicine.

scholarly journals EXTRAPLEURAL PNEUMOLYSIS FOR CAVITARY PULMONARY TUBERCULOSIS TREATMENT

2020 ◽  
pp. 15-20
Author(s):  
P. G. Gadzhieva ◽  
D. B. Giller ◽  
A. A. Glotov ◽  
O. Sh. Kesaev ◽  
V. V. Koroev ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Multidrug Resistant ◽  
Pathological Process ◽  
Tuberculosis Treatment ◽  
Long Term Results ◽  
Filling Material ◽  
Different Types ◽  
Positive Effect ◽  
Observation Period

Objective. To increase efficiency of cavitary pulmonary tuberculosis treatment by developing modern indications and technology of extrapleural pneumolysis with filling material.Material and methods. We reviewed 25 patients with cavitary pulmonary tuberculosis and bacterial excretion who had undergone extrapleural pneumolysis with different types of filling material in 2004–2015. In 16 cases, we performed surgery in patients with one lung.Results. 56% of operated patients demonstrated extensively drug-resistant TB, 40% had multidrug-resistant TB. Cavities were closed and bacterial excretion ceased in 92% of patients at discharge. Long-term results with observation period from 1 to 12 years were analyzed in 24 patients, 17 (71%) of them had complete clinical efficacy.Conclusion. Extrapleural pneumolysis is a mini-invasive surgical treatment that can prove positive effect in patients with non-fibrotic changes in a cavity wall and pathological process in upper parts of the lungs. 

Results of locally advanced laryngopharyngeal and cervical part of esophagus cancers treatment

2016 ◽  
Vol 21 (3) ◽  
pp. 156-159
Author(s):  
Andrey N. Rudyk ◽  
E. I Sigal ◽  
M. V Burmistrov
Keyword(s):  
High Frequency ◽  
Locally Advanced ◽  
Survival Rates ◽  
Pathological Process ◽  
Chemoradiation Therapy ◽  
Treatment Choice ◽  
Long Term Results ◽  
Surgical Method ◽  
Methods Of Treatment

Issues of locally advanced cancers which involve into the pathological process laryngopharynx and cervical part of esophagus remain to be actual till the present time. Unsatisfactory long-term results lead to the absence of common approaches and clear guidelines on the methods of the treatment choice (radiotherapy, chemoradiation therapy, surgery). Many researchers suppose that the foremost decision is to include surgical component into the treatment schemes of such patients. Main surgical method of the treatment is laryngopharyngectomy or laryngopharyngoesophagectomy. It depends on the extension of cancer. Different kinds of grafts (gastric, jejunal and colon) are used for esophageal reconstrution. The high frequency of complications after surgery, low survival rates are main motives for the search of effective methods of treatment.

Degenerative Disorders of the Temporomandibular Joint: Etiology, Diagnosis, and Treatment

2008 ◽  
Vol 87 (4) ◽  
pp. 296-307 ◽  
Author(s):  
E. Tanaka ◽  
M.S. Detamore ◽  
L.G. Mercuri
Keyword(s):  
Tissue Engineering ◽  
Temporomandibular Joint ◽  
Adaptive Capacity ◽  
Pathological Process ◽  
Degenerative Changes ◽  
Diagnosis And Treatment ◽  
Factors Associated ◽  
Non Invasive ◽  
Degenerative Disorders ◽  
Inflammatory Changes

Temporomandibular joint (TMJ) disorders have complex and sometimes controversial etiologies. Also, under similar circumstances, one person’s TMJ may appear to deteriorate, while another’s does not. However, once degenerative changes start in the TMJ, this pathology can be crippling, leading to a variety of morphological and functional deformities. Primarily, TMJ disorders have a non-inflammatory origin. The pathological process is characterized by deterioration and abrasion of articular cartilage and local thickening. These changes are accompanied by the superimposition of secondary inflammatory changes. Therefore, appreciating the pathophysiology of the TMJ degenerative disorders is important to an understanding of the etiology, diagnosis, and treatment of internal derangement and osteoarthrosis of the TMJ. The degenerative changes in the TMJ are believed to result from dysfunctional remodeling, due to a decreased host-adaptive capacity of the articulating surfaces and/or functional overloading of the joint that exceeds the normal adaptive capacity. This paper reviews etiologies that involve biomechanical and biochemical factors associated with functional overloading of the joint and the clinical, radiographic, and biochemical findings important in the diagnosis of TMJ-osteoarthrosis. In addition, non-invasive and invasive modalities utilized in TMJ-osteoarthrosis management, and the possibility of tissue engineering, are discussed.

Advanced forms of kidney tuberculosis with fistula formation: modern views

2020 ◽  
pp. 60-69
Author(s):  
Andrey Volkov ◽  
Oleg Zuban ◽  
Galina Saenko
Keyword(s):  
Surgical Treatment ◽  
Pathological Process ◽  
Long Term Results ◽  
Fistula Formation ◽  
Results Of Treatment ◽  
Internal Fistulas ◽  
Intestinal Fistulas ◽  
Kidney Lesions

The aim of the study is to evaluate results of surgical treatment in patients with tuberculous pyonephrosis. In 2004 - 2019 12 patients underwent nephroureterectomy. The disease was complicated by involvement of nearby organs in pathological process and appearance of spontaneous external and internal fistulas in 100% of cases, it manifested with symptoms mostly not associated with kidney lesions. Reno-intestinal fistulas were found intraoperatively in 5 patients. Good long-term results of treatment were achieved mainly due to surgical debridment.

scholarly journals Precision resection of pulmonary tuberculoma using Nd:YAG-laser

2022 ◽  
Vol 99 (12) ◽  
pp. 27-32
Author(s):  
I. A. Dyachkov ◽  
I. Ya. Motus ◽  
A. V. Bazhenov ◽  
S. N. Skornyakov ◽  
R. B. Berdnikov
Keyword(s):  
Nd:Yag Laser ◽  
Pathological Process ◽  
Long Term Results ◽  
Laser Resection ◽  
Group I ◽  
Surgical Methods ◽  
Duration Of Surgery ◽  
The Mean ◽  
Group Ii

The objective of the study: a comparative study of immediate and long-term results of pulmonary tuberculoma precision resection with Nd:YAG-laser with a wavelength of 1,318 nm and atypical resection with suturing devices.Subjects and Methods. Two groups of 58 patients each were compared. The groups were comparable in terms of gender, age, the nature of the concomitant pathology and the main pathological process. In Group I, patients were operated on using precision 1,318-nm Nd:YAG-laser resection, and in Group II, the sublobar resection with suturing devices were used.Results. The mean duration of hospital stay in Groups I and II was 19.10 ± 6.02 and 19.20 ± 6.02 days respectively (p > 0.05), the duration of surgery made 65 [55; 75] and 55 [45; 60] minutes (p > 0.05), the mean volume of surgical blood loss was 50 [33; 70] and 70 [50; 165] ml (p > 0.05), and the mean duration of pleural cavity drainage after surgery was 4 [3; 5] and 4 [3; 6] days (p > 0.05). Statistically significant differences were noted in the mean volume of the resected part of the lung: 14.0 ± 7.4 mm3 in Group I versus 95.0 ± 9.7 mm3 in Group II (p ≤ 0.05). The complete clinical and radiological cure was achieved in 70% of patients in Group I and 82% in Group II. According to MSCT data, in 91.6% of cases, a thin linear scar is formed in the area of precision intervention.Conclusion: The surgical methods are comparable in terms of immediate and long-term results but precision laser resection minimizes the removal of intact tissue during the removal of tuberculomas.

Psoriasis: can a systemic disease become a way of life?

2021 ◽  
pp. 8-13
Author(s):  
Sergey Petrovich Armakov
Keyword(s):  
Western Europe ◽  
High Efficiency ◽  
Skin Diseases ◽  
Systemic Disease ◽  
Pathological Process ◽  
Stressful Situation ◽  
Wide Range ◽  
Severity Of The Disease ◽  
Total Structure ◽  
The Impact

According to the literature, about 3% of the world's population suffers from psoriasis; the highest prevalence is observed in the countries of Western Europe and Scandinavia, while this disease is less common among representatives of the Mongoloid and Negroid races. In different countries, the proportion of psoriasis is from 10 to 40% in the total structure of skin diseases. This pathological process has a multifactorial nature; it is based on hyperproliferation of keratinocytes with impaired differentiation, which clinically manifests itself in the form of damage to the skin, nails and joints. Psoriasis is one of the most common dermatoses; men and women suffer from it equally often. The triggering factor for the development of psoriasis can be a psychoemotional stressful situation, as well as the impact of other environmental factors, including hypothermia, trauma, infections, and taking certain medications. As a result of exposure to provoking endogenous and exogenous factors, autoimmune mechanisms, which are based on increased activity of T cells, are triggered. About 70% of psoriasis patients have mild to moderate severity of the disease. Despite the wide range of drugs used to treat psoriasis, they do not demonstrate high efficiency, and the prevalence of this pathology is growing every year. The existing methods of treatment help to cope with exacerbations and relieve inflammation, however, it is impossible to completely cure this disease, and the risk of relapse always remains. One of the tasks of doctors involved in the treatment of psoriasis is not only to reduce the severity of symptoms, but also to teach a patient suffering from psoriasis to live a full life and not depend to a large extent on the manifestations of the disease and the opinions of others.

scholarly journals Subchondral bone condition and total knee arthroplasty in patients with knee osteoarthritis

2017 ◽  
Vol 20 (1) ◽  
pp. 12-16 ◽  
Author(s):  
Valeriy U. Murylyov ◽  
Galina L. Sorokina ◽  
Ella V. Kurilina ◽  
Leonid R. Ivanenko
Keyword(s):  
Adverse Effects ◽  
Knee Joint ◽  
Subchondral Bone ◽  
Knee Arthroplasty ◽  
Perioperative Period ◽  
Pathological Process ◽  
Long Term Results ◽  
Bone Pathology ◽  
Total Arthroplasty ◽  
Choice Of Treatment

Background: 6% of adults suffer from knee joint osteoarthritis. In some cases, the method of choice of treatment is knee arthroplasty. The etiology of osteoarthritis remains largely unclear, but the question of involving the subchondral bone in the pathological process is beyond doubt. One of the causes of pain and other adverse effects after knee replacement may be subchondral bone pathology of the femur and tibia. Aims: To study the changes in the condyles of the tibia in osteoarthritis and to determine the possible impact of these changes on the development of instability of the knee joint endoprosthesis. Methods: From December 2014 to February 2016, 56 patients were examined. They underwent total arthroplasty of the knee joint. The average age of the patients was 63 years (from 55 to 78 years). Women were 52 (93%), men - 4 (7%). A histological examination of the resected tibial condyles was carried out to reveal bone pathology. Results: Typical changes for osteoarthritis were found microscopically. In all cases the signs of osteoporosis were present. A clear histological picture of osteomalacia in the non-calcinated bone was found in 15 women. Conclusions: Having studied the subchondral bone in these patients we can conclude that the knee endoprosthesis is implanted into a weakened bone, which can lead to adverse effects. To improve the long-term results of surgical treatment, medical correction of bone tissue pathology in the perioperative period is suggested.

Evaluation of two methods of teaching blood pressure measurement

1988 ◽  
Vol 52 (9) ◽  
pp. 519-521
Author(s):  
NK Nordstrom ◽  
S Longenecker ◽  
HL Whitacre ◽  
FM Beck
Keyword(s):  
Blood Pressure ◽  
Pressure Measurement ◽  
Blood Pressure Measurement
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