Women with anxiety disorders during pregnancy are at increased risk of intense postnatal depressive symptoms: a prospective survey of the MATQUID cohort

2004 ◽  
Vol 19 (8) ◽  
pp. 459-463 ◽  
Author(s):  
A.L. Sutter-Dallay ◽  
V. Giaconne-Marcesche ◽  
E. Glatigny-Dallay ◽  
H. Verdoux
Keyword(s):  
Depressive Symptoms ◽  
Pregnant Women ◽  
Postnatal Depression ◽  
Depressive Disorders ◽  
Post Partum ◽  
Depression Scale ◽  
Maternity Hospital ◽  
Pregnancy Anxiety ◽  
Postnatal Depressive Symptoms ◽  
Increased Risk

AbstractObjective– Studies have suggested that women with pregnancy anxiety may be at greater risk of postnatal depression (PND). However, due to the high comorbidity between anxiety and depressive disorders, this finding may be confounded by the association between prenatal depression and postnatal depression. The aim of the present prospective study was to assess whether anxiety disorder (AD) during pregnancy is an independent predictor of intensity of postnatal depressive symptoms.Method.– The MATQUID cohort survey was conducted on pregnant women (n = 497) attending a state maternity hospital. Psychiatric status during pregnancy was assessed during the third trimester using a structured diagnostic interview. Intense postnatal depressive symptoms at 6 weeks post-partum were defined by a score >12 on the Edinburgh Postnatal Depression Scale (EPDS).Results.– Nearly one out of four women (24.1%) presented with at least one pregnancyAD, and 29 (5.8%) presented with a score >12 on the EPDS. After adjustment for presence of major depression during pregnancy and other confounding factors, women with pregnancy AD were nearly three times more likely to present with intense postnatal depressive symptoms (OR = 2.7, 95%CI 1.1-6.3, P = 0.03).Conclusion.– Promoting the recognition and management of AD in pregnant women may be of interest for the prevention of postnatal depression.

The Mental Health Characteristics of Pregnant Women With Depressive Symptoms Identified by the Edinburgh Postnatal Depression Scale

2014 ◽  
Vol 75 (04) ◽  
pp. 393-398 ◽  
Author(s):  
Linda B. Lydsdottir ◽  
Louise M. Howard ◽  
Halldora Olafsdottir ◽  
Marga Thome ◽  
Petur Tyrfingsson ◽  
...  
Keyword(s):  
Mental Health ◽  
Depressive Symptoms ◽  
Pregnant Women ◽  
Postnatal Depression ◽  
Edinburgh Postnatal Depression Scale ◽  
Depression Scale

scholarly journals Associations of Tryptophan, Docosahexaenoic Acid (DHA), and Vitamin D With Sleep Quality and Depression During Pregnancy

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 766-766
Author(s):  
Amber Kautz ◽  
Ying Meng ◽  
Emily S Barrett ◽  
Jessica Brunner ◽  
Richard Miller ◽  
...  
Keyword(s):  
Vitamin D ◽  
Depressive Symptoms ◽  
Docosahexaenoic Acid ◽  
Sleep Quality ◽  
Pregnant Women ◽  
Maternal Mental Health ◽  
Smoking Status ◽  
Depression Scale ◽  
Poor Sleep ◽  
Increased Risk

Abstract Objectives During pregnancy women are at increased risk of poor sleep quality and depression. Serotonin and melatonin are compounds that are involved in regulation of sleep and mood. Several nutrients are involved in the synthesis of these compounds, including tryptophan, docosahexaenoic acid (DHA), and vitamin D. Studies exploring associations between these nutrients and sleep, as well as mood, have been largely limited to the general population, showing mixed results. The aim of this study was to assess the associations of dietary intake of these nutrients with sleep quality and depression in pregnant women. Methods Participants enrolled in the Understanding Pregnancy Signals and Infant Development (UPSIDE) Study (n = 253) were included in this analysis if they completed dietary, sleep and depression assessments during the 2nd trimester. Dietary and supplement intake were measured using 24-hour dietary recalls. The NCI method was used to estimate usual intake. Sleep quality was measured with the Pittsburgh Sleep Quality Index (PSQI). Depressive symptoms were measured with the Edinburgh Postnatal Depression Scale (EPDS). Multivariable linear regression was conducted to estimate the associations between nutrients and sleep/depression, adjusting for age, race/ethnicity, parity, education, early pregnancy body mass index, smoking status, energy and macronutrient intake. Results The NCI adjusted mean intakes of tryptophan, DHA, and vitamin D were 1.02 ± 0.11 g/day, 0.13 ± 0.11g/day, and 19.74 ± 21.80 mcg/day, respectively. Mean PSQI score was 6.15 ± 3.39, where higher scores indicated worse sleep quality, and mean EPDS score was 5.84 ± 4.77, where higher scores indicated increased severity of depressive symptoms. Tryptophan intake was inversely associated with EPDS scores (b = −15.23, 95%CI: −26.75, −3.72). The associations between DHA, vitamin D, and depression were not significant. The selected nutrients were not associated with PSQI scores. Conclusions In this study, higher tryptophan intake was associated with lower depressive symptoms among pregnant women during the second trimester. Additional research on the relationship between tryptophan intake and maternal mental health during pregnancy is warranted. Funding Sources NIH, Mae Stone Goode Foundation, Wynne Family Foundation.

Assessing the utility of the Healthy Start Screen to predict an elevated Edinburgh Postnatal Depression Scale score

2020 ◽  
Vol 48 (5) ◽  
pp. 483-487
Author(s):  
Mikela M. Padilla ◽  
Dikea Roussos-Ross ◽  
Amie J. Goodin
Keyword(s):  
Pregnant Women ◽  
Postnatal Depression ◽  
Edinburgh Postnatal Depression Scale ◽  
Depression Scale ◽  
The State ◽  
Healthy Start ◽  
Behavioral Risk ◽  
Postpartum Visit ◽  
Prenatal Visit ◽  
Increased Risk

AbstractObjectiveTo examine the utility of the Healthy Start Screen (HSS), which is an assessment of health, environment, and behavioral risk factors offered to all pregnant women in the state of Florida, in identifying women at risk for developing postpartum depression (PPD).MethodsThe sample for this Institutional Review Board (IRB)-approved, retrospective study consisted of patients who presented to a women’s clinic for a new prenatal visit. Those patients who completed both the HSS at their prenatal visit and the Edinburgh Postnatal Depression Scale (EPDS) at their postpartum visit were included. We focused on items 1–10 of the HSS, where patients could respond with either “yes” or “no”, and identified a positive EPDS as any score greater than or equal to 12.ResultsWomen who identified as feeling down, depressed or hopeless, feeling alone when facing problems, to having ever received mental health services, or to having any trouble paying bills were more likely to have an EPDS score greater than or equal to 12.ConclusionThe HSS, currently mandated by the state of Florida to be offered to all pregnant women, is a useful tool for identifying women at increased risk of developing PPD.

scholarly journals The Need for Universal Screening for Postnatal Depression in South Africa: Confirmation from a Sub-District in Pretoria, South Africa

2020 ◽  
Vol 17 (19) ◽  
pp. 6980
Author(s):  
Kebogile Mokwena ◽  
Itumeleng Masike
Keyword(s):  
South Africa ◽  
Depressive Symptoms ◽  
Primary Healthcare ◽  
Postnatal Depression ◽  
Depression Scale ◽  
Public Health Problem ◽  
Sub Saharan Africa ◽  
Cross Sectional Survey ◽  
Healthcare Facilities ◽  
Postnatal Depressive Symptoms

Although postnatal depression (PND) is a worldwide public health problem, it is relatively higher in developing countries, including countries in Sub-Saharan Africa. Postnatal depression is not routinely screened for in primary healthcare facilities in South Africa, despite its reported compromise on mother and child health. The purpose of this study was to determine the prevalence of, as well as factors associated with, postnatal depression in a sample of clinic attendees in a sub district in Tshwane, South Africa. A quantitative and cross-sectional survey was conducted in a sample of 406 women in three healthcare facilities. The Edinburgh Postnatal Depression Scale (EPDS) was used to collect data from women who had infants between the ages of 0 and 12 months. The cut-off point for the EPDS for the depressed category was a score of 13 out of a maximum of 30. The majority of the women (57.14%, n = 232) had scores of 13 and above, which is indicative of postnatal depressive symptoms. On logistic regression, postnatal depressive symptoms were significantly associated with lack of support in difficult times (p < 0.001, 95% CI 10.57–546.51), not having the preferred sex of the baby (p = 0.001, 95% CI 0.37–0.58), low household income (p < 0.001, 95% CI 1.23–1.67), and an older baby (p = 0.005, 95% CI 1.21–1.49). The results show the high proportion of women who have postnatal depression but remain undiagnosed and untreated, and therefore confirm the need for routine screening for postnatal depressive symptoms in primary healthcare facilities, which are used by the majority of women in South Africa.

Screening for Postnatal Depression in Routine Primary Care: Properties of the Edinburgh Postnatal Depression Scale in an Australian sample

2005 ◽  
Vol 39 (9) ◽  
pp. 833-839 ◽  
Author(s):  
Jeannette Milgrom ◽  
Jennifer Ericksen ◽  
Lisa Negri ◽  
Alan W. Gemmill
Keyword(s):  
Primary Care ◽  
Postnatal Depression ◽  
Depressive Disorders ◽  
Edinburgh Postnatal Depression Scale ◽  
Screening Program ◽  
Post Partum ◽  
Depression Scale ◽  
Absolute Difference ◽  
Roc Curve Analysis ◽  
Dsm Iv

Objectives: First, to explore the utility of the Edinburgh Postnatal Depression Scale (EPDS) in routine primary care through a large community screening program. Next, to compare administration of a second EPDS versus the Beck Depression Inventory (BDI) in identifying postnatal depression in the prescreened population. Method: Screening with the EPDS through Maternal and Child Health Centres at 4 months post-partum. Women scoring ≥12 were assessed against DSM-IV criteria and completed a BDI and a second EPDS. These data were subjected to receiver operating characteristic (ROC) analyses. Results: Of 4148 screened, 533 (12.8%) scored ≥12. Of these, 344 were assessed against DSM-IV criteria: 193 (56%) – major depressive disorder; 67 (20%) – other diagnoses that incorporated depression. Positive predictive value at screening was therefore 76%. Another 45 (13%) had non-depressive disorders and 39 (11%) were psychiatric non-cases. The BDI was the better diagnostic instrument in the prescreened population, having a significantly higher efficiency as quantified by ROC curve analysis, though the absolute difference in efficiency was small (approximately 6%). Conclusions: Screening with the EPDS integrated well into routine primary care. Twostep screening offers one way of achieving acceptable balances of operational simplicity and diagnostic accuracy.

Post-partum depression risk factors in pregnant women

2016 ◽  
Vol 33 (S1) ◽  
pp. s279-s280
Author(s):  
A. Ugarte ◽  
P. López ◽  
C. Serrulla ◽  
M.T. Zabalza ◽  
J.G. Torregaray ◽  
...  
Keyword(s):  
Risk Factors ◽  
Depressive Symptoms ◽  
Postpartum Depression ◽  
Depressive Disorders ◽  
Post Partum ◽  
Depression Scale ◽  
Personal History ◽  
Assisted Reproductive Technique ◽  
History Of ◽  
Competing Interest

IntroductionPostpartum depression has a prevalence of 15% and has consequences for mother and baby (delayed physical, social and cognitive development). It's essential to prevent the illness with an early identification of Risk Factors (RF).MethodsFive hundred and seventy-two women in 3rd trimester of pregnancy were evaluated and selected those with ≥ 1 RF (n = 290). We re-evaluated in the postpartum with Edinburgh Depression Scale and selected those with subsyndromal depressive symptoms (≥ 7.5) (n = 57). Clinical, demographic and functional data were collected.ResultsA total of 50.7% had RF. A percentage of 48.6 had family history of mental illness (MI), 34.1%had personal history of (MI) and 34.1% had some pregnancy associated illness. Twenty percent had needed some assisted reproductive technique, 14.1% had little family support and 15.2% had little couple support, 3.8% showed anxiety-depressive disorders during pregnancy, 19.7% had depressive symptoms after delivery. The mean age was 33.67. No significant differences between patients with and without RF (T-1858, P 0.064). Among women with RF, 59.6% were married, 35.1% single and 3.0% had other situation. 89.5% live with their own family, 8.8% with their family of origin, 1.8% alone. 50.8% had university studies.ConclusionsAssessing RF during pregnancy can help these women, since we see that the 19.7% will have serious risk of developing postpartum depression. The RF to take more into account are not those related to social-academic development, neither the presence of anxiety-depressive symptoms during pregnancy, but the family or personal history of (MI) and the presence of a pregnancy associated illness. Early detection and treatment may prevent the development of this disease improving the quality of life of mother and babies’ development.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Prevalence and factors associated with male postnatal depression in China

2020 ◽  
Keyword(s):  
Mental Health ◽  
Social Support ◽  
Depressive Symptoms ◽  
Postnatal Depression ◽  
Edinburgh Postnatal Depression Scale ◽  
Depression Scale ◽  
Depression Symptoms ◽  
Spousal Relationship ◽  
Factors Associated ◽  
Postnatal Depressive Symptoms

Background and Objective: Male postnatal depression has recently begun to attract more research attention. However, it often remains unrecognized despite affecting not only the health of the child but also the spousal relationship and family welfare. This study aimed to estimate the prevalence of male postnatal depressive symptoms in Guangzhou, South China. It also explored sociodemographic factors and psychological variables as predictors of postnatal depression symptoms. Materials and methods: Chinese men whose children had been born within the last six months were screened using the Edinburgh Postnatal Depression Scale for depressive symptoms, the Vulnerable Personality Style Questionnaire for personality, and the Social Support Rating Scale for social support. Sociodemographic and psychosocial variables were descriptively analyzed and logistic regression was also employed to analyze the predictive impact of factors associated with depression. Results: A total of 212 new Chinese fathers participated in the study. The prevalence of postnatal depression was 24.1% assessed by the Edinburgh Postnatal Depression Scale cutoff score of 10. Depressive symptoms were found to be significantly associated with employment status and vulnerable personality traits. Higher family income, wanted pregnancy, having a child of the desired gender, more family support and objective support (OR = 0.598, 95% CI = 0.312-0.896) were all protective factors for depressive symptoms among new Chinese fathers. Conclusion: This study indicated that there is a need to routinely screen for postnatal depressive symptoms in men. Early identification and timely referral to healthcare professionals may prevent postnatal depression and improve the mental health of new fathers. It is important for healthcare providers to develop and evaluate information resources in print and online so as to establish how best to identify and manage paternal postnatal mental health needs. This study also suggests that new fathers need to be provided with targeted resources concerning postnatal mental health and informed as to how to access them and who can be approached for professional support.

1035325 Analisis Faktor Penyebab Terjadinya Post Partum Blues dengan Skrining Edinburgh Postnatal Depression Scale (EPDS)

2019 ◽  
Vol 9 (2) ◽  
pp. 126-136
Author(s):  
Adriani
Keyword(s):  
Postnatal Depression ◽  
Edinburgh Postnatal Depression Scale ◽  
Post Partum ◽  
Depression Scale ◽  
Cross Sectional ◽  
Postpartum Blues

Abstrak Perubahan peran seorang wanita menjadi seorang ibu tidaklah selalu berupa hal yang menyenangkan saja bagi pasangan suami istri, kadang kala terjadi terjadi konflik baik didalam diri wanita tersebut maupun konflik dengan suami. Jika perhatian terhadap keadaan psikologis ibu post partum kurang maka dapat menyebabkan ibu akan cenderung untuk mencoba mengatasi permasalahannya atau ketidaknyamanannya tersebut sendiri, keadaan ini jika dibiarkan saja dapat menyebabkan ibu post partum mengalami postpartum blues. Di Indonesia, diperkirakan terdapat 50-70% ibu pasca melahirkan mengalami postpartum blues pada hari 4-10. Penelitian ini menggunakan survey analitik dengan desain penelitian cross sectional, dengan jumlah sampel sebanyak 160 orang. Data diambil menggunakan kuesioner yang ditampilkan dalam analisa univariat dan bivariat menggunakan sistem komputerisasi SPSS. Hasil penelitian yaitu ada hubungan antara pendidikan ibu (p 0,013), pekerjaan ibu (p 0,013), dukungan suami (p 0,021), pendapatan keluarga dengan kejadian post partum blues (p 0,000) dan tidak ada hubungan antara paritas ibu (p 0,199), umur ibu (p 0,391), dan riwayat PMS (p 0,087) dengan kejadian post partum blues. Diharapkan bagi peneliti untuk dapat melanjutkan penelitian dengan variabel yang lebih bergam dan diharapkan bagi para tenaga kesehatan agar dapat meningkatkan pelayanan terutama dalam pemberian dukungan pada ibu masa post partum, sehingga mengurangi resiko ibu mengalami postpartum blues. Kata kunci : Postpartum blues, pendidikan, pekerjaan, dukungan suami, riwayat PMS

Maternal anxiety and depression in pregnancy and DNA methylation of the NR3C1 glucocorticoid receptor gene

Epigenomics ◽  
2020 ◽  
Author(s):  
Alexandra E Dereix ◽  
Rachel Ledyard ◽  
Allyson M Redhunt ◽  
Tessa R Bloomquist ◽  
Kasey JM Brennan ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Depressive Symptoms ◽  
Trait Anxiety ◽  
Cpg Island ◽  
Depression Scale ◽  
Maternal Anxiety ◽  
Anxiety And Depression ◽  
Pregnancy Anxiety ◽  
Glucocorticoid Receptor Gene ◽  
Island Shore

Aim: To quantify associations of anxiety and depression during pregnancy with differential cord blood DNA methylation of the glucorticoid receptor ( NR3C1). Materials & methods: Pregnancy anxiety, trait anxiety and depressive symptoms were collected using the Pregnancy Related Anxiety Scale, State-Trait Anxiety Index and Edinburgh Postnatal Depression Scale, respectively. NR3C1 methylation was determined at four methylation sites. Results: DNA methylation of CpG 1 in the NR3C1 CpG island shore was higher in infants born to women with high pregnancy anxiety (β 2.54, 95% CI: 0.49–4.58) and trait anxiety (β 1.68, 95% CI: 0.14–3.22). No significant association was found between depressive symptoms and NR3C1 methylation. Conclusion: We found that maternal anxiety was associated with increased NR3C1 CpG island shore methylation.

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