Somatic Symptoms As Measured By Ssi-26 (somatic Symptom Inventory) Correlate With Social And Physical Functioning (sf36) In Depressed Patients. The Relative Contribution Of Anhedonia

According to the DSM5, Somatic Symptom Disorder (SSD) is characterized by somatic symptoms that are either very distressing or result in significant disruption of functioning. These criteria are significantly different compared with previous editions of DSM. For example, the DSM-IV diagnosis of somatization disorder required a specific number of complaints from among four symptom groups, however the SSD criteria no longer have such a requirement. Nevertheless somatic symptoms must be significantly distressing or disruptive to daily life. Very few studies have focussed on the influence of suffering anhedonia on the perception of somatic symptoms and how this impact on Health Related Quality of Life (HRQoL), particularly physical functioning. We studied the relative impact of somatic symptoms on the social and physical functioning in depressed patients. Moreover we have explored the influence of anhedonia as measured by the Snaith-Hamilton Anhedonia Pleasure Scale (SHAPS). We analysed the correlations between the scores of the 8 dimensions of the SF-36, the SSI-26 and the SHAPS questionnaires. The results show a significant correlation between SSI-26 score and physical functioning (r = –0.565; P < 0.001), role physical (r = –0.551; P < 0.001), bodily pain (r = –0.659; P < 0.001), general health (r = –0.534; P < 0.001), vitality (r = –0.481; P = 0.001), social functioning (r = –0.302; P = 0.044) and mental health (r = –0.461; P = 0.001). Additionally, SHAPS score correlates with vitality (r = –0.371; P = 0.012), social functioning (r = –0.574; P < 0.001) and mental health (r = –0.445; P = 0.002). The results demonstrated that both somatic symptoms and level of anhedonia negatively correlate with HRQoL, suggesting a potential relationship between level of anhedonia and some somatic symptoms. This could impact on the diagnosis and treatment of depressed patients with somatic symptoms and anhedonia.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Improved Health-Related Quality of Life in Patients with Hematological Disorders Receiving Deferasirox (Exjade®)

Blood ◽

10.1182/blood.v112.11.1307.1307 ◽

2008 ◽

Vol 112 (11) ◽

pp. 1307-1307 ◽

Cited By ~ 5

Author(s):

John B Porter ◽

Donald Bowden ◽

Arnold Ganser ◽

Gabor Domokos ◽

Adam Gater ◽

...

Keyword(s):

Mental Health ◽

Social Functioning ◽

Physical Functioning ◽

General Health ◽

Bodily Pain ◽

Hematological Disorders ◽

Role Emotional ◽

Role Physical ◽

Sf 36 ◽

Domain Scores

Abstract Introduction: Iron chelation therapy (ICT) is essential in removing excess iron deposited in body organs, ultimately preventing organ failure and extending the lives of patients (pts) with transfusion-dependent hematological disorders such as β-thalassemia and myelodysplastic syndromes (MDS). As a life-long treatment, traditional ICT (deferoxamine, Desferal®, DFO) is based on a burdensome regimen (subcutaneous delivery 5–7 times a week) that has been shown to negatively impact on pts’ health-related quality of life (HRQoL). The oral chelator deferasirox (Exjade®) is less burdensome to pts offering 24-hour ICT, 7 days a week. Methods: This substudy was part of a single arm, multicenter, 1-year open-label trial (the EPIC study) to investigate the efficacy/safety of deferasirox. The first 558 pts with a variety of hematological disorders were recruited. These pts came from sites in seven countries: Australia, Belgium, France, Germany, UK, Greece, and Italy. Treatment-naïve pts and those having previously received ICT (DFO or deferiprone [Ferriprox®] exclusively, or combined) participated (n=558). Pts were asked at baseline, week 4 and week 52 (end of study [EOS]) to complete the 36-item Short Form health survey (SF-36). The SF-36 is a self-administered questionnaire and measures eight HRQoL domains: physical functioning; role-physical; bodily pain; general health; vitality; social functioning; role-emotional; and mental health. Mean change in SF-36 domain scores were calculated for all pts who had completed data at baseline and week 4, as well all those with completed data at baseline and EOS. All domains are scored so that higher scores indicate a better QoL. Results: Overall, the mean age of the 558 pts (274 β-thalassemia, 168 MDS, 50 sickle cell disease and 66 other anemias) recruited to take part in this substudy was 40.8 years (SD=22.58); 51.5% of patients (n=289) were male and 48.5% (n=272) were female. Within this sample, 337 pts aged ≥16 years completed the SF-36 at baseline, 322 at week 4 and 277 at EOS. Mean domain scores for pts at baseline, week 4 and EOS are presented in Table 1. With the exception of role-emotional (mean=0.78, SD=40.56), mean change in SF-36 domain scores significantly improved (P<0.05) for all domains between baseline and week 4: physical functioning (mean=2.42, SD=17.44); role-physical (mean=5.67, SD=41.70); bodily pain (mean=5.96, SD=24.15); general health (mean=0.33, SD=14.44); vitality (mean=2.54, SD=15.93); social functioning (mean=2.51, SD=23.38); mental health (mean=1.98, SD=14.71). At EOS, mean change in SF-36 domain scores improved for all domains with the exception of social functioning, role-emotional and mental health. However, unlike results at week 4, none of the mean change domain scores at EOS reached statistical significance, possibly due to sample size decrease between week 4 and EOS. Table 1. SF-36 domain scores at baseline, week 4 and EOS in pts aged 3 16 years and treated with deferasirox SF-36 domains Baseline mean (SD) Week 4 mean (SD) End of study mean (SD) Physical functioning 66.32 (25.98)  n=336 69.70 (25.98)  n=317 71.67 (26.95)  n=275 Role-physical 54.33 (42.43) n=331 61.03 (42.69) n=315 62.38 (41.71) n=270 Bodily pain 65.80 (26.89)  n=336 74.67 (26.16)  n=322 73.11 (27.20)  n=276 General health 46.62 (21.15)  n=330 48.01 (22.32)  n=311 48.42 (22.19)  n=269 Vitality 51.12 (21.28)  n=328 54.57 (22.06)  n=316 55.80 (23.06)  n=272 Social functioning 71.73 (25.74)  n=336 74.77 (23.72)  n=321 73.05 (24.71)  n=276 Role-emotional 68.05 (40.92)  n=326 69.60 (41.60)  n=313 69.81 (40.44)  n=270 Mental health 67.04 (19.85)  n=328 70.40 (19.73)  n=316 67.85 (20.19)  n=272 Conclusions: Since mean change scores were often of the magnitude of 3 to 5 units for role-physical and bodily pain, these results indicate clinically meaningful improvement for pts with hematological disorders receiving deferasirox.

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Health-Related Quality of Life Among Vietnamese Breast Cancer Women

Cancer Control ◽

10.1177/1073274819862787 ◽

2019 ◽

Vol 26 (1) ◽

pp. 107327481986278 ◽

Cited By ~ 2

Author(s):

Thanh Huong Tran ◽

Ngoc Linh Trinh ◽

Yen Hoang ◽

Thuy Linh Nguyen ◽

Thu Thao Vu

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Mental Health ◽

Social Functioning ◽

Physical Functioning ◽

Bodily Pain ◽

Health Related Quality ◽

Related Quality ◽

Health Related

The aim of the study was to investigate health-related quality of life among Vietnamese breast cancer women who were treated at National Cancer Hospital, Hanoi, Vietnam, in 2018. Information about physical functioning, Role Physical, Bodily Pain, General Health, vitality, Social Functioning, Role Emotional, and Mental Health of 200 patients with breast cancer was collected through face-to-face interview, using short form-36 questionnaire. We found that the older patients (older than 50 years) had higher score of Mental Health than patients at age 50 and lower ( P < .05). The patients who had better economic status had significantly higher score of Vitality ( P < .05). Patients who were married and living with their partners/husband had better quality of life in General Health ( P<0.05). The patients who had less than 6 months of treatment had better physical functioning score ( P < .05) than the patients who had treatment longer than 6 months. Patients with caring supports from family members had higher scores of Bodily Pain, Social Functioning, Role Emotional, and Mental Health. Patients who have stressed feelings had significantly lower scores of all domains, except for Physical Functioning. The participants who usually stay up late reported lower scores of all components except for Physical Functioning and Role Physical. In conclusion, it is needed to develop psychosocial services, enhance early screening, and diagnose for the women in Vietnam.

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A functional electric orthesis on the paretic leg improves quality of life of stroke patients

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2006000100005 ◽

2006 ◽

Vol 64 (1) ◽

pp. 20-23 ◽

Cited By ~ 9

Author(s):

Mara Renata Fernandes ◽

Luciane B.C. Carvalho ◽

Gilmar F. Prado

Keyword(s):

Quality Of Life ◽

Social Functioning ◽

Physical Functioning ◽

Bodily Pain ◽

Improve Quality ◽

Stroke Patients ◽

Normal Life ◽

Sf 36 ◽

Before And After

CONTEXT: Hemiparesia changes quality of life of patients with stroke making difficult a normal life. OBJECTIVE: To evaluate the effect of Functional Eletric Orthesis (FEO) applied over the paretic leg in the quality of life of stroke patients. METHOD: The quality of life of 50 stroke patients of Associacao de Assistencia a Crianca Deficiente (AACD) was evaluated with SF-36 questionnaire before and after the treatment with a FEO for rehabilitation of walking. We analyzed data according to gender and affected hemisphere. RESULTS: The average values from all domains of SF-36 improved significantly (p<0.001). Female patients improved more than male in Emotional Domain (p=0.04) and presented a trend to be better regarding Bodily Pain and Social Functioning. Patients with right hemiparesia improved more than those with left hemiparesia (p=0.02). CONCLUSION: FEO over a paretic leg is efficient to improve quality of life of stroke patients, mainly Physical Functioning.

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Muscular strain as risk factor of somatic symptom of mix anxiety and depression

European Psychiatry ◽

10.1016/j.eurpsy.2017.01.333 ◽

2017 ◽

Vol 41 (S1) ◽

pp. S406-S406

Author(s):

M. Bhadar ◽

S. Asghar ◽

Z. Mukhtar

Keyword(s):

Poor Prognosis ◽

Somatic Symptom ◽

Somatic Symptoms ◽

The Body ◽

Anxiety And Depression ◽

Body Parts ◽

Muscular Tension ◽

Increased Risk ◽

Severity Of Depression ◽

Competing Interest

IntroductionSomatic symptoms in depression are not uncommon. There is increased sicidality, poor prognosis, and increased risk of relapse. Neurological and l muscloskeletal symptoms can be explained on basis of increased muscular tension in the body.MethodsAn internet search was made using key words muscular tension, SSRIs depression, anxiety, somatic symptoms.ResultsNinety-eight percent patients reported at least one of somatic symptoms. Forty-five percent reported six somatic symptom. GIT symptoms in 67% patients. Fatigue in 78% % of patients. Weakness in body parts 45% and headache in 43% to 65%. Chest pain more common in male. Patient over 40 showed pain in limbs or joints. Number of symptoms was directly related to severity of depression.DiscussionIncreased muscular tension is one component of mix anxiety and depression. Main nerves and their branches pass in between muscular bellies. When there is increased muscular tone, it puts extra compression on major nerves and their branches. This will cause dysesthesia in body parts. Stretching of muscles produce pain due to hypoxia. This produces headache, strain neck and backache pain in chest. Fatigue is result of over consumption of energy due to hypertonia. One of their side effect is of SSRIs is muscular hypertonia which will not be very helpful for these symptoms. Drugs like tricyclics, SNRI can have better results when used alone, gabapentine, pregabline tinazidine used as adjunct can alleviate symptoms. Non-pharmacological treatment includes massage, relaxation technique, and warm water therapy.ConclusionSomatic symptoms of mix anxiety and depression should be important consideration in its treatment.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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13-year Follow-up of Treatment of Osteochondral Lesions with MACI

Foot & Ankle Orthopaedics ◽

10.1177/2473011419s00044 ◽

2019 ◽

Vol 4 (4) ◽

pp. 2473011419S0004 ◽

Cited By ~ 1

Author(s):

Chris Kreulen ◽

Trevor Shelton ◽

Jacqueline Nguyen ◽

Eric Giza ◽

Martin Sullivan

Keyword(s):

Social Functioning ◽

Physical Functioning ◽

Bodily Pain ◽

Long Term Results ◽

Osteochondral Lesions ◽

Sf 36 ◽

Significant Difference ◽

And Function

Category: Ankle, Arthroscopy, Hindfoot, Sports, Trauma Introduction/Purpose: Surgical management of osteochondral lesions of the talus (OLT) present an ongoing treatment challenge. Previously, matrix-induced autologous chondrocyte implantation (MACI) demonstrated improved pain and function at 7-years postoperative, providing evidence that MACI is a reliable method for treating cartilage. However, it is unknown the long- term results of MACI in OLT. The purpose of this study was to assess 13-year clinical follow-up data and the long-term success of this implant by comparing patient reported outcome measures (PROMs) pre-operatively, at 7-years post-operative, and at 13- years post-operative. Methods: A prospective investigation of MACI was performed on 10 patients with OLTs who had failed previous arthroscopic treatment. Of the 10 patients, 9 were available for 7-year and 13-year follow-up. Short Form Health Survey (SF-36) and the American Orthopaedic Foot & Ankle Society (AOFAS) hindfoot evaluation were utilized at pre-operative, 7-year, a 13-year postoperative. For each patient, a paired t-test was used to compare 13-year post-operative PROMs to pre-operative PROMs. A single factor analysis of variance (ANOVA) determined whether PROMs were different between pre-operative, 7-year post- operative, and 13-year post-operative time intervals. When a significant difference was detected, a post-hoc Tukey’s determined which time periods were different. Results: SF-36 data at 13-years showed significant improvements in Physical Functioning (p=0.012), Lack of Bodily Pain (p=0.017), and Social Functioning (p=0.007) compared with preoperative data. There were no differences in other components of the SF-36 outcomes (p>0.05). Although the AOFAS was on average 12 points higher at 13-years postoperative, this was not statistically significant (p=0.173). As for comparing PROMs over time, 13-years post-operative PROMs were comparable to 7-years post- operative (Table 1). There were better PROMs for Physical Functioning, Bodily Pain, and Social Functioning at 7- and 13-years post-operative compared to pre-operative while Physical Role Functioning was also better at 7-years post-operative compared to pre-operative. Conclusion: This study shows MACI provides greater pain relief and function at 13-years post-operative with stable long-term follow-up. MACI should be considered for osteochondral lesions that fail initial microfracture.

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Evaluation of Graft Tensioning Effects in Anterior Cruciate Ligament Reconstruction between Hamstring and Bone–Patellar Tendon Bone Autografts

The Journal of Knee Surgery ◽

10.1055/s-0039-3402046 ◽

2020 ◽

Cited By ~ 3

Author(s):

Steven F. DeFroda ◽

Naga Padmini Karamchedu ◽

Ross Budacki ◽

Taylor Wiley ◽

Paul D. Fadale ◽

...

Keyword(s):

Mental Health ◽

Anterior Cruciate Ligament ◽

Social Functioning ◽

Cruciate Ligament ◽

Bodily Pain ◽

Graft Tension ◽

High Tension ◽

Sf 36 ◽

Anterior Cruciate ◽

Low Tension

AbstractThis article investigates the clinical, functional, and radiographic outcomes in anterior cruciate ligament (ACL) reconstruction patients over 7 years to determine the effects of initial graft tension on outcomes when using patellar tendon (bone–tendon–bone [BTB]) and hamstring tendon (HS) autografts. Ninety patients, reconstructed with BTB or HS, were randomized using two initial graft tension protocols: (1) normal anteroposterior (AP) laxity (“low-tension”; n = 46) and (2) AP laxity overconstrained by 2 mm (“high-tension”; n = 44). Seventy-two patients had data available at 7 years, with 9 excluded for graft failure. Outcomes included the Knee Injury and Osteoarthritis Outcome Score, Short-Form-36 (SF-36), and Tegner activity scale. Clinical outcomes included KT-1000S and International Knee Documentation Committee examination score; and functional outcomes included 1-leg hop distance and peak knee extensor torque. Imaging outcomes included medial joint space width, Osteoarthritis Research Society International radiographic score, and Whole-Organ Magnetic Resonance Score. There were significantly improved outcomes in the high-tension compared with the low-tension HS group for SF-36 subset scores for bodily pain (p = 0.012), social functioning (p = 0.004), and mental health (p = 0.014) 84 months postsurgery. No significant differences in any outcome were found within the BTB groups. Tegner activity scores were also significantly higher for the high-tension HS group compared with the low-tension (6.0 vs. 3.8, p = 0.016). Patients with HS autografts placed in high tension had better outcomes relative to low tension for Tegner activity score and SF-36 subset scores for bodily pain, social functioning, and mental health. For this reason, we recommend that graft fixation be performed with the knee at 30-degree flexion (“high-tension” condition) when reconstructing the ACL with HS autograft.

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Corrleation of health-related quality of life (HRQL) of cancer patients and the mental component parameters of their family members

Journal of Clinical Oncology ◽

10.1200/jco.2009.27.15_suppl.e20619 ◽

2009 ◽

Vol 27 (15_suppl) ◽

pp. e20619-e20619

Author(s):

I. Vrettos ◽

A. Papadopoulos ◽

K. Kamposioras ◽

D. Charitos ◽

G. Giannopoulos ◽

...

Keyword(s):

Mental Health ◽

Social Functioning ◽

Cancer Patients ◽

General Health ◽

Bodily Pain ◽

Family Members ◽

Sf 36 ◽

Related Quality ◽

Health Related ◽

Highly Correlated

e20619 Background: It is widely experienced that health-related quality of life (HRQL) is greatly influenced in the family members of cancer patients. The aim of this study was to find the correlation of the HRQL parameters in cancer patients with the main mental component parameters of patients’ relatives. Methods: 122 cancer patients undergoing chemotherapy in our department (49 men and 73 women) of mean age 56.6 ±15.4 1SD and their 122 relatives that accompanied them (45 men and 77 women) of mean age 48.3 ±14.5 completed the validated SF-36 health survey by personal interview. The SF-36 health survey summarizes the functional health status and general health into eight scales with higher scores (0–100 range) reflecting better-perceived health. In this study, physical functioning (PF), role physical (RP), bodily pain (BP), general health perception (GH), vitality (VT), social functioning (SF), role emotional (RE), and mental health (MH) of the patients were correlated with the SF, RE, MH of their family members using the Spearman's test. Data analysis was performed with SPSS version 13.0 and correlations were considered statistically significant when p<0.05. Results: Table 1 summarizes the results of our study. Social Functioning and Mental Health of family members are highly correlated with the HRQL parameters of cancer patients. The RE does not seem to be affected. Conclusions: HRQL of cancer patients undergoing chemotherapy is highly correlated with the SF and the MH of their relatives. This observation highlights the need to develop more oriented supportive programs for both the patients and their family memebers. Abbreviations: PF = Physical Functioning, RP = Role Physical, BP = Bodily Pain, GH = General Health, VT = Vitality, SF = Social Functioning, RE = Role Emotional, MH = Mental Health; NS=Not Significant. * = 0.05. ** = 0.01. [Table: see text] No significant financial relationships to disclose.

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Loneliness and Mental Health: The Mediating Effect of Perceived Social Support

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph182211963 ◽

2021 ◽

Vol 18 (22) ◽

pp. 11963

Author(s):

Elody Hutten ◽

Ellen M. M. Jongen ◽

Anique E. C. C. Vos ◽

Anja J. H. C. van den Hout ◽

Jacques J. D. M. van Lankveld

Keyword(s):

Mental Health ◽

Social Support ◽

Social Connectedness ◽

Somatic Symptom ◽

Somatic Symptoms ◽

Mediating Effect ◽

Somatic Symptom Disorder ◽

Physical And Mental Health ◽

Anxiety Depression ◽

The Relationship

Social connectedness is a fundamental human need. The Evolutionary Theory of Loneliness (ETL) predicts that a lack of social connectedness has long-term mental and physical health consequences. Social support is a potential mechanism through which loneliness influences health. The present cross-sectional study examined the relationship between loneliness and mental health, and the mediating effects of social support in a Dutch adult sample (N = 187, age 20 to 70). The health variables included in the study are anxiety, depression, somatic symptoms as measured by the SCL-90, and the DSM-5 diagnosis somatic symptom disorder. The results indicated that social support partially mediated the relationship between loneliness and anxiety, depression, and somatic symptoms. These results indicate that social support partially explains the relationship between loneliness and physical and mental health issues. The relationship between loneliness and being diagnosed with somatic symptom disorder was not mediated by social support. This suggests that the mechanisms through which loneliness relates to either somatic symptoms or somatic symptom disorder are different.

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Comparing Cognitive and Somatic Symptoms of Depression in Myocardial Infarction Patients and Depressed Patients in Primary and Mental Health Care

PLoS ONE ◽

10.1371/journal.pone.0053859 ◽

2013 ◽

Vol 8 (1) ◽

pp. e53859 ◽

Cited By ~ 8

Author(s):

Nynke A. Groenewold ◽

Bennard Doornbos ◽

Marij Zuidersma ◽

Nicole Vogelzangs ◽

Brenda W. J. H. Penninx ◽

...

Keyword(s):

Mental Health ◽

Myocardial Infarction ◽

Health Care ◽

Mental Health Care ◽

Somatic Symptoms ◽

Symptoms Of Depression ◽

Depressed Patients

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Case Report: Somatic Symptoms Veiling Gender Dysphoria in an Adolescent

Frontiers in Pediatrics ◽

10.3389/fped.2021.679004 ◽

2021 ◽

Vol 9 ◽

Author(s):

Giuliana Morabito ◽

Dora Cosentini ◽

Gianluca Tornese ◽

Giulia Gortani ◽

Serena Pastore ◽

...

Keyword(s):

Mental Health ◽

Diagnostic Tests ◽

Gender Dysphoria ◽

Somatic Symptom ◽

Somatic Symptoms ◽

Hospital Services ◽

Somatic Symptom Disorder ◽

Case Presentation ◽

Psychosocial Impairment ◽

History Of

Background: Somatic symptom disorder is common in children and adolescents; usually, it is an expression of a mental health problem or other conditions that lead to psychosocial impairment and suffering. Among these, in pubertal age, gender dysphoria should be considered.Case Presentation: We present the case of a 15-year-old girl admitted to the hospital because of a 2-month history of scattered arthralgia and myalgia, headache, and fatigue, with repeated visits to the emergency room. The physical exam was unremarkable, except for step walking and pain. Repeated diagnostic tests were normal, and consecutive psychological interviews disclosed intense suffering due to a gender incongruence. Referral to the hospital gender service was offered and refused by the parents.Conclusions: In pubertal age, gender dysphoria may be expressed through somatoform symptoms. Diagnosis is challenging to accept for the parents even in the presence of adequate multi-disciplinary hospital services.

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