Is fenofibrate a cost-saving treatment for middle-aged individuals with type II diabetes? An economic analysis of the FIELD Study

2008 ◽  
Vol 127 (1) ◽  
pp. 51-56 ◽  
Author(s):  
Melinda Carrington ◽  
Simon Stewart
Keyword(s):  
Cost Saving ◽  
Economic Analysis ◽  
Field Study ◽  
Type Ii Diabetes ◽  
Type Ii ◽  
Middle Aged

scholarly journals The effectiveness of health literacy oriented programs on physical activity behaviour in middle aged and older adults with type 2 diabetes: a systematic review

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Michael Huen Sum Lam ◽  
Angela Yee Man Leung
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Older Adults ◽  
Health Literacy ◽  
Type Ii Diabetes ◽  
Physical Activity Behavior ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
Middle Aged ◽  
Activity Behavior

Health literacy is the first step to self-management of type II diabetes mellitus, of which physical activity is the least compliant behavior. However, no reviews have summarized the effect and the process of interventions of health literacy oriented programs on physical activity behavior among middle aged and older adults with type II diabetes mellitus. This article is the first to examine the effectiveness of health literacy oriented programs on physical activity behavior among middle aged and older adults with type II diabetes mellitus. This systematic review extracted articles from nine electronic databases between 1990 and 2013. Six interventional studies were extracted and reported in accordance with the guidance of Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Findings demonstrated that health literacy oriented programs increased the frequency and duration of physical activity among patients with high health literacy. Although some studies effectively improved the health literacy of physical activity, gap in literature remains open for the indistinct and unreliable measurement of physical activity within self-management programs of type II diabetes mellitus, and the questionable cross-culture generalizability of findings. Further studies with well-knit theorybased intervention with respect to patients’ cultural background, duration of intervention and objective measurements are encouraged to elucidate the relationship between health literacy oriented programs and physical activity behavior.

Macroangiopathy in type II diabetes

1983 ◽  
Vol 104 (4_Suppl) ◽  
pp. S75-S78
Author(s):  
Antti Aro
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Vascular Disease ◽  
Peripheral Vascular Disease ◽  
Type Ii Diabetes ◽  
Clinical Manifestations ◽  
Diabetic Patients ◽  
Type Ii ◽  
Peripheral Vascular ◽  
Middle Aged

ABSTRACT. Macroangiopathy is the most important cause of mortality and morbidity in type II diabetes. The atherosclerotic process in diabetes is similar to that found in non-diabetic subjects, but the laesions are more extensive and the clinical manifestations are more common in diabetic subjects than in the non-diabetic population. In diabetic patients from different populations, the prevalence of macroangiopathy is variable, and the relative frequency follows the pattern found in the respective non-diabetic populations. The relative risk of large vessel disease is in most populations higher for female than for male diabetics. Coronary heart disease is the most important manifestation of macroangiopathy while cerebrovascular disease and peripheral vascular disease are less frequent, although all these manifestations occur at increased frequency among middle-aged diabetic subjects. The incidence of peripheral vascular disease seems to increase with increasing duration of diabetes in middle-aged subjects, whereas coronary heart disease is particularly frequent in type II diabetes already at the time of the diagnosis. Key words: atherosclerosis, complications, diabetes mellitus, macroangiopathy, mortality.

Abstract P323: Sleep Debt and Type II Diabetes Mellitus in Middle Aged and Older Women

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Jonathan Z Butler ◽  
Natalie Slopen ◽  
Susan Redline ◽  
Alan M Zaslavsky ◽  
David R Williams ◽  
...  
Keyword(s):  
Older Women ◽  
Sleep Duration ◽  
Type Ii Diabetes ◽  
Sleep Disturbances ◽  
Acute Stress ◽  
Statistical Significance ◽  
Health Study ◽  
Type Ii ◽  
Middle Aged ◽  
Sleep Debt

Background: Sleep disturbances can be both a cause and consequence of circadian disruption resulting in cardiometabolic dysregulation. However, little is known about sleep debt, defined as the average sleep duration difference >=2 hours between weekend versus weekday and type II diabetes (T2D) mellitus particularly in older women. Methods and Results: We analyzed 25,335 women free of cardiovascular disease (CVD) in the ongoing follow-up cohort from the Women’s Health Study (WHS). Utilizing the WHS stress questionnaire (2012-13) that assessed sleep duration among other chronic and acute stress measures, we computed sleep debt as the average sleep duration difference >=2 hours between weekend versus weekday. Of the 2539 women with physician confirmed T2D at the time of questionnaire administration, 216 women had sleep debt. Mean age for women with sleep debt and T2D versus no sleep debt and diabetes were 69.3 ± 4.4 and 72.7 +/- 6.1 years old respectively. Women with sleep debt and T2D were younger, more likely to have hypertension and hypercholesterolemia, use alcohol, be current smokers, had higher body mass index and be anxious or depressed. In logistic regression analyses, women with sleep debt had a 47% higher odds of T2D independent of age, race/ethnicity, and socioeconomic status (income and education) [odds ratio (OR): 1.47, 95% confidence interval (CI): 1.25 to 1.72, P<0.0001]. Adjustment for CVD risk factors, depression and anxiety symptoms resulted in attenuation of the relationship which maintained statistical significance [OR: 1.31, 95% CI: 1.10 to 1.55, P= 0.0002]. When cumulative psychological stress (combination of chronic and acute stressors: e.g., life events, job stress, discrimination) was accounted for, the observed relationship between sleep debt and T2D persisted [OR: 1.28, 95% CI 1.09 to 1.53, P= 0.004]. (Table 1) Conclusion: Sleep debt was associated with higher odds of type 2 diabetes prevalence in middle-aged and older women.

scholarly journals Development and psychometric properties of a new social support scale for self-care in middle-aged patients with type II diabetes (S4-MAD)

2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Shohreh Naderimagham ◽  
Shamsaddin Niknami ◽  
Farid Abolhassani ◽  
Ebrahim Hajizadeh ◽  
Ali Montazeri
Keyword(s):  
Social Support ◽  
Psychometric Properties ◽  
Type Ii Diabetes ◽  
Self Care ◽  
Type Ii ◽  
Middle Aged ◽  
Aged Patients ◽  
Social Support Scale

Social Support Scale for Self-Care in Middle-Aged Patients with Type II Diabetes

2012 ◽  
Author(s):  
Shohreh Naderimagham ◽  
Shamsaddin Niknami ◽  
Farid Abolhassani ◽  
Ebrahim Hajizadeh ◽  
Ali Montazeri
Keyword(s):  
Social Support ◽  
Type Ii Diabetes ◽  
Self Care ◽  
Type Ii ◽  
Middle Aged ◽  
Aged Patients ◽  
Social Support Scale

Plasma insulin and C-peptide in relation to glucose intolerance in middle-aged men

1982 ◽  
Vol 100 (2) ◽  
pp. 262-265 ◽  
Author(s):  
Jörgen Malmquist ◽  
Folke Lindgärde ◽  
Karl-Fredrik Eriksson ◽  
Elisabet Johansson
Keyword(s):  
Diabetes Mellitus ◽  
Type Ii Diabetes ◽  
Plasma Insulin ◽  
Type Ii Diabetes Mellitus ◽  
Immunoreactive Insulin ◽  
Type Ii ◽  
Cell Secretion ◽  
Middle Aged ◽  
C Peptide ◽  
Type Ii Diabetics

Abstract. The relation between glucose homeostasis and insulin secretion (immunoreactive insulin and C-peptide) was studied in middle-aged males matched for age and body weight. Subjects with mild type II diabetes mellitus were compared to normals and to individuals with impaired glucose tolerance (IGT). In addition, the diabetics were subdivided according to duration, some of the subjects having recently deteriorated from IGT status. In the IGT individuals, there were no indications of a reduction in basal or glucose-induced insulin output. On the contrary, data indicate somewhat higher than normal secretion. Within the type II diabetics, those of short duration were largely similar to normals, whereas diabetes of longer duration was associated with some diminution in indices of B cell secretion. The data support the notion that a deficient insulin output is not a primary pathophysiological event in the development of type II diabetes.

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