Microsporidia as emerging pathogens and the implication for public health: A 10-year study on HIV-positive and -negative patients

2012 ◽  
Vol 42 (2) ◽  
pp. 197-205 ◽  
Author(s):  
Maria Luísa Lobo ◽  
Lihua Xiao ◽  
Francisco Antunes ◽  
Olga Matos
Keyword(s):  
Public Health ◽  
Hiv Positive ◽  
Emerging Pathogens

scholarly journals Leveraging Local Expertise in Stewardship, Hospital Epidemiology and Public Health to Enrich Postgraduate Training in NYC

2020 ◽  
Vol 41 (S1) ◽  
pp. s311-s312
Author(s):  
Kelsie Cowman ◽  
Belinda Ostrowsky ◽  
Susan Seo ◽  
Victor Chen ◽  
Rachel Bartash ◽  
...  
Keyword(s):  
Public Health ◽  
New York ◽  
Case Studies ◽  
Postgraduate Training ◽  
Medical Center ◽  
Effective Means ◽  
Emerging Pathogens ◽  
Hospital Epidemiology ◽  
Full Day ◽  
Epidemiology And Public Health

Background: New York City is a gateway for emerging pathogens and global threats. In 2013, faculty from Montefiore Medical Center and Memorial Sloan Kettering developed a free half-day workshop for postgraduate trainees in antimicrobial stewardship (AS), infection prevention (IP), hospital epidemiology, and public health. This annual workshop, sponsored by the Infectious Diseases Society of New York (IDSNY), incorporates case studies and expert panel discussions on timely topics such as Ebola, Candida auris, Clostridiodes difficile, measles, nosocomial influenza, drug shortages, and AS/IP “big data.” Methods: From 2013 through 2017, the workshop involved 10–15 interactive AS/IP cases with audience response questions and panel discussions. In 2018–2019, based on feedback, the format was revised to emphasize breakout sessions in which participants actively practiced AS/IP tools, (eg, medication utilization evaluations, epidemiologic curves, and performance improvement devices). Examples of 2018–2019 cases are shown in Figure 1. A pre- and postseminar paper survey was conducted yearly to understand baseline training in AS/IP, desire for future AS/IP careers, and self-reported effectiveness of the workshop. Results: Initially, the primary audience was NYC ID fellows. From 2018 onward, we opened enrollment to pharmacy residents. Approximately 45 NYC ID fellows were eligible for the course each year. Results from 2013 to 2016 surveys were reported previously (Fig. 2). There were 32 attendees in 2018, 42 in 2019. The survey response rate was 88% in 2018 and 95% in 2019, with 68 (92%) total participants. Most participants had received previous training in IP (82%) and AS (94%) (Fig. 3). Most participants reported that the program was a good supplement to their ID training (98%) and that case studies were an effective means of learning IP (100%) and AS (98%). Furthermore, 92% stated they would like additional AS/IP training, and many since 2013 have requested a full-day course. Self-reported interest in future involvement in AS/IP increased after the workshop: IP, 68%–83% (P =.04) and AS, 88%–91% (P = .61). Conclusions: Most trainees reported satisfaction with the workshop and case-study learning method; interest in future AS/IP careers increased after the seminar. We intend to explore Funding: to expand to a full-day program for all NYC postgraduate trainees and AS/IP junior faculty. As such, we hope to obtain the endorsement of professional societies such as SHEA. This workshop could address a crucial educational gap in AS/IP postgraduate training and help sustain our future workforce.Funding: NoneDisclosures: None

scholarly journals Whole genome sequencing based differentiation between re-infection and relapse in Indian patients with tuberculosis recurrence, with and without HIV co-infection

2020 ◽  
Author(s):  
Sivakumar Shanmugam ◽  
Nathan L Bachmann ◽  
Elena Martinez ◽  
Ranjeeta Menon ◽  
Gopalan Narendran ◽  
...  
Keyword(s):  
Public Health ◽  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Repeat Unit ◽  
Hiv Positive ◽  
Whole Genome ◽  
Immunodeficiency Virus ◽  
High Contribution ◽  
Tuberculosis Recurrence ◽  
Hiv Negative

AbstractDifferentiation between relapse and reinfection in cases with tuberculosis (TB) recurrence has important implications for public health, especially in patients with human immunodeficiency virus (HIV) co-infection. Forty-one paired M. tuberculosis isolates collected from 20 HIV-positive and 21 HIV-negative patients, who experienced TB recurrence after previous successful treatment, were subjected to whole genome sequencing (WGS) in addition to spoligotyping and mycobacterial interspersed repeat unit (MIRU) typing. Comparison of M. tuberculosis genomes indicated that 95% of TB recurrences in the HIV-negative cohort were due to relapse, while the majority of TB recurrences (75%) in the HIV-positive cohort was due to re-infection (P=0.0001). Drug resistance conferring mutations were documented in four pairs (9%) of isolates associated with relapse. The high contribution of re-infection to TB among HIV patients warrants further study to explore risk factors for TB exposure in the community.

The Public Health Police

2017 ◽  
Author(s):  
Trevor Hoppe
Keyword(s):  
Public Health ◽  
Hiv Positive ◽  
Local Health ◽  
Health Departments ◽  
Adherence To Treatment ◽  
The Public ◽  
Treatment Regimens ◽  
Health Authorities ◽  
Public Health Authorities ◽  
Local Health Authorities

As the HIV epidemic wore on in the 2000s, public health authorities became enamored with the idea of “ending AIDS.” That is, if they could just get HIV-positive people to take their pills and stop infecting other people. Health departments began to track HIV-positive clients more closely, aiming to control their behavior and ensure their adherence to treatment regimens. This chapter explores how local health authorities ensure that HIV-positive clients behave in a manner officials deem responsible—and how they catch and punish those who do not. While the state maintains that the work of local health officials is done solely in the interests of promoting public health, their efforts to control HIV-positive clients reveal that they are also engaged in policing and law enforcement.

Hunting HIV-Positive Women in Greece as Parasites

2016 ◽  
pp. 779-788
Author(s):  
Pitsou Anastasia
Keyword(s):  
Public Health ◽  
Social Media ◽  
Public Policies ◽  
Personal Data ◽  
Hiv Positive ◽  
Hiv Positive Women ◽  
The Social

In this chapter, the authors discuss public policies of stigmatization and fascitization. In Greece, HIV-positive women have been imprisoned while their personal data have been published in newspapers and the social media aiming to inform citizens and to protect public health.

scholarly journals Electronic data sharing between public health department and clinical providers improves accuracy of HIV retention data

2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S421-S422
Author(s):  
Jessica P Ridgway ◽  
Jessica Schmitt ◽  
Ellen Almirol ◽  
Monique Millington ◽  
Erika Harding ◽  
...  
Keyword(s):  
Public Health ◽  
Data Sharing ◽  
Retention In Care ◽  
Health Department ◽  
Birth Date ◽  
Hiv Positive ◽  
Public Health Department ◽  
Grant Recipient ◽  
Lost To Follow Up

Abstract Background Retention in care is critical for treatment and prevention of HIV. Many HIV care clinics measure retention rate, but data are often incomplete for patients who are classified as lost to follow-up but may be actually in care elsewhere, moved, or died. The Data to Care (D2C) initiative supports data sharing between health departments and HIV providers to confirm patient care status and facilitate reengagement efforts for out of care HIV patients. Methods The University of Chicago Medicine (UCM) provided an electronic list to the Chicago Department of Public Health (CDPH) of adult HIV-positive patients whose retention status was not certain. Retention in care was defined as at least 2 visits >90 days apart within the prior 12 months. CDPH matched this list of patients with data from the Chicago electronic HIV surveillance database. Matches were based on patient name, including alternative spellings and phonetics, and birth date. CDPH also cross-checked patient names with the CDC’s national enhanced HIV-AIDS Reporting System (eHARS) database. CDPH provided UCM with patient current care status, i.e., patient was in care elsewhere (as verified by lab data), moved out of state, or deceased. Results 780 HIV-positive patients received care in the UCM adult HIV clinic from January 1, 2013 to March 31, 2017. Of these, 360 were retained in care as of March 2017. We shared data with CDPH for 492 patients. Of these, 294 (59.8%) were matched, and 168 (34.1%) had a date of last medical care provided. See Table 1 for patient dispositions, before and after data sharing. 24 (13.4%) of patients believed to be lost to follow up according to UCM records were confirmed either transferred care or deceased according to health department data. Conclusion Data sharing between the health department and HIV providers can improve data accuracy regarding retention in care among people living with HIV. Disclosures J. P. Ridgway, Gilead FOCUS: Grant Investigator, Grant recipient; D. Pitrak, Gilead Sciences FOCUS: Grant Investigator, Grant recipient

scholarly journals On the Home Front: Specialized Reference Testing for Dengue in the Australasian Region

2018 ◽  
Vol 3 (3) ◽  
pp. 75 ◽  
Author(s):  
Alyssa T. Pyke ◽  
Wendy Gunn ◽  
Carmel Taylor ◽  
Ian Mackay ◽  
Jamie McMahon ◽  
...  
Keyword(s):  
Public Health ◽  
Disease Surveillance ◽  
Environmental Science ◽  
New Technologies ◽  
Home Front ◽  
Emerging Pathogens ◽  
Critical Elements ◽  
Department Of Health ◽  
Consultation Services ◽  
Australasian Region

Reference laboratories are vital for disease control and interpreting the complexities and impact of emerging pathogens. The role of these centralized facilities extends beyond routine screening capabilities to provide rapid, specific, and accurate diagnoses, advanced data analysis, consultation services, and sophisticated disease surveillance and monitoring. Within the Australasian region, the Public Health Virology Laboratory (PHV), Forensic and Scientific Services, Department of Health, Queensland Government, Australia, and the Institute of Environmental Science and Research Limited (ESR), New Zealand (NZ) perform specialized reference testing and surveillance for dengue viruses (DENVs) and other emerging arthropod-borne viruses (arboviruses), including chikungunya virus (CHIKV) and Zika virus (ZIKV). With a focus on DENV, we review the reference testing performed by PHV (2005 to 2017) and ESR (2008 to 2017). We also describe how the evolution and expansion of reference-based methodologies and the adoption of new technologies have provided the critical elements of preparedness and early detection that complement frontline public health control efforts and limit the spread of arboviruses within Australasia.

scholarly journals The early scientific literature response to the novel Coronavirus outbreak: who published what?

2020 ◽  
Author(s):  
Davide Gori ◽  
Erik Boetto ◽  
Maria Pia Fantini
Keyword(s):  
Public Health ◽  
Scientific Literature ◽  
Health Concern ◽  
Primary Data ◽  
The Novel ◽  
Epidemic Outbreak ◽  
Emerging Pathogens ◽  
Pubmed Database ◽  
Novel Coronavirus ◽  
Reported Data

AbstractIntroductionRecent events highlight how emerging and re-emerging pathogens are becoming global challenges for public health. In December 2019, a novel coronavirus has emerged. This has suddenly turned out into global health concern.ObjectivesAim of this research is to focus on the bibliometric aspects in order to measure what is published in the first 30-days of a global epidemic outbreakMethodsWe searched PubMed database in order to find all relevant studies in the first 30-days from the first publication.ResultsFrom the initial 442 identified articles, 234 were read in-extenso. The majority of papers come from China, UK and USA. 63.7% of the papers were commentaries, editorials and reported data and only 17.5% of the sources used data directly collected on the field. Topics mainly addressed were “epidemiology”, “preparedness” and “generic discussion”. NNR showed a reduction for both the objectives assessed from January to February.Conclusions“Diagnosis” and effective preventive and therapeutic measures were the fields in which more research is still needed. The vast majority of scientific literature in the first 30-days of an epidemic outbreak is based on reported data rather than primary data. Nevertheless, the scientific statements and public health decisions rely on these data.Strengths of our studyThis is the first bibliometric research in Pubmed Database on the first 30 days of publications regarding the novel Coronavirus (SARS-nCoV-2) outbreak of 2019.The vast majority of publication in the first 30-days of an epidemic outbreak are reported data or comments, and only a small fraction of the papers have directly collected data.Limitations of our studyOur research is only PubMed based. It ill be auspicable to consult more than one relevant database in future papers.In addition, we excluded non-English publications leading to a potential bias due to the fact that the outbreak started in China.

scholarly journals Epidemiological studies of malaria parasite on HIV patients attending General Hospital Awo-Omamma, Oru East, Imo State,Nigeria

2020 ◽  
Vol 2 (7A) ◽  
Author(s):  
Treasure Njoku-Obi
Keyword(s):  
Public Health ◽  
Viral Load ◽  
Epidemiological Studies ◽  
Hiv Positive ◽  
Age Group ◽  
Hiv Patients ◽  
Imo State ◽  
Malarial Infection ◽  
High Prevalence ◽  
The World

HIV and malaria are the two most prevalent and deadly diseases in the world. Malaria and HIV accounted for about 255 million cases in 2017, with malaria having 86% of this distribution and HIV having 14% of the distribution. Given the overlap of their geographic distribution and resultant rates of coinfection, interactions between the two diseases pose major public health problems. This study was aimed at investigating the epidemiology of malaria –HIV co-infection in respect to sex, age and its association with CD4+ count and viral load. 230 HIV sero-positive participants and 100 HIV sero-negative participants(control) were employed for this study. 52 (22.6%) of the HIV infected participants tested positive for malaria while only 9(9.0%) of the non-HIV participants tested positive to malaria. The prevalence of malarial infection in HIV positive individuals was higher in females (23.9%) than in males (18.5%). While in age group of 30-39 showed the highest prevalence (35.3%) of co-infection. A high prevalence of 47.7% was recorded with CD4+ below 200 cells/μl than 7.6% in participants with CD4+ greater than 200 cells/μl. A highprevalence (49.2%) was also detected in patients with viral load of above 10,000 copies/μl compared to that of those with viral load less than 10,000 copies/μl(12.6%). This study showed a high prevalence of malaria in HIV patients in Awo-Omamma,Oru East, Imo state. This should be considered a great concern to public health. Thus, more effort should be put in research to curb this health issue.

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