Syntheses and structures of highly hindered N-functionalised alkyl and amido group 12 complexes MR2 (M=Zn, Cd, and Hg), [MRCl]2 (M=Zn and Hg)

2004 ◽  
Vol 689 (11) ◽  
pp. 1991-1999 ◽  
Author(s):  
Tania R van den Ancker ◽  
Lutz M Engelhardt ◽  
Mark J Henderson ◽  
Geraldine E Jacobsen ◽  
Colin L Raston ◽  
...  
Keyword(s):  
Author(s):  
L. Yu. Orekhova ◽  
A. A. Petrov ◽  
E. S. Loboda ◽  
I. V. Berezkina ◽  
K. V. Shadrina

Relevance. The study of age-related features of microcirculation in periodontal tissues, using non-invasive functional research methods, allows us to develop the optimal range of therapeutic measures, as well as form a “personalized therapeutic case”.Purpose. Study of the functional state of the microvasculature in the tissues of the parodont in individuals of various age groups.Materials and methods. A standard dental examination of 80 patients was carried out, the sample of participants was ranked in 4 groups by age: 1 group – 12 years old, 2 group – 15 years old, 3 group – from 16 to 18 years old, 4 group – from 22 to 24 years old. Hygiene and periodontal indices were determined for all patients, such as papillarymarginal-alveolar (PMA) in the Parma modification, the Mulleman bleeding index in the Cowell modification (SBI), and the simplified Green Vermillion index of oral hygiene (OHI–s), caries intensity indicators for a permanent bite (CPI), as well as ultrasound dopplerography of periodontal tissues using the apparatus "Minimax-Doppler-K".Results. When studying microcirculation in periodontal tissues, distinctive characteristics of linear (Vas) and volumetric (Qas) blood flow rates, as well as indicators of pulsation indices (PI) and peripheral resistance (RI) in people of different age groups were recorded.Conclusions. This study confirms the presence of various hemodynamic indicators of periodontal tissues in the studied groups, which is due to structural features of the circulatory system in age periods.


2018 ◽  
Vol 28 (2) ◽  
pp. 709-716
Author(s):  
Slavica Ostojić Krsmanović ◽  
Ljiljana Crnčević Radović

The modern way of life means a quick pace that carries a tremendous amount of stress, irregular diet and lack of physical activity, which poses a health risk. For this reason, the World Health Organization recommends physical activity of at least 30 minutes a day which can be, among others, achieved using the pool. Only safe swimming pool water can provide users with all the benefits of its use, which will lead to overall health improvement. Although microbiological hazards pose the greatest danger to the health, chemical risks, as a result of unhygienic user behavior, should not be neglected since they can lead to a reduced effect of disinfection. The presence of urine in the pool water leads to a chemical reaction between nitrogen compounds from the urine and chlorine-based disinfectant, which creates chloramines which are the prerequisite for the occurrence of by-products of disinfection. As a result of their presence, the pool users may experience irritation of respiratory tract, skin and eyes. Our study was designed to determine the presence of urination during the use of the pool and examine the regularity of using the toilet before entering the pool. The survey was conducted on 1,506 respondents, divided into two age groups. In the age group of 12 to 15 years there were 380 respondents and in the age group of 18 to 25 years, 1,126 participants. Data of our study show that 27.0% of respondents had at least one episode of urination inside the pool. At least one episode of urination inside the pool had nearly one third of respondents aged 12 to 15 years (30.2%) and every fourth respondent in age group 18 to 25 years (25.9%). Of the total number of respondents in our research, 59.5% considered that the use of the toilet before entering the pool is very important hygienic measure. Hygienic significance of this measure identified 41.5% of the respondents in age group 12 to 15 years and 65.7% of respondents aged 18 to 25 years. In relation to the regularity of use, the results of our survey show that 50.5% of respondents, or half of our respondents, regularly use the toilet before entering the pool. In the age group 12 to 15 years hygienic measure regularly applied 35.7% of respondents. A significantly higher percentage of regular use of this hygienic measure, but still not sufficiently high, was recorded in the age group of 18 to 25 years (55.5%). The results of our study lead to conclusion that urination inside the pool is present as a form of unhygienic behavior of pool users, which represents a public health problem. Since the younger age group, from 12 to 15 years, showed a higher degree of risk-taking behavior, fundamental and continuous education on the importance of implementation of hygiene measures when using the pool is necessary. Code of conduct in the context of sports facilities, which include the swimming pools, should start since an early age. Learning about forms of behavior in public places and public sports facilities begins in the family and later continues throughout schooling. Health education is a part of the general culture of every individual, regardless of gender, age, education and standard.


2019 ◽  
Vol 90 (1) ◽  
pp. 3-12 ◽  
Author(s):  
Masahiro Seiryu ◽  
Hiroto Ida ◽  
Atsushi Mayama ◽  
Satoshi Sasaki ◽  
Shutaro Sasaki ◽  
...  

ABSTRACT Objectives To investigate the hypothesis that there is difference in the treatment outcomes of milder skeletal Class III malocclusion between facemask and facemask in combination with a miniscrew in growing patients. Materials and Methods Patients were randomly divided into two groups. In one group, the patients were treated with facemask therapy (FM group: 12 males, eight females, average age: 10 years, 5 months ± 1 year, 8 months). In the other group, patients were treated with facemask therapy along with a miniscrew (FM+MS group: 12 males, seven females, average age: 11 years, 1 month ± 1 year, 3 months). A lingual arch with hooks was fixed to the maxillary arch in both groups and a protractive force of 500 g was applied from the facemask to the hooks. The patients were instructed to use the facemask for 12 hours per day. In the FM+MS group, a miniscrew was inserted into the palate and fixed to the lingual arch. Results Mobility and loosening of the miniscrew were not observed during treatment. Lateral cephalometric analysis showed that SNA, SN-ANS, and ANB values were significantly increased in the FM+MS group compared with those for the FM group (SNA, 1.1° SN-ANS, 1.3° ANB, 0.8°). Increase in proclination of maxillary incisors was significantly greater in the FM group than in the FM+MS group (U1-SN, 5.0°). Conclusions During treatment of milder skeletal Class III malocclusion, facemask therapy along with a miniscrew exhibits fewer negative side effects and delivers orthopedic forces more efficiently to the maxillary complex than facemask therapy alone.


Molecules ◽  
2021 ◽  
Vol 26 (6) ◽  
pp. 1739
Author(s):  
Artyom A. Astafiev ◽  
Olga V. Repina ◽  
Boris S. Tupertsev ◽  
Alexey A. Nazarov ◽  
Maria R. Gonchar ◽  
...  

Arylazoimidazoles are important dyes which were intensively studied in the past. In contrast, triarylazoimidazoles (derivatives which carry aryl substituents at the imidazole core) received almost no attention in the scientific literature. Here, we report a new family of simple and easily accessible triarylazoimidazole-group 12 metal complexes, which feature highly efficient photo-luminescence emission (Φ up to  0.44). Novel compounds exhibit bright red emission in solution, which could be excited with a visible light.


Author(s):  
Annemieke Maria Pustjens ◽  
Jacqueline Jozefine Maria Castenmiller ◽  
Jan Dirk te Biesebeek ◽  
Polly Ester Boon

Abstract Purpose This study attempted gaining insight into the intake of protein and fat of 12- to 36-month-old children in the Netherlands. Methods In 2017, a Total Diet Study (TDS) was carried out in the Netherlands including following three age groups: 12–17-, 18–23- and 24- to 36-month-old children. Protein and fat concentrations of 164 composite samples were analysed and combined with the consumption data from the Dutch National Food Consumption Survey 2012–2016 (DNFCS). Results Median protein intake of the 12- to 35-month-old Dutch children based on the TDS was 35 g/day with main contributions from the food subgroups “milk and milk-based beverages”, “beef” and “yoghurts and desserts”. Median fat intake was 34 g/day with main contributions from the food subgroups “margarines”, “cheeses” and “milk and milk-based beverages”. For the youngest age group (12- to 18-month-old children), (ready to drink) follow-on formula was one of the main contributors to the fat intake. Conclusion Compared to the EFSA reference values, protein intake of the Dutch 12- to 36-month-old children is high, whereas fat intake follows the reference intake. A TDS is a suitable instrument to estimate macronutrient intakes.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Christina D. Moon ◽  
Luis Carvalho ◽  
Michelle R. Kirk ◽  
Alan F. McCulloch ◽  
Sandra Kittelmann ◽  
...  

AbstractAnthelmintic treatment of adult ewes is widely practiced to remove parasite burdens in the expectation of increased ruminant productivity. However, the broad activity spectra of many anthelmintic compounds raises the possibility of impacts on the rumen microbiota. To investigate this, 300 grazing ewes were allocated to treatment groups that included a 100-day controlled release capsule (CRC) containing albendazole and abamectin, a long-acting moxidectin injection (LAI), and a non-treated control group (CON). Rumen bacterial, archaeal and protozoal communities at day 0 were analysed to identify 36 sheep per treatment with similar starting compositions. Microbiota profiles, including those for the rumen fungi, were then generated for the selected sheep at days 0, 35 and 77. The CRC treatment significantly impacted the archaeal community, and was associated with increased relative abundances of Methanobrevibacter ruminantium, Methanosphaera sp. ISO3-F5, and Methanomassiliicoccaceae Group 12 sp. ISO4-H5 compared to the control group. In contrast, the LAI treatment increased the relative abundances of members of the Veillonellaceae and resulted in minor changes to the bacterial and fungal communities by day 77. Overall, the anthelmintic treatments resulted in few, but highly significant, changes to the rumen microbiota composition.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Yiqin Zhou ◽  
Haobo Li ◽  
Dong Xiang ◽  
Jiahua Shao ◽  
Qiwei Fu ◽  
...  

Abstract Introduction To evaluate the clinical efficacy of arthroscopic therapy with infrapatellar fat pad cell concentrates in treating knee cartilage lesions, we conducted a prospective randomized single-blind clinical study of controlled method. Methods Sixty cases from Shanghai Changzheng Hospital from April 2018 to December 2019 were chosen and randomly divided into 2 groups equally. Patients in the experiment group were treated through knee arthroscopy with knee infrapatellar fat pad cell concentrates containing mesenchymal stromal cells, while patients in the control group were treated through regular knee arthroscopic therapy. VAS and WOMAC scores were assessed at pre-operation, and 6 weeks, 12 weeks, 6 months, and 12 months after intervention. MORCART scores were assessed at pre-operation and 12 months after intervention. Results Twenty-nine cases in the experiment group and 28 cases in the control group were followed up. No significant difference in VAS, WOMAC, and MOCART scores were found between the two groups before surgery (P > 0.05). The WOMAC total and WOMAC function scores of the experiment group were significantly lower than those of the control group 6 months and 12 months after surgery (P < 0.05). The VAS rest and VAS motion scores of the experiment group were found significantly lower than those of the control group 12 months after surgery (P < 0.05). The MOCART scores of the experiment group were found significantly higher compared with the control group 12 months after surgery (P < 0.05). No significant difference in WOMAC stiffness scores were found between the two groups. Conclusions The short-term results of our study are encouraging and demonstrate that knee arthroscopy with infrapatellar fat pad cell concentrates containing mesenchymal stromal cells is safe and provides assistance in reducing pain and improving function in patients with knee cartilage lesions. Trial registration ChiCTR1800015379. Registered on 27 March 2018, http://www.chictr.org.cn/showproj.aspx?proj=25901.


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