Phosphonium surfactant stabilised silver nanoparticles. Correlation of surfactant structure with physical properties and biological activity of silver nanoparticles

Phosphorus-containing heterocyclic cationic surfactants alkyldimethylphenylphospholium bromides with the alkyl chain length 14 to 18 carbon atoms were used for the stabilization of silver nanodispersions. Zeta potential of silver nanodispersions ranges from +35 to +70 mV, which indicates the formation of stable silver nanoparticles (AgNPs). Long-chain heptadecyl and octadecyl homologs of the surfactants series provided the most intensive stabilizing effect to AgNPs, resulting in high positive zeta potential values and smaller diameter of AgNPs in the range 50–60 nm. A comparison with non-heterocyclic alkyltrimethylphosphonium surfactants of the same alkyl chain length showed better stability and more positive zeta potential values for silver nanodispersions stabilized with heterocyclic phospholium surfactants. Investigations of biological activity of phospholium-capped AgNPs are represented by the studies of antimicrobial activity and cytotoxicity. While cytotoxicity results revealed an increased level of HepG2 cell growth inhibition as compared with the cytotoxicity level of silver-free surfactant solutions, no enhanced antimicrobial action of phospholium-capped AgNPs against microbial pathogens was observed. The comparison of cytotoxicity of AgNPs stabilized with various non-heterocyclic ammonium and phosphonium surfactants shows that AgNPs capped with heterocyclic alkyldimethylphenylphospholium and non-heterocyclic triphenyl-substituted phosphonium surfactants have the highest cytotoxicity among silver nanodispersions stabilized by the series of ammonium and phosphonium surfactants.

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Comparison of Osmotic Resistance, Shape and Transmembrane Potential of Erythrocytes Collected from Healthy and Fed with High Fat-Carbohydrates Diet (HF-CD) Pigs—Protective Effect of Cistus incanus L. Extracts

Materials ◽

10.3390/ma14041050 ◽

2021 ◽

Vol 14 (4) ◽

pp. 1050

Author(s):

Sylwia Cyboran-Mikołajczyk ◽

Robert Pasławski ◽

Urszula Pasławska ◽

Kacper Nowak ◽

Michał Płóciennik ◽

...

Keyword(s):

Biological Activity ◽

Physical Properties ◽

Plasma Lipid ◽

Membrane Lipid ◽

Osmotic Resistance ◽

High Fat ◽

Atherosclerotic Lesions ◽

Cistus Incanus ◽

Osmotic Resistance Of Erythrocytes ◽

The Impact

Long-term high fat-carbohydrates diet (HF-CD) contributes to the formation of irreversible changes in the organism that lead to the emergence of civilization diseases. In this study, the impact of three-month high-fat diet on the physical properties of erythrocytes (RBCs) was studied. Furthermore, the biological activity of Cistus incanus L. extracts, plant known with high pro-health potential, in relation to normal and HF-CD RBCs, was determined. Obtained results have shown that, applied HF-CD modified shape, membrane potential and osmotic resistance of erythrocytes causing changes in membrane lipid composition and the distribution of lipids. The impact of HF-CD on physical properties of RBCs along with atherosclerotic lesions of the artery was visible, despite the lack of statistically significant changes in blood morphology and plasma lipid profile. This suggests that erythrocytes may be good markers of obesity-related diseases. The studies of biological activity of Cistus incanus L. extracts have demonstrated that they may ameliorate the effect of HF-CD on erythrocytes through the membrane-modifying and antioxidant activity.

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Physical properties, ligand substitution reactions, and biological activity of Co(iii)-Schiff base complexes

Dalton Transactions ◽

10.1039/c8dt04606a ◽

2019 ◽

Vol 48 (18) ◽

pp. 5987-6002 ◽

Cited By ~ 5

Author(s):

A. Paden King ◽

Hendryck A. Gellineau ◽

Samantha N. MacMillan ◽

Justin J. Wilson

Keyword(s):

Biological Activity ◽

Schiff Base ◽

Physical Properties ◽

Ligand Exchange ◽

Ligand Substitution ◽

Schiff Base Complexes ◽

Substitution Reactions ◽

Anticancer Properties ◽

Ligand Substitution Reactions

A subset of fluorinated Co(iii) Schiff base complexes was synthesized, and their structural, ligand exchange, and anticancer properties were investigated.

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Biosynthesis of Silver Nanoparticles by Punica Granatum Peel Extract and their Biological Activity on different Pathogenic Bacteria

NeuroQuantology ◽

10.14704/nq.2021.19.9.nq21135 ◽

2021 ◽

Vol 19 (9) ◽

pp. 38-45

Author(s):

Hussein H. Al-Turnachy ◽

Fadhilk. alibraheemi ◽

Ahmed Abd Alreda Madhloom ◽

Zahraa Yosif Motaweq ◽

Nibras Yahya Abdulla

Keyword(s):

Antimicrobial Activity ◽

Silver Nanoparticles ◽

Biological Activity ◽

Pathogenic Bacteria ◽

Punica Granatum ◽

Gram Positive ◽

Gram Negative ◽

Inhibition Zones ◽

Peel Extract

The present study was included the assessment of the antimicrobial activity of AgNPs synthesized by Punica granatum peel extract against pathogenic bacteria by testing warm aqueous P. granatum peel extract and silver nanoparticles. Punica granatum indicated potency for AgNP extracellular nanobiosynthesis after addition of silver nitrate (AgNO3) 4mM to the extract supernatant, in both concentrations (100mg and 50mg). The biogenic AgNPs showed potency to inhibit both gram-negative and gram-positive bacterial growth. Zons of inhibition in (mm) was lesser in gram-positive than gram-negative bacteria. The resulted phytogenic AgNPs gave higher biological activity than warm aqueous Punica granatum peel extract. The inhibition zone of the phytogenic AgNPs on E. coli reached 17.53, 22.35, and 26.06 mm at (0.1, 0.5, and 1) mg/ml respectively. While inhibition zones of Punica warm aqueous extract reached 5.33, 10.63, and 16.08 mm at the same concentrations. phytogenic AgNPs gave smaller inhibition zones in gram-positive than gram- negative. Cytotoxic activity of the phytogenic AgNPs was assayed in vitro agaist human blood erythrocytes (RBCs), spectroscopic results showed absorbance at 540 nm hemolysis was observed. In general, AgNPs showed least RBCs hemolysis percentage, at 1 mg/ml concentration, hemolysis percentage was (4.50%). This study, concluded that the Punica granatum peel extract has the power of synthses of AgNPs characterized by broad spectrum antimicrobial activity with cyto-toxicity proportional to AgNPs concentration.

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Green Synthesis of Silver Nanoparticles Using Ledebouria Revoluta Bulb Extractand Its Biological Activity

Proceedings of the International Conference on Nanomedicine (ICON-2019) - Springer Proceedings in Materials ◽

10.1007/978-3-030-25135-2_1 ◽

2019 ◽

pp. 1-10

Author(s):

R. Aswini ◽

S. Meimozhi ◽

R. Tamilmozhi ◽

M. Kowsalya ◽

S. Murugesan

Keyword(s):

Silver Nanoparticles ◽

Biological Activity ◽

Green Synthesis

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Biogenic silver nanoparticles based on trichoderma harzianum: synthesis, characterization, toxicity evaluation and biological activity

Scientific Reports ◽

10.1038/srep44421 ◽

2017 ◽

Vol 7 (1) ◽

Cited By ~ 48

Author(s):

Mariana Guilger ◽

Tatiane Pasquoto-Stigliani ◽

Natália Bilesky-Jose ◽

Renato Grillo ◽

P. C. Abhilash ◽

...

Keyword(s):

Silver Nanoparticles ◽

Biological Activity ◽

Trichoderma Harzianum ◽

Toxicity Evaluation ◽

Biogenic Silver Nanoparticles

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Biological Activity, Physical Properties, and Toxicity

International Journal of Quantitative Structure-Property Relationships ◽

10.4018/ijqspr.2021070102 ◽

2021 ◽

Vol 6 (3) ◽

pp. 25-34

Author(s):

Ranita Pal ◽

Pratim Kumar Chattaraj

Keyword(s):

Molecular Structure ◽

Biological Activity ◽

Molecular Biology ◽

Drug Design ◽

Physical Properties ◽

Quantitative Structure Activity Relationship ◽

Molecular Properties ◽

Quantitative Structure ◽

Qsar Analysis ◽

Structure Activity

In the current pandemic-stricken world, quantitative structure-activity relationship (QSAR) analysis has become a necessity in the domain of molecular biology and drug design, realizing that it helps estimate properties and activities of a compound, without actually having to spend time and resources to synthesize it in the laboratory. Correlating the molecular structure of a compound with its activity depends on the choice of the descriptors, which becomes a difficult and confusing task when we have so many to choose from. In this mini-review, the authors delineate the importance of very simple and easy to compute descriptors in estimating various molecular properties/toxicity.

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