scholarly journals Valid and powerful second-level group statistics for decoding accuracy: Information prevalence inference using the i-th order statistic (i-test)

NeuroImage ◽  
2021 ◽  
pp. 118456
Author(s):  
Satoshi Hirose
Keyword(s):  
Order Statistic ◽  
Decoding Accuracy ◽  
Level Group

scholarly journals Valid and powerful group statistics for decoding accuracy: Information Prevalence Inference using the i-th order statistic (i-test)

2019 ◽  
Author(s):  
Satoshi Hirose
Keyword(s):  
Order Statistic ◽  
Statistical Power ◽  
Null Distribution ◽  
Statistical Test ◽  
Cognitive Content ◽  
Population Inference ◽  
Decoding Accuracy ◽  
High Statistical Power ◽  
Level Group ◽  
Powerful Group

AbstractIn fMRI decoding studies using pattern classification, a “second-level” group statistical test is typically performed after “first-level” decoding analyses for individual participants. Neuroscientists often test the mean decoding accuracy across participants against the chance-level accuracy (e.g., one-sample Student t-test) to verify whether brain activation includes information about the label (i.e., cognitive content). However, Allefeld et al., (2016) notified that positive results for such tests only indicate that “there are some people in the population whose fMRI data carry information about the experimental condition.” Thus, such tests cannot provide inferences about the trend of the majority. They proposed an alternative method, in which prevalence inference is implemented. In this study, I extended their method and propose statistical test “information prevalence inference using the i-th order statistic (i-test)”. Compared with the method proposed in the previous study, i-test has high statistical power to provide an inference regarding major population trends. In i-test, the i-th lowest sample decoding accuracy (the i-th order statistic) is compared to the null distribution to test whether the proportion of the higher-than-chance decoding accuracy in the population (information prevalence) is higher than the threshold. Thus, a significant result of the i-test can be interpreted as “the majority of the population has information about the label in the brain.” Numerical calculation identified its high statistical power. Also, theoretical detail is provided, and the use of this method in an fMRI decoding study is demonstrated.Allefeld, C., Görgen, K., Haynes, J.D., 2016. Valid population inference for information-based imaging: From the second-level t-test to prevalence inference. Neuroimage.

Collective Efficacy and Organizational Commitment in an Italian City Hall

2009 ◽  
Vol 14 (4) ◽  
pp. 363-371 ◽  
Author(s):  
Laura Borgogni ◽  
Silvia Dello Russo ◽  
Laura Petitta ◽  
Gary P. Latham
Keyword(s):  
Organizational Commitment ◽  
Collective Efficacy ◽  
Structural Equation ◽  
Structural Equation Models ◽  
Practical Significance ◽  
City Hall ◽  
Italian City ◽  
Public Sector Managers ◽  
The Individual ◽  
Level Group

Employees (N = 170) of a City Hall in Italy were administered a questionnaire measuring collective efficacy (CE), perceptions of context (PoC), and organizational commitment (OC). Two facets of collective efficacy were identified, namely group and organizational. Structural equation models revealed that perceptions of top management display a stronger relationship with organizational collective efficacy, whereas employees’ perceptions of their colleagues and their direct superior are related to collective efficacy at the group level. Group collective efficacy had a stronger relationship with affective organizational commitment than did organizational collective efficacy. The theoretical significance of this study is in showing that CE is two-dimensional rather than unidimensional. The practical significance of this finding is that the PoC model provides a framework that public sector managers can use to increase the efficacy of the organization as a whole as well as the individual groups that compose it.

THE CLINICAL COURSE OF MYOCARDIAL INFARCTION PECULIARITIES IN MEN UNDER 60 YEARS OLD WITH PULMONARY HYPERTENSION

2020 ◽  
pp. 64-68
Author(s):  
Gordienko A.V. ◽  
Men’shikova A.N. ◽  
Sotnikov A.V.
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Pulmonary Hypertension ◽  
Clinical Course ◽  
Comparative Assessment ◽  
Study Group ◽  
Routine Examination ◽  
Group Iii ◽  
Appropriate Treatment ◽  
Level Group

Relevance. Pulmonary hypertension (PH) negatively affects the prognosis of myocardial infarction (MI). Aim. To evaluate MI clinical features (CF) in men under 60 years old (y.o.) with PH, arising during MI to improve pre-vention and outcomes. Material and methods. The study included men 19-60 y.o. with MI and various dynamics of mean pulmonary artery pressure (MPAP), determined by echocardiography (A. Kitabatake) in first 48 hours (1) and completion of third week (2). Patients were divided into four groups: studied (I) included 67 patients (mean age 50.4±7.1 y.o) with PH (MPAP2 25 and more mm Hg) and normal of MPAP1 level. Group II included patients with a normal MPAP in both phases of study (70; 52.1±6.6 y.o); group III – with elevated MPAP at both study points (149; 51.2±5.5 y.o) and IV – with in-creased MPAP1 and normal MPAP2 (61, 50.5±6.8 y.o). A comparative assessment of the MI CF frequency in selected groups were performed. Results. The study group occupied intermediate place frequency in medical history presence: coronary heart disease (I: 59.5; II: 61.4; III: 63.6 and IV: 48.9%; p = 0.04), chronic heart failure (CHF) (35.7 ; 34.1; 51.1 and 24.5%, respec-tively; p=0.001), repeated (45.2; 42.0; 47.3 and 29.8%) and early recurrent (3.6; 3.4 ; 6.0 and 3.2%; pIII-IV=0.006) MI, Q-MI (44.0; 35.2; 58.7 and 56.4; p=0.001), anginal MI phenotype (75.0; 74.7; 54.3 and 77.7%; p˂0.0001) and acute HF (ACF) (45,2; 36,8; 50,5 и 48,9%; р=0,002). No pulmonary edema was detected in it (p˂0.0001). Conclusions. Men under 60 y.o. with PH resulting from MI occupy an intermediate place in frequency of complica-tions, ACF and CHF in first 56 days of MI during routine examination compared with other MPAP dynamics patients. This confirms the need for additional verification of PH genesis for the appropriate treatment.

scholarly journals Cervical arthroplasty: what does the labeling say?

2017 ◽  
Vol 42 (2) ◽  
pp. E2 ◽  
Author(s):  
Mazda K. Turel ◽  
Mena G. Kerolus ◽  
Owoicho Adogwa ◽  
Vincent C. Traynelis
Keyword(s):  
Outcome Measures ◽  
Revision Surgery ◽  
Controlled Trial ◽  
Neck Disability Index ◽  
Specific Treatment ◽  
The United States ◽  
Cervical Disc ◽  
Cervical Arthroplasty ◽  
Single Level ◽  
Level Group

OBJECTIVE The aim of this paper was to comprehensively review each of the Food and Drug Administration (FDA)–approved labels of 7 total cervical disc replacements, assess the exact methodology in which the trial was conducted, and provide a broad comparison of these devices to allow each surgeon to determine which disc best suits his or her specific treatment goals based on the specific labels and not the studies published. METHODS The FDA-approved labels for each of the 7 artificial discs were obtained from the official FDA website. These labels were meticulously compared with regard to the statistical analysis performed, the safety and efficacy data, and the randomized controlled trial that each artificial disc was involved in to obtain the FDA approval for the product or device. Both single-level and 2-level approvals were examined, and primary and secondary end points were assessed. RESULTS In the single-level group, 4 of the 7 artificial discs—Prestige LP, Prestige ST, Bryan, and Secure-C—showed superiority in overall success. Prestige ST showed superiority in 3 of 4 outcome measures (neurological success, revision surgery, and overall success), while the other aforementioned discs showed superiority in 2 or fewer measures (Prestige LP, neurological and overall success; Bryan, Neck Disability Index [NDI] and overall success; Secure-C, revision surgery and overall success; Pro-Disc C, revision surgery). The PCM and Mobi-C discs demonstrated noninferiority across all outcome measures. In the 2-level group, Prestige LP and Mobi-C demonstrated superiority in 3 outcome measures (NDI, secondary surgery, and overall success) but not neurological success. CONCLUSIONS This paper provides a comprehensive analysis of 7 currently approved and distributed artificial discs in the United States. It compares specific outcome measures of these devices against those following the standard of care, which is anterior cervical discectomy and fusion. This information will provide surgeons the opportunity to easily answer patients' questions and remain knowledgeable when discussing devices with manufacturers.

scholarly journals Blur-readable two-dimensional barcode based on blur-invariant shape and geometric features

2021 ◽  
Vol 18 (2) ◽  
pp. 172988142199958
Author(s):  
Shundao Xie ◽  
Hong-Zhou Tan
Keyword(s):  
Circular Disk ◽  
Geometric Features ◽  
Two Dimensional ◽  
Common Solution ◽  
Ringing Artifacts ◽  
2D Barcode ◽  
Defocus Blur ◽  
Blurred Image ◽  
Decoding Accuracy ◽  
Invariant Shape

In recent years, the application of two-dimensional (2D) barcode is more and more extensive and has been used as landmarks for robots to detect and peruse the information. However, it is hard to obtain a sharp 2D barcode image because of the moving robot, and the common solution is to deblur the blurry image before decoding the barcode. Image deblurring is an ill-posed problem, where ringing artifacts are commonly presented in the deblurred image, which causes the increase of decoding time and the limited improvement of decoding accuracy. In this article, a novel approach is proposed using blur-invariant shape and geometric features to make a blur-readable (BR) 2D barcode, which can be directly decoded even when seriously blurred. The finder patterns of BR code consist of two concentric rings and five disjoint disks, whose centroids form two triangles. The outer edges of the concentric rings can be regarded as blur-invariant shapes, which enable BR code to be quickly located even in a blurred image. The inner angles of the triangle are of blur-invariant geometric features, which can be used to store the format information of BR code. When suffering from severe defocus blur, the BR code can not only reduce the decoding time by skipping the deblurring process but also improve the decoding accuracy. With the defocus blur described by circular disk point-spread function, simulation results verify the performance of blur-invariant shape and the performance of BR code under blurred image situation.

A Note on the Accuracy of Normal Approximation of Random Quantities

2021 ◽  
Vol 73 (1) ◽  
pp. 62-67
Author(s):  
Ibrahim A. Ahmad ◽  
A. R. Mugdadi
Keyword(s):  
Sample Size ◽  
Order Statistic ◽  
Normal Approximation ◽  
Order Approximation ◽  
Random Variables ◽  
Random Variable ◽  
Limiting Distribution ◽  
Exact Order ◽  
Fixed Sample ◽  
Independent Identically Distributed

For a sequence of independent, identically distributed random variable (iid rv's) [Formula: see text] and a sequence of integer-valued random variables [Formula: see text], define the random quantiles as [Formula: see text], where [Formula: see text] denote the largest integer less than or equal to [Formula: see text], and [Formula: see text] the [Formula: see text]th order statistic in a sample [Formula: see text] and [Formula: see text]. In this note, the limiting distribution and its exact order approximation are obtained for [Formula: see text]. The limiting distribution result we obtain extends the work of several including Wretman[Formula: see text]. The exact order of normal approximation generalizes the fixed sample size results of Reiss[Formula: see text]. AMS 2000 subject classification: 60F12; 60F05; 62G30.

scholarly journals High expression of hypoxia inducible factor 1α related with acquired resistant to EGFR tyrosine kinase inhibitors in NSCLC

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Qian Jin ◽  
Feihua Huang ◽  
Xianrong Xu ◽  
Haidong He ◽  
Yingqing Zhang
Keyword(s):  
First Generation ◽  
Kinase Inhibitors ◽  
Acquired Resistance ◽  
Hypoxia Inducible Factor ◽  
High Expression ◽  
Normal Lung ◽  
Nsclc Tissue ◽  
T790m Mutation ◽  
Level Group ◽  
Egfr Tkis

AbstractThe acquired resistance of the first generation epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) is a main factor leading to poor prognosis of non-small cell lung cancer (NSCLC), so we researched whether the high expression of hypoxia-inducible factor-1α (HIF-1α) in EGFR-TKIs sensitive NSCLC tissue tends to induce the acquired resistance. We detected the HIF-1α in normal lung tissue, EGFR-TKIs sensitive NSCLC tissue, the first generation EGFR-TKIs acquired resistant NSCLC tissue and acquired EGFR T790M mutation NSCLC tissue with the method of immunohistochemistry. Then, we compared the expression of HIF-1α in these tissues, and evaluate the effect of HIF-1α expression to the occurrence of acquired resistance. The expression of HIF-1α was much higher in the EGFR-TKIs sensitive NSCLC tissue than that in normal lung tissue. HIF-1α level became higher after the occurrence acquired resistance. There was negative correlation between HIF-1α level before receiving treatment and the time of acquired resistance occurring as well as the acquired EGFR T790M mutation occurring. As the treatment going on, EGFR-TKIs sensitivity rate of low HIF-1α level group was much higher than that of high level group. The high expression of HIF-1α related with the acquired resistance of the first generation EGFR-TKIs, and HIF-1α can be a biomarker to predict the early occurrence of acquired resistance.

scholarly journals Senior Consumer Motivations and Perceived Value of Robot Service Restaurants in Korea

2021 ◽  
Vol 13 (5) ◽  
pp. 2755
Author(s):  
Min-Kyu Kwak ◽  
JeungSun Lee ◽  
Seong-Soo Cha
Keyword(s):  
South Korea ◽  
Low Income ◽  
Structural Equation ◽  
Perceived Value ◽  
Reliability And Validity ◽  
Equation Modeling ◽  
Consumer Innovativeness ◽  
Face To Face ◽  
Perceived Values ◽  
Level Group

This research empirically tested a theoretical model by defining senior customers’ intentions to use robot service restaurants emerging in South Korea. Non-face-to-face services have become increasingly important for seniors. Therefore, restaurant marketers should cater to senior customers’ needs by sustaining robot service restaurants. The study analyzed 243 questionnaires to verify the reliability and validity of the measurement items. The research hypotheses were examined using structural equation modeling (SEM). The suggested model comprised three stages: motivated consumer innovativeness (MCI), perceived value, and planned behavior (attitude, intention to use). The results revealed that senior customers’ perceived values positively influenced attitude and were enhanced by hedonically MCI (hMCI) and socially MCI. Moreover, the hedonic and social elements of motivation improved the attitude and usage intentions of robot service restaurants for senior customers. However, these relationships differed in terms of the income level of the customer groups. For the low-income senior-level group, hMCI was more influential on the perceived value. This study is meaningful because it analyzes the effect of MCI of seniors on the perceived value of robot service restaurants, which are growing rapidly in South Korea. It has empirically proved the moderating effect of different income groups, providing practical implications.

Sign in / Sign up

Export Citation Format

Share Document