scholarly journals Development of a silicon bulk radiation damage model for Sentaurus TCAD

Author(s):  
Å. Folkestad ◽  
K. Akiba ◽  
M. van Beuzekom ◽  
E. Buchanan ◽  
P. Collins ◽  
...  
Cells ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 42
Author(s):  
Xiaoyu Pu ◽  
Siyang Ma ◽  
Yan Gao ◽  
Tiankai Xu ◽  
Pengyu Chang ◽  
...  

Radiation-induced damage is a common occurrence in cancer patients who undergo radiotherapy. In this setting, radiation-induced damage can be refractory because the regeneration responses of injured tissues or organs are not well stimulated. Mesenchymal stem cells have become ideal candidates for managing radiation-induced damage. Moreover, accumulating evidence suggests that exosomes derived from mesenchymal stem cells have a similar effect on repairing tissue damage mainly because these exosomes carry various bioactive substances, such as miRNAs, proteins and lipids, which can affect immunomodulation, angiogenesis, and cell survival and proliferation. Although the mechanisms by which mesenchymal stem cell-derived exosomes repair radiation damage have not been fully elucidated, we intend to translate their biological features into a radiation damage model and aim to provide new insight into the management of radiation damage.


2020 ◽  
Vol 15 (01) ◽  
pp. C01029-C01029
Author(s):  
A. Morozzi ◽  
F. Moscatelli ◽  
G. Lombardi ◽  
G.M. Bilei ◽  
V. Hinger ◽  
...  

1997 ◽  
Vol 12 (7) ◽  
pp. 1766-1770 ◽  
Author(s):  
Ning Yu ◽  
Ram Devanathan ◽  
Kurt E. Sickafus ◽  
Michael Nastasi

Ion-irradiation was observed to transform MgAl2O4 spinel first to a metastable crystalline phase and then to an amorphous phase at cryogenic temperatures. Elastic stiffening of 15% occurred upon formation of the metastable crystalline phase. A second transformation from the metastable crystalline spinel to an amorphous state was accompanied by elastic softening of 25% relative to unirradiated spinel. This phase transformation behavior in spinel appears to be different from that in intermetallic compounds where only elastic softening associated with radiation damage accumulation is observed. A two-stage radiation damage model is proposed to explain the observed phase transformations.


Author(s):  
M. Isaacson ◽  
M.L. Collins ◽  
M. Listvan

Over the past five years it has become evident that radiation damage provides the fundamental limit to the study of blomolecular structure by electron microscopy. In some special cases structural determinations at very low doses can be achieved through superposition techniques to study periodic (Unwin & Henderson, 1975) and nonperiodic (Saxton & Frank, 1977) specimens. In addition, protection methods such as glucose embedding (Unwin & Henderson, 1975) and maintenance of specimen hydration at low temperatures (Taylor & Glaeser, 1976) have also shown promise. Despite these successes, the basic nature of radiation damage in the electron microscope is far from clear. In general we cannot predict exactly how different structures will behave during electron Irradiation at high dose rates. Moreover, with the rapid rise of analytical electron microscopy over the last few years, nvicroscopists are becoming concerned with questions of compositional as well as structural integrity. It is important to measure changes in elemental composition arising from atom migration in or loss from the specimen as a result of electron bombardment.


Author(s):  
T. E. Mitchell ◽  
M. R. Pascucci ◽  
R. A. Youngman

1. Introduction. Studies of radiation damage in ceramics are of interest not only from a fundamental point of view but also because it is important to understand the behavior of ceramics in various practical radiation enyironments- fission and fusion reactors, nuclear waste storage media, ion-implantation devices, outer space, etc. A great deal of work has been done on the spectroscopy of point defects and small defect clusters in ceramics, but relatively little has been performed on defect agglomeration using transmission electron microscopy (TEM) in the same kind of detail that has been so successful in metals. This article will assess our present understanding of radiation damage in ceramics with illustrations using results obtained from the authors' work.


Author(s):  
L. Reimer

Most information about a specimen is obtained by elastic scattering of electrons, but one cannot avoid inelastic scattering and therefore radiation damage by ionisation as a primary process of damage. This damage is a dose effect, being proportional to the product of lectron current density j and the irradiation time t in Coul.cm−2 as long as there is a negligible heating of the specimen.Therefore one has to determine the dose needed to produce secondary damage processes, which can be measured quantitatively by a chemical or physical effect in the thin specimen. The survival of micro-organisms or the decrease of photoconductivity and cathodoluminescence are such effects needing very small doses (see table).


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