scholarly journals Job-related factors associated with changes in sleep quality among healthcare workers screening for 2019 novel coronavirus infection: a longitudinal study

2020 ◽  
Vol 75 ◽  
pp. 21-26
Author(s):  
Xiaolong Zhao ◽  
Tong Zhang ◽  
Bin Li ◽  
Xiaoxu Yu ◽  
Zhiyue Ma ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Sleep Quality ◽  
Healthcare Workers ◽  
Related Factors ◽  
Factors Associated ◽  
Coronavirus Infection ◽  
Novel Coronavirus

scholarly journals A mixed-methods study of risk factors and experiences of healthcare workers tested for the novel coronavirus in Canada

2021 ◽  
Author(s):  
Arnold Ikedichi Okpani ◽  
Stephen Barker ◽  
Karen Lockhart ◽  
Jennifer Grant ◽  
Jorge Andrés Delgado-Ron ◽  
...  
Keyword(s):  
Healthcare Workers ◽  
Conditional Logistic Regression ◽  
Free Text ◽  
Prevention Measures ◽  
Related Factors ◽  
Licensed Practical Nurses ◽  
Work Related ◽  
Community Exposure ◽  
Using Data ◽  
Novel Coronavirus

ObjectivesWe aimed to investigate the contribution of occupational and non-work-related factors to the risk of novel coronavirus (SARS-CoV-2) infection among healthcare workers (HCWs) in Vancouver Coastal Health, British Columbia, Canada. We also aimed to examine how HCWs described their experiences.MethodsWe conducted a matched case-control study using data from online and phone questionnaires with optional open-ended questions completed by HCWs who sought SARS-CoV-2 testing between March 2020 and March 2021. Conditional logistic regression and thematic analysis were utilized.ResultsData from 1340 HCWs were included. Free-text responses were provided by 257 respondents. Adjusting for age, gender, race, occupation, and number of weeks since pandemic was declared, community exposure to a known COVID-19 case (adjusted odds ratio -aOR: 2.45; 95% CI 1.67-3.59), and difficulty accessing personal protective equipment -PPE- (aOR: 1.84; 95% CI 1.07-3.17) were associated with higher infection odds. Care-aides/licensed practical nurses had substantially higher risk (aOR: 2.92; 95% CI 1.49-5.70) than medical staff who had the lowest risk. Direct COVID-19 patient care was not associated with elevated risk. HCWs’ experiences reflected the phase of the pandemic when they were tested. Suboptimal communication, mental stress, and situations perceived as unsafe were common sources of dissatisfaction.ConclusionsCommunity exposures and occupation were important determinants of infection among HCWs in our study. The availability of PPE and clear communication enhanced a sense of safety. Varying levels of risk between occupational groups call for wider targeting of infection prevention measures. Strategies for mitigating community exposure and supporting HCW resilience are required.

scholarly journals Prevalence of poor psychiatric status and sleep quality among frontline healthcare workers during and after the COVID-19 outbreak: a longitudinal study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yifang Zhou ◽  
Hailong Ding ◽  
Yifan Zhang ◽  
Baoyan Zhang ◽  
Yingrui Guo ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Healthcare Workers ◽  
Multiple Logistic Regression Analysis ◽  
Liaoning Province ◽  
Poor Sleep ◽  
Poor Sleep Quality ◽  
Psychiatric Status ◽  
Novel Coronavirus ◽  
Frontline Healthcare Workers

AbstractPoor psychiatric status and sleep quality were common among frontline healthcare workers (FHWs) during the outbreak of the 2019 novel coronavirus disease (COVID-19), but the change in these mental health outcomes overtime remained unknown. This study compared the psychiatric status and sleep quality of FHWs during and after the COVID-19 outbreak in China. FHWs who volunteered to work in Hubei province (the COVID-19 epicenter) were assessed at baseline during the COVID-19 outbreak and re-assessed when they returned to their place of origin (Liaoning province) after the COVID-19 outbreak. Participants’ psychiatric status and sleep quality were measured with the Symptom CheckList-90 (SCL-90) and the Pittsburgh Sleep Quality Index (PSQI), respectively. A total of 494 FHWs was assessed at baseline and 462 at follow-up assessments. The prevalence of poor psychiatric status was 10.5% at baseline and increased to 14.9% at the follow-up assessment (P = 0.04). The corresponding figures of poor sleep quality at baseline and follow-up assessment were 16.4% and 27.9%, respectively (P < 0.001). Multiple logistic regression analysis found that severe fatigue (p = 0.003, OR = 1.266, 95% CI = 1.081–1.483), poor sleep quality (p < 0.001, OR = 1.283, 95% CI = 1.171–1.405), and history of pre-existing psychiatric disorders (p < 0.001, OR = 5.085, 95% CI = 2.144–12.06) were independently associated with higher odds of poor psychiatric status among the FHWs. Poor psychiatric status and sleep quality were common among FHWs during the COVID-19 outbreak, and the prevalence increased following their volunteer experiences. This suggests a critical need for longer-term psychological support for this subpopulation.

The opportunity of dipyridamole using for nonspecific primary prophylaxis against the COVID-19 infection in healthcare staff

2020 ◽  
Author(s):  
И.В. Куртов ◽  
Ю.О. Берман ◽  
Н.А. Никулина ◽  
Ю.В. Кузнецова ◽  
И.Л. Давыдкин
Keyword(s):  
High Risk ◽  
Interstitial Pneumonia ◽  
Healthcare Workers ◽  
Comparison Group ◽  
Primary Prophylaxis ◽  
The Novel ◽  
Healthcare Staff ◽  
Staff Members ◽  
Coronavirus Infection ◽  
Novel Coronavirus

Введение. Новая коронавирусная инфекция COVID-19 представляет повышенную опасность инфицирования у медицинских работников. Цель исследования: показать возможность применения дипиридамола у медицинских работников в комплексе мер первичной профилактики новой коронавирусной инфекции COVID-19. Материалы и методы. Наблюдались 33 медицинских работника: 14 человек принимали дипиридамол в дополнение к стандартным методам профилактики; 19 человек, не принимавшие дипиридамол, составили группу сравнения. Результаты. Несмотря на стандартные методы профилактики в многопрофильном стационаре, из 14 сотрудников, принимавших дипиридамол, 5 (35,7%) заболели коронавирусной инфекцией COVID-19 (подтвержденной); интерстициальная пневмония диагностирована у 4 человек. В группе из 19 сотрудников, не принимавших дипиридамол, заболели 13 (68,4%); интерстициальная пневмония была диагностирована у 11 человек. Заключение. Показана возможность применения дипиридамола в качестве дополнительного средства для снижения риска инфицирования новой коронавирусной инфекцией COVID-19. Background. Healthcare workers are under high risk of the novel coronavirus infection COVID-19. Objectives: to show the opportunity of dipyridamole using within the set of primary prophylaxis measures against the infection of COVID-19. Patients / Methods. We followed up 33 people from medical staff, of them 14 were taking dipyridamole in addition to standard prophylaxis methods; the comparison group consisted of 19 people who did not take dipyridamole. Results. Despite standard prophylaxis in a multidisciplinary hospital, out of 14 staff members who took dipyridamole, 5 (35.7%) catch coronavirus infection COVID-19 (justified); interstitial pneumonia was diagnosed in 4 people. In a group of 19 employees who did not take dipyridamole, 13 (68.4%) fell ill; interstitial pneumonia was diagnosed in 11 people. Conclusions. The opportunity of dipyridamole using has been shown as an additional means to reduce the risk to infect with COVID-19.

scholarly journals Novel coronavirus seropositivity and related factors among healthcare workers at a university hospital during the prevaccination period: a cross-sectional study

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Aziz Ogutlu ◽  
Oguz Karabay ◽  
Unal Erkorkmaz ◽  
Ertugrul Guclu ◽  
Seher Sen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Healthcare Workers ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Sectional Study ◽  
Related Factors ◽  
Cross Sectional ◽  
Antibody Positivity ◽  
Novel Coronavirus

Abstract Background This study aimed to investigate the specific risk factors for the transmission of novel coronavirus (SARS-CoV-2) among healthcare workers in different campuses of a university hospital and to reveal the risk factors for antibody positivity. Methods In this retrospective cross-sectional study, 2988 (82%) of 3620 healthcare workers in a university hospital participated. The coronavirus disease 2019 (COVID-19) antibody was investigated using serum from healthcare workers who underwent COVID-19 antibody testing. The antibody test results of the participants were evaluated based on their work campus, their profession and their workplace. The statistical significance level was p < 0.05 in all analyses. Results Of the participants in this study, 108 (3.6%) were antibody positive, and 2880 (96.4%) were negative. Antibody positivity rates were greater in nurses compared with other healthcare workers (p < 0.001). Regarding workplace, antibody positivity was greater in those working in intensive care compared to those working in other locations (p < 0.001). Conclusions Healthcare workers are at the highest risk of being infected with COVID-19. Those who have a higher risk of infection among healthcare workers and those working in high-risk areas should be vaccinated early and use personal protective equipment during the pandemic. Trial Registration: Retrospective permission was obtained from both the local ethics committee and the Turkish Ministry of Health for this study (IRB No:71522473/050.01.04/370, Date: 05.20.2020).

The use of interferon alpha-2b for prevention of novel coronavirus infection in healthcare workers

2021 ◽  
Vol 19 (2) ◽  
pp. 65-69
Author(s):  
Yu.O. Khlynina ◽  
◽  
A.A. Arova ◽  
A.B. Nevinsky ◽  
◽  
...  
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Tract ◽  
Interferon Alpha ◽  
Healthcare Workers ◽  
Distress Syndrome ◽  
Recombinant Interferon ◽  
Interferon Alpha 2B ◽  
Coronavirus Infection ◽  
Novel Coronavirus ◽  
Recombinant Interferon Alpha

Novel coronavirus infection (COVID-19) caused by SARS-CoV-2 has some specific clinical and immunopathogenic properties. SARS-CoV-2 is a single-stranded RNA virus that belongs to the Coronaviridae family, the Betacoronavirus genus. COVID-19 can be asymptomatic, the most common clinical manifestation of this disease is viral pneumonia. The development of acute respiratory distress syndrome is noted in less than 5% of cases. The entry gates of this virus are the epithelium of the upper respiratory tract and epithelial cells (epitheliocytes) of the gastrointestinal tract. When the virus enters the human respiratory tract, mucociliary clearance is inhibited and epithelial cells die, allowing the virus to enter the peripheral blood with subsequent damage to target organs (lungs, digestive tract, heart, kidneys). An important pathogenic characteristic of SARS-CoV-2 infection, especially with severe disease, is an excessive immune system response with massive release of cytokines, which causes acute respiratory distress syndrome. Clinical and experimental studies have shown that SARS-CoV-2 can be significantly more sensitive to type I interferons (IFN-I), than other coronaviruses. IFN-I deficiency is thought to play a key role in the pathogenesis of COVID-19, and several studies have shown that delayed IFN-I signaling is associated with sustained viral replication and serious complications. The use of interferon-based medicines (IFN-I) for the treatment and prevention of COVID-19 appears to be quite important to study attentively. This paper presents an original regimen of recombinant interferon alpha-2b-based medicine (Grippferon®, nasal drops and spray) for the medication-assisted post-exposure prevention of COVID-19 in healthcare specialists, working in the pediatric infectious disease hospital. The effectiveness and safety of this medication regimen for the COVID-19 prevention was shown. Key words: medication-assisted prevention, COVID-19, post-exposure protection of healthcare workers, recombinant interferon alpha-2b, Grippferon

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