Alcohol abuse and dependence before and after bariatric surgery: a review of the literature and report of a new data set

Introduction: Bariatric surgery results in both intentional and unintentional metabolic changes. In a high-volume bariatric center, extensive laboratory panels are used to monitor these changes pre- and postoperatively. Consecutive measurements of relevant biochemical markers allow exploration of the health state of bariatric patients and comparison of different patient groups. Objective: The objective of this study is to compare biomarker distributions over time between 2 common bariatric procedures, i.e., sleeve gastrectomy (SG) and gastric bypass (RYGB), using visual analytics. Methods: Both pre- and postsurgical (6, 12, and 24 months) data of all patients who underwent primary bariatric surgery were collected retrospectively. The distribution and evolution of different biochemical markers were compared before and after surgery using asymmetric beanplots in order to evaluate the effect of primary SG and RYGB. A beanplot is an alternative to the boxplot that allows an easy and thorough visual comparison of univariate data. Results: In total, 1,237 patients (659 SG and 578 RYGB) were included. The sleeve and bypass groups were comparable in terms of age and the prevalence of comorbidities. The mean presurgical BMI and the percentage of males were higher in the sleeve group. The effect of surgery on lowering of glycated hemoglobin was similar for both surgery types. After RYGB surgery, the decrease in the cholesterol concentration was larger than after SG. The enzymatic activity of aspartate aminotransferase, alanine aminotransferase, and alkaline phosphate in sleeve patients was higher presurgically but lower postsurgically compared to bypass values. Conclusions: Beanplots allow intuitive visualization of population distributions. Analysis of this large population-based data set using beanplots suggests comparable efficacies of both types of surgery in reducing diabetes. RYGB surgery reduced dyslipidemia more effectively than SG. The trend toward a larger decrease in liver enzyme activities following SG is a subject for further investigation.

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Prevalence of Alcohol Abuse Before and After Bariatric Surgery Associated With Nutritional and Lifestyle Factors: A Study Involving a Portuguese Population

Obesity Surgery ◽

10.1007/s11695-015-1609-7 ◽

2015 ◽

Vol 25 (9) ◽

pp. 1716-1722 ◽

Cited By ~ 10

Author(s):

Maria Goretti Pessoa de Araujo Burgos ◽

Poliana Coelho Cabral ◽

Regiane Maio ◽

Bruno M. P. M. Oliveira ◽

Margarida Sarmento Oliveira Dias ◽

...

Keyword(s):

Bariatric Surgery ◽

Alcohol Abuse ◽

Lifestyle Factors ◽

Portuguese Population ◽

Before And After

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POSTOPERATIVE COMPLIANCE OF BARIATRIC SURGERY PATIENTS REGARDING THE ASSESSMENT OF SERUM LEPTIN LEVELS AND INSULIN RESISTANCE

Medical Connections ◽

10.33311/medcon.2019.49.1.1 ◽

2019 ◽

Vol 49 (1/2019) ◽

Keyword(s):

Insulin Resistance ◽

Bariatric Surgery ◽

Serum Levels ◽

Medical Laboratory ◽

Leptin Resistance ◽

Obese Patients ◽

Laboratory Assessment ◽

Serum Leptin ◽

Before And After ◽

Bariatric Patients

Background and aims: Overweight and obese patients who undergo bariatric surgery require a rigorous clinical and paraclinical assessment both before and after the surgery at 3, 6, and 12 months.The present study aims the assessment of serum leptin levels and insulin resistance status in compliant bariatric patients to scheduled medical laboratory assessment at 6 months after surgery. Material and Method: The study included 109 eligible patients selected for bariatric surgery, 48 of whom attended the scheduled visit at 6 months after the surgery. Laboratory assessing regarded the insulin resistance by determining before meal the serum levels of leptin, glucose and insulin, as well as HOMA 1 and HOMA 2 indexes. Results: Patients who underwent bariatric treatment experienced a significant decrease in insulin resistance status. A higher percentage in the preoperative group was recorded in women, feature which was also recorded in the postoperative group that attended the scheduled visit at 6 months after surgery. Age is also an important factor that significantly influences the behavioral adherence to postoperative visits. Conclusions: Insulin resistance status improved significantly in 6 months after bariatric surgery among the fully compliant patients. The percentage of attendance at scheduled visits is higher among women, and decreases with age. Keywords: obesity surgery, leptin resistance, insulin resistance, HOMA index, compliance

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Vitamin D status before and after bariatric surgery during 4 years of follow-up

Endocrine Abstracts ◽

10.1530/endoabs.50.p340 ◽

2017 ◽

Author(s):

Alistair Fox ◽

Akheel Syed

Keyword(s):

Bariatric Surgery ◽

Vitamin D ◽

Vitamin D Status ◽

Before And After

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Dynamic Relationship between Crude Oil and Stock Prices in India: Before And After the Subprime Financial Crisis 2008

GIS Business ◽

10.26643/gis.v14i6.11683 ◽

2019 ◽

Vol 14 (6) ◽

pp. 96-104

Author(s):

P. Sakthivel ◽

S. Rajaswaminathan ◽

R. Renuka ◽

N. R.Vembu

Keyword(s):

Financial Crisis ◽

Crude Oil ◽

Stock Prices ◽

Oil Prices ◽

Energy Index ◽

Data Set ◽

Dynamic Relationship ◽

Crude Oil Prices ◽

Long Run ◽

Before And After

This paper empirically discovered the inter-linkages between stock and crude oil prices before and after the subprime financial crisis 2008 by using Johansan co-integration and Granger causality techniques to explore both long and short- run relationships. The whole data set of Nifty index, Nifty energy index, BSE Sensex, BSE energy index and oil prices are divided into two periods; before crisis (from February 15, 2005 to December31, 2007) and after crisis (from January 1, 2008 to December 31, 2018) are collected and analyzed. The results discovered that there is one-way causal relationship from crude oil prices to Nifty index, Nifty energy index, BSE Sensex and BSE energy index but not other way around in both periods. However, a bidirectional causality relationship between BSE Energy index and crude oil prices during post subprime financial crisis 2008. The co-integration results suggested that the absence of long run relationship between crude oil prices and market indices of BSE Sensex, BSE energy index, Nifty index and Nifty energy index before and after subprime financial crisis 2008.

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Pharmacokinetics and Pharmacodynamics of Oral Sertraline Before and After Bariatric Surgery

Case Medical Research ◽

10.31525/ct1-nct04147000 ◽

2019 ◽

Author(s):

Keyword(s):

Bariatric Surgery ◽

Pharmacokinetics And Pharmacodynamics ◽

Before And After

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Recent Advances in Treatment of Childhood Obesity

Current Drug Metabolism ◽

10.2174/1389200221666200817112311 ◽

2020 ◽

Vol 21 (14) ◽

pp. 1072-1078

Author(s):

Walter Milano ◽

Paola Ambrosio ◽

Francesca Carizzone ◽

Walter Di Munzio ◽

Valeria De Biasio ◽

...

Keyword(s):

Public Health ◽

Physical Activity ◽

Bariatric Surgery ◽

Childhood Obesity ◽

Treatment Strategies ◽

Lifestyle Changes ◽

Family Context ◽

Review Of The Literature ◽

Biological Factors ◽

The Family

: Childhood obesity has assumed epidemic proportions and is currently one of the most widespread public health problems. Many are the factors involved in the pathogenesis of excess weight with interactions between genetic, environmental and biological factors and therefore, also the therapeutic approach must be multidisciplinary and multidimensional. In this review of the literature, we report the contiguity of childhood obesity with eating disorders and the importance of involving the family context in order to induce stable lifestyle changes, both in relation to dietary and nutritional habits, but also in increasing physical activity. Finally, among the therapeutic options, although for selected cases, pharmacotherapy and bariatric surgery can be used as treatment strategies.

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Orosensory Perception of Fat/Sweet Stimuli and Appetite-Regulating Peptides before and after Sleeve Gastrectomy or Gastric Bypass in Adult Women with Obesity

Nutrients ◽

10.3390/nu13030878 ◽

2021 ◽

Vol 13 (3) ◽

pp. 878

Author(s):

Arnaud Bernard ◽

Johanne Le Beyec-Le Bihan ◽

Loredana Radoi ◽

Muriel Coupaye ◽

Ouidad Sami ◽

...

Keyword(s):

Bariatric Surgery ◽

Gastric Bypass ◽

Sleeve Gastrectomy ◽

Gut Hormones ◽

Sweet Taste ◽

Taste Perception ◽

Taste Sensitivity ◽

Adult Women ◽

Before And After ◽

The Impact

The aim of this study was to explore the impact of bariatric surgery on fat and sweet taste perceptions and to determine the possible correlations with gut appetite-regulating peptides and subjective food sensations. Women suffering from severe obesity (BMI > 35 kg/m2) were studied 2 weeks before and 6 months after a vertical sleeve gastrectomy (VSG, n = 32) or a Roux-en-Y gastric bypass (RYGB, n = 12). Linoleic acid (LA) and sucrose perception thresholds were determined using the three-alternative forced-choice procedure, gut hormones were assayed before and after a test meal and subjective changes in oral food sensations were self-reported using a standardized questionnaire. Despite a global positive effect of both surgeries on the reported gustatory sensations, a change in the taste sensitivity was only found after RYGB for LA. However, the fat and sweet taste perceptions were not homogenous between patients who underwent the same surgery procedure, suggesting the existence of two subgroups: patients with and without taste improvement. These gustatory changes were not correlated to the surgery-mediated modifications of the main gut appetite-regulating hormones. Collectively these data highlight the complexity of relationships between bariatric surgery and taste sensitivity and suggest that VSG and RYGB might impact the fatty taste perception differently.

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