Risk Factors Identified for Early Heavy Drinking

2008 ◽  
Vol 36 (9) ◽  
pp. 27 ◽  
Author(s):  
KERRI WACHTER
Keyword(s):  
2016 ◽  
Vol 62 (7) ◽  
pp. 628-634 ◽  
Author(s):  
Deborath Lucia de Oliveira Diniz ◽  
Pedro Rodrigues Barreto ◽  
Pedro Felipe Carvalhedo de Bruin ◽  
Veralice Meireles Sales de Bruin

Summary Objective: Wake-up stroke (WUS) is defined when the exact time of the beginning of the symptoms cannot be determined, for the deficits are perceived upon awakening. Sleep alterations are important risk factors for stroke and cardiovascular diseases. This study evaluates the characteristics of patients with and without WUS, the presence of daytime sleepiness, and associated risk factors. Method: Patients with ischemic stroke were investigated about the presence of WUS. Clinical and demographic characteristics were evaluated. Stroke severity was studied by the National Institutes of Health Stroke Scale (NIHSS) and the Modified Rankin Scale (MRS), and daytime sleepiness severity was studied by the Epworth Sleepiness Scale (ESS). Results: Seventy patients (57.1% men) aged from 32 to 80 years (58.5±13.3) were studied. WUS was observed in 24.3%. Arterial hypertension (67.1%), type 2 diabetes (27.1%), and hyperlipidemia (22.8%) were frequent. Type 2 diabetes and sedentary lifestyle were more common in patients with WUS (p<0.05). Overall, mild, moderate or very few symptoms of stroke (NIHSS<5) were predominant (62.3%). Among all cases, 20% had excessive daytime sleepiness (ESS>10). No differences were found between patients with and without WUS as regards stroke severity or excessive daytime sleepiness. Patients with excessive daytime sleepiness were younger and had more sedentary lifestyle (p<0.05). Individuals with previous history of heavy drinking had more daytime sleepiness (p=0.03). Conclusion: Wake-up stroke occurs in approximately 25% of stroke cases. In this study, patients with WUS had more diabetes and sedentary lifestyle. Daytime sleepiness is frequent and is associated with sedentary lifestyle and heavy drinking.


2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Hyun Il Seo ◽  
Kyoo-ho Choi ◽  
Koon Hee Han ◽  
Sang Jin Lee ◽  
Jong Kyu Park ◽  
...  

Background and Aims. While several case reports on ischemic colitis (IC) suggest the presence of predisposing causative factors, a few studies have investigated the predisposing factors in IC. This study aimed to identify the characteristics of patients with IC, particularly focusing on the predisposing factors. Methods. We conducted a single-center, retrospective analysis of 159 patients with IC. Clinical characteristics, laboratory data, endoscopic findings, and medical records were reviewed. Data were compared between groups of patients defined according to the predisposing factors. The predisposing factors are defined as temporary states or episodic events occurring within a week before the development of IC such as colonoscopy, enema, use of laxatives, heavy drinking, pancreatitis, shock, and burn. Results. Compared to the group of patients without predisposing factors of IC, the group of patients with predisposing factors was characterized by a relatively higher prevalence of male sex (56.9% versus 33.3%, p=0.005), younger age (60.9 ± 15.4 versus 67.2 ± 13.4 years, p=0.010), lower incidence of hypertension (43.1% versus 60.2%, p=0.044), and fewer risk factors (1.24 ± 1.18 versus 1.82 ± 1.22, p=0.005). Conclusions. Among men with predisposing factors, IC may develop even at a relatively younger age and in the absence of multiple risk factors, suggesting that predisposing factors may be involved in the pathogenesis of IC.


2012 ◽  
Vol 177 (7) ◽  
pp. 789-796 ◽  
Author(s):  
Joah L. Williams ◽  
Meghan E. McDevitt-Murphy ◽  
James G. Murphy ◽  
Ellen M. Crouse

2020 ◽  
Vol 9 (1) ◽  
pp. 41-46
Author(s):  
PM Singh ◽  
S Karmacharya ◽  
S Khadka ◽  
Sc Gautam ◽  
N Joshi

 Introduction: Alcohol is a potent drug that can produce serious psychiatric symptoms including psychosis. It is believed that approximately 3% of alcoholic persons experience auditory hallucinations or paranoid delusions in the context of heavy drinking or withdrawal. Across Nepal, alcohol use varies widely and alcohol dependence is an increasing problem. So this study aims to provide information regarding prevalence and risk factors of Alcohol Induced Psychotic Disorder in context of Nepal. Material And Method: A hosiptal-based cross- sectional study was carried out among 37 patients admitted in psychiatric inpatient ward at Nepal Medical College Teaching Hospital, Kathmandu with the diagnosis of AIPD from the period of Magh 2075 to Poush 2076. Semi-structured proforma developed by department of Psychiatry was used to collect socio- demographic data. The consent was taken from the patients and caregivers and strict inclusion and exclusion criteria were applied. Diagnosis was based on ICD-10 DCR criteria and the collected data was analyzed with SPSS. Results: There were total 37 patients (29 males and 8 females) admitted with the diagnosis of AIPD and the prevalence of AIPD in our study was 6.19%. Among them majority of the patients (35.1%) were of age group (41-50) years and more than half were from rural areas (64.9%). Nearly half of the patients were educated upto primary level (45.9%) and (35.1%) were farmer by occupation. Also Hindus (56.8%) were found to be more associated with AIPD than Buddhist or Christian. Conclusion: The findings of this study concluded that alcohol is a substantial problem in Nepal. The efforts should be used to increase public awareness about the problems associated with alcohol.


2009 ◽  
Vol 31 (2) ◽  
pp. 125-130 ◽  
Author(s):  
Flavio Pechansky ◽  
Raquel De Boni ◽  
Lísia Von Diemen ◽  
Daniela Bumaguin ◽  
Ilana Pinsky ◽  
...  

OBJECTIVE: Brazil lacks information about driving under the influence of alcohol (DUI) originated from representative samples obtained from the general population. METHOD: 333 subjects with a valid driver's license and drinking in the last 12 months were drawn from a multistaged sample of 2,346 adults from the first Brazilian Household Survey of Patterns of Alcohol Use. A multivariate analysis was conducted to understand the associations between risk factors and driving after drinking three or more drinks. RESULTS: the overall DUI prevalence reported in the sample was 34.7% - 42.5% among males and 9.2% among females. Being male (OR = 6.0, 95% CI 2.9-12.6), having a previous DUI accident (OR = 7.9, 95% CI 2.5-24.9), binging in the last year (OR = 2.2, 95% CI 1.03-4.5) and having an unfavorable opinion towards policies (OR = 2.9, 95% CI 1.4-6.2) remained associated with heavy drinking and driving after model adjustments. DISCUSSION: This was the first study evaluating driving under the influence of alcohol in a representative sample of the Brazilian population. The prevalence of DUI found is alarming, and possibly underestimated in the sample. Results demonstrate the need for more studies on this association and show directions towards preventive strategies for the specific high-risk group of male drivers with previous problems with alcohol and unfavorable opinions about prevention policies.


1999 ◽  
Vol 13 (9) ◽  
pp. 753-759 ◽  
Author(s):  
Susan Levenstein

The prevailing concept of peptic ulcer etiology has swung over entirely in just a few years from the psychological to the infectious, yet the rich literature documenting an association between psychosocial factors and ulcer is not invalidated by the discovery ofHelicobacter pylori. Physical and psychological stressors interact to induce ulcers in animal models, concrete life difficulties and subjective distress predict the development of ulcers in prospective cohorts, shared catastrophes such as war and earthquakes lead to surges in hospitalizations for complicated ulcers, and stress or anxiety can worsen ulcer course. Many known ulcer risk factors, including smoking, nonsteroidal anti-inflammatory drug use, heavy drinking, loss of sleep and skipping breakfast, can increase under stress; the association of low socioeconomic status with ulcer is also accounted for in part by psychosocial factors. Among possible physiological mechanisms, stress may induce gastric hypersecretion, reduce acid buffering in the stomach and the duodenum, impair gastroduodenal blood flow, and affect healing or inflammation through psychoneuroimmunological mechanisms. Psychosocial factors seem to be particularly prominent among idiopathic or complicated ulcers, but they are probably operative in run of the millH pyloridisease as well, either through additive effects or by facilitating the spread of the organism across the pylorus, while gastrointestinal damage by nonsteroidal anti-inflammatory drugs can also be potentiated by stress. Although the clinical importance of peptic ulcer is fading along with the millenium, due to secular trends and new therapies, it remains worthy of study as a splendid example of the biopsychosocial model.


1991 ◽  
Vol 10 (6) ◽  
pp. 405-409
Author(s):  
Li Jie ◽  
Quan-Guan Jiang ◽  
Wei-Dong Zhong

On the basis of a general survey conducted in a munitions plant, a case-control study was made on the various risk factors of liver damage induced by trinitrotoluene (TNT) exposure in the plant. One-hundred male cases with occupational TNT liver damage were paired with 100 male controls, one-by-one, for occupation, age and duration (years) of employment. A total of 55 possible risk factors were statistically analysed with a single factor analysis. On the basis of the single analysis, nine factors including drinking, smoking and education were further analysed with a conditional logistic regression model. A calculation was made on the odds ratio (OR) of each factor selected into the model. According to the estimated parameter of the established logistic model, the relative risk of the risk factors could be worked out. Finally, two factors, the amount of ethanol drunk on each occasion and the frequency of drinking every week were selected into the model at the level of a = 0.05. The result showed that these two factors have a dose-response relationship with their OR of occupational TNT liver damage, but there is no connection between smoking and occupational TNT liver damage and no interaction between drinking and smoking. The above results have revealed that people exposed to TNT and with a long history of heavy drinking, have a greater risk of suffering from chronic liver impairment than those that do not drink.


2020 ◽  
Vol 23 (18) ◽  
pp. 3379-3386 ◽  
Author(s):  
Zhi Du ◽  
Liying Xing ◽  
Shuang Liu ◽  
Li Jing ◽  
Yuanmeng Tian ◽  
...  

AbstractObjective:To gain more comprehensive understanding of metabolic syndrome (Mets) among in general Chinese population.Design:Cross-sectional study. Mets was defined by three widely accepted definitions including modified Adults Treatment Panel (ATP) III criteria, International Diabetes Federation (IDF) criteria and harmonized definition. Risk factors were evaluated by using multivariate logistic regression.Setting:Nineteen rural villages in northeast China.Participants:The survey was conducted in September 2017 and May 2018 on 10 926 individuals.Results:According to modified ATP III criteria, IDF criteria and harmonised definition, the overall prevalence of Mets was 41·3 % (95 % CI 40·3, 42·2), 34·2 % (95 % CI 33·2, 35·1) and 44·1 % (95 % CI 43·1, 45·1), respectively. Females had a higher prevalence, and elevated blood pressure was the most frequent. Age, female sex, non-peasant worker, higher BMI and lower-annual income were independent risk factors of Mets in all three definitions (all ps < 0·05). Based on modified ATP III criteria and harmonised definition, heavy drinking was positively correlated with Mets. In contrast, former drinking was inversely associated with Mets.Conclusions:Mets is highly prevalent in rural areas of northeast China. Its independent risk factors include higher age, female sex, non-peasantry worker, higher BMI and lower-annual income. Modified ATP III criteria and harmonised definition may be superior definitions of Mets.


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