Incidence rate and morphyology of cavum septum pellucidum in patients with treatment-resistant schizophrenia, major depression: A structural MRI study

2011 ◽  
Vol 26 (S2) ◽  
pp. 955-955 ◽  
Author(s):  
J. Sun ◽  
J.J. Maller ◽  
L. Guo ◽  
Z.J. Daskalakis ◽  
P.B. Fitzgerald
Keyword(s):  
Structural Mri ◽  
Septum Pellucidum ◽  
Treatment Resistant ◽  
Maximum Width ◽  
Cavum Septum Pellucidum ◽  
Significant Difference ◽  
Length Width ◽  
The Difference ◽  
Developmental Characteristics ◽  
Mri Study

IntroductionSeveral studies have independently suggested that schizophrenia patients are more likely to have an enlarged cavum septum pellucidum (CSP). However, neither finding has been consistently replicated.ObjectivesWe recruited the relatively homogeneity population: treatment resistant schizophrenia (TRS) and treatment resistant depression (TRD).To investigate whether CSP was present more frequently in TRS or TRD patients than controls and the difference of CSP morphological characteristic between groups.Methods1.5-Tesla MRI was used to evaluate the prevalence of CSP and morphology changes in 42 TRS, 45 TRD patients and 30 healthy controls. The CSP length, width and volume were measured using MRIcro and Analyze™ 8.1 software. A CSP equal to or greater than 6 mm in length was defined as big CSP.ResultsTRS Patients had a significantly higher prevalence (6%) of the big CSP than TRD patients (0%) or controls (3.3%) while no significant difference on the prevalence of all CSP (TRS: 64.3%, TRD: 48.9%, controls: 50.0%) or small CSP between groups. Compared with controls or TRD patients, the values of CSP maximum width in patients with TRS were significant lower and CSP length were higher. There was no significant difference in the CSP volume between groups.ConclusionsThe incidence in Big CSP in TRS patients was higher than that of TRS patients or controls. The small CSP may be a kind of normal variant. There were different CSP developmental characteristics between TRS and TRD patients based on the MRI study.

scholarly journals A study on maxillary sinus dimensions by computed tomography in population of Tamil Nadu

2016 ◽  
Vol 05 (02) ◽  
pp. 091-096
Author(s):  
N Muthukumaravel ◽  
K.Y Manjunath
Keyword(s):  
Computed Tomography ◽  
Maxillary Sinus ◽  
Tamil Nadu ◽  
Maximum Width ◽  
Average Width ◽  
Computed Tomographic ◽  
Significant Difference ◽  
The Difference ◽  
The Right ◽  
Maxillary Sinuses

Abstract Background and aims: Maxillary sinuses are the largest of the paranasal sinuses known for variability in their dimensions. The maxillary sinus dimensions can be better ascertained in living by using computed tomography instead of plain radiography. This study was planned for highlighting the variations in the dimensions of the maxillary sinuses of population of Tamil Nadu region. The aims of the present study were to estimate dimensions of the maxillary sinuses on computed tomographic (CT) scan of the head of patients from Tamil Nadu and to compare the data gender wise and sidewise. Material and methods: Maximum width, height and depth of maxillary sinus of both sides were measured in CT - head images of 100 males and 100 females of 20-50 years of age in Tamil Nadu. Comparison of data between genders and sides by applying unpaired student "t" test was done. Results : The mean depth, height and width of both right and left maxillary sinuses were comparatively less in females than the males and the difference was found to be statistically significant ( P <.0001). On comparison between the sides of maxillary sinuses, the depth and the height of maxillary sinus did not show any significant difference in the measurements (p >.05), whereas the width of the left side (23.96 mm) was higher than that of the right side (23.69) and the difference was found to be statistically significant (P<.05). The combined average maxillary sinus dimensions (in mm) for both genders in the study population of Tamil Nadu are as follows: Right side depth: 33.71 ± 1.00; Left side depth : 33.65 ± 1.22; Right side height: 34.66 ± 2.71; Left side height: 34.74± 2.48; Right side width: 23.69 ± 0.78 and Left side width: 23.96 ± 0.86. Conclusion: The dimensions of maxillary sinuses in males were found to be larger than those of females and this difference was statistically significant. The average width of the maxillary sinuses on the left side is significantly more than that of right sided sinuses. Computed tomography measurements of maxillary sinuses may be useful in gender determination.

Cavum septum pellucidum in schizophrenia, affective disorder and healthy controls: a magnetic resonance imaging study

1993 ◽  
Vol 23 (2) ◽  
pp. 319-322 ◽  
Author(s):  
George J. Jurjus ◽  
Henry A. Nasrallah ◽  
Stephen C. Olson ◽  
Steven B. Schwarzkopf
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Imaging Study ◽  
Septum Pellucidum ◽  
Healthy Controls ◽  
Resonance Imaging ◽  
Cavum Septum Pellucidum ◽  
Clinical Difference ◽  
Magnetic Resonance Imaging Mri ◽  
Mri Study

SynopsisMany structural brain abnormalities have been described in schizophrenia, consistent with a neurodevelopmental model for this disease. We report here a study of the cavum septum pellucidum (CSP) in schizophrenia compared to control groups, as well as the clinical correlates of this congenital anomaly in schizophrenia. We conducted a magnetic resonance imaging (MRI) study to compare rates of CSP in schizophrenia (N = 67) v. psychiatric controls (bipolar and schizoaffective, N = 60) and healthy controls (N = 37). Of the controls 18·9 %, and of all psychotic subjects 18·1 % had a CSP of any size and there was no difference in the frequency of large CSP among the groups. Males had higher rates of CSP than females (25% v. 9·7%, P = 0·01) in all groups. Schizophrenics had higher CSP rates than affective patients (25%, v. 10%, P = 0·02). No clinical difference was found between schizophrenics with or without CSP.

scholarly journals The Size and The Shape of Sagittal Otolith of Redtail Scad, Decapterus kurroides Blekeer 1855 from Kema Bay, North Minahasa Regency, North Sulawesi, Indonesia

Omni-Akuatika ◽  
2020 ◽  
Vol 16 (3) ◽  
pp. 99
Author(s):  
Fransine B Manginsela ◽  
Gybert E Mamuaya ◽  
Rizald M Rompas ◽  
Lawrence J L Lumingas
Keyword(s):  
Shape Index ◽  
Growth Patterns ◽  
Width Ratio ◽  
Total Length ◽  
North Sulawesi ◽  
Sagittal Otolith ◽  
Significant Difference ◽  
Length Width ◽  
The Difference ◽  
Otolith Size

This study aimed to examine the difference in the otolith size and otolith shape of redtail scad Decapterus kurrodes between sex in North Sulawesi. The otoliths of D. kurroides were studied for sagitta otolith pair samples of 34 juveniles,   58 females and 75 males from Kema Bay. These pairs sagitta otolith images were interpreted using ImageJ tool to describe the otolith size (length, width, perimeter, and area), then we calculated the shape index (form factor, roundness, circularity, rectangularity, ellipticity and aspect ratio or length-width ratio). No significant difference was found in otolith length between left and right otoliths of juveniles of D. kurroides or called symmetrical but significant differences or asymmetrical were found in all sample, females and males. The regressions of total length against otolith sizes (otolith lengt, otolith width otolith perimeter and otolith area of D. kurroides follow a power function. The growth patterns showed dominant allometric growth in total length–otolith sizes relationships of D. kurroides from Kema Bay, Key Words: size, shape index, otolith, Decapterus kurroides, Kema Bay.

Cavum septum pellucidum (CSP) in treatment resistant schizophrenia

1995 ◽  
Vol 15 (1-2) ◽  
pp. 26
Author(s):  
Robert Conley ◽  
Steven Daviss ◽  
Cathy Gounaris ◽  
Carol Tamminga
Keyword(s):  
Septum Pellucidum ◽  
Treatment Resistant ◽  
Cavum Septum Pellucidum

scholarly journals 368. Incidental Findings on Brain MRI in People Living with HIV

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S193-S193
Author(s):  
Kevin F Hanna ◽  
Harlan R Sayles ◽  
Jennifer O’Neil ◽  
Matthew White ◽  
Tony Wilson ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Incidental Findings ◽  
Brain Mri ◽  
Structural Mri ◽  
Cd4 Count ◽  
People Living With Hiv ◽  
Chi Square ◽  
Significant Difference ◽  
Increased Sensitivity ◽  
Mri Study

Abstract Background HIV infection is associated with an array of neurocognitive changes, collectively referred to as HIV-Associated Neurocognitive Disorder (HAND). These changes have been the subject of a great deal of study, often including structural MRI of the brain. Incidental findings (IF) are a well-known complication of imaging studies done for both diagnostic and research indications, and can pose important ethical and clinical dilemmas. Little is known about the rates and types of IF found on brain MRI in patients with HIV infection. We identified and characterized such findings in participants who participated in a study of neurophysiological markers of HAND. Methods The parent study included 108 HIV-infected adults and 125 demographically matched uninfected controls without cognitive impairment who had undergone T1-weighted structural brain MRI for research purposes. Demographic and diagnostic data were abstracted from the research records. Each MRI study was read by the same neuroradiologist, blind to the participant’s HIV status. IF were classified as vascular, neoplastic, congenital, other neurologic, or non-neurologic. Categorical measures were compared using Pearson chi-square tests while continuous measures were compared using t-tests. Results Among HIV-infected participants, 36/108 (33.3%) had IF compared with 33/125 (26.4%) of controls (P = 0.248). Rates of IF were significantly correlated with increased age in both HIV-infected and control participants. We found no correlation among presence or absence of IF and sex, race/ethnicity, or CD4 count and HAND status for the HIV-infected cohort. The most common categories were neurologic (27), followed by non-neurologic (8), vascular (6), and neoplastic (2) (Table 1). Conclusion If were common in both HIV-infected participants and controls, at higher rates than previously reported, possibly because of increased sensitivity of MRI machines over time. Surprisingly, we found no significant difference between the groups and no correlation with HAND status or CD4 count. Age was the only factor correlated with rates of IF in either HIV-infected participants or controls. To our knowledge, this study is the first of its kind to characterize incidental findings in HIV-infected patients. Disclosures All authors: No reported disclosures.

Longitudinal follow-up of cavum septum pellucidum and adhesio interthalamica alterations in first-episode psychosis: a population-based MRI study

2012 ◽  
Vol 42 (12) ◽  
pp. 2523-2534 ◽  
Author(s):  
C. Trzesniak ◽  
M. S. Schaufelberger ◽  
F. L. S. Duran ◽  
L. C. Santos ◽  
P. G. P. Rosa ◽  
...  
Keyword(s):  
Mood Disorders ◽  
Psychotic Disorders ◽  
Population Based ◽  
First Episode Psychosis ◽  
Septum Pellucidum ◽  
First Episode ◽  
Cavum Septum Pellucidum ◽  
Time Interaction ◽  
Episode Psychosis ◽  
Mri Study

BackgroundNeurodevelopmental alterations have been described inconsistently in psychosis probably because of lack of standardization among studies. The aim of this study was to conduct the first longitudinal and population-based magnetic resonance imaging (MRI) evaluation of the presence and size of the cavum septum pellucidum (CSP) and adhesio interthalamica (AI) in a large sample of patients with first-episode psychosis (FEP).MethodFEP patients (n=122) were subdivided into schizophrenia (n=62), mood disorders (n=46) and other psychosis (n=14) groups and compared to 94 healthy next-door neighbour controls. After 13 months, 80 FEP patients and 52 controls underwent a second MRI examination.ResultsWe found significant reductions in the AI length in schizophrenia FEP in comparison with the mood disorders and control subgroups (longer length) at the baseline assessment, and no differences in any measure of the CSP. By contrast, there was a diagnosis×time interaction for the CSP length, with a more prominent increase for this measure in the psychosis group. There was an involution of the AI length over time for all groups but no diagnosis×time interaction.ConclusionsOur findings suggest that the CSP per se may not be linked to the neurobiology of emerging psychotic disorders, although it might be related to the progression of the disease. However, the fact that the AI length was shown to be shorter at the onset of the disorder supports the neurodevelopmental model of schizophrenia and indicates that an alteration in this grey matter junction may be a risk factor for developing psychosis.

scholarly journals The Anterolateral Ligament: An Anatomic Study on Sex-Based Differences

2017 ◽  
Vol 5 (2) ◽  
pp. 232596711668938 ◽  
Author(s):  
Matt Daggett ◽  
Camilo Helito ◽  
Matthew Cullen ◽  
Andrew Ockuly ◽  
Kyle Busch ◽  
...  
Keyword(s):  
Female Athletes ◽  
Cruciate Ligament ◽  
Lateral Meniscus ◽  
Knee Laxity ◽  
Anterolateral Ligament ◽  
Acl Rupture ◽  
Significant Difference ◽  
Length Width ◽  
The Difference ◽  
Anterior Cruciate

Background: The anterolateral ligament (ALL) has been shown to have an important role in rotatory stability of the knee. While there is abundant research on sex-based differences related to anterior cruciate ligament (ACL) rupture, there is a paucity of literature related to such differences in the ALL. Purpose: To define any sex-based differences in the ALL with regard to length, width, and thickness. Study Design: Descriptive laboratory study. Methods: The ALL was initially evaluated in 165 unpaired knees (92 males and 65 females after exclusion criteria applied). The length, width, and thickness of the ALL were measured using a digital caliper. Width and thickness were measured at the joint line just superior to the lateral meniscus. The Mann-Whitney test and Student t tests were used to compare measurements between males and females. The Pearson product-moment correlation was subsequently used to determine the correlation between height and weight and the statistically different morphometric variables. Results: The mean (±SD) thickness of the ALL in males was 2.09 ± 0.56 mm, almost twice as thick as females (1.05 ± 0.49 mm; P = 8.8 × 10−20). There was also a statistically significant difference in ALL length ( P = 3.8 × 10−7), but no significant difference was found for width. A moderate association was found between donor height and ALL thickness and length. Conclusion: The anatomic measurements of the ALL demonstrate a difference between sexes, and the ALL is significantly thicker in males than females. Clinical Relevance: As the role of the ALL in rotatory stability of the knee becomes better understood, the difference in the thickness of the ALL we have found between the sexes may be another factor why female athletes have an increased incidence of ACL rupture compared with males. This may also help explain why females have issues with knee laxity and rotatory instability.

MRI study of the cavum septum pellucidum in obsessive–compulsive disorder

2009 ◽  
Vol 260 (4) ◽  
pp. 337-343 ◽  
Author(s):  
Myong-Wuk Chon ◽  
Jung-Seok Choi ◽  
Do-Hyung Kang ◽  
Myung Hun Jung ◽  
Jun Soo Kwon
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Septum Pellucidum ◽  
Obsessive Compulsive ◽  
Cavum Septum Pellucidum ◽  
Compulsive Disorder ◽  
Mri Study
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