“Sniffing bladder cancer” – detection of bladder tumours with an electronic nose and ion mobility spectrometry

2018 ◽  
Vol 17 (2) ◽  
pp. e1427
Author(s):  
H. Heers ◽  
J.M. Gut ◽  
A. Hegele ◽  
R. Hofmann ◽  
T. Boeselt ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Detection ◽  
Electronic Nose ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Bladder Tumours

scholarly journals Aroma dynamic characteristics during the drying process of green tea by gas phase electronic nose and gas chromatography-ion mobility spectrometry

LWT ◽  
2021 ◽  
pp. 112691
Author(s):  
Yanqin Yang ◽  
Jiayu Chen ◽  
Yongwen Jiang ◽  
Michael C. Qian ◽  
Yuliang Deng ◽  
...  
Keyword(s):  
Gas Chromatography ◽  
Gas Phase ◽  
Green Tea ◽  
Electronic Nose ◽  
Ion Mobility Spectrometry ◽  
Dynamic Characteristics ◽  
Ion Mobility ◽  
Drying Process

scholarly journals Electronic Nose for Bladder Cancer Detection

2021 ◽  
Vol 5 (1) ◽  
pp. 22
Author(s):  
Heena Tyagi ◽  
Emma Daulton ◽  
Ayman S. Bannaga ◽  
Ramesh P. Arasaradnam ◽  
James A. Covington
Keyword(s):  
Bladder Cancer ◽  
Logistic Regression ◽  
Random Forest ◽  
Sensitivity And Specificity ◽  
Cancer Detection ◽  
Electronic Nose ◽  
Random Forest Classifier ◽  
Urine Samples ◽  
Sparse Logistic Regression ◽  
High Separation

This study outlines the use of an electronic nose as a method for the detection of VOCs as biomarkers of bladder cancer. Here, an AlphaMOS FOX 4000 electronic nose was used for the analysis of urine samples from 15 bladder cancer and 41 non-cancerous patients. The FOX 4000 consists of 18 MOS sensors that were used to differentiate the two groups. The results obtained were analysed using s MultiSens Analyzer and RStudio. The results showed a high separation with sensitivity and specificity of 0.93 and 0.88, respectively, using a Sparse Logistic Regression and 0.93 and 0.76 using a Random Forest classifier. We conclude that the electronic nose shows potential for discriminating bladder cancer from non-cancer subjects using urine samples.

scholarly journals Emerging Endoscopic and Photodynamic Techniques for Bladder Cancer Detection and Surveillance

2011 ◽  
Vol 11 ◽  
pp. 2550-2558 ◽  
Author(s):  
Prashant Patel ◽  
Richard T. Bryan ◽  
D. Michael A. Wallace
Keyword(s):  
Raman Spectroscopy ◽  
Bladder Cancer ◽  
Cancer Detection ◽  
Clinical Evidence ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Photodynamic Diagnosis ◽  
Virtual Cystoscopy ◽  
Spectroscopy Optical ◽  
Bladder Tumours

This review provides an overview of emerging techniques, namely, photodynamic diagnosis (PDD), narrow band imaging (NBI), Raman spectroscopy, optical coherence tomography, virtual cystoscopy, and endoscopic microscopy for its use in the diagnosis and surveillance of bladder cancer. The technology, clinical evidence and future applications of these approaches are discussed with particular emphasis on PDD and NBI. These approaches show promise to optimise cystoscopy and transurethral resection of bladder tumours.

834 Urine based bladder cancer detection by an electronic nose system: First results of a pilot study

2015 ◽  
Vol 14 (2) ◽  
pp. e834 ◽  
Author(s):  
M. Horstmann ◽  
D. Steinbach ◽  
C. Fischer ◽  
A. Enkelmann ◽  
M-O. Grimm ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Pilot Study ◽  
Cancer Detection ◽  
Electronic Nose ◽  
First Results ◽  
Electronic Nose System

scholarly journals Analysis of Volatile Compounds in Sea Bass (Lateolabrax japonicus) Resulting from Different Slaughter Methods Using Electronic-Nose (E-Nose) and Gas Chromatography-Ion Mobility Spectrometry

Molecules ◽  
2021 ◽  
Vol 26 (19) ◽  
pp. 5889
Author(s):  
Yueqi Wang ◽  
Jinxing Li ◽  
Yanyan Wu ◽  
Shengyuan Yang ◽  
Di Wang ◽  
...  
Keyword(s):  
Gas Chromatography ◽  
Volatile Compounds ◽  
Electronic Nose ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Nutritional Value ◽  
Sea Bass ◽  
Lateolabrax Japonicus ◽  
Fishy Odor ◽  
Slaughter Method

Sea bass (Lateolabrax japonicus) is known for its unique flavor and high nutritional value. In this study, the influence of slaughter methods on the volatile compounds (VOCs) in sea bass was investigated using electronic nose (E-nose) technology and gas chromatography-ion mobility spectrometry (GC-IMS). VOCs in raw and cooked sea bass resulting from different slaughter methods were effectively distinguished using both techniques. Aldehydes, ketones, and alcohols were associated with the basic flavor of sea bass, whereas esters, organic acids, and furans enriched the aroma. In raw sea bass, the fishy odor was the strongest in the HSD group (head shot control death), followed by that in the IFD (ice faint to death) and BDS (bloodletting to death) groups. The VOC content increased and stabilized after steaming, enhancing pleasant odors such as fatty and fruity aromas. In cooked sea bass, the content of diacetyl and ethanol was the highest in the EAD group (eugenol anesthesia to death), which may be a residue of eugenol, imparting a distinct irritating chemical odor. Furthermore, abundant (E)-2-octenal, 2-heptanone, benzaldehyde, and esters in the BDS group imparted a strong, pleasant aroma. The findings indicate that heart puncture and bloodletting is the preferred slaughter method to maintain sea bass quality, providing new insights into the volatile changes in sea bass induced by different slaughter methods.

scholarly journals Exhaled Breath Analysis for Lung Cancer Detection Using Ion Mobility Spectrometry

PLoS ONE ◽  
2014 ◽  
Vol 9 (12) ◽  
pp. e114555 ◽  
Author(s):  
Hiroshi Handa ◽  
Ayano Usuba ◽  
Sasidhar Maddula ◽  
Jörg Ingo Baumbach ◽  
Masamichi Mineshita ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Detection ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Breath Analysis ◽  
Exhaled Breath ◽  
Exhaled Breath Analysis ◽  
Lung Cancer Detection
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