scholarly journals A direct fed microbial containing a combination of three-strain Bacillus sp. can be used as an alternative to feed antibiotic growth promoters in broiler production

Author(s):  
Yueming Dersjant-Li ◽  
A. Awati ◽  
C. Kromm ◽  
C. Evans

SummaryThe objective of the study was to test the effect of a direct fed microbial (DFM) on the performance of broilers compared to an antibiotic growth promoter under large scale, commercial production settings. Three dietary treatments were tested in a completely randomized design including: 1) a control (C) diet containing 500 FTU/kg phytase and a mixture of xylanase, amylase, protease ; 2) C+ a specific three-strain combination of Bacillus spp. (DFM) and 3) C+ bacitracin methylene disalicylate (BMD). Six, similar commercial broiler houses (15,300 birds per house) were used to give two replicate houses per treatment. The birds (Hubbard x Cobb500) were fed pelleted and crumbled diets ad libitum throughout the 44 day trial period. Due to the large scale, commercial nature of the trial, no significant differences were observed in production parameters among treatments, except that DFM treatment resulted in significantly lower mortality numbers in the last two days (43 to 44d) compared to the control. However, the DFM treatment group showed numerically higher live bodyweight, lower feed conversion ratio (corrected for body weight and mortality) and lower total mortality weight compared to either the control or BMD groups, resulting in an improved production efficiency factor. When compared to control, using DFM resulted in a gross benefit of US$ 0.06 /bird, while using BMD was not cost effective. In conclusion, DFM containing a three-strain combination of Bacillus spp. may be used as an alternative to antibiotic growth promoters, resulting in economic benefit under commercial production settings in broilers fed commercial diets.

1970 ◽  
Vol 37 (2) ◽  
pp. 99-105 ◽  
Author(s):  
R Chowdhury ◽  
MN Haque ◽  
KMS Islam ◽  
MJ Khan

Potassium diformate (Formi) is odorless, low-corrosive and easy to handle. The European Union (EU) has approved it as non-antibiotic growth promoter, for use in non ruminant feeds. Maximum inclusion level of potassium diformate is 1.8% as registered by the European authorities which can improve weight gain up to 14%. Potassium diformate contains the active ingredients free formic acid as well as formate has the strong anti microbial effect in stomach and also in duodenum. Potassium diformate with its growth promoting and health enhancing effect has proven to be an alternative to antibiotic growth promoters. Its special effect on the micro flora is regarded as the main mode of action. 1.8% potassium diformate in growing pig diets also significantly increase Feed intake and feed conversion ratio was significantly improved where growing pig diets was supplemented with 1.8% potassium diformate. It was also reduced pH in the stomach and duodenum. potassium diformate 0.9% significantly reduced the pH of duodenal digesta. DOI: http://dx.doi.org/10.3329/bjas.v37i2.9887 BJAS 2008; 37(2): 99-105


2010 ◽  
Vol 2010 ◽  
pp. 1-8 ◽  
Author(s):  
Saikat Samanta ◽  
Sudipto Haldar ◽  
Tapan Kumar Ghosh

This study evaluated the efficacy of organic acids as a growth promoter for broiler chickens relative to antibiotic growth promoters (AGPs). Broiler chickens were supplemented with graded doses of an organic acid blend (OAB, 1 g and 2 g/kg diet) and bacitracin methylene disalicylate (BMD, 0.5 g and 1 g/kg diet) for 35 days. Supplementation of OAB improved () feed conversion ratio (FCR) and increased protein accretion (). Dietary acidification caused pH of the gizzard to decline linearly () with the dose of supplemental OAB. In the lower intestine, pH remained unaffected by dietary treatments. Unlike BMD, supplemental OAB selectively promoted growth of lactobacilli in the small intestine. Moreover, compared to BMD, OAB tended to maintain the villi in the small intestine at a greater height. Although benefits of exceeding the dose of supplemental organic acids more than 1 g/kg diet are not always conspicuous, based on the live weight and feed conversion data, supplementation of 2 g organic acid per kg diet may be recommended for total replacement of AGPs in broiler diet.


2017 ◽  
Vol 8 (1) ◽  
pp. 11 ◽  
Author(s):  
Youssef A. Attia ◽  
Mohammed A. Al-Harthi ◽  
Saber S. Hassan

This work aimed at investigating the potential as a growth enhancer of different dietary concentrations of turmeric (Curcuma longa Linn.) as an alternative to oxytetracyline and antibiotics and as comparable to mannan oligosaccharide for broiler chicks. A total of 252 Hubbard broiler chicks at one day of age were distributed randomly in a straight run experimental design among six treatments, each replicated seven times, with six unsexed chicks per replicate. The basal diet was administered without supplements (control group) or supplemented with turmeric at 0.5, 1, and 2 g/kg diet, or with mannan oligosacride (MOS) at 1 g/kg feed or with oxytetracycline (OTC) at 50 mg/kg feed. Growth performance, carcass characteristics, meat quality traits, blood biochemical constituents, antioxidant status and red blood cell (RBCs) were investigated. Turmeric supplementation at 1 g/kg feed significantly improved feed conversion ratio (FCR) and European production index compared to the control group and MOS groups. The results indicated that turmeric can be used at 1 kg/t feed as a phytogenic feed additive as an alternative to OTC or MOS without negative effects on the productive and economic traits of broilers. There were no differences from using OTC and MOS, while there was an increase in the European production efficiency index and the broilers’ health status.


2016 ◽  
Vol 19 (4) ◽  
pp. 917-924 ◽  
Author(s):  
B. Dębski

Abstract Modern commercial pig farming systems inflict increased stress in animals, which often leads to various negative changes in the gastro-intestinal tract, especially in the case of piglets. Ban of antibiotics, used as growth promoters, has caused a need for alternatives to conventional antimicrobials in swine diets. Use of pre-/or probiotics, organic acids and plant extracts is often recommended, but it seems that zinc oxide and cooper salts, which were traditionally included in high doses to piglets diet, possess the highest efficacy. In commercial conditions feeding piglets with high doses of Zn and/or Cu stimulates piglets daily gain and decreases feed conversion factor. However, as heavy metals Zn and Cu tend to accumulate in soil and cause serious environmental pollution of soil and tap-water. Furthermore, high zinc concentrations (2500÷3000 mg/kg feed) in feed may have an impact on development of antimicrobial resistance, and may regulate the expression of genes that modify piglets’ immune response. Therefore, the use of high doses of ZnO and/or Cu salts, as growth promoter, has always been a subject of discussion, and caused different legal status of such treatment in various EU countries. This short review describes current European Food Safety Authority (EFSA) point of view on the use of ZnO in medicated feed. The higher bioavailability of recently introduced new sources or forms of these metals allows for substantial reduction of dietary inclusion rate, which should have a positive outcome for pigs health and the environment.


2019 ◽  
Vol 20 (4) ◽  
Author(s):  
Marinko Vekić ◽  
Živko Klincov ◽  
Stoja Jotanović ◽  
Đorđe Savić

This paper presents the basic production parameters of seven broiler farms with a capacity of 6,000 birds per round in the Banja Luka region, obtained by analysis of production records of 70 rounds, achieved in 2013-2014. Methods of descriptive statistics, one-way analysis of variance and correlation analysis were used. Average values of production parameters were as follows (M±SD): day-old chick weight 43.04±2.63 g; fattening duration 38.91±2.55 days; final chick weight 2.13±0.24 kg; feed conversion ratio 1.80±0.07; total mortality rate 4.07±1.95%, and European production efficiency factor 291.14±22.50. Significant differences were found for average total mortality rate among broiler farms and feed conversion ratio between production years (p0.05). Fattening duration was in positive correlation with feed conversion ratio (0.76, p0.01), final chick weight (0.90, p0.01), but in negative with EPEF (-0.28, p0.05). Comparable production performances could be related to uniform the technology and similar requirements of meat industry, although comprehensive research is suggested for reliable evaluation of broiler farm productivity in the Banja Luka region.


Antibiotics ◽  
2022 ◽  
Vol 11 (1) ◽  
pp. 88
Author(s):  
Charlie Tran ◽  
Ian E. Cock ◽  
Xiaojing Chen ◽  
Yunjiang Feng

The agricultural industry utilizes antibiotic growth promoters to promote livestock growth and health. However, the World Health Organization has raised concerns over the ongoing spread of antibiotic resistance transmission in the populace, leading to its subsequent ban in several countries, especially in the European Union. These restrictions have translated into an increase in pathogenic outbreaks in the agricultural industry, highlighting the need for an economically viable, non-toxic, and renewable alternative to antibiotics in livestock. Probiotics inhibit pathogen growth, promote a beneficial microbiota, regulate the immune response of its host, enhance feed conversion to nutrients, and form biofilms that block further infection. Commonly used lactic acid bacteria probiotics are vulnerable to the harsh conditions of the upper gastrointestinal system, leading to novel research using spore-forming bacteria from the genus Bacillus. However, the exact mechanisms behind Bacillus probiotics remain unexplored. This review tackles this issue, by reporting antimicrobial compounds produced from Bacillus strains, their proposed mechanisms of action, and any gaps in the mechanism studies of these compounds. Lastly, this paper explores omics approaches to clarify the mechanisms behind Bacillus probiotics.


2020 ◽  
Vol 47 (2) ◽  
pp. 161-170
Author(s):  
N. G. Dialoke ◽  
P. A. Onimisi ◽  
M. Afolayan

A feeding trial was conducted to evaluate the performance, serum, lipid, haematology and economic indices of broiler chickens fed diets supplemented with different levels of Chestnut (Castenea sativa) phytobiotic as a replacement for antibiotic growth promoters (AGPs). A total of 300, oneday-old cobb 500 broiler chicks were allotted in a completely randomized design to five dietary treatments each replicated thrice, with 20 chicks per replicate. Chestnutphytobiotics was included at 0, 100, 125 and 150g/100 Kg diet while Oxytetracycline was included at 111g/100kg diet. Data was collected on growth performance, haematology, serum biochemical parameters, lipid profiles and economic indices. All data collected were subjected to analysis of variance and significant differences among treatment means were compared using the Duncan's Multiple Range Test of significance. At the end of the starterphase, result showed that chicks placed on 100g phytobiotics diet had significantly (P<0.05) high final weight and weight gain than other supplemented diets and control. There was significant (P<0.05) differences in the feed conversion ratio. Feed cost per kilogram gain was significantly lower in chicks fed control diet, followed by phytobiotics, however higher feed cost per kilogram gain was recorded for chicks fed diet containing Oxytetracycline. Weight gain was significantly (P < 0.05) higher on oxytetracycline based diet (1783.2g) for finisher phase however, there was an improved values for chicks placed on phytobiotics. Glucose (206.51mg/dL) was significantly higher in treatment diet that contained oxytetracycline. Haematological indices showed that values for white blood cell (91.90x103/μL) and Heterophils (20.63%) were significantly higher in diets containing oxytetracycline than other treatment groups. Values for red blood cell, monocytes, eosinophils and basophils were significantly (P<0.05) higher in broiler chickens fed diets containing 100g phytobiotics . Chestnut phytobiotics reduced the total cholesterol values from 151.13 - 96.55mg/dL when compared to other treatment groups. There were significant(P<0.05) differences in all the villi morphometry parameters measured except for crypt depth. The mean yield cost decreased as the level of phytobiotics increased. In conclusion, supplementation of Chestnut phytobiotics reduced total cholesterol and significantly improved the final weight, weight gain, feed cost per Kg gain and feed conversion ratio for both starter and finisher at 100g/100Kg. Chestnut phytobiotic is therefore a potential replacement for antibiotic growth promoters.


2009 ◽  
Vol 39 (2) ◽  
pp. 522-527 ◽  
Author(s):  
Gerson Neudí Scheuermann ◽  
Anildo Cunha Junior ◽  
Lucas Cypriano ◽  
Alexandre Mossate Gabbi

This study evaluated a phytogenic feed additive for broiler chickens. A total of 1,632 broiler chicks were distributed into four treatments: negative control (without growth promoter); positive control (avilamycine, 10ppm + colistin, 15ppm); and two alternative treatments with 150ppm of phytogenic additive, one with a reduced Ca and P levels diet (PA-R1) and the other with lower energy, and amino acids, besides Ca and P (PA-R2). The trial was conducted with 12 replicates, each consisted of a pen with 34 birds. The alternative diets showed body weight intermediate to the two controls at 42 days, with no significant (P>0.05) treatment effect on feed conversion ratio. No treatment differences (P>0.05) on carcass yield and composition was observed. There was a tendency of abdominal fat lipids saturation, when the phytogenic additive was used, as possible consequence of a decreased level of soybean oil in the diets. A difference (P<0.001) on ingredient consumption profile was observed between the treatments. All together, this study showed a possibility to reduce the cost of total feed used to produce a broilers or a ton of body weight by the utilization of the tested phytogenic additive.


2017 ◽  
Vol 13 (Especial 2) ◽  
pp. 156-163
Author(s):  
Vilson Matias Pinto ◽  
Paulo Ricardo de Sá da Costa Leite ◽  
Mônica Maria de Almeida Brainer ◽  
Brena Cristine Rosário Silva ◽  
Leidyanne Guimarães Silva

The objective of this study was to evaluate the production performance of broilers with the addition of ginger (Zingiber officinale) in broiler diets in starter phases. Were used 630 broiler chicks in a completely randomized design with five treatments and seven repetitions with eighteen birds each. The treatments consist of a reference diet with corn and soybean meal and adding different levels of powdered ginger, five treatments, consisting of positive control, negative control and three levels of ginger (0.50%, 0.75%; 1.0%). Were evaluated at the end of each phase, feed intake, weight gain, feed conversion, body weight, pancreatic weight and length and weight of the intestine. The data will be submitted to analysis of variance and means to regression analysis with 5% significance. No effects of the treatments on the performance variables were observed in the initial stage of creation. With this result, at twenty-one days old, we observed the potential for substitution of growth promoters for powdered ginger. The inclusion of up to 1% of powdered ginger did not affect bird performance providing results similar to positive control treatments with growth promoter.


2008 ◽  
Vol 88 (4) ◽  
pp. 623-629 ◽  
Author(s):  
Pablo Catalá-Gregori ◽  
Serge Mallet ◽  
Angélique Travel ◽  
Juan Orengo ◽  
Michel Lessire

A 36-d trial was conducted to evaluate two potential alternatives to antibiotic growth promoters in broilers. The products tested were a prebiotic (PROFEED®) and a plant extract (XTRACT™). Ross male broiler performance and digestive tract function responses were studied. To evaluate the effect of these potential alternatives alone or in combination, seven diets were tested: positive control avilamycin 10 ppm (PC); negative control antibiotic-free (NC); NC + PROFEED® 600 ppm (P); NC + XTRACT™ 100 ppm (X); NC + PROFEED®/XTRACT™ 600/100 ppm (XPH); NC + PROFEED® /XTRACT™ 450/75 ppm (XPM); NC + PROFEED®/XTRACT™ 300/50 ppm (XPL). From 22 to 36 d of age, body weight gain (BWG) was improved by P, X, and XPM compared with NC (P < 0.05). Throughout the trial, broilers fed PC, P, X and XPL had a better feed conversion ratio (FCR) than those fed NC (P < 0.1). No relevant negative effect was observed for the parameters relative to the digestive tract function: ileal histomorphometry, anaerobic sulphite-reducing bacteria count (ASR), intestinal and caecal pH, caecal volatile fatty acids production (VFA) and litter score (LS). With the higher mixture dose (XPH), no improvement in broiler performance was observed, suggesting no synergistic effect of the two additives. Key words: Broiler, antibiotic growth promoter, plant extract, prebiotic


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