scholarly journals Potassium Diformate : A New Alternative To Antibiotic Growth Promoters

1970 ◽  
Vol 37 (2) ◽  
pp. 99-105 ◽  
Author(s):  
R Chowdhury ◽  
MN Haque ◽  
KMS Islam ◽  
MJ Khan
Keyword(s):  
Growth Promoter ◽  
The European Union ◽  
Feed Conversion ◽  
Growth Promoters ◽  
Main Mode ◽  
Special Effect ◽  
Growing Pig ◽  
Antibiotic Growth Promoters ◽  
Inclusion Level ◽  
Growth Promoting

Potassium diformate (Formi) is odorless, low-corrosive and easy to handle. The European Union (EU) has approved it as non-antibiotic growth promoter, for use in non ruminant feeds. Maximum inclusion level of potassium diformate is 1.8% as registered by the European authorities which can improve weight gain up to 14%. Potassium diformate contains the active ingredients free formic acid as well as formate has the strong anti microbial effect in stomach and also in duodenum. Potassium diformate with its growth promoting and health enhancing effect has proven to be an alternative to antibiotic growth promoters. Its special effect on the micro flora is regarded as the main mode of action. 1.8% potassium diformate in growing pig diets also significantly increase Feed intake and feed conversion ratio was significantly improved where growing pig diets was supplemented with 1.8% potassium diformate. It was also reduced pH in the stomach and duodenum. potassium diformate 0.9% significantly reduced the pH of duodenal digesta. DOI: http://dx.doi.org/10.3329/bjas.v37i2.9887 BJAS 2008; 37(2): 99-105

scholarly journals A direct fed microbial containing a combination of three-strain Bacillus sp. can be used as an alternative to feed antibiotic growth promoters in broiler production

2013 ◽  
Vol 2 ◽  
Author(s):  
Yueming Dersjant-Li ◽  
A. Awati ◽  
C. Kromm ◽  
C. Evans
Keyword(s):  
Large Scale ◽  
Production Efficiency ◽  
Total Mortality ◽  
Commercial Production ◽  
Growth Promoter ◽  
Feed Conversion ◽  
Growth Promoters ◽  
Strain Combination ◽  
Bacillus Spp ◽  
Antibiotic Growth Promoters

SummaryThe objective of the study was to test the effect of a direct fed microbial (DFM) on the performance of broilers compared to an antibiotic growth promoter under large scale, commercial production settings. Three dietary treatments were tested in a completely randomized design including: 1) a control (C) diet containing 500 FTU/kg phytase and a mixture of xylanase, amylase, protease ; 2) C+ a specific three-strain combination of Bacillus spp. (DFM) and 3) C+ bacitracin methylene disalicylate (BMD). Six, similar commercial broiler houses (15,300 birds per house) were used to give two replicate houses per treatment. The birds (Hubbard x Cobb500) were fed pelleted and crumbled diets ad libitum throughout the 44 day trial period. Due to the large scale, commercial nature of the trial, no significant differences were observed in production parameters among treatments, except that DFM treatment resulted in significantly lower mortality numbers in the last two days (43 to 44d) compared to the control. However, the DFM treatment group showed numerically higher live bodyweight, lower feed conversion ratio (corrected for body weight and mortality) and lower total mortality weight compared to either the control or BMD groups, resulting in an improved production efficiency factor. When compared to control, using DFM resulted in a gross benefit of US$ 0.06 /bird, while using BMD was not cost effective. In conclusion, DFM containing a three-strain combination of Bacillus spp. may be used as an alternative to antibiotic growth promoters, resulting in economic benefit under commercial production settings in broilers fed commercial diets.

scholarly journals Antimicrobial Bacillus: Metabolites and Their Mode of Action

Antibiotics ◽  
2022 ◽  
Vol 11 (1) ◽  
pp. 88
Author(s):  
Charlie Tran ◽  
Ian E. Cock ◽  
Xiaojing Chen ◽  
Yunjiang Feng
Keyword(s):  
World Health ◽  
The European Union ◽  
Feed Conversion ◽  
Growth Promoters ◽  
Agricultural Industry ◽  
Antibiotic Growth Promoters ◽  
Health Organization ◽  
Harsh Conditions ◽  
Spore Forming Bacteria ◽  
Upper Gastrointestinal

The agricultural industry utilizes antibiotic growth promoters to promote livestock growth and health. However, the World Health Organization has raised concerns over the ongoing spread of antibiotic resistance transmission in the populace, leading to its subsequent ban in several countries, especially in the European Union. These restrictions have translated into an increase in pathogenic outbreaks in the agricultural industry, highlighting the need for an economically viable, non-toxic, and renewable alternative to antibiotics in livestock. Probiotics inhibit pathogen growth, promote a beneficial microbiota, regulate the immune response of its host, enhance feed conversion to nutrients, and form biofilms that block further infection. Commonly used lactic acid bacteria probiotics are vulnerable to the harsh conditions of the upper gastrointestinal system, leading to novel research using spore-forming bacteria from the genus Bacillus. However, the exact mechanisms behind Bacillus probiotics remain unexplored. This review tackles this issue, by reporting antimicrobial compounds produced from Bacillus strains, their proposed mechanisms of action, and any gaps in the mechanism studies of these compounds. Lastly, this paper explores omics approaches to clarify the mechanisms behind Bacillus probiotics.

scholarly journals Propionic Acid Is An Alternative To Antibiotics In Poultry Diet

1970 ◽  
Vol 38 (1-2) ◽  
pp. 115-122 ◽  
Author(s):  
MN Haque ◽  
R Chowdhury ◽  
KMS Islam ◽  
MA Akbar
Keyword(s):  
Propionic Acid ◽  
Antimicrobial Effect ◽  
Inhibitory Effect ◽  
Feed Additive ◽  
Growth Promoters ◽  
Reduction Activity ◽  
Antibiotic Growth Promoters ◽  
Inclusion Level ◽  
Growth Promoting ◽  
Bacteriostatic Property

Propionic acid (PA) is a fungicide and bactericide, registered to control fungi and bacteria in stored grains, hay, grain storage areas, poultry litter, and drinking water for livestock and poultry. European Union (EU) certifies PA as the great of grain preserver and most efficient in controlling Salmonella and other pathogens. Recently it is used as feed additive in poultry and non-ruminant production. Suitable inclusion level of PA is 0.2 to 0.4% which can improve the overall performances of poultry. The preservative effect of PA is due to its antibacterial and mould inhibitory effect. High bacteriostatic property of PA is due to its pH reduction activity both in feed and gastrointestinal tract through pharmacogenic action on microflora. Propionic acidA with its growth promoting, health enhancing and antimicrobial effect has proven to be an effective alternative to antibiotic growth promoters in food animal production. DOI: http://dx.doi.org/10.3329/bjas.v38i1-2.9920 BJAS 2009; 38(1-2): 115-122

scholarly journals Comparative Efficacy of an Organic Acid Blend and Bacitracin Methylene Disalicylate as Growth Promoters in Broiler Chickens: Effects on Performance, Gut Histology, and Small Intestinal Milieu

2010 ◽  
Vol 2010 ◽  
pp. 1-8 ◽  
Author(s):  
Saikat Samanta ◽  
Sudipto Haldar ◽  
Tapan Kumar Ghosh
Keyword(s):  
Small Intestine ◽  
Organic Acids ◽  
Organic Acid ◽  
Broiler Chickens ◽  
Live Weight ◽  
Growth Promoter ◽  
Feed Conversion ◽  
Growth Promoters ◽  
Antibiotic Growth Promoters ◽  
Dietary Treatments

This study evaluated the efficacy of organic acids as a growth promoter for broiler chickens relative to antibiotic growth promoters (AGPs). Broiler chickens were supplemented with graded doses of an organic acid blend (OAB, 1 g and 2 g/kg diet) and bacitracin methylene disalicylate (BMD, 0.5 g and 1 g/kg diet) for 35 days. Supplementation of OAB improved () feed conversion ratio (FCR) and increased protein accretion (). Dietary acidification caused pH of the gizzard to decline linearly () with the dose of supplemental OAB. In the lower intestine, pH remained unaffected by dietary treatments. Unlike BMD, supplemental OAB selectively promoted growth of lactobacilli in the small intestine. Moreover, compared to BMD, OAB tended to maintain the villi in the small intestine at a greater height. Although benefits of exceeding the dose of supplemental organic acids more than 1 g/kg diet are not always conspicuous, based on the live weight and feed conversion data, supplementation of 2 g organic acid per kg diet may be recommended for total replacement of AGPs in broiler diet.

scholarly journals Supplementation of pigs diet with zinc and copper as alternative to conventional antimicrobials

2016 ◽  
Vol 19 (4) ◽  
pp. 917-924 ◽  
Author(s):  
B. Dębski
Keyword(s):  
Legal Status ◽  
Tap Water ◽  
Substantial Reduction ◽  
Farming Systems ◽  
Short Review ◽  
Growth Promoter ◽  
Feed Conversion ◽  
Growth Promoters ◽  
High Zinc ◽  
High Doses

Abstract Modern commercial pig farming systems inflict increased stress in animals, which often leads to various negative changes in the gastro-intestinal tract, especially in the case of piglets. Ban of antibiotics, used as growth promoters, has caused a need for alternatives to conventional antimicrobials in swine diets. Use of pre-/or probiotics, organic acids and plant extracts is often recommended, but it seems that zinc oxide and cooper salts, which were traditionally included in high doses to piglets diet, possess the highest efficacy. In commercial conditions feeding piglets with high doses of Zn and/or Cu stimulates piglets daily gain and decreases feed conversion factor. However, as heavy metals Zn and Cu tend to accumulate in soil and cause serious environmental pollution of soil and tap-water. Furthermore, high zinc concentrations (2500÷3000 mg/kg feed) in feed may have an impact on development of antimicrobial resistance, and may regulate the expression of genes that modify piglets’ immune response. Therefore, the use of high doses of ZnO and/or Cu salts, as growth promoter, has always been a subject of discussion, and caused different legal status of such treatment in various EU countries. This short review describes current European Food Safety Authority (EFSA) point of view on the use of ZnO in medicated feed. The higher bioavailability of recently introduced new sources or forms of these metals allows for substantial reduction of dietary inclusion rate, which should have a positive outcome for pigs health and the environment.

scholarly journals Combination on endophytic fungal as the Plant Growth-Promoting Fungi (PGPF) on cucumber (Cucumis sativus)

2021 ◽  
Vol 22 (3) ◽  
Author(s):  
Syamsia Syamsia ◽  
ABUBAKAR IDHAN ◽  
AMANDA PATAPPARI FIRMANSYAH ◽  
NOERFITRYANI NOERFITRYANI ◽  
IRADHATULLAH RAHIM ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Plant Growth ◽  
Cucumis Sativus ◽  
Endophytic Fungi ◽  
Growth Promoter ◽  
Growth Promoters ◽  
Cucumis Sativus L ◽  
Plant Growth Promoting ◽  
Growth Promoting ◽  
Phosphate Solubilizing

Abstract. Syamsia S, Idhan A, Firmansyah AP, Noerfitryani N, Rahim I, Kesaulya H, Armus R. 2021. Combination on endophytic fungal as the Plant Growth-Promoting Fungi (PGPF) on Cucumber (Cucumis sativus). Biodiversitas 22: 1194-1202. Endophytic fungi are known to stimulate plant growth by producing secondary metabolites, including phytohormones (IAA and Gibberellins), siderophore, phosphate-solubilizing metabolites. In this study, a total of six endophytic fungi were successfully isolated from local rice plants and showed different abilities in producing secondary metabolites, during single isolates testing. These six isolates were then combined to obtain 15 combinations for analysis, to determine the best combination for application as a plant growth promoter. Subsequently, each combination was tested for phytohormones (IAA, gibberellins) and siderophore (quantitatively)-producing activity, phosphate-solubilizing ability, and the effect on cucumber (Cucumis sativus L) plant growth. F13 showed activity in producing IAA and produced the highest gibberellin levels, while F1 exhibited the highest phosphate-solubilizing activity. In addition, F11 (Na-salicylate) and F1 (catechol) showed the highest siderophore activity, while a combination of F6, F8, F9, and F12 successfully increased plant height growth. Also, F4 increased the root growth, while the fresh weight of cucumber was increased by F8 treatment, under controlled conditions. Molecular analysis showed the tested isolates have close similarity to Daldinia eschscholtzii, Sarocladium oryzae, Rhizoctonia oryzae, Penicillium allahabadense, and Aspergillus foetidus. The combination of endophyte fungal isolates showed potential as plant growth promoters, however, further testing on several plant types is required before the combination is to be widely applied.

scholarly journals Dietary non-pharmacological alternatives to the use of antibiotics as growth promoters in swine

2007 ◽  
Vol 23 (5-6-1) ◽  
pp. 77-85
Author(s):  
G. Biagi
Keyword(s):  
Dietary Supplements ◽  
The European Union ◽  
Human Pathogens ◽  
Growth Promoters ◽  
Antibiotic Resistant ◽  
Immune Development ◽  
Low Weight ◽  
Growth Performances ◽  
Decision Alternative ◽  
Antibiotic Growth Promoters

The first weeks after weaning are a critical stage for piglets characterized by high incidence of diarrhoea and low weight gain. These problems were counteracted with the use of antibiotic growth promoters that may as a side-effect induce the selection of antibiotic-resistant genes in animal and human pathogens. For this reason, the European Union decided to completely ban the antibiotics used as growth promoters as of January 2006. As a consequence of this decision, alternative strategies to modulate the piglet gastrointestinal environment have been the object of many studies. The use of non-pharmaceutical dietary supplements, such as organic acids, prebiotics, probiotics, and essential oils has been shown to improve piglet post-weaning health and growth performances but results are sometimes controversial. Moreover, the role of molecules that can influence gastrointestinal and immune development in the newly weaned piglet has been investigated. The proper choice and use of a non-pharmacological dietary supplement might improve piglet productivity but it has to be considered that dietary supplements usually increase the feed price, which means that the gains in productivity should exceed the increased costs.

scholarly journals Effect of a bovine colostrum supplementation in piglet diet at weaning on growth performances, food ingestion and faecal E. coli concentrations

2005 ◽  
Vol 2005 ◽  
pp. 85-85
Author(s):  
C. Boudry ◽  
I. Didderen ◽  
J. Wavreille ◽  
D. Portetelle ◽  
J-P Dehoux ◽  
...  
Keyword(s):  
High Availability ◽  
Bovine Colostrum ◽  
Food Ingestion ◽  
Weaned Piglets ◽  
Growth Promoters ◽  
High Concentration ◽  
E Coli ◽  
Growth Performances ◽  
Antibiotic Growth Promoters ◽  
Growth Promoting

In the perspective of the complete ban of antibiotic growth promoters use in animal food by 2006, many alternatives have been studied. However, most of them are not yet technically and/or economically competitive with antibiotics. In this way, the incorporation of bovine colostrum in piglet diets has been studied. Bovine colostrum was chosen for its high concentration in growth promoting and anti-microbial peptides (Playford et al., 2000) and for its high availability. The aims of this study were to measure the efficiency of a bovine colostrum supplementation on growth performances of newly weaned piglets and to evaluate its effects on the digestive and immunological troubles involved by weaning (Pluske et al., 1997 and Vega-Lopez et al., 1995).

Performance, blood parameters and economic indices of broiler chickens fed graded levels of chestnut (Castenea sativa) phytobiotics as replacement for antibiotics growth promoters

2020 ◽  
Vol 47 (2) ◽  
pp. 161-170
Author(s):  
N. G. Dialoke ◽  
P. A. Onimisi ◽  
M. Afolayan
Keyword(s):  
Weight Gain ◽  
Broiler Chickens ◽  
Conversion Ratio ◽  
Feed Conversion ◽  
Growth Promoters ◽  
Treatment Groups ◽  
Feed Cost ◽  
Final Weight ◽  
Antibiotic Growth Promoters ◽  
Economic Indices

A feeding trial was conducted to evaluate the performance, serum, lipid, haematology and economic indices of broiler chickens fed diets supplemented with different levels of Chestnut (Castenea sativa) phytobiotic as a replacement for antibiotic growth promoters (AGPs). A total of 300, oneday-old cobb 500 broiler chicks were allotted in a completely randomized design to five dietary treatments each replicated thrice, with 20 chicks per replicate. Chestnutphytobiotics was included at 0, 100, 125 and 150g/100 Kg diet while Oxytetracycline was included at 111g/100kg diet. Data was collected on growth performance, haematology, serum biochemical parameters, lipid profiles and economic indices. All data collected were subjected to analysis of variance and significant differences among treatment means were compared using the Duncan's Multiple Range Test of significance. At the end of the starterphase, result showed that chicks placed on 100g phytobiotics diet had significantly (P<0.05) high final weight and weight gain than other supplemented diets and control. There was significant (P<0.05) differences in the feed conversion ratio. Feed cost per kilogram gain was significantly lower in chicks fed control diet, followed by phytobiotics, however higher feed cost per kilogram gain was recorded for chicks fed diet containing Oxytetracycline. Weight gain was significantly (P < 0.05) higher on oxytetracycline based diet (1783.2g) for finisher phase however, there was an improved values for chicks placed on phytobiotics. Glucose (206.51mg/dL) was significantly higher in treatment diet that contained oxytetracycline. Haematological indices showed that values for white blood cell (91.90x103/μL) and Heterophils (20.63%) were significantly higher in diets containing oxytetracycline than other treatment groups. Values for red blood cell, monocytes, eosinophils and basophils were significantly (P<0.05) higher in broiler chickens fed diets containing 100g phytobiotics . Chestnut phytobiotics reduced the total cholesterol values from 151.13 - 96.55mg/dL when compared to other treatment groups. There were significant(P<0.05) differences in all the villi morphometry parameters measured except for crypt depth. The mean yield cost decreased as the level of phytobiotics increased. In conclusion, supplementation of Chestnut phytobiotics reduced total cholesterol and significantly improved the final weight, weight gain, feed cost per Kg gain and feed conversion ratio for both starter and finisher at 100g/100Kg. Chestnut phytobiotic is therefore a potential replacement for antibiotic growth promoters.

scholarly journals Phytogenic additive as an alternative to growth promoters in broiler chickens

2009 ◽  
Vol 39 (2) ◽  
pp. 522-527 ◽  
Author(s):  
Gerson Neudí Scheuermann ◽  
Anildo Cunha Junior ◽  
Lucas Cypriano ◽  
Alexandre Mossate Gabbi
Keyword(s):  
Body Weight ◽  
Broiler Chickens ◽  
Positive Control ◽  
Negative Control ◽  
Feed Additive ◽  
Broiler Chicks ◽  
Growth Promoter ◽  
Feed Conversion ◽  
Growth Promoters ◽  
The Cost

This study evaluated a phytogenic feed additive for broiler chickens. A total of 1,632 broiler chicks were distributed into four treatments: negative control (without growth promoter); positive control (avilamycine, 10ppm + colistin, 15ppm); and two alternative treatments with 150ppm of phytogenic additive, one with a reduced Ca and P levels diet (PA-R1) and the other with lower energy, and amino acids, besides Ca and P (PA-R2). The trial was conducted with 12 replicates, each consisted of a pen with 34 birds. The alternative diets showed body weight intermediate to the two controls at 42 days, with no significant (P>0.05) treatment effect on feed conversion ratio. No treatment differences (P>0.05) on carcass yield and composition was observed. There was a tendency of abdominal fat lipids saturation, when the phytogenic additive was used, as possible consequence of a decreased level of soybean oil in the diets. A difference (P<0.001) on ingredient consumption profile was observed between the treatments. All together, this study showed a possibility to reduce the cost of total feed used to produce a broilers or a ton of body weight by the utilization of the tested phytogenic additive.

Sign in / Sign up

Export Citation Format

Share Document