scholarly journals Brain executive laterality and hemisity

2020 ◽  
Vol 3 ◽  
Author(s):  
Bruce Eldine Morton

Abstract Brain laterality refers to the asymmetric location of functional elements within the bilateral brain of animals and humans. Thus far, five lateralized functions have been recognized in humans: handedness, language ability, spatial skills, facial recognition, and emotion recognition. Recently, a sixth asymmetric functional element bearing on personality has been discovered. It is the larger side of the split bilateral anterior cingulate cortex (ACC). This appears to be the final output element of the executive system of which, by logic, there can be only one. Which side is somewhat larger varies among the general population in a seemingly idiosyncratic manner, yet with a genetic basis because true-breeding lineages exist. Here, hemisity is binary measure where a person is inherently born either right brain or left brain oriented. This is determined by nine statistically robust sets of four biophysical tests, none of which depend upon personality, and five behavioral questionnaires. Crucially these hemisity methods have been validated by the Magnetic Resonance Imaging (MRI)-based discovery that the larger side of the ACC is on the same side as one’s hemisity, making MRI the primary standard for hemisity determination (r = 0.96). There are at least 30 measurable differences in individual characteristics and behaviors between those persons whose hemsity is on the right compared to those with it on the left. The hemisity of 2929 individuals was determined by these methods. Large groups included 1428 junior and senior high schools students both in Hawaii and Utah. There were somewhat comparable numbers present for both types of hemisity. Hemisity of individuals was found stable from infancy to old age. There was no relation between hemisity and handedness. Larger corpus callosum (CC) size of male or female subjects was larger in right brainer that in left brainers. Twin studies demonstrate that CC size is inherited. Thirty-eight percent of individuals of both sexes were right brain oriented, while 62% of individuals of both sexes were left brain oriented. In pairings, there were more than twice as many couples with opposite hemisity. Of these couples, the right brain male and females were dominant. Reproductive outcomes of these were “Like father like son, Like mother like daughter.”

2002 ◽  
Vol 205 (12) ◽  
pp. 1795-1805 ◽  
Author(s):  
Helmut Prior ◽  
Frank Lingenauber ◽  
Jörg Nitschke ◽  
Onur Güntürkün

SUMMARY The pigeon's use of different visuo-spatial cues was studied under controlled laboratory conditions that simulated analogous aspects of a homing situation. The birds first learned the route to a goal that was not visible from the starting location, but became visible as it was approached. Birds could orientate within a mainly geometric global reference frame, using prominent landmarks within their range, or by `piloting' along local cues. After learning the route, the birds were tested from familiar and unfamiliar release points, and several aspects of the available cues were varied systematically. The study explored the contribution of the left and right brain hemispheres by performing tests with the right or left eye occluded. The results show that pigeons can establish accurate bearings towards a non-visible goal by using a global reference frame only. Furthermore, there was a peak of searching activity at the location predicted by the global reference frame. Search at this location and directedness of the bearings were equally high with both right and left eye, suggesting that both brain hemispheres have the same competence level for these components of the task. A lateralization effect occurred when prominent landmarks were removed or translated. While the right brain hemisphere completely ignored such changes,the left brain hemisphere was distracted by removal of landmarks. After translation of landmarks, the left but not the right brain hemisphere allocated part of the searching activity to the site predicted by the new landmark position. The results show that a mainly geometric global visual reference frame is sufficient to determine exact bearings from familiar and unfamiliar release points. Overall, the results suggest a model of brain lateralization with a well-developed global spatial reference system in either hemisphere and an extra capacity for the processing of object features in the left brain.


Leonardo ◽  
2011 ◽  
Vol 44 (5) ◽  
pp. 405-410 ◽  
Author(s):  
Anjan Chatterjee ◽  
Bianca Bromberger ◽  
William B. Smith ◽  
Rebecca Sternschein ◽  
Page Widick

We know little about the neurologic bases of art production. The idea that the right brain hemisphere is the “artistic brain” is widely held, despite the lack of evidence for this claim. Artists with brain damage can offer insight into these laterality questions. The authors used an instrument called the Assessment of Art Attributes to examine the work of two individuals with left-brain damage and one with right-hemisphere damage. In each case, their art became more abstract and distorted and less realistic. They also painted with looser strokes, less depth and more vibrant colors. No unique pattern was observed following right-brain damage. However, art produced after left-brain damage also became more symbolic. These results show that the neural basis of art production is distributed across both hemispheres in the human brain.


2021 ◽  
Vol 4 (2) ◽  
pp. 1-19
Author(s):  
Connie Laurina

God created humans as the most special creation compared to His other creations. Human intelligence is caused by one organ which, although small in size, has a very vital role, namely the brain. Advances in knowledge and technology have encouraged scientists to try solving the mysteries of the brain. Many studies have focused on the right brain and left brain, or to balance the right brain and left brain. But in recent years, there has been a training/self-development institute who stated that they had found a way to balance the right and left brain, namely by activating the midbrain. This midbrain activation method is aimed at children aged 5-15 years because it is considered that children at this age are more easily activated in a very short time through a computer.The method used in writing this work is a Literature Study that contains various information on matters related to the topic of discussion. In addition to using literature, writing will be complemented by field research, using a Check List to interview respondents. The research approach used are qualitative and quantitative approach. A The qualitative approach obtains data regarding respondent's experiences. This writing has the aim of finding ( knowing ) whether the Midbrain Activation system is in accordance with God's Word or against God's Word; to open the horizons of parents, congregations and even readers of this paper, especially those with children, so that they can be more careful in choosing training for their children.


2019 ◽  
Vol 21 (Supplement_6) ◽  
pp. vi256-vi256
Author(s):  
Shubhanchi Nigam ◽  
Lauren McCarl ◽  
Rajeev Kumar ◽  
Carolyn Anderson ◽  
Barry Edwards ◽  
...  

Abstract Glioblastoma is a lethal brain tumor, heavily infiltrated by tumor-associated myeloid cells (TAMCs). As up to 30% of a glioma cellular mass may be attributed to immunosuppressive myeloid cells, including myeloid-derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs). TAMCs impede natural and immunotherapy-driven anti-tumor responses, they are a high-priority and promising therapeutic target currently being evaluated in clinical trials. Multiple preclinical and clinical trials have attempted to target these cells, however monitoring of biologic responses to therapy remains a challenge. Quantifying real time status of MDSCs and TAMs at the tumor site using non-invasive immunoPET could improve therapeutic response and allow for better patient stratification and monitoring of targeted treatment responses. TAMCs highly expressed the cell surface marker, integrin CD11b (Mac-1, αMβ2) and may be a highly effective imaging target for immunoPET strategies. The human/mouse cross-reactive anti-CD11b antibody (clone M1/70) was radiolabeled with 89Zr for PET imaging. PET/CT imaging, with or without a blocking dose of anti-CD11b Ab, was performed in mice bearing established orthotopic syngeneic GL261 gliomas. Flow cytometry and histology in tissues collected from post-imaging biodistribution validated targeting of CD11b+ MDSCs and TAMs. There was significant Zr-89-anti-CD11b Ab uptake in the tumor ipsilateral right brain (SUVmean = 2.6 ± 0.24) compared to contralateral left brain (SUVmean = 0.6 ± 0.11). Blocking with 10-fold lower specific activity 89Zr-anti-CD11b Ab reduced the SUV in right brain with (SUVmean = 0.11 ± 0.06). Immune rich organs spleen and lymph nodes showed high uptake. These results correlated with biodistribution analysis. CD11b expression in the right and left brain were validated using flow cytometry, H&E and IHC, showing high CD11b expression in the right brain. Imaging TAMs and MDSCs with 89Zr-labeled anti-CD11b Ab targeting was validated in a mouse model of malignant gliomas, demonstrating the feasibility of monitoring immune response during immunotherapy.


1986 ◽  
Vol 58 (3) ◽  
pp. 823-830 ◽  
Author(s):  
Alice Kienholz ◽  
John Hritzuk

59 students in architecture and 50 medical students were compared using two questionnaire-defined measures of cognitive style. The Inquiry Mode Questionnaire (InQ) measured cognitive style according to five major dimensions: synthesist, idealist, analyst, realist and pragmatist. Your Style of Learning and Thinking (SOLAT)—Form C, now published as the Human Information Processing Survey (HIP Survey), measured preference for one of three main styles: a visuospatial, nonlinear, holistic, right-brain style; a verbal, analytic, sequential, left-brain style; and an integrated style involving an integration of the right and left styles. Significant differences were found for the two groups on the two questionnaires. Students in architecture favored the idealist style on the InQ and right-brain style on the SOLAT. Medical students favored the realist style on the InQ and the left-brain style on the SOLAT. Association between the InQ synthesist-idealist combined scores and the SOLAT inferred right-brain style and between the InQ analyst-realist style and the SOLAT left-brain style were observed.


1988 ◽  
Vol 16 (4) ◽  
pp. 343-348
Author(s):  
Harold J. MCWhinnie

This article presents a more theoretical discussion of the use of the microcomputer, selective computer graphics programs, as basic experiences which relate as much to right as to the left side of the brain. It reviews some selected research literature in art education which shows the importance of the right brain in various areas of creative behavior and drawing skills, and argues that while the computer has been shown as the sine qua non of left brain activity, conceptual and analytical thought processes, one can also approach it from a right brain perspective. This article details a personal experience of the use of computer with the right brain approach in computer graphics and computer assisted design.


2019 ◽  
pp. 108705471985568
Author(s):  
Margarete Klein ◽  
Fábio Luis Souza-Duran ◽  
Anny Karinna Pires Mendes Menezes ◽  
Tania Maria Alves ◽  
Geraldo Busatto ◽  
...  

Objective: To investigate total and selected region-of-interest-based gray matter volume (GMV) in older adults with ADHD. Method: Twenty-five elderly (≥65 years old) patients with ADHD and 34 healthy controls underwent 1.5-T magnetic resonance imaging (MRI). We used voxel-based morphometry to compare GMV between groups and performed a correlation analysis with ADHD symptoms and comorbidities. Results: Findings revealed a smaller total GMV in males with ADHD and a smaller GMV in the right medial frontal orbital area extending toward the medial frontal superior, the frontal superior, and the subgenual anterior cingulate cortex (ACC) besides correlations between inattentiveness and ACC (bilaterally) and left cerebellum, hyperactivity/impulsivity and the left frontal inferior orbital, depression and caudate (bilaterally), and the right inferior parietal lobule. Conclusion: Neural correlates in regions related to attention, executive control, and affective processing suggest that impairments in frontostriatal and frontoparietal-cerebellar areas observed in adults with ADHD persist into old age.


PALAPA ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 351-368
Author(s):  
Baiq Yuni Wahyuningsih ◽  
M. Abdurrahman Sunni

This study aims to see an overview of the use of the right and left brain of STMIK Mataram students and how much it affects the achievement of their learning outcomes. This type of research is a descriptive study with a quantitative approach. Data collection was carried out through questionnaires and test questions. The data analysis technique was carried out by using descriptive statistics and simple regression analysis to determine the closeness of the correlation coefficient between the independent variable (X), namely the level of use of the right brain and left brain and the dependent variable (Y), namely student learning outcomes. The results showed that in general, the level of use of the students' right brain was moderate with a percentage of 34.375%. The number of students who think using the right brain in the very high category is 6.25%, the high category is 31.25%, the low and very low category is 25% and 3.125%. The level of use of the students' left brain is classified as moderate with a percentage of 56.25%. Students who think using the left brain are in the very high category of 9.375%, the high category is 15.625%, the low and very low category is 12.5% ​​and 6.25%. Meanwhile, for the achievement of learning outcomes in general, the learning outcomes score was classified into the low category with a value range of 53 - 65 as many as 12 people (37.5%), 8 people (25%) and very high respectively. 4 people (12.5%). While the determinant coefficient obtained was 31.7%. In other words, that the use of the right brain and left brain has an effect of 31.7% on the calculus learning outcomes achieved by students.


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