Endogenous pulsing and stimulated release of growth hormone in dairy calves of high and low genetic merit

1993 ◽  
Vol 56 (1) ◽  
pp. 1-8 ◽  
Author(s):  
J. A. Woolliams ◽  
K. D. Angus ◽  
S. B. Wilson

AbstractFifty-five calves aged 105 days of age, of both sexes, belonging to two genetic groups (H, high or L, low) differing in their predicted breeding value (PBV) by 78 kg for fat plus protein yield, were individually penned for 3 weeks with the final 2 weeks on a diet designed to provide energy close to their maintenance requirements. The calves were then cannulated in the jugular vein and blood was sampled every 15 min for 25 h. Following this a growth hormone releasing factor (GRF) preparation was administered on up to four occasions, being one of (per kg live weight) either 0·2 or 0·4 μg GRF (treatments SGRF or DGRF respectively) or 0·2 μg thyrotropin releasing hormone (TRH). On each occasion blood samples were taken at −15, 4, 8,12,16, 20 and 45 min relative to the time of administration and up to four further occasions, one prior to and three within 32 min of administration. Samples were assayed for growth hormone (GH).GH concentration of troughs prior to an episode of GH release was 1·19-fold greater in H compared with L calves with concentrations decreasing to 0·9 of their previous values each h. Trough and peak concentrations had repeatabilities of 0·21 and 0·26 respectively (both P < 0·05). There was no association between PBV and either peak concentrations, number of pulses (4·84 per 25 h) or mean GH concentration (13·3 μg/l).GH released was only 1·11-fold greater after DGRF than SGRF. The difference in the regression coefficients for PBV between SGRF and DGRF was small, as it was for the difference between coefficients for the two sexes. The pooled coefficient was 0·00342 loge units per kg (s.e. 0·00157; P< 0·05) indicating a 1·31-fold greater response in H than in L calves. The correlation between responses to SGRF and DGRF was 0·482 and the repeatability of SGRF was 0·338; a pooled repeatability was estimated as 0·362(P < 0·01). The regression of GH release on PBV for TRH was 0·00345 (s.e. 0·00330). For all secretagogues, response depended on prior concentrations.It was concluded that GH release following GRF administration was positively related to PBV in dairy calves and response was moderately repeatable; furthermore, although aspects of endogenous secretion may be related to PBV they suffer from measurement difficulties.

2019 ◽  
Vol 57 ◽  
pp. 60-67
Author(s):  
G. D. Іlyashenko

Dairy cattle breeding is one of the leading livestock sectors whose purpose is to ensure the production of high quality dairy raw materials in volumes meeting the scientifically grounded standards of state food security and expanding the export potential of the agrarian sector. The purpose of our research was to study the status and prospects of dairy cattle breeding in the Kirovograd region. Material and methods of research. The research was carried out on the basis of the electronic database of breeding goals (including 2312 cows), official statistics and estimates of cattle of various breeds that are involved in the production of dairy direction in the breeding farms of the Kirovograd region. The analysis used zootechnical and statistical methods. The calculations were carried out using the software package "STATISTICA-6,1" Results. According to the research (2001–2018), the cattle population in the Kirovograd oblast decreased by a factor of 2.6. Thus, as of January 1, 2018, its number constituted 96.3 thousand heads in all categories of farms, 53.1 thousand of them were cows, the number of which also decreased by 2.4 times. Specific gravity of cattle population of farms remains significant and makes up 72.7%, and 80.6% in the livestock of cows. The largest number of cows of agricultural enterprises declined significantly. Thus, as of January 1, 2018, their number was 10.3 thousand goals, which is 4.7 times less than in the same period of 2001. In the households there is also a tendency for a permanent reduction of cows, the difference is, respectively, 37.0 thousand heads or 46.4% The development of dairy cattle breeding is characterized by two opposite tendencies: reduction of livestock of cows and increase of their productivity. Thus, in agricultural enterprises in 2010, compared to 2000, hopes per cow increased by 2.5 times, in all categories of farms by 1.8 times. In 2017, the increase in dairy costs in agricultural enterprises compared to 2010 amounted to 60.0% in farms of all categories 12.2%. The researches found that in the agricultural enterprises of the oblast as of January 1, 2018 there are 26256 head of cattle, including 10281 cows. The breeding part of the existing cows is 3.013 heads, 29.3% of the total number located in 10 breeding farms. The analysis of the genealogy structure showed that the experimental population of cows belongs to 18 lines and related groups of which the most numerous Chifa 1427381 – 20.4%, Starbuck 352790 – 20.1%, Henev 1629391 – 18.6% , Eleusis 1491007 – 11.2%, Family 267150 – 10.8%. Among the indicated lines, the lowest level of milk productivity was first-born cows. The 1491007, the milk of milk for 305 days of lactation was 4466 ± 99.8 kg, and the milk fat was 168.2 ± 6.5 kg. Analogues l Starbak 352779 was characterized by the highest milk productivity, its level was 5696 + 98.8 kg and 224.9 ± 9.7 kg, respectively. The difference in stomach was 1230 ± 140.4 kg (td = 10.2) and at the release of milk fat 56.7 ± 5.28 kg (td = 10.2) at P < 0.001. However, the latter were markedly less service life (125 against 168 days) and logically higher reproduction rate compared to other lines. An analysis of the intensity of the formation of live weight of young animals has been established for its highest growth in heifers of controlled herds in the period from 9 to 12 months. Thus, in animals of Ukrainian red breed, the growth rate of live weight during this period was 75 kg, Ukrainian red-shrimp 61 kg, Ukrainian black-and-white 73 kg, Holstein 76 kg. Accordingly, during this period, the average daily gain of live weight of young breeds of these breeds was 833 g; 678 g; 811 g, 835 g. The sharp fluctuations of average daily increments during growing periods, first of all, testify to the unequal conditions of growing and feeding young animals than the breed differences. In general, as a result of the analysis of the formation of live weight of heifers, a significant level of phenotypic variability was observed, which confirms sufficient genetic resources and preconditions for selection on the given sign. Therefore, proceeding from the above, in the long run, selection work for breeding improvement of cattle breeding farms of the Kirovograd region should be conducted in accordance with certain promising directions according to groups of breeds. Conclusions. A very important factor in the growth of milk production in the Kirovograd region is high-yield pedigree cattle. The main task on the way of bringing breeding cases in dairy farming to the modern level is the introduction of computer breeding records in breeding farms. This will allow to estimate in the near future bulls-pedigrees, which were used in the past in these farms, to allocate among them complex improvers for precisely the specific conditions and maximally attract them for reproduction. On the other hand, a reliable clogging of poor quality in the genetic sense of sperm production, which leads to negative consequences, will be posed. When establishing the assessment of the breeding value of bulls and developing a single plan of breeding and breeding work in the region, one can proceed to the next step of improving breeding and breeding business, introducing a progressive method of raising the breeding value of animals of large-scale breeding. As a result, the profit from the breeding of highly productive animals, well adapted to specific conditions, will significantly exceed the costs. At the same time, the proposed measures will allow the breeding business to be brought up to the modern world level and stimulate highly productive cattle breeding.


2017 ◽  
Vol 19 (74) ◽  
pp. 48-51
Author(s):  
L. V. Ferenz

The influence of bullock`s different breeding value for reproductive ability and milk production of their  daughters were investigated. Established that the age of first productive insemination of heifers Ukrainian black spotted milk breed, was 17.5–18.6 months and age of first calving – 26.6–27.8 months. Heifers` live weight at the first insemination was 361.4–407.1 kg. During first lactation the highest productivity had daughters from parents with breeding value by milk yield more than 801 kg. In the first lactation wasn’t found significant difference in duration service-period and interparturition-period for cows derived from progenitors with different breeding value. In the second lactation best indexes in duration service-period and interparturition-period for cows derived from progenitors with breeding value by milk yield 601–800 kg and more than 801 kg. In the third, the highest lactation, these indexes were best for cows derived from progenitors with breeding value by milk yield 601–800 kg. The difference in milk yield during first lactation between heifers received from progenitors with breeding value by milk yield less than 200 kg and heifers from bullock`s  with breeding value 401–600 kg was 292 kg. The difference in milk yield between heifers received from progenitors with breeding value by milk yield less than 200 kg and heifers from bullock`s  with breeding value  with breeding value 601–800 kg  was 660.3 kg. The difference in milk yield between heifers received from progenitors with breeding value by milk yield less than 200 kg and heifers from bullock`s  with breeding value more than 801 kg was  920.8 kg In the second lactation this difference was 589.8 (Р < 0.001), 841.5 (Р < 0.001) і 894.4 (Р < 0.001) kg of milk, in the third, the highest lactation – 754.5 (Р < 0.001), 951.8 (Р < 0.001) і 1335.7 кг (Р < 0.001).


Author(s):  
Х.А. АМЕРХАНОВ ◽  
Ф.Г. КАЮМОВ ◽  
Р.Ф. ТРЕТЬЯКОВА

Изучено влияние однонуклеотидного полиморфизма в гене гормона роста на изменчивость весового роста помесных телок 2-го поколения абердин-ангусской × калмыцкой породы. От рождения до отъема молодняка различия по величине живой массы между носителями разных вариантов генотипа по гену гормона роста были незначительными. В возрасте 1 года превосходство телок с гетерозиготным генотипом достигло 20,8 кг (Р<0,05). На заключительном этапе выращивания (18 мес) преимущество по величине живой массы между подопытными животными увеличилось до максимального значения — 23,9 кг (Р<0,05). За период от 8 до 18 мес разница по среднесуточному приросту составляла 71,4 кг. В целом за период проведения опыта зафиксировано достоверное превосходство носителей желательного аллеля (L) по скорости весового роста на 41,6 кг. Максимальный эффект фактора наследственности на изменчивость живой массы был выявлен в возрасте 12 мес — 28,27% (Р<0,05). В более поздние периоды выращивания влияние генотипа на весовой рост телок несколько ослабло, но по-прежнему достоверно определяло вариабельность весового роста молодняка. The influence of single-nucleotide polymorphism in the growth hormone gene on the variability of weight growth of mixed heifers of the 2nd generation of the Aberdeen-Angus × Kalmyk breed was studied. From birth to weaning of young animals, the differences in live weight between carriers of different genotype variants for the growth hormone gene were insignificant. At the age of 1 year, the predominance of heifers with a heterozygous genotype reached 20.8 kg (P<0.05). At the final stage of rearing (18 months), the advantage in terms of live weight between the experimental animals increased to a maximum value of 23.9 kg (P<0.05). For the period from 8 to 18 months the difference in average daily gain was 71.4 kg. In general, during the period of the experiment, a significant superiority of carriers of the desired allele (L) in terms of weight growth rate by 41.6 kg was recorded. The maximum effect of the heredity factor on the variability of body weight was revealed at the age of 12 months. — 28.27% (P<0.05). In the later periods of rearing, the influence of the genotype on the weight growth of heifers somewhat weakened, but it still reliably determined the variability in the weight growth of the young.


2019 ◽  
Vol 14 (3) ◽  
pp. 101-110
Author(s):  
K. A. Katkov ◽  
L. N. Skorykh ◽  
V. S. Pashtetsky ◽  
P. S. Ostapchuk ◽  
T. A. Kuevda

Aim. Traditionally, prediction of breeding values of male small horned ruminants   (rams) by referring to levels of economically useful traits of their progeny is carried  out by methods of statistical analysis. However, at the same time, there is a forecasting method based on the use of a mixed biometric model. The solution of the system  of equations constituting a mixed biometric model is associated with certain difficulties caused by the peculiarity of the system matrix. It is proposed to use integrated  mathematical packages in the forecast, by which the system of equations can be  solved in several ways, followed by analysis of the results. The prediction of progeny  values is carried out by statistical methods using three statistical tests, as well as with  the use of a mixed biometric model. It is of interest to compare estimates obtained  by using statistical methods with estimates using a mixed biometric model. Material and Methods. The initial data set was the live weight of Qigai rams, the  progeny of a group of sixteen rams belonging to eight genetic groups.   Results. It was found that the forecast of breeding values of each animal using a  mixed biometric model substantially clarifies the rank of each animal in the group  being evaluated.   Conclusion. The refinement of the estimation of breeding value is related to the  effects of the genetic groups to which the animals belong in the mixed model, as well  as the degree of relationship between them. Also the mixed model also allows one to  isolate environmental effects from the overall assessment. Solving the system of  equations in several ways will improve the reliability of the forecast.


1993 ◽  
Vol 56 (3) ◽  
pp. 285-291 ◽  
Author(s):  
P. Løvendahl ◽  
K. Sejrsen

AbstractIn two experiments Red Danish dairy calves of both sexes, and of two lines selected for high (H) and low (L) milk fat production (proportional difference 0·22), were tested at 4 months and again at 10 months of age for their growth hormone (GH) release following intravenous administration of either thyrotropin releasing hormone (TRH, experiment 1: 0·15 μig/kg live weight, no. = 16 H + 10 L) or arginine hydrochloride (ARG, experiment 2: 0·10 g/kg live weight, no. = 19 H + 10 L). The GH response was measured in serial blood samples for 0·5 h prior to and for 2 h following intravenous injections. The response peak, measured as the geometric mean of the 5-, 10- and 15-min samples following TRH was greater in the line selected for high yield, at 10 months (H, 42·4 μg/l; L, 20·6 μig/l; P < 0.01) but not at 4 months of age (H, 25·4 μg/l; L, 18·6 μg/l; P > 0·05). The response peak following arginine measured in the 20-, 30- and 45-min samples was smaller than the peak following TRH and did not differ between selection lines, although there was a tendency for H calves to have a larger release at 10 months of age. After puberty (10 months) male calves responded more to both secretagogues than females, while there was no difference before puberty (4 months). These results suggest that GH release may be useful as a juvenile predictor of dairy merit, but results need to be confirmed in further and larger studies.


1990 ◽  
Vol 70 (1) ◽  
pp. 309-312 ◽  
Author(s):  
R. N. KIRKWOOD ◽  
P. A. THACKER ◽  
R. S. KORCHINSKI ◽  
B. LAARVELD

Twenty-three prepubertal Yorkshire × Landrace gilts were allocated to receive daily injections of either porcine growth hormone (pGH) or vehicle for 6 consecutive days. At the time of first pGH or buffer injection, all gilts received an injection of 500 IU PMSG. Blood samples were taken by jugular vein puncture at 0, 24 and 48 h then every 12 h until 96 h then every 8 h until 144 h. Samples were assayed for triiodothyronine (T3), insulin, glucose and LH. Treatment with pGH elevated (P < 0.01) serum concentrations of T3, insulin and glucose, and was associated with a reduced (P < 0.05) LH surge height. Fewer pGH-treated than vehicle-treated gilts ovulated (4/12 vs. 7/11), but the difference was not significant. Key words: Gilts, growth hormone, gonadotrophins, ovulation


2020 ◽  
Vol 15 (4) ◽  
pp. 586-593
Author(s):  
C.M. Sat ◽  
◽  
E.S. Oorzhak ◽  
C.K. Oorzhak ◽  
G.L. Oyun ◽  
...  

Numerous studies have shown that animals with the same genetic potential can differ in productiveness. In this regard, specialists in this industry, when predicting the milk productivity of adult animals in the process of raising young cattle, divide rearing into separate periods. In order to study the conditions for growing dairy calves, a comparative analysis of the conditions for keeping and feeding calves in two farms of the Republic of Tyva was carried out. The conditions of growing calves in the dairy period in the conditions of different farms with the same breed composition of cattle were studied. A comparative analysis of the influence of the composition and level of the diet on the growth of young animals is given. Calves of both groups by birth weight at birth did not have significant differences: they were 0.05-0.07 kg. In dairy farms MUP “KaaKhemsky” and “OOO Turanskoye” young cattle from birth to 6 months are kept in separate rooms. There are no significant differences in the calf feeding schedule. In the Municipal Unitary Enterprise “Kaa-Khemsky” feeding with haylage of young animals is introduced from two months of age; at the farm of “OOO Turanskoye” silage has been given to calves from 4 months. However, from 4 months to six months of age, they showed a significant difference in the increase in live weight. At 4 months, the difference averaged 4.27 kg, at 5 and 6 months – 6.39 and 8.59 kg, respectively. As a result of the studies, it was concluded that a decrease in the drinking of whole milk and the introduction of a substitute at its early, three-month-old age, which are compensated by a large intake of hay, feed and silage, do not provide a high average daily gain in live weight of the growing organism of young cattle.


2017 ◽  
Vol 53 ◽  
pp. 124-130 ◽  
Author(s):  
T. P. Koval

Among the most important parts of improving breeding Ukrainian Red Dairy breed is not the most important place belongs to the intensive use of bull-sires with high breeding value, which is determined by the capacity daughters. Materials and methods of research. Studies conducted on materials zotehnichnoho primary accounting and breeding breeding farm "Zarya" Kherson region for the period 2010-2012. The object of the research was the daughter of the Ukrainian Red dairy bulls, Holstein (red and white suit), Angler and Red Steppe breeds. Studied cows milk production estimated by yields for the full complete (minimum of 240 days) lactation, content and output of milk fat and protein for 305 days and at higher daily milk yield. Results. The study revealed a significant level of intergroup differentiation and specificity for milk production, reproductive ability, soundings and indices of body structure cows daughters of different bulls. Specifically found that the highest milk yield inherent daughters bull V.Din Et Reda 5661918, which is almost twice prevailed worst analogues daughters Radar 4439 respectively 2484 kg of milk, 93.0 kg of milk fat and milk protein 66.9 kg. The highest daily yield characteristic daughters H.Ch.Herri 5839897, and the lowest - for daughters Radar 4439. The difference in this case was 9.4 kg of milk. Inter-group differentiation on fat and protein in milk is low and under 0.12 and 0.22% by live weight - 14 kg. The difference between  the grounds daughters play different bulls more clearly expressed and 232 days is the age of first calving for the daughters Zenit 1113 and at a rate of 0.201 reproductive capacity for daughters H.Ch.Herri 5839897. It should be noted that although the daughters Zenit 1113 and were the youngest among firstborn both had the lowest rate of reproductive capacity after the first calving. Research has found that the highest measurements of height at withers and depth of chest inherent daughters bull Sharpe 9713, prevailing daughters Zenit 1113 respectively by 5.8 and 2.9 cm. For indirect soundings chest width body length and chest girth advantage daughter had Grybka 696, and the largest width in maklakah typical for daughters of Napoleon 1647. Inter-differentiation daughters by different bulls metacarpus circumference small and is just 0.4 cm, due what difference the index kostystosti as insignificant and is only 1%. Conclusions. Found significant levels of intergroup differentiation and specificity studied groups of cows his father napivsester the main qualitative and quantitative characteristics of milk productivity, exterior, reproductive capacity and live weight.


2016 ◽  
Vol 52 ◽  
pp. 82-94 ◽  
Author(s):  
A. Ye. Pochukalin

One of the ways of increasing level of animal economically useful traits is selection work with farm families. In pedigree cattle breeding of Ukraine families are a statistical component of breed genealogy. Among the main scientific works on working with families, it should be noted minimum number of female ancestors, proposed by D. T. Vinnichuk, to determine the breeding value, different categories, classification and techniques for evaluating related groups of females. The aim of our research was to analyse importance of farm families for genealogical structure of the breed. The research was on basis of data of primary breeding records at the herd of Volyn Beef cattle of “Zorya” breeding farm, Kovel district, Volyn region. Akula 102, Galka 37 and Galka 1537 families belonging to Krasavchyk 3004 bloodline, Smorodyna 613, Korona 2382 and Visla 1016 families – Tsebryk 3888 bloodline, Kalyna 212, Verba 1536 and Garna 536 families – Yamb 3066 bloodlines, Kazka 433, Galka 421 and Bystra 1124 families – Buinyi 3042 bloodline, Rozetka 1313, Arfa 599 and Bulana 943 families – Sonnyi-Kaktus 3307-9828 bloodline, and Palma 275, Desna 870 and Veselka 444 families – Mudryi 9100 bloodline were characterized. Belonging to a bloodline was determined by the father's side of female ancestors. Structural units of families: branches, branching with identifying the best individuals on breeding traits were submitted to identify the best combinations and successful use of closely related breeding. Comparing assessment of related groups of females on the main breeding traits belonging to Krasavchyk 3004 bloodline, it was noted that the cows of Akula 102 family predominated in live weight at 5 years’ age, milk ability and economic use duration, whereas the cows of Galka 1537 family – on traits of reproductive ability. Smorodyna 613 family of Tsebryk 3888 bloodline had high duration of economic use and cows’ live weight at 5 years’ age compared with Korana 2382 and Visla 1016 families with equal values of the exterior traits (height measures) and coefficient of reproductive ability. The families of Mudryi 9100 bloodline in terms of reproduction (calving interval, coefficient of reproductive ability) had the highest figures of cows’ milk ability and live weight. The cows of Bulana 943 family had a considerable predominance over representatives of Rozetka 1313 and Arfa 599 families of Sonnyi-Kaktus 3307-9828 bloodline by main economically useful traits. High indices of reproductive ability were noted in these families. Heifers of the families of Buinyi 3042 bloodline had high live weight at 18 months’ age at average values of milk ability and cows’ live weight at 5 years’ age. More equal figures of growth rate, exterior and economic use duration were observed in the cows of Kalyna 212, Verba 1536 and Garna 536 families of Yamb 3066 bloodline. Breeding by families in beef cattle breeding is an important element of selection, because it allows to evaluate not only related group of female ancestor, but also to analyse a successful combination with lines and purposeful use of closely related breeding by the best representatives of a breed.


Author(s):  
N.V. SIVKIN ◽  
N.V. STREKOZOV ◽  
V.I. CHINAROV

В симментальской породе предусматривается разведение скота, сбалансировано сочетающего молочную и мясную продуктивность. Однако в практике совершенствования племенных стад в подборах быков доминируют улучшатели удоя, что во многом предопределяет результаты селекции и продуктивный тип животных. Объектом нашего исследования стало стадо чистопородного симментальского скота в условиях стойловой системы беспривязного и привязного содержания коров. Для изучения эффективности использования быков-производителей разного племенного достоинства сформировали 2 опытные группы: I состояла из бычков, полученных от отцов с племенной ценностью (ПЦ) по удою 100 кг и более, а во II с ПЦ от 0 до 100 кг молока. Симментальские бычки, отобранные для контрольного убоя, достигали весовых кондиций 500 кг и более в 17,5 мес при среднесуточном приросте 911 г. При использовании на маточном поголовье быков-производителей с улучшающим эффектом по удою 100 кг и более, их сыновья (I группа), на фоне более высоких суточных приростов (на 30 г) и раннем возрасте достижения живой массы 500 кг (на 18 дней) имели массу и выход туши на 21,4 кг и 2,7 ниже, чем у бычков II группы. При формировании молочно-мясного типа быки-производители с умеренной племенной ценностью по удою обеспечивали получение потомства, сочетающего молочную и мясную продуктивность в экономически значимых пропорциях.The Simmental breed provides for the breeding of cattle that combines milk and meat productivity in a balanced proportion. However, in the practice of improving breeding herds, the selection of bulls is dominated by milk yield improvers, which largely determines the results of selection and the productive type of animals. The object of our research was a breeding herd of purebred Simmental cattle in variety feeding and housing practices. To study the effectiveness of using bulls-producers of different breeding values, 2 experimental groups were formed: I consisted of bulls received from fathers with a breeding value (BV) of milk yield 100 kg or more, and II with a BV from 0 to 100 kg of milk. Simmental bulls selected for control slaughter reached weight standards of 500 kg or more in 17.5 months with an average daily increase of 911 g. When used on breeding of bulls with an improving effect on the yield of 100 kg or more, their sons (group I), against the background of higher daily gains (30 g) and an early age of reaching a live weight of 500 kg (18 days), had a mass and carcass yield of 21.4 kg and 2.7 lower than that of group II bulls. When forming a dairy-meat type, producing bulls with a moderate breeding value for milk yield provided for the production of offspring that combined dairy and meat productivity in economically significant proportions.


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