The effect of age on tooth loss and the performance of Masham ewes

1984 ◽  
Vol 39 (3) ◽  
pp. 421-425 ◽  
Author(s):  
J. E. Newton ◽  
Caroline Jackson
Keyword(s):  
Tooth Loss ◽  
Live Weight ◽  
The Other ◽  
Lower Jaw ◽  
Upper Jaw ◽  
Group 2 ◽  
Lamb Growth ◽  
Effect Of Age ◽  
Marked Drop ◽  
Group 1

ABSTRACTThe rate of incisor, pre-molar and molar tooth loss was studied in two groups of Masham ewes, one from 8·75 to 12·25 years of age, and the other from 7·25 to 9·25 years of age. Incisors were lost at the rate of 0·93 per year in group 1 and pre-molars from the lower jaw at the rate of 1·04 per year. The rate of loss of molars from the lower jaw and pre-molars from the upper jaw was much slower, whilst there was virtually no loss of molars from the upper jaw.Mean litter size declined gradually from age 7 in group 1, but there was no decline up to age 9 years in group 2. Lambing percentage declined gradually from age 6 years, with a marked drop after age 10 years caused by an increase in barrenness and lamb mortality. Selling percentage also began to decline from age 6 years but dropped sharply after age 9 years following an increase in the number of lambs having to be reared by hand. Ewe live weight, lamb birth weight and lamb growth to 4 weeks of age showed no decline up to 12 years of age.

Reducing Gingivitis Remotely using the iGAM mHealth app (part 2): Prospective Observational Study (Preprint)

2020 ◽  
Author(s):  
Guy Tobias ◽  
Assaf B Spanier
Keyword(s):  
Oral Health ◽  
Tooth Loss ◽  
Prospective Observational Study ◽  
Dental Clinics ◽  
Significant Difference ◽  
Observational Cohort ◽  
Group 2 ◽  
And Behavior ◽  
Oral Hygiene Habits ◽  
Group 1

BACKGROUND Gingivitis is a non-painful, inflammatory condition that can be treated with home remedies. Left untreated gingivitis can lead to tooth loss. Periodic dental examinations are important for early diagnosis and treatment of gum diseases. In order to contain the spread of the corona virus, governments, including in Israel, have restricted movements of their citizens which has caused routine dental checkups to be postponed. OBJECTIVE This study aimed to examine the ability of an mHealth app- iGAM to reduce gingivitis. METHODS A prospective observational cohort study was performed, 160 unpaid participants were divided into 2 equal groups and downloaded the iGAM app. Group 1 photographed their gums weekly for eight weeks. Group 2 photographed their gums at the time of recruitment and 8 weeks later. After photo submission, the participants received the message "It is recommended to read the information contained within the app regarding maintaining oral hygiene habits". A single blinded researcher examined the images and scored them according to the Modified Gingival Index (MGI). RESULTS The average age of group 1 was 26.77 (S.D. ± 7.43), and 28.53 (S.D. ± 10.44) for group 2. The majority were male (74.7% in group 1 vs. 66.7% in group 2), most participants described themselves as "secular", most were "single", non-smokers (74.7% vs. 78.4%) and did not take medications (85.3% vs. 78.4%). 126 subjects completed the study. A statistically significant difference (P <.001) was found in the dependent variable (MGI) in a linearly negative manner. As time passed, the gum condition improved, there were significantly lower gingivitis scores in group 1 (M = 1.16, S.D. ± 1.18) compared to group 2 (M = 2.16, S.D. ± 1.49), after eight weeks. Those with more recent dental visits had a lower MGI (p = .037). No association was found between knowledge and behavior, most participants were familiar with the recommendations for maintaining oral health, yet they only performed some. CONCLUSIONS A dental selfie taken once a week using an mHealth app (iGAM) reduced the signs of gingivitis and promoted oral health. During the current pandemic where social distancing recommendations may be causing people to avoid dental clinics, this app can remotely promote gum health. CLINICALTRIAL The protocol was approved by Hadassah research ethics committee (IRB, 0212-18-HMO)

Myeloid neoplasms in the setting of chronic lymphocytic leukaemia/chronic lymphocytic leukaemia-like disease: a clinicopathological study of 66 cases comparing cases with prior history of treatment to those without

2021 ◽  
pp. jclinpath-2020-207334
Author(s):  
Catherine Luedke ◽  
Yue Zhao ◽  
Jenna McCracken ◽  
Jake Maule ◽  
Lian-He Yang ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
Lymphocytic Leukaemia ◽  
The Other ◽  
Prior History ◽  
Myeloid Neoplasm ◽  
Myeloid Neoplasms ◽  
History Of ◽  
Cytogenetic Profile ◽  
Group 2 ◽  
Group 1

AimsMyeloid neoplasms occur in the setting of chronic lymphocytic leukaemia (CLL)/CLL-like disease. The underlying pathogenesis has not been elucidated.MethodsRetrospectively analysed 66 cases of myeloid neoplasms in patients with CLL/CLL-like disease.ResultsOf these, 33 patients (group 1) had received treatment for CLL/CLL-like disease, while the other 33 patients (group 2) had either concurrent diagnoses or untreated CLL/CLL-like disease before identifying myeloid neoplasms. The two categories had distinct features in clinical presentation, spectrum of myeloid neoplasm, morphology, cytogenetic profile and clinical outcome. Compared with group 2, group 1 demonstrated a younger age at the diagnosis of myeloid neoplasm (median, 65 vs 71 years), a higher fraction of myelodysplastic syndrome (64% vs 36%; OR: 3.1; p<0.05), a higher rate of adverse unbalanced cytogenetic abnormalities, including complex changes, −5/5q- and/or −7/7q- (83% vs 28%; OR: 13.1; p<0.001) and a shorter overall survival (median, 12 vs 44 months; p<0.05).ConclusionsMyeloid neoplasm in the setting of CLL/CLL-like disease can be divided into two categories, one with prior treatment for CLL/CLL-like disease and the other without. CLL-type treatment may accelerate myeloid leukaemogenesis. The risk is estimated to be 13-fold higher in patients with treatment than those without. The causative agent could be attributed to fludarabine in combination with alkylators, based on the latency of myeloid leukaemogenesis and the cytogenetic profile.

Comparison of the productivity of Texel and Rouge de l’Ouest ewes and their crosses

2002 ◽  
Vol 75 (3) ◽  
pp. 459-468 ◽  
Author(s):  
L. E. R. Dawson ◽  
A. F. Carson ◽  
L. O. W. McClinton
Keyword(s):  
Growth Rate ◽  
Weight Gain ◽  
Live Weight ◽  
The Other ◽  
Superior Performance ◽  
Live Weight Gain ◽  
Low Levels ◽  
Lamb Growth ◽  
Average Figure

AbstractAn experiment was undertaken to compare the productivity of crossbred ewes, produced by crossing Texel sires with Rouge de l’Ouest (Rouge) dams and Rouge sires with Texel dams, relative to purebred Texel and Rouge ewes. The purebred and crossbred ewes were crossed with Rouge and Texel sires. The proportion of productive ewes was similar in the purebred and crossbred ewes with an average figure of 0·92. Irrespective of crossing sire, Rouge ewes produced 0·48 more lambs per ewe lambed than Texel ewes (P < 0·001). The two crossbred ewe types (Texel ✕ Rouge and Rouge ✕ Texel) each produced similar numbers of lambs (on average 1·92 lambs per ewe lambed). Individual heterosis values for ewe fertility and prolificacy were small and not significant (–1·67 for the proportion of productive ewes and –3·14 for the number of lambs born per ewe lambed). Maternal heterosis values were also not significant but were of larger magnitude (6·26 for ewe fertility and 3·12 for prolificacy). Lamb mortality (number of lambs born dead per ewe lambed) at birth was similar for purebred Rouge (0·44) and Texel (0·30) ewes and was significantly reduced by crossbred matings and mating the crossbred ewes (individual heterosis –30·68, P < 0·10; maternal heterosis –80·23, P < 0·001). Individual and maternal heterosis values for lamb growth rate from birth to six weeks were 8 (P < 0·05) and 4 (P > 0·05) respectively. Lamb growth rate from birth to weaning was significantly lower in lambs from Texel ewes compared with those from the other genotypes (P < 0·05). Individual and maternal heterosis values for live-weight gain from birth to weaning were 5 (P < 0·10) and 5 (P < 0·01). The results of the current study demonstrate the superior performance of purebred Rouge ewes compared with purebred Texel ewes in terms of prolificacy and lamb growth rate from birth to weaning. However, both breeds had high lamb mortality at birth. Crossbreeding led to the production of hybrid ewes which had relatively high prolificacy with low levels of dystocia and lamb mortality.

scholarly journals Comparison of peribulbar anesthesia and topical anesthesia on outcome of phacoemulsification

2017 ◽  
Vol 5 (6) ◽  
pp. 2608 ◽  
Author(s):  
Rishi Mehta ◽  
Sharda Punjabi ◽  
Nutan Bedi ◽  
Chandra Kant Nagar
Keyword(s):  
Intraoperative Complications ◽  
Visual Outcome ◽  
Topical Anesthesia ◽  
Satisfaction Score ◽  
The Other ◽  
Patients Satisfaction ◽  
Peribulbar Anesthesia ◽  
Group 2 ◽  
A Prospective Study ◽  
Group 1

Background: Due to advancement in phacoemulsification techniques, there has been growing shift from peribulbar anesthesia (PA) to topical anesthesia (TA). But dilemma exists regarding the supremacy of one over the other as both types have certain advantages and disadvantages.Methods: A prospective study was conducted. Patients were divided into two groups. Group-1 underwent PA while group-2 underwent TA. Satisfaction score of patients and surgeons and incidence of complications were noted. The data was analyzed.Results: Lowest patients’ satisfaction score among group-1 vs. group-2 was 160 (87.9%) vs.82 (45.81%). Highest surgeons satisfaction score among group-1 and group-2 was 74(40.65%) vs. 2(1.1%). Intraoperative complications among the group-1 and group-2 were 35 (19.2%) vs. 86(48.0%).Conclusions: While TA provides initial painless phase of surgical procedure, PA results in lesser intraoperative complications resulting in better visual outcome.

Detection Of Potentially Embolic Intracardiac Thrombus In Patients With Cerebral Ischaemia

1981 ◽  
Author(s):  
R M Donaldson ◽  
C Humphrey ◽  
R W Emanuel ◽  
C Earl
Keyword(s):  
Cerebral Ischaemia ◽  
Clinical Evidence ◽  
The Other ◽  
Intracardiac Thrombus ◽  
Cardiac Assessment ◽  
Patients At Risk ◽  
Group 2 ◽  
Histological Confirmation ◽  
A Prospective Study ◽  
Group 1

In a prospective study, 5 8 consecutive patients presenting clinically with transient or permanent focal cerebral ischaemia underwent cardiac assessment which included twodimensional echocardiography (2DE). All had been referred after neurological investigations failed to establish the underlying cause of the neurological event. 5 0 of these patients had no evidence of heart disease (Group 1); the other 28 patients had clinical evidence of an underlying cardiac abnormality or arrhythmia (Group 2). One of the patients in Group 1 had echocardiographic evidence of mitral valve prolapse; no cardiac pathology was visualised in the other 29 patients in this group. In 5 of the 28 patients from Group 2, intracardiac thrombus presumed responsible for the neurological manifestations was demonstrated by 2DE and histological confirmation obtained following surgery or at necropsy in 4 of these cases. No abnormality was found on 2DE in the other 23 patients. All acoustically dense thrombi were larger than 1.5 cm and had some degree of organisation. Two were recent, histologically showing red blood cells and mplatelet-fibrin columnation. The accoustical similarity of small thrombi to the surrounding blood or endocardium may hinder the sensitivity of the method.The technique may help to define patients at risk from embolisation. As intracardiac thrombi are a common and potentially an easily prevented cause of stroke,a 2DE screen should be undertaken in patients with arrhythmias or clinical evidence of cardiac disease who have experienced one or more episodes of cerebral ischaemia.

Hyaluronan affects extravascular water in lungs of unanesthetized rabbits

1989 ◽  
Vol 66 (6) ◽  
pp. 2595-2599 ◽  
Author(s):  
J. Bhattacharya ◽  
T. Cruz ◽  
S. Bhattacharya ◽  
B. A. Bray
Keyword(s):  
Body Weight ◽  
Water Content ◽  
Extravascular Lung Water ◽  
Volume Expansion ◽  
The Other ◽  
Lung Water ◽  
Intravenous Saline ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

We have determined whether changes in lung hyaluronan content affect extravascular water in lungs of unanesthetized rabbits. Three groups of experiments were performed. In group 1 (n = 12), no infusions were given; in group 2, nine pairs of rabbits received either intravenous hyaluronidase (750 U.kg-1.min-1) or an equivalent volume of saline; in group 3, nine pairs of rabbits received either hyaluronidase or saline, followed by intravenous saline infusion amounting to 24% of body weight. At the end of each experiment, one lung was analyzed for extravascular lung water by the wet-dry method. Except for group 3, in all animals the other lung was analyzed for hyaluronan content by a method that involved hydrolyzing lung hyaluronan with fungal hyaluronidase to release reducing N-acetyl glucosamine groups, which were quantified. In group 1, lung hyaluronan, which varied from 50 to 159 micrograms/g dry wt (mean 106 +/- 35 micrograms/g dry wt), significantly correlated with variation in extravascular lung water (mean 4.2 +/- 0.3 g/g dry wt). In group 2 rabbits given hyaluronidase, lung hyaluronan was 40% lower and extravascular lung water was 14.6% lower than in paired controls (P less than 0.01). In group 3, volume expansion did not affect lung water, except after hyaluronidase when lung water was 47% higher than paired controls. We conclude that in the lung the content of hyaluronan is one of the determinants of extravascular water content.

An Anglo-Saxon Disc Brooch from Northamptonshire

1962 ◽  
Vol 42 (1) ◽  
pp. 53-56
Author(s):  
Vera I. Evison
Keyword(s):  
The Body ◽  
The Other ◽  
Anglo Saxon ◽  
Disc Diameter ◽  
Thin Disc ◽  
Lower Jaw ◽  
Upper Jaw

A small gilt-bronze disc brooch was found at Little Houghton, Northants., in 1957, a surface find on a Roman site, and was acquired by Northampton Museum (pl. xv b, fig. 1). It is a thin disc, diameter 2·5 cm., tapering at the border, with remains of pin holder and catch at the back and shallow pattern in relief on the front. The gilding has rubbed off the higher parts of the pattern, and has disappeared entirely in places where the brooch has been damaged and bent, possibly by fire. The ornament consists of two Style II animals, identical except for the shape of the jaw. They are S-shaped, turning round to bite their own backs; the body continues directly into the angle of a back leg which crosses the body and ends at the border in the rudiments of a foot; a front limb shoots forward to interlock with the hind curve of the other animal; the head is an eye framed by a right-angle; in one case the upper jaw passes below the body and the lower jaw is short and curves only slightly outwards; in the other the upper jaw again runs below the body, and the lower jaw swings round and seems to meet the upper jaw behind in a complete loop. There is damage at this point, however, and on analogous evidence it is quite likely that the lower jaw did not join the upper, but swept on independently.

scholarly journals Evaluation of the concentration of malondialdehyde and nitrite in patients with sickle cell anemia treated or not with hydroxyurea

2010 ◽  
Vol 8 (4) ◽  
pp. 414-418 ◽  
Author(s):  
Darcielle Bruna Dias Elias ◽  
Rivelilson Mendes de Freitas ◽  
Romélia Pinheiro Gonçalves ◽  
Hemerson Yuri Ferreira Magalhães ◽  
Jacqueline Holanda de Sousa ◽  
...  
Keyword(s):  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Serum Levels ◽  
The Other ◽  
Control Group ◽  
Clinical Variables ◽  
Short Period ◽  
Significant Difference ◽  
Group 2 ◽  
Group 1

ABSTRACT Objective: To determine the serum levels of malondialdehyde and nitrite in patients with sickle cell anemia treated or not with hydroxyurea in outpatient's setting. Methods: Of the 65 patients with sickle cell anemia selected for the study, 51 were not treated with hydroxyurea (Group 1), 14 made chronic use of hydroxyurea (Group 2) and 20 individuals had no hemoglobinopathies (Control Group). Results: The Control Group had a lower and more homogeneous concentration of malondialdehyde levels as compared to the other groups. The results of Groups 1 and 2 showed increased values of malondialdehyde levels when compared to the Control Group. Considering the values of Groups 1 and 2, there were no significant changes in the malondialdehyde levels. There was no significant difference in the serum levels of nitrite between the groups. Group 2 presented a statistically significant correlation between serum malondialdehyde levels and the clinical variables investigated. In turn, Group 1 showed correlation only with occurrence of three or more vaso-occlusive crises. There was no correlation between nitrite levels and the clinical variables. Conclusion: The results revealed that during the pathogenesis of sickle cell anemia, an increase in lipid peroxidation was observed. On the other hand, no changes in oxidative parameters were detected during treatment with hydroxyurea, probably due to the short period of treatment of the patients studied.

Effects of crossbred ewe genotype and ram genotype on ewe prolificacy, lamb viability and lamb output in the lowland sector

2002 ◽  
Vol 139 (2) ◽  
pp. 169-181 ◽  
Author(s):  
L. E. R. DAWSON ◽  
A. F. CARSON
Keyword(s):  
Growth Rate ◽  
Northern Ireland ◽  
Growth Rates ◽  
Genetic Improvement ◽  
Live Weight ◽  
Growth Index ◽  
The Other ◽  
Lean Growth ◽  
And Control ◽  
Lamb Growth

A study was carried out on five lowland farms in Northern Ireland over 3 years to investigate the effect of crossbred ewe and ram genotype on ewe prolificacy, lamb viability and weaned lamb output. Four crossbred ewe genotypes were sourced from six hill farms involved in a previous study – Bluefaced Leicester×Blackface (BLXB), Texel×Blackface (TXB), Suffolk×Cheviot (SXCH) and Texel×Cheviot (TXCH). On each farm, groups of 20–30 of each crossbred ewe genotype were mated with Suffolk or Texel rams. Throughout the 3 years of the study, the ewe genotypes lambed at 1, 2 and 3 years of age. Within each of the ram breeds, high lean growth index rams sourced from UK sire reference schemes were compared with rams sourced from flocks not involved in objective genetic improvement programmes (control). BLXB ewes were the most prolific of the four ewe genotypes producing 1.73 lambs per ewe lambed compared with 1.47 for TXB, 1.46 for SXCH and 1.41 for TXCH (P<0.001). Lamb mortality was similar for the four ewe genotypes, thus number of lambs weaned was greatest for the BLXB ewes (P<0.001) with the other three crosses producing similar numbers of lambs. A greater proportion (P<0.05) of SXCH ewes lambed without assistance compared with BLXB and TXB ewes and a greater proportion of TXCH ewes had abundant supplies of colostrum compared with the other crosses (P<0.10). Output of weaned lamb per ewe lambed and per ewe metabolic live weight (P<0.001) was greatest in the BLXB ewes. Ewe productivity, prolificacy, number of lambs weaned and the proportion of ewes lambing without assistance increased with ewe age (P<0.001). Lamb growth rate from birth to 6 weeks and from birth to weaning increased with ewe age (P<0.05). Crossbred ewes lambing at 3 years old had a greater output of weaned lamb compared with ewes lambing at 1 and 2 years old (P<0.001). Ram genotype had no effect on ewe prolificacy, lamb viability or pre-weaning growth rates, although Texel-sired lambs had lower birth weights than Suffolk-sired lambs and control-sired lambs had lower birth weights than high lean index-sired lambs (P<0.05).

scholarly journals The Effects of Norepinephrine Infusion on the Circulating Lymphocyte Counts of Post–Open Heart Surgery Patients

2000 ◽  
Vol 1 (3) ◽  
pp. 199-209
Author(s):  
Wanda Zziwambazza ◽  
Carrie J. Merkle ◽  
Ida M. Moore ◽  
Jean Davis
Keyword(s):  
Heart Surgery ◽  
Open Heart Surgery ◽  
The Other ◽  
Open Heart ◽  
Postoperative Infections ◽  
Norepinephrine Infusion ◽  
Beta Blocking ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

In this retrospective study employing chart reviews, 75 open heart surgery patients (OHSPs) were divided into 3 groups of 25 patients. Group 1 received no intravenous (IV) norepinephrine (NE) after surgery. Group 2 and group 3 received a minimum of 0.028 mcg/kg/min of IV NE for 6-24 h and greater than 24 h, respectively. In the 3 groups, preoperative lymphocyte counts were compared to counts obtained on postoperative days 1 and 2. The results showed lower lymphocyte counts on postoperative day 2 in group 3 subjects, who received NE for 24 h or more, compared to subjects of the other groups who received no NE or 6-24 h of NE (p < 0.05). There was also evidence that preoperative use of beta-blocking agents significantly affected the change in lymphocyte counts from day 1 to day 2 in both groups receiving NE. Furthermore, postoperative infections were more prevalent in group 3 than the other 2 groups (p < 0.05). The lower lymphocyte counts and higher infection rate, however, may be linked to lower postoperative blood pressure and increased number of intensive care unit days in group 3. Further investigation is warranted to elucidate the effects of IV NE administration on the lymphocyte counts of OHSPs and to reduce infections in those receiving NE.

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