On large-amplitude pulsating fountains

1998 ◽  
Vol 366 ◽  
pp. 333-350 ◽  
Author(s):  
CHRISTOPHE CLANET
Keyword(s):  
Surface Tension ◽  
Large Amplitude ◽  
Characteristic Frequency ◽  
Oscillatory Regime ◽  
Hydrodynamic Properties ◽  
Capillary Length ◽  
Wide Range ◽  
The Stability ◽  
Existing Data ◽  
Good Agreement

We study the behaviour of an upward vertical water jet of density, ρ, and surface tension, σ, injected through a tube of diameter, D, with a momentum-averaged velocity, V. These fountains are shown to exhibit large-amplitude oscillations in the range 0.1[les ]D/a[les ]1.6, and 20[les ]V2/(gD)[les ]400, where g is the acceleration due to gravity and a is the capillary length, a≡(2σ/(ρg))1/2. The characteristic frequency of the oscillations, f, and their limits of existence are studied experimentally. A model is developed, leading to the expression for the frequency:formula hereThis expression is shown to be in good agreement with existing data and with new measurements, conducted over a wide range of Bond (Bo≡D/a) and Froude (Fr≡V2/gD) numbers. The stability of the model is considered and the limits of the oscillatory regime are related to the hydrodynamic properties of the flow.

Stability and collapse of holes in liquid layers

2018 ◽  
Vol 855 ◽  
pp. 1130-1155 ◽  
Author(s):  
Cunjing Lv ◽  
Michael Eigenbrod ◽  
Steffen Hardt
Keyword(s):  
Liquid Film ◽  
Power Laws ◽  
Theoretical Models ◽  
Liquid Volume ◽  
Capillary Length ◽  
Minimum Thickness ◽  
The Stability ◽  
Film Profile ◽  
Hole Closure ◽  
Good Agreement

We investigate experimentally and theoretically the stability and collapse of holes in liquid layers on bounded substrates with various wettabilities. It is shown that for a liquid layer with a thickness of the order of the capillary length, a stable hole exists when the hole diameter is bigger than a critical value $d_{c}$. Consequently, a further increase of the liquid volume causes the hole to collapse. It is found that$d_{c}$increases with the size of the container, but its dependence on the contact angle is very weak. The experimental results are compared with theory, and good agreement is obtained. Moreover, we present investigations of the dynamics of the hole and the evolution of the liquid film profile after the collapse. The diameter of the hole during collapse and the minimum thickness of the liquid film shortly after the collapse obey different power laws with time. Simple theoretical models are developed which indicate that the collapse of the hole is triggered by surface tension and the subsequent closure process results from inertia, whereas the growth of the liquid column after hole closure results from the balance between the capillary force and inertia. Corresponding scaling coefficients are determined.

Lattice-Dynamical Estimation of Atomic Displacement Parameters in Carbonates: Calcite and Aragonite CaCO3, Dolomite CaMg(CO3)2 and Magnesite MgCO3

1998 ◽  
Vol 54 (5) ◽  
pp. 515-523 ◽  
Author(s):  
T. Pilati ◽  
F. Demartin ◽  
C. M. Gramaccioli
Keyword(s):  
Structure Refinement ◽  
Atomic Displacement ◽  
Empirical Potentials ◽  
Wide Range ◽  
Anisotropic Displacement Parameters ◽  
The Stability ◽  
Experimental Values ◽  
Atomic Displacement Parameters ◽  
Good Agreement ◽  
Raman And Ir Spectra

Using crystallographic information and empirical potentials derived from fitting the vibrational frequencies of all the substances under study, together with those of a group of silicates and oxides, a Born–von Karman rigid-ion lattice-dynamical model has been applied to the whole Brillouin zone in calcite, aragonite (α- and β-CaCO3, respectively), magnesite (MgCO3) and dolomite [CaMg(CO3)2]. The Raman and IR spectra are satisfactorily reproduced and interpreted by these calculations; there is also very good agreement with atomic anisotropic displacement parameters (a.d.p.'s) derived from accurate crystal structure refinement by various authors and with the experimental values of thermodynamic functions over a wide range of temperatures. On these vibrational grounds, the stability of calcite with respect to aragonite at high temperature can be accounted for.

AB-INITIO STUDY OF VARIOUS PROPERTIES OF SMALL DIAMETER ARMCHAIR CARBON NANOTUBES

2005 ◽  
Vol 04 (03) ◽  
pp. 295-303
Author(s):  
B. K. AGRAWAL ◽  
S. AGRAWAL ◽  
S. SINGH ◽  
R. SRIVASTAVA
Keyword(s):  
Carbon Nanotubes ◽  
Ab Initio ◽  
Small Diameter ◽  
Radial Breathing Mode ◽  
Binding Energies ◽  
Wide Range ◽  
Optical Matrix Element ◽  
The Stability ◽  
Semiconducting Nanotubes ◽  
Good Agreement

A comprehensive ab-initio investigation of the stability, structural, electronic, optical and Raman-active properties has been performed for the small diameter armchair carbon nanotubes. A number of new features not discussed earlier are observed in the present study. The binding energies (BEs) for the ultrathin nanotubes with respect to the graphine sheet are negative and the magnitude of the negative BE decreases with the diameter of the tube approaching zero for the graphine sheet. The separation between the two van Hove singularities (vHs) around the Fermi level increases with the diameter of the tube. The main absorption arises from the transitions between the states at nonzero values of kz lying in the range 0.38–0.50. There is a large variation in the magnitude of the optical matrix-element with the wave vector. The energy range of the strong optical absorption increases with the diameter of the tube. The presently predicted absorption and the RBM frequencies are in good agreement with the available experimental data. The variation of the radial breathing mode (RBM) frequency with diameter "d" of a tube obeys a relation which is very close to an experimentally determined relation obtained for a number of wide semiconducting nanotubes possessing a wide range of chiral angles.

Analysis and Preliminary Design of a Sailboat with Self-Trimming Wing Sail

1983 ◽  
Vol 20 (04) ◽  
pp. 370-376
Author(s):  
B. G. Newman ◽  
G. I. Fekete
Keyword(s):  
Reynolds Number ◽  
Wind Tunnel ◽  
Preliminary Design ◽  
Static And Dynamic Stability ◽  
Flap Deflection ◽  
The Stability ◽  
Lift And Drag ◽  
Existing Data ◽  
Good Agreement ◽  
Rigid Wing

A theoretical analysis has been made of the static and dynamic stability of a self-trimming rigid wing sail for use on a sailboat without sheets or halyards. The effects of camber or flap deflection and the position of the trimming plane are considered. A satisfactory design incorporates an uncambered main wing of medium aspect ratio and a trimming tail plane. Wind tunnel tests on a model of this design confirmed the stability of the sail and indicated adequate damping. The measured lift and drag coefficients were in good agreement with existing data at a similar Reynolds number.

Performance of Electronic Structure Methods for the Description of Hückel-Möbius Interconversions in Extended π-Systems

2019 ◽  
Author(s):  
Tatiana Woller ◽  
Ambar Banerjee ◽  
Nitai Sylvetsky ◽  
Xavier Deraet ◽  
Frank De Proft ◽  
...  
Keyword(s):  
Electronic Structure ◽  
Basis Set ◽  
Dft Methods ◽  
Molecular Switching ◽  
Wide Range ◽  
Electronic Structure Methods ◽  
Explicitly Correlated ◽  
Relative Errors ◽  
The Stability ◽  
Basis Set Expansion

<p>Expanded porphyrins provide a versatile route to molecular switching devices due to their ability to shift between several π-conjugation topologies encoding distinct properties. Taking into account its size and huge conformational flexibility, DFT remains the workhorse for modeling such extended macrocycles. Nevertheless, the stability of Hückel and Möbius conformers depends on a complex interplay of different factors, such as hydrogen bonding, p···p stacking, steric effects, ring strain and electron delocalization. As a consequence, the selection of an exchange-correlation functional for describing the energy profile of topological switches is very difficult. For these reasons, we have examined the performance of a variety of wavefunction methods and density functionals for describing the thermochemistry and kinetics of topology interconversions across a wide range of macrocycles. Especially for hexa- and heptaphyrins, the Möbius structures have a pronouncedly stronger degree of static correlation than the Hückel and figure-eight structures, and as a result the relative energies of singly-twisted structures are a challenging test for electronic structure methods. Comparison of limited orbital space full CI calculations with CCSD(T) calculations within the same active spaces shows that post-CCSD(T) correlation contributions to relative energies are very minor. At the same time, relative energies are weakly sensitive to further basis set expansion, as proven by the minor energy differences between MP2/cc-pVDZ and explicitly correlated MP2-F12/cc-pVDZ-F12 calculations. Hence, our CCSD(T) reference values are reasonably well-converged in both 1-particle and n-particle spaces. While conventional MP2 and MP3 yield very poor results, SCS-MP2 and particularly SOS-MP2 and SCS-MP3 agree to better than 1 kcal mol<sup>-1</sup> with the CCSD(T) relative energies. Regarding DFT methods, only M06-2X provides relative errors close to chemical accuracy with a RMSD of 1.2 kcal mol<sup>-1</sup>. While the original DSD-PBEP86 double hybrid performs fairly poorly for these extended p-systems, the errors drop down to 2 kcal mol<sup>-1</sup> for the revised revDSD-PBEP86-NL, again showing that same-spin MP2-like correlation has a detrimental impact on performance like the SOS-MP2 results. </p>

Insights into Potent Therapeutical Antileukemic Agent L-glutaminase Enzyme Under Solid-state Fermentation: A Review

2020 ◽  
Vol 21 (3) ◽  
pp. 211-220 ◽  
Author(s):  
Chandrasai Potla Durthi ◽  
Madhuri Pola ◽  
Satish Babu Rajulapati ◽  
Anand Kishore Kola
Keyword(s):  
Solid State ◽  
Solid State Fermentation ◽  
Food Industry ◽  
Energy Requirement ◽  
Production Studies ◽  
Wide Range ◽  
Hybridoma Technology ◽  
Bacteria And Fungi ◽  
The Stability ◽  
Glutaminase Activity

Aim & objective: To review the applications and production studies of reported antileukemic drug L-glutaminase under Solid-state Fermentation (SSF). Overview: An amidohydrolase that gained economic importance because of its wide range of applications in the pharmaceutical industry, as well as the food industry, is L-glutaminase. The medical applications utilized it as an anti-tumor agent as well as an antiretroviral agent. L-glutaminase is employed in the food industry as an acrylamide degradation agent, as a flavor enhancer and for the synthesis of theanine. Another application includes its use in hybridoma technology as a biosensing agent. Because of its diverse applications, scientists are now focusing on enhancing the production and optimization of L-glutaminase from various sources by both Solid-state Fermentation (SSF) and submerged fermentation studies. Of both types of fermentation processes, SSF has gained importance because of its minimal cost and energy requirement. L-glutaminase can be produced by SSF from both bacteria and fungi. Single-factor studies, as well as multi-level optimization studies, were employed to enhance L-glutaminase production. It was concluded that L-glutaminase activity achieved by SSF was 1690 U/g using wheat bran and Bengal gram husk by applying feed-forward artificial neural network and genetic algorithm. The highest L-glutaminase activity achieved under SSF was 3300 U/gds from Bacillus sp., by mixture design. Purification and kinetics studies were also reported to find the molecular weight as well as the stability of L-glutaminase. Conclusion: The current review is focused on the production of L-glutaminase by SSF from both bacteria and fungi. It was concluded from reported literature that optimization studies enhanced L-glutaminase production. Researchers have also confirmed antileukemic and anti-tumor properties of the purified L-glutaminase on various cell lines.

scholarly journals Separate Universe calibration of the dependence of halo bias on cosmic web anisotropy

2020 ◽  
Vol 499 (3) ◽  
pp. 4418-4431 ◽  
Author(s):  
Sujatha Ramakrishnan ◽  
Aseem Paranjape
Keyword(s):  
Dark Matter ◽  
High Precision ◽  
Gaussian Distribution ◽  
Initial Perturbation ◽  
Analytical Framework ◽  
Web Environment ◽  
Wide Range ◽  
Galaxy Assembly ◽  
Very High ◽  
Good Agreement

ABSTRACT We use the Separate Universe technique to calibrate the dependence of linear and quadratic halo bias b1 and b2 on the local cosmic web environment of dark matter haloes. We do this by measuring the response of halo abundances at fixed mass and cosmic web tidal anisotropy α to an infinite wavelength initial perturbation. We augment our measurements with an analytical framework developed in earlier work that exploits the near-lognormal shape of the distribution of α and results in very high precision calibrations. We present convenient fitting functions for the dependence of b1 and b2 on α over a wide range of halo mass for redshifts 0 ≤ z ≤ 1. Our calibration of b2(α) is the first demonstration to date of the dependence of non-linear bias on the local web environment. Motivated by previous results that showed that α is the primary indicator of halo assembly bias for a number of halo properties beyond halo mass, we then extend our analytical framework to accommodate the dependence of b1 and b2 on any such secondary property that has, or can be monotonically transformed to have, a Gaussian distribution. We demonstrate this technique for the specific case of halo concentration, finding good agreement with previous results. Our calibrations will be useful for a variety of halo model analyses focusing on galaxy assembly bias, as well as analytical forecasts of the potential for using α as a segregating variable in multitracer analyses.

scholarly journals mtDNAcombine: tools to combine sequences from multiple studies

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Eleanor F. Miller ◽  
Andrea Manica
Keyword(s):  
Sequence Data ◽  
Data Extraction ◽  
Bayesian Skyline Plot ◽  
Model Organisms ◽  
Data Sets ◽  
Data Handling ◽  
Online Database ◽  
Genetic Studies ◽  
Wide Range ◽  
Existing Data

Abstract Background Today an unprecedented amount of genetic sequence data is stored in publicly available repositories. For decades now, mitochondrial DNA (mtDNA) has been the workhorse of genetic studies, and as a result, there is a large volume of mtDNA data available in these repositories for a wide range of species. Indeed, whilst whole genome sequencing is an exciting prospect for the future, for most non-model organisms’ classical markers such as mtDNA remain widely used. By compiling existing data from multiple original studies, it is possible to build powerful new datasets capable of exploring many questions in ecology, evolution and conservation biology. One key question that these data can help inform is what happened in a species’ demographic past. However, compiling data in this manner is not trivial, there are many complexities associated with data extraction, data quality and data handling. Results Here we present the mtDNAcombine package, a collection of tools developed to manage some of the major decisions associated with handling multi-study sequence data with a particular focus on preparing sequence data for Bayesian skyline plot demographic reconstructions. Conclusions There is now more genetic information available than ever before and large meta-data sets offer great opportunities to explore new and exciting avenues of research. However, compiling multi-study datasets still remains a technically challenging prospect. The mtDNAcombine package provides a pipeline to streamline the process of downloading, curating, and analysing sequence data, guiding the process of compiling data sets from the online database GenBank.

scholarly journals A pH-Responsive Foam Formulated with PAA/Gemini 12-2-12 Complexes

2021 ◽  
Vol 5 (3) ◽  
pp. 37
Author(s):  
Hernán Martinelli ◽  
Claudia Domínguez ◽  
Marcos Fernández Leyes ◽  
Sergio Moya ◽  
Hernán Ritacco
Keyword(s):  
Surface Tension ◽  
Dynamic Surface Tension ◽  
Foam Formation ◽  
Ph Responsive ◽  
Dynamic Surface ◽  
X Ray ◽  
Equilibrium Surface Tension ◽  
Potential Applications ◽  
The Stability ◽  
Air Interfaces

In the search for responsive complexes with potential applications in the formulation of smart dispersed systems such as foams, we hypothesized that a pH-responsive system could be formulated with polyacrylic acid (PAA) mixed with a cationic surfactant, Gemini 12-2-12 (G12). We studied PAA-G12 complexes at liquid–air interfaces by equilibrium and dynamic surface tension, surface rheology, and X-ray reflectometry (XRR). We found that complexes adsorb at the interfaces synergistically, lowering the equilibrium surface tension at surfactant concentrations well below the critical micelle concentration (cmc) of the surfactant. We studied the stability of foams formulated with the complexes as a function of pH. The foams respond reversibly to pH changes: at pH 3.5, they are very stable; at pH > 6, the complexes do not form foams at all. The data presented here demonstrate that foam formation and its pH responsiveness are due to interfacial dynamics.

scholarly journals Polymer-Drug Conjugates as Nanotheranostic Agents

2021 ◽  
Vol 2 (1) ◽  
pp. 63-81
Author(s):  
Sajana Manandhar ◽  
Erica Sjöholm ◽  
Johan Bobacka ◽  
Jessica M. Rosenholm ◽  
Kuldeep K. Bansal
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Treatment Options ◽  
The Body ◽  
Drug Conjugates ◽  
Imaging Characteristics ◽  
Wide Range ◽  
Systemic Side Effects ◽  
Theranostic Agents ◽  
The Stability

Since the last decade, the polymer-drug conjugate (PDC) approach has emerged as one of the most promising drug-delivery technologies owing to several benefits like circumventing premature drug release, offering controlled and targeted drug delivery, improving the stability, safety, and kinetics of conjugated drugs, and so forth. In recent years, PDC technology has advanced with the objective to further enhance the treatment outcomes by integrating nanotechnology and multifunctional characteristics into these systems. One such development is the ability of PDCs to act as theranostic agents, permitting simultaneous diagnosis and treatment options. Theranostic nanocarriers offer the opportunity to track the distribution of PDCs within the body and help to localize the diseased site. This characteristic is of particular interest, especially among those therapeutic approaches where external stimuli are supposed to be applied for abrupt drug release at the target site for localized delivery to avoid systemic side effects (e.g., Visudyne®). Thus, with the help of this review article, we are presenting the most recent updates in the domain of PDCs as nanotheranostic agents. Different methodologies utilized to design PDCs along with imaging characteristics and their applicability in a wide range of diseases, have been summarized in this article.

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