Further Analysis of Near Eastern Obsidians

1969 ◽  
Vol 34 ◽  
pp. 319-331 ◽  
Author(s):  
Colin Renfrew ◽  
J. E. Dixon ◽  
J. R. Cann
Keyword(s):  
Early Neolithic ◽  
Near Eastern ◽  
New Information ◽  
Trading Mechanisms ◽  
Trading Pattern ◽  
Definition Of ◽  
Prehistoric Trade ◽  
New Evidence ◽  
Obsidian Source ◽  
Insight Into

The very early development and extent of the obsidian trade in the Near East is being increasingly documented by the discovery and excavation of Early Neolithic sites throughout the area. Since the publication of our last paper (Renfrew, Cann and Dixon, 1966), obsidians from five aceramic Neolithic sites have been analysed, and the natural source of the material determined in each case. All the results fall into the framework of groups already established. In addition, one new obsidian source has been discovered.This confirmation of the characterizations hitherto achieved is satisfactory, but perhaps more important is the new evidence for the reconstruction of the pattern of the trade or traffic in obsidian in Early Neolithic times. Regularities in this pattern are becoming apparent, which allow a greater insight into the trading mechanisms involved.In this paper, written by Colin Renfrew on the basis of analyses and group divisions by J. E. Dixon and J. R. Cann, new information concerning the Anatolian sources is first considered, and new results for the Early Neolithic and later obsidians discussed. In the last section, an attempt is made at the more precise definition of the obsidian trading pattern in the 7th and 6th millennia B.C. on the basis of a more detailed analysis of the prehistoric trade statistics.

scholarly journals The Neolithic Site of Serra Cicora: Results of the AMS Radiocarbon Dating

Radiocarbon ◽  
2005 ◽  
Vol 47 (2) ◽  
pp. 207-210 ◽  
Author(s):  
G Quarta ◽  
M D'Elia ◽  
E Ingravallo ◽  
I Tiberi ◽  
L Calcagnile
Keyword(s):  
Mass Spectrometry ◽  
Radiocarbon Dating ◽  
Southern Italy ◽  
Early Neolithic ◽  
Human Occupation ◽  
Late Neolithic ◽  
Ams Radiocarbon Dating ◽  
Neolithic Site ◽  
New Information ◽  
Definition Of

Bone and charcoal samples from the Neolithic site of Serra Cicora in the Salento Peninsula (southern Italy) have been dated by accelerator mass spectrometry (AMS). Measurements appear to support other archaeological evidence and have shown that 2 distinct phases of human occupation of the site can be identified: the first occupation in the Early Neolithic and a second occupation in the Middle-Late Neolithic. The results provide new information and are a fundamental contribution to the definition of the absolute chronology of the Middle-Late Neolithic in this part of Europe.

Aleksey Peshkov as an editor of Samarskaya Gazeta

2020 ◽  
pp. 128-138
Author(s):  
A. S. Bik-Bulatov
Keyword(s):  
Local History ◽  
Organizational Skills ◽  
First Time ◽  
New Evidence ◽  
Insight Into ◽  
Shed Light

The article uses little known letters of M. Gorky, many of which were published for the first time in 1997, as well as findings of Samara-based experts in local history to shed light on the writer’s work as editor-in-chief of the Samarskaya Gazeta newspaper in 1895. The researcher introduces hitherto unstudied reminiscences of the journalist D. Linyov (Dalin) about this period, which reference a letter by Gorky, now lost. The paper details a newly discovered episode of Gorky’s professional biography as a journalist: it concerns his campaign against a Samara ‘she-wolf,’ the madam of a local brothel A. Neucheva. Linyov’s reminiscences turn out to be an important and interesting source, offering an insight into the daily grind of the young editor Gorky, providing new evidence of his excellent organizational skills, and describing his moral and social stance. The author presents his work in the context of a recently initiated broader discussion about the need to map out all Russian periodicals for the period until 1917, as well as all research devoted to individual publications.

Small rodent communities (Muridae) in Gabonese savannas: species diversity and biogeographical affinities

Mammalia ◽  
2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Jean-François Mboumba ◽  
Maxime R. Hervé ◽  
Véronique Guyot ◽  
Frederic Ysnel
Keyword(s):  
Ecological Factors ◽  
Abundant Species ◽  
Small Rodent ◽  
Small Rodents ◽  
South West ◽  
New Information ◽  
Different Types ◽  
Mus Minutoides ◽  
Insight Into ◽  
Coastal Basin

Abstract The study contributes to the knowledge of species composition and biogeographical affinities of savannas rodent in Gabon. Unlike small rodents in Gabonese forests, there is little data on the diversity of small rodents in Gabonese savannas. The diversity and distribution of rodent murid communities was studied in four different types of savanna in Gabon: Coastal Basin (South-West), Lopé/Okanda (in the Center), Batéké Plateaux (Southeastern) and Ngougnié/ N’yanga (in the South). A total of 428 individuals representing six species were captured over 11,920 trap nights. Trap success was highly variable (2.2–6.9 %). The most abundant species were Mus minutoides (69%) followed by Lemniscomys striatus (21.5%). Indices of species richness varied from 2 to 5 and diversity (Shannon and Weaver) was low in the four savannas with the highest value at Ngougnié/N’yanga (H′ = 1.2). Species distributions show that Gabonese savanna small rodents conform to four distribution types, with one species known from Zambesian savannas exhibiting austral affinities (Pelomys campanae: occurs in three southern savannas). This new information provides important insight into the biogeography of small rodents at a local and regional level. Moreover, the correspondence analysis highlighted an influence of local ecological factors on population abundance.

scholarly journals Lopinavir and Nelfinavir Induce the Accumulation of Crystalloid Lipid Inclusions within the Reservosomes of Trypanosoma cruzi and Inhibit Both Aspartyl-Type Peptidase and Cruzipain Activities Detected in These Crucial Organelles

2021 ◽  
Vol 6 (3) ◽  
pp. 120
Author(s):  
Leandro S. Sangenito ◽  
Miria G. Pereira ◽  
Thais Souto-Padron ◽  
Marta H. Branquinha ◽  
André L. S. Santos
Keyword(s):  
Trypanosoma Cruzi ◽  
Opportunistic Infections ◽  
Lipid Inclusion ◽  
Transmission Electron ◽  
New Information ◽  
Lipid Inclusions ◽  
Immunodeficiency Virus ◽  
Parasite Viability ◽  
Aspartyl Peptidases ◽  
New Evidence

Several research groups have explored the repositioning of human immunodeficiency virus aspartyl peptidase inhibitors (HIV-PIs) on opportunistic infections caused by bacteria, fungi and protozoa. In Trypanosoma cruzi, HIV-PIs have a high impact on parasite viability, and one of the main alterations promoted by this treatment is the imbalance in the parasite’s lipid metabolism. However, the reasons behind this phenomenon are unknown. In the present work, we observed by transmission electron microscopy (TEM) that the treatment of T. cruzi epimastigotes with the HIV-PIs lopinavir and nelfinavir induced a huge accumulation of crystalloid-shaped lipids within the reservosomes, most of them deforming these key organelles. As previously reported, those structures are characteristic of lipid inclusions formed mostly of cholesterol and cholesterol-esters. The fractionation of nontreated epimastigotes generated two distinct fractions enriched in reservosomes: one mostly composed of lipid inclusion-containing reservosomes (Fraction B1) and one where lipid inclusions were much less abundant (Fraction B2). Interestingly, the extract of Fraction B2 presented enzymatic activity related to aspartyl-type peptidases 3.5 times higher than that found in the extract obtained from Fraction B1. The cleavage of cathepsin D substrate by this class of peptidases was strongly impaired by pepstatin A, a prototypical aspartyl PI, and the HIV-PIs lopinavir and nelfinavir. In addition, both HIV-PIs also inhibited (to a lesser extent) the cruzipain activity present in reservosomes. Finally, our work provides new evidence concerning the presence and supposed participation of aspartyl peptidases in T. cruzi, even as it adds new information about the mechanisms behind the alterations promoted by lopinavir and nelfinavir in the protozoan.

scholarly journals Conceptual and Practical Issues in the Pharmacological Treatment of Brain Injury

1993 ◽  
Vol 4 (3) ◽  
pp. 227-237 ◽  
Author(s):  
Donald G. Stein ◽  
Marylou M. Glasier ◽  
Stuart W. Hoffman
Keyword(s):  
Central Nervous System ◽  
Brain Injury ◽  
Time Course ◽  
Chemical Activity ◽  
Behavioral Testing ◽  
Naturally Occurring ◽  
New Information ◽  
Definition Of ◽  
Injury And Repair ◽  
The Brain

It is only within the last ten years that research on treatment for central nervous system (CNS) recovery after injury has become more focused on the complexities involved in promoting recovery from brain injury when the CNS is viewed as an integrated and dynamic system. There have been major advances in research in recovery over the last decade, including new information on the mechanics and genetics of metabolism and chemical activity, the definition of excitotoxic effects and the discovery that the brain itself secretes complex proteins, peptides and hormones which are capable of directly stimulating the repair of damaged neurons or blocking some of the degenerative processes caused by the injury cascade. Many of these agents, plus other nontoxic naturally occurring substances, are being tested as treatment for brain injury. Further work is needed to determine appropriate combinations of treatments and optimum times of administration with respect to the time course of the CNS disorder. In order to understand the mechanisms that mediate traumatic brain injury and repair, there must be a merging of findings from neurochemical studies with data from intensive behavioral testing.

scholarly journals The history of settlement and agrarian land use in a boreal forest in Värmland, Sweden, new evidence from pollen analysis

2021 ◽  
Author(s):  
Sigrún Dögg Eddudóttir ◽  
Eva Svensson ◽  
Stefan Nilsson ◽  
Anneli Ekblom ◽  
Karl-Johan Lindholm ◽  
...  
Keyword(s):  
Land Use ◽  
Pollen Analysis ◽  
Large Scale ◽  
Pollen Grains ◽  
Ice Age ◽  
Valuable Insight ◽  
Archaeological Survey ◽  
History Of ◽  
New Evidence ◽  
Insight Into

AbstractShielings are the historically known form of transhumance in Scandinavia, where livestock were moved from the farmstead to sites in the outlands for summer grazing. Pollen analysis has provided a valuable insight into the history of shielings. This paper presents a vegetation reconstruction and archaeological survey from the shieling Kårebolssätern in northern Värmland, western Sweden, a renovated shieling that is still operating today. The first evidence of human activities in the area near Kårebolssätern are Hordeum- and Cannabis-type pollen grains occurring from ca. 100 bc. Further signs of human impact are charcoal and sporadic occurrences of apophyte pollen from ca. ad 250 and pollen indicating opening of the canopy ca. ad 570, probably a result of modification of the forest for grazing. A decrease in land use is seen between ad 1000 and 1250, possibly in response to a shift in emphasis towards large scale commodity production in the outlands. Emphasis on bloomery iron production and pitfall hunting may have caused a shift from agrarian shieling activity. The clearest changes in the pollen assemblage indicating grazing and cultivation occur from the mid-thirteenth century, coinciding with wetter climate at the beginning of the Little Ice Age. The earliest occurrences of anthropochores in the record predate those of other shieling sites in Sweden. The pollen analysis reveals evidence of land use that predates the results of the archaeological survey. The study highlights how pollen analysis can reveal vegetation changes where early archaeological remains are obscure.

Root cause analysis of rattle noise in twin-tube vehicle dampers

2021 ◽  
pp. 095440702110652
Author(s):  
Marian Sikora ◽  
Janusz Gołdasz
Keyword(s):  
Design Of Experiment ◽  
Ride Comfort ◽  
Design Parameters ◽  
Vehicle Suspension ◽  
Experiment Study ◽  
Cause Analysis ◽  
Root Cause ◽  
Main Effect ◽  
Definition Of ◽  
Insight Into

The aim of this work is to provide an insight into the rattle noise phenomena occurring in double-tube (twin-tube) vehicle suspension dampers. In the dampers the particular phenomenon results from interactions between the valve(s) and the fluid passing through them. The rattling noise phenomena is known to degrade the vehicle passenger’s perception of ride comfort as well as to influence the performance of the dampers at low and medium speeds in particular. In the paper the authors reveal the results of a DOE (Design of Experiment) study involving several design parameters known to affect rattling occurrence. By running a series of purpose-designed tests the authors investigate not only the contribution of each particular parameter but the interactions between them. The results are presented in the form of pareto charts, main effect plots as well as interaction plots. It is expected the outcome of the analysis will aid in a better comprehension of the phenomena as well the definition of valve configurations to minimize their performance degradation.

ProQuest Historical Newspapers: Leftist Newspapers and Periodicals

2021 ◽  
Vol 23 (2) ◽  
pp. 34-37
Author(s):  
Thomas J. Beck
Keyword(s):  
Twentieth Century ◽  
Price Information ◽  
Social Democrats ◽  
Search Function ◽  
Advanced Search ◽  
Definition Of ◽  
The Cost ◽  
Pdf Format ◽  
Database Content ◽  
Insight Into

ProQuest Historical Newspapers: Leftist Newspapers and Periodicals is a source for leftist publications (mostly newspapers), largely published in the twentieth century. Here, the user can access articles in PDF format from 156 national and international publications. Navigating this database and the documents therein can be easily done, but articles cannot be magnified or reduced, which may prove problematic with PDFs of old newspapers. Database content can be found through browsing or by using a basic and/or advanced search. The browse and basic search options here are understandable, but the advanced search is not self-explanatory and can possibly confuse the user. As a consequence, a new user of this database will probably benefit from instruction in its use from either the vendor or someone else familiar with this resource. However, when this search function is used properly it can produce numerous, on-point results for any query. The same is true of the basic search and browsing features, though they tend to produce larger lists of results that are less on-point than the advanced search. The vendor did not provide specific price information for this review, only indicating that pricing is determined by an institution's size and number of users. As this provides potential subscribers with very little insight into the cost of acquiring this resource, its advised that they contact ProQuest for a price quote tailored to their own institution. Its licensing agreement is the same as those used for all ProQuest databases and is average in its composition (though somewhat longer than average). The quality and quantity of content in this resource is notable, and it will certainly be of use to those looking for articles from leftist newspapers and periodicals. However, the definition of “leftist” here may be problematic for some users! Communist and Socialist publications are certainly available in this database, but those for Anarchists, Social Democrats, and other leftists are not.

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