Response of breeding sows to long term dietary supplementation with folic acid

Author(s):  
P.B. Lynch ◽  
P.J.A. Sheehy

Dietary supplementation with folic acid has been shown to improve reproductive performance in sows (Lindemann 1993). However most studies have been for one cycle only and few have examined the effect of supplementation over several parities.One hundred and thirty four crossbred sows ranging in parity from 2 to 4 were selected at farrowing and randomly allocated to two dietary treatments of low and high supplemental folic acid (0 and 10 g per tonne, Roche Products Ltd.). Treatments were applied for the following three lactations and post weaning periods, two full pregnancies and to day 30 of the pregnancy following the third lactation. The diet fed contained barley, wheat, soyabean meal and meat and bone meal with nutrient levels of 14.0 MJ DE/kg and 1.02% lysine. Sows were individually penned throughout with restricted feeding in pregnancy (2.2 kg/day increasing to 2.5 kg/day in the final month), and ad libitum in lactation (approx 5.0 kg/day) and post weaning (approx 3.4 kg/day). Blood samples for determination of plasma and red cell folate were taken from 14 sows per treatment on days 4, 50 and 110 of one cycle. These were determined by a microbiological assay (modification of methods of Scott et al 1974 and Wilson and Home 1982).


1970 ◽  
Vol 10 (46) ◽  
pp. 526
Author(s):  
ES Batterham

Experiments were conducted to determine the effect of rate of feeding on the differences in growth promoting ability of wheat-based diets containing meat meal or meat and bone meal as the sole protein supplement for pigs. The value of laboratory rats in assessing diet quality for pigs was also investigated. There was no difference in the growth promoting abilities of diets containing MM or MBM under restricted feeding but under ad lib. feeding variation between the diets occurred. Rat responses to the dietary treatments were inconsistent with the pig responses. The results confirmed previous findings that under restricted feeding meat meals and meat and bone meals had similar growth promoting abilities for pigs.



Nutrients ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 1957
Author(s):  
Alessandra Vezzoli ◽  
Cinzia Dellanoce ◽  
Teresa Maria Caimi ◽  
Daniele Vietti ◽  
Michela Montorsi ◽  
...  

Hyperhomocysteinemia is recognized as risk factor for cardiovascular and age-associated diseases. Folic acid supplementation efficiently lowers plasma homocysteine (Hcy) levels, but high intake may negatively affect health because of unnatural levels of unmetabolized folic acid in the systemic circulation. Oxoproline (Oxo) provides by glutamic acid production an increase of intracellular folic acid trapping. Aim of this study was to compare the efficacy of three supplementation protocols: (1) traditional therapy (5-methyl-tetrahydrofolate: 15 mg/day); (2) 5 mL/day of Oxo with 300 μg folic acid (oxifolic); (3) 5 mL/day of Oxo alone (magnesio+) in a 90 days randomized trial on thirty-two moderate hyperhomocysteinemic (18.6 ± 2.4 μmol·L−1) patients (age 48 ± 14 years). Thiols: cysteine (Cys), cysteinylglycine (Cys–Gly) and glutathione levels were assessed too. Every supplementation induced significant (p range <0.05–0.0001) reductions of Hcy level and Cys concentration after the three protocols adopted. Otherwise glutathione concentration significantly increased after oxifolic (p < 0.01) and traditional (p < 0.05) supplementation. The integration of Oxo resulted an interesting alternative to traditional therapy because absence or minimal number of folates in the integrator eliminates any chance of excess that can constitute a long-term risk.



Medicina ◽  
2019 ◽  
Vol 55 (7) ◽  
pp. 337 ◽  
Author(s):  
Rondanelli ◽  
Faliva ◽  
Gasparri ◽  
Peroni ◽  
Naso ◽  
...  

Background and objective: Often micronutrient deficiencies cannot be detected when patient is already following a long-term gluten-free diet with good compliance (LTGFDWGC). The aim of this narrative review is to evaluate the most recent literature that considers blood micronutrient deficiencies in LTGFDWGC subjects, in order to prepare dietary supplementation advice (DSA). Materials and methods: A research strategy was planned on PubMed by defining the following keywords: celiac disease, vitamin B12, iron, folic acid, and vitamin D. Results: This review included 73 studies. The few studies on micronutrient circulating levels in long-term gluten-free diet (LTGFD) patients over 2 years with good compliance demonstrated that deficiency was detected in up to: 30% of subjects for vitamin B12 (DSA: 1000 mcg/day until level is normal, then 500 mcg), 40% for iron (325 mg/day), 20% for folic acid (1 mg/day for 3 months, followed by 400–800 mcg/day), 25% for vitamin D (1000 UI/day or more-based serum level or 50,000 UI/week if level is <20 ng/mL), 40% for zinc (25–40 mg/day), 3.6% of children for calcium (1000–1500 mg/day), 20% for magnesium (200–300 mg/day); no data is available in adults for magnesium. Conclusions: If integration with diet is not enough, starting with supplements may be the correct way, after evaluating the initial blood level to determine the right dosage of supplementation.



The Analyst ◽  
1998 ◽  
Vol 123 (12) ◽  
pp. 2513-2516 ◽  
Author(s):  
Dick Hooijerink ◽  
Robert Schilt ◽  
Bert Brouwer ◽  
Eric van Bennekom


2014 ◽  
Vol 32 (5) ◽  
pp. 423-433 ◽  
Author(s):  
Małgorzata Wzorek

The objective of this article is to elaborate a method to optimize the composition of the fuels from sewage sludge (PBS fuel – fuel based on sewage sludge and coal slime, PBM fuel – fuel based on sewage sludge and meat and bone meal, PBT fuel – fuel based on sewage sludge and sawdust). As a tool for an optimization procedure, the use of a genetic algorithm is proposed. The optimization task involves the maximization of mass fraction of sewage sludge in a fuel developed on the basis of quality-based criteria for the use as an alternative fuel used by the cement industry. The selection criteria of fuels composition concerned such parameters as: calorific value, content of chlorine, sulphur and heavy metals. Mathematical descriptions of fuel compositions and general forms of the genetic algorithm, as well as the obtained optimization results are presented. The results of this study indicate that the proposed genetic algorithm offers an optimization tool, which could be useful in the determination of the composition of fuels that are produced from waste.



2011 ◽  
Vol 59 (17) ◽  
pp. 9475-9483 ◽  
Author(s):  
Nicole Tanz ◽  
Roland A. Werner ◽  
Wolfgang Eisenreich ◽  
Hanns-Ludwig Schmidt


2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 62-62
Author(s):  
Patrick von Schaumburg ◽  
Fei He ◽  
Heather Mangian ◽  
Jolene Hoke ◽  
Maria R C de Godoy

Abstract The human interest of ancient grains replacing modern carbohydrate sources has reached the pet food market, and there has been increased focus on corn- and wheat-free diets in pet foods. The objectives of this research were to evaluate the effect of dietary supplementation of white and red sorghum grains on the gastrointestinal health of felines through the determination of apparent total tract macronutrient digestibility (ATTD), fecal characteristics, fermentative end-products, microbiota, and how the sorghum grains compared against a traditionally corn-based diet. Three diets containing 30% corn (CO), 30% white sorghum (WS), or 30% red sorghum (RS) were formulated to meet or exceed the AAFCO (2017) nutritional requirements for felines. Nine male cats were randomly assigned to one of the 3 dietary treatments using a replicated 3x3 Latin square design. Experiment periods consisted of 14 days (10 days of diet adaption + 4 days of total, fresh collection). All diets were highly digested by cats, however, ATTD of dry matter was highest (P &lt; 0.05) for RS (81.13%) and lowest for CO (78.28%), organic matter was greatest (P &lt; 0.05) for RS (86.40%) and lowest for CO (84.15%), crude protein was similar amongst diets with a range of 84.52%-86.57%, acid hydrolyzed fat was similar amongst diets with a range of 91.36%–92.79%, and total dietary fiber was greatest (P &lt; 0.05) in WS (55.96%) with CO being lowest (44.66%). Fecal pH (6.28–6.54) and most metabolites did not differ among diets (P &gt; 0.05), except for phenol/indole concentrations that were significantly lower (P &lt; 0.05) in cats fed RS (178.88 ug/g) compared to CO (240.34 ug/g). Overall, the data gathered suggest that dietary supplementation of WS and RS as carbohydrate sources were well tolerated by the cats. Thus, sorghum is an acceptable alternative to corn in extruded diets of felines.



1976 ◽  
Vol 16 (80) ◽  
pp. 372 ◽  
Author(s):  
AT Goold ◽  
MR Taverner ◽  
RW Hodge

Twenty-five pigs, weaned at approximately three weeks of age, were randomly allocated to five dietary treatments containing increasing levels of low glucosinolate rapeseed meal (0, 1.5, 3.0, 6.0, 9.0 per cent) substituted for equal amounts of protein from meat and bone meal. The diets were offered ad libitum and the pigs' performance and digestibility were recorded from approximately 5 to 21 kg liveweight. The level of rapeseed meal in the diet did not significantly affect either the voluntary feed intake, food conversion ratio, growth rate or dry matter digestibility. However, food wastage significantly increased as the level of rapeseed meal in the diet was increased from 1.5 to 9.0 per cent. Food wastage was significantly correlated with the level of rapeseed meal in the diet.



1958 ◽  
Vol 41 (2) ◽  
pp. 411-413
Author(s):  
Milton Lapidus ◽  
Edward F Mellon
Keyword(s):  


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