scholarly journals Sensing Methodology for the Rapid Monitoring of Biomolecules at Low Concentrations over Long Time Spans

ACS Sensors ◽  
2021 ◽  
Author(s):  
Rafiq M. Lubken ◽  
Max H. Bergkamp ◽  
Arthur M. de Jong ◽  
Menno W. J. Prins
2003 ◽  
Vol 27 (3) ◽  
pp. 213-217 ◽  
Author(s):  
Betul Kargul ◽  
Esber Caglar ◽  
Ilknur Tanboga

Fluoride, the milestone element of pediatric dentistry, as well as modern dentistry, has been utilized for the last six decades in practice. Researchers all over the world have used fluoride in several forms in the prevention of tooth decay.Today, we are aware that most of this work has involved clinical research with children. It is particularly pertinent that the subject be adequately presented in the field of pediatric dentistry. In 1940's and 1950's were the years of ten-year studies, where caries reductions were first described. The industry of systemic fluoridation, public campaigns and advertisements became popular mostly in western world in 1960's and 1970's. The fluoridated dentifrices and changes of dentrifice formulations were established in 1980's. Many stated that children should receive one form of systemic fluoride and appropriate forms of topical fluoride in 1990's. Analyses showed that maximum protection against caries is obtained when teeth erupt into an environment with low concentrations of ionic fluoride. The similarity in caries reductions obtained in water fluoridation studies and long-term studies with topically administered fluoride regimens, including fluoride-containing dentifrices, indicates that the pre-eruptive effect of fluoride is of borderline significance relative to the more significant post-eruptive effect. It has taken a long time to show that water fluoridation and topical fluoride programs were thus important measures for the control of caries at the community level. Today, we are aware of the fact that the trio of diet, dentifrice and supplementation should exceed the optimal levels.


2017 ◽  
Vol 2 (1) ◽  
pp. 15 ◽  
Author(s):  
Suratno Suratno ◽  
Muhammad Reza Cordova ◽  
Silke Arinda

<strong>Mercury Content in Commercial Fishes of Bantul Areas and Yogyakarta. </strong> Mercury Content in Commercial Fishes of Bantul Areas and Yogyakarta Fish is an important energy source for the body and has many functions for human health. Hence, the fish are highly favored for consumption by the public. However, the fish has the ability to accumulate heavy metals. One type of dangerous heavy metals and can accumulate in fish is mercury because it has high toxicity at low concentrations. The presence of contaminants from anthropogenic activities that are not processed previously, makes the fish a potential hoarder for heavy metals. This study examined the concentration of mercury in freshwater fish and saltwater fish consumed by the people of Bantul areas and Yogyakarta. Fish samples were collected on 29–30 August 2015 from Prawirotaman Market, supermarket, Embankment on the River Code, and purchased from fishermen in Depok Beach. Analysis of mercury concentrations in fish was done using mercury analyzer NIC MA-3000. The results indicated that the fish with the eating habits of benthivore and planktivore accumulated higher mercury than omninore and carnivore fish. The concentration of mercury in the fish examined does not exceed the threshold of the WHO standard, BPOM-RI, and European Union standards. However, the people need to be alert on mercury bioaccumulative properties, especially when consuming the fish having accumulated mercury continuously for a long time.


2020 ◽  
Vol 213 ◽  
pp. 01032
Author(s):  
Zhaohong Meng ◽  
Shuman Wang ◽  
Jia Zhou

Soil microbial environment have been affected by different concentration heavy metals Cd (HM) and tylosin (TYL) and combination of TYL and HM interactions. Degradation of TYL was caused certain inhibition due to the addition of HM. The germination index of seed had been inhibited owing to the toxic effects of HM and TYL, but we found that the low concentrations of HM (4 mg/kg), the germination index higher than the soil which unadded HM and TYL in it. The soil enzyme activity was significantly suppressed by the addition of HM and TYL. Actinomycete was inhibited by high concentrations of HM for a long time. The studies demonstrated that the pollution of the soil micro-environment has been serious than only add HM or TYL in the soil.


2010 ◽  
Vol 64 (1-2) ◽  
pp. 83-92
Author(s):  
Radmila Markovic ◽  
Dragan Sefer ◽  
Stamen Radulovic ◽  
Marcela Speranda

Mycotoxins present a significant problem in the diet of pigs. Secondary metabolites of fungi are toxic matter that have a negative effect on health and the performance of animals, as well as on the quality of their products. The creating of mycotosins is a complex process and it is difficult to predict which toxin will be produced and in which concentration. Food is most often contaminated by low concentrations of different mycotoxins (aflatoxins, ochratoxins, trichothecenes, fumonisinsi and zearalenone) which cause a series of undesired effects, depending on the amount that the animal has ingested into the organism. Mycotoxin interactions in the organism are complex, and they can have antagonistic, synergistic or a joint effect, depending on the combination and quantity in which they appear. The pig is a domestic animal which is most sensitive to the effects of mycotoxins. Long-term consumption of feed contaminated with mycotoxins results in a decline in production, a deterioration of the general health and reproductive disorders. One of the most important negative effects in pigs which receive low doses of mycotoxins in the longterm, is immunosuppression. Mycotoxins present very stable links that remain in raw materials and animal products for a long time and thus pose a major health risk for humans. .


2021 ◽  
Vol 284 ◽  
pp. 01009
Author(s):  
Elena Popova

The paper presents the results of comprehensive studies on the problem of formation of a deposit of heavy metals in plant communities of the West Siberian Arctic and Subarctic. The regularities of the concentration and redistribution of heavy metals in the soil-plant system have been revealed. Excessive accumulation of heavy metals by different plant species is limited by the selectivity of root absorption in relation to certain elements, and therefore it is important to calculate the coefficient of biological absorption. The interrelation between the intensity of recreational loading and change in the nature, grass cover structure.Among the identified pollutants that accumulate by plants identified a group of heavy metals and microelements (Pb, Sr, Cu, Zn, Ni ). It is shown that the linear dependence of the accumulation of metals in the system “soil-plant” is observed only in the range of low concentrations of pollutants in the ground growing. With high concentrations the reverse dependence occurs. Formulated, justified and tested methodical approaches to preparation of complex long-time observations of the natural ecosystems.


1999 ◽  
Vol 32 (11) ◽  
pp. 3809-3816 ◽  
Author(s):  
Jan K. G. Dhont ◽  
Michel P. B. van Bruggen ◽  
W. J. Briels

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0256905
Author(s):  
Tahereh Mirakhorli ◽  
Zahra Oraghi Ardebili ◽  
Alireza Ladan-Moghadam ◽  
Elham Danaee

Nanoscience paves the way for producing highly potent fertilizers and pesticides to meet farmer’s expectations. This study investigated the physiological and molecular responses of soybean seedlings to the long-time application of zinc oxide nanoparticles (ZnO NPs) and their bulk type (BZnO) at 5 mg L-1 under the two application methods (I- foliar application; II- soil method). The ZnO NPs/BZnO treatments in a substance type- and method-dependent manner improved plant growth performance and yield. ZnO NPs transactionally upregulated the EREB gene. However, the expression of the bHLH gene displayed a contrary downward trend in response to the supplements. ZnO NPs moderately stimulated the transcription of R2R3MYB. The HSF-34 gene was also exhibited a similar upward trend in response to the nano-supplements. Moreover, the ZnONP treatments mediated significant upregulation in the WRKY1 transcription factor. Furthermore, the MAPK1 gene displayed a similar upregulation trend in response to the supplements. The foliar application of ZnONP slightly upregulated transcription of the HDA3 gene, while this gene showed a contrary slight downregulation trend in response to the supplementation of nutrient solution. The upregulation in the CAT gene also resulted from the nano-supplements. The concentrations of photosynthetic pigments exhibited an increasing trend in the ZnONP-treated seedlings. The applied treatments contributed to the upregulation in the activity of nitrate reductase and the increase in the proline concentrations. ZnO NPs induced the activity of antioxidant enzymes, including peroxidase and catalase by averages of 48.3% and 41%, respectively. The utilization of ZnO NPs mediated stimulation in the activity of phenylalanine ammonia-lyase and increase in soluble phenols. The findings further underline this view that the long-time application of ZnO NPs at low concentrations is a safe low-risk approach to meet agricultural requirements.


2021 ◽  
Vol 11 (16) ◽  
pp. 7697
Author(s):  
Zdeňka Panovská ◽  
Vojtech Ilko ◽  
Marek Doležal

Scientific literature on indoor air quality is categorised mainly into environmental sciences, construction building technology and environmental and civil engineering. Indoor air is a complex and dynamic mixture of a variety of volatile and particulate matter. Some of the constituents are odorous and originate from various sources, such as construction materials, furniture, cleaning products, goods in stores, humans and many more. The first part of the article summarises the knowledge about the substances that are found in the air inside buildings, especially stores, and have a negative impact on our health. This issue has been monitored for a long time, and so, using a better methodology, it is possible to identify even low concentrations of monitored substances. The second part summarises the possibility of using various aromatic substances to improve people’s sense of the air in stores. In recent times, air modification has come to the forefront of researchers’ interest in order to create a more pleasant environment and possibly increase sales.


2013 ◽  
Vol 8 (11) ◽  
pp. 1112-1118
Author(s):  
Iliana Velcheva ◽  
Elenka Georgieva ◽  
Pepa Atanassova

AbstractWe investigated the influence of copper in a long-time treatment with concentrations of 0.05 mg L−1 and 0.1 mg L−1 to track the histopathological changes in gills of Carassius gibelio, and to find at what extent they will recover after the effect of the copper concentrations stops. Treatment with copper lasted 21 days and the recovery time was of the same duration. The results of histological examination showed degenerative changes (resulting in thinner secondary lamellae and filamentary epithelium), and hyperplastic and hypertrophic changes (proliferation, vasodilatation, aneurysms, epithelial interstitial edema, and fusion) in gills under the influence of two concentrations. The degenerative changes have higher prevalence at low concentrations, while hyperplastic and hypertrophic ones — at high concentrations. After the period of recovery they remained the same, but the extent of expression on the surface of gill filaments changed. The long-time copper intoxication in low concentrations of copper affects gill structure, causing severe changes whose recovery is a slow process that requires a longer period of time.


2010 ◽  
Vol 1 (2) ◽  
pp. 31-37
Author(s):  
V. I. Karpenko ◽  
L. P. Golodok ◽  
M. V. Vodka ◽  
A. A. Dyachenko ◽  
L. A. Sirenko

The methods and a laboratory bench have been developed for research of the multienzyme systems of cyanobacteriae Mycrocystis aeruginosa. The bench allows regulating the luminous intensity and suspension agitation, studying the cells reproduction and conducting the chemical analysis of water. It has been established that algae can be used in a biofilter for reducing low concentrations of total iron in water to the levels which meet state standard (GOST 2874-82) requirements. Algae cells reproduction during water treatment from iron in a biofilter indicates that the number of enzyme systems and their activity increase. The advantage of the algae multienzyme systems use for the water treatment is the fact that they maintain their activity for a long time and do not need any carbonaceous energy substrata.


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