scholarly journals High-Resolution Ion-Mobility-Enabled Peptide Mapping for High-Throughput Critical Quality Attribute Monitoring

2021 ◽  
Author(s):  
James R. Arndt ◽  
Kelly L. Wormwood Moser ◽  
Gregory Van Aken ◽  
Rory M. Doyle ◽  
Tatjana Talamantes ◽  
...  
Keyword(s):  
High Resolution ◽  
High Throughput ◽  
Ion Mobility ◽  
Peptide Mapping ◽  
Quality Attribute ◽  
Critical Quality Attribute

scholarly journals Applications of ion mobility mass spectrometry for high throughput, high resolution glycan analysis

2016 ◽  
Vol 1860 (8) ◽  
pp. 1688-1709 ◽  
Author(s):  
C.J. Gray ◽  
B. Thomas ◽  
R. Upton ◽  
L.G. Migas ◽  
C.E. Eyers ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
High Throughput ◽  
Ion Mobility ◽  
Ion Mobility Mass Spectrometry ◽  
Glycan Analysis

scholarly journals Rapid cyclic ion mobility separations of monosaccharide building blocks as a first step toward a high-throughput reaction screening platform for carbohydrate syntheses

RSC Advances ◽  
2021 ◽  
Vol 11 (63) ◽  
pp. 39742-39747
Author(s):  
Tyler L. Peterson ◽  
Gabe Nagy
Keyword(s):  
High Resolution ◽  
High Throughput ◽  
Ion Mobility ◽  
Building Blocks ◽  
Rapid Resolution ◽  
Screening Platform

High-resolution cyclic ion mobility separations enable the rapid resolution of α/β anomers in carbohydrate building blocks and their associated anomeric impurities.

Trapped ion mobility spectrometry time-of-flight mass spectrometry for high throughput and high resolution characterization of human milk oligosaccharide isomers

2021 ◽  
pp. 338878
Author(s):  
Aurélie Delvaux ◽  
Estelle Rathahao-Paris ◽  
Blanche Guillon ◽  
Sophie Cholet ◽  
Karine Adel-Patient ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
High Throughput ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Trapped Ion ◽  
Flight Mass Spectrometry ◽  
Trapped Ion Mobility Spectrometry ◽  
Human Milk Oligosaccharide

scholarly journals The potential of Ion Mobility Mass Spectrometry for high-throughput and high-resolution lipidomics

2018 ◽  
Vol 42 ◽  
pp. 42-50 ◽  
Author(s):  
Christine Hinz ◽  
Sonia Liggi ◽  
Julian L Griffin
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
High Throughput ◽  
Ion Mobility ◽  
Ion Mobility Mass Spectrometry

Cross Section Analysis of Cu Filled TSVs Based on High Throughput Plasma-FIB Milling

2012 ◽  
Author(s):  
Frank Altmann ◽  
Jens Beyersdorfer ◽  
Jan Schischka ◽  
Michael Krause ◽  
German Franz ◽  
...  
Keyword(s):  
High Resolution ◽  
Cross Section ◽  
High Throughput ◽  
Cross Sections ◽  
Electron Backscatter Diffraction ◽  
Grain Structure ◽  
Electron Backscatter ◽  
Section Surface ◽  
Backscatter Diffraction ◽  
Section Analysis

Abstract In this paper the new Vion™ Plasma-FIB system, developed by FEI, is evaluated for cross sectioning of Cu filled Through Silicon Via (TSV) interconnects. The aim of the study presented in this paper is to evaluate and optimise different Plasma-FIB (P-FIB) milling strategies in terms of performance and cross section surface quality. The sufficient preservation of microstructures within cross sections is crucial for subsequent Electron Backscatter Diffraction (EBSD) grain structure analyses and a high resolution interface characterisation by TEM.

scholarly journals Micromechanical Punching: A Versatile Method for Non-Spherical Microparticle Fabrication

Polymers ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 83
Author(s):  
Ritika Singh Petersen ◽  
Anja Boisen ◽  
Stephan Sylvest Keller
Keyword(s):  
Drug Delivery ◽  
High Resolution ◽  
Physicochemical Properties ◽  
High Throughput ◽  
Liquid State ◽  
Soft Lithography ◽  
Glycolic Acid ◽  
Thermosetting Polymers ◽  
Spherical Microparticle ◽  
Spherical Microparticles

Microparticles are ubiquitous in applications ranging from electronics and drug delivery to cosmetics and food. Conventionally, non-spherical microparticles in various materials with specific shapes, sizes, and physicochemical properties have been fabricated using cleanroom-free lithography techniques such as soft lithography and its high-resolution version particle replication in non-wetting template (PRINT). These methods process the particle material in its liquid/semi-liquid state by deformable molds, limiting the materials from which the particles and the molds can be fabricated. In this study, the microparticle material is exploited as a sheet placed on a deformable substrate, punched by a robust mold. Drawing inspiration from the macro-manufacturing technique of punching metallic sheets, Micromechanical Punching (MMP) is a high-throughput technique for fabrication of non-spherical microparticles. MMP allows production of microparticles from prepatterned, porous, and fibrous films, constituting thermoplastics and thermosetting polymers. As an illustration of application of MMP in drug delivery, flat, microdisk-shaped Furosemide embedded poly(lactic-co-glycolic acid) microparticles are fabricated and Furosemide release is observed. Thus, it is shown in the paper that Micromechanical punching has potential to make micro/nanofabrication more accessible to the research and industrial communities active in applications that require engineered particles.

scholarly journals Development of High-Throughput, High-Resolution 3D Reconstruction of Large-Volume Biological Tissue Using Automated Tape Collection Ultramicrotomy and Scanning Electron Microscopy

2011 ◽  
Vol 17 (S2) ◽  
pp. 966-967 ◽  
Author(s):  
R Schalek ◽  
N Kasthuri ◽  
K Hayworth ◽  
D Berger ◽  
J Tapia ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
High Resolution ◽  
3D Reconstruction ◽  
High Throughput ◽  
Large Volume ◽  
Biological Tissue ◽  
Scanning Electron

Extended abstract of a paper presented at Microscopy and Microanalysis 2011 in Nashville, Tennessee, USA, August 7–August 11, 2011.

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