Efficacy and Safety of Regular Vitamin and Mineral Supplement Use in France: Results from the ECCA Study

2005 ◽  
Vol 75 (3) ◽  
pp. 201-209 ◽  
Author(s):  
Touvier ◽  
Boutron-Ruault ◽  
Volatier ◽  
Martin

This study investigated the prevalence of inadequate micronutrient intake and the proportion of subjects who exceed Tolerable Upper Intake Levels a) with food only, and b) with food+supplements, in a population of French regular supplement users (n = 259). Assessment tools were seven-day records for supplements, three-day records for food intake, and a questionnaire about supplement use. Most subjects were recruited in retail outlets that sold supplements. They were recent users of vitamin/mineral supplements, aged over 15 years, and normo-energy reporters. The prevalence (%) of inadequate intake decreased with the inclusion of mean annual supplements, from 68.0 to 54.8 for magnesium, 55.9 to 40.7 for vitamin C, 53.4 to 43.9 for folic acid, 37.5 to 27.5 for iron, and 40.1 to 29.7 for pantothenic acid. Few subjects exceeded upper intake levels when mean annual intake of supplements was considered. When supplement consumption was considered during the studied week only, the proportion of subjects who were in excess of the upper intake levels was higher (maximum: 9.6% for magnesium). Supplement use brought a nutritional benefit for some targeted nutrients. It was not associated with excessive intake in this study, but could become hazardous if the annual frequency of use were to increase.

2019 ◽  
Vol 44 (4) ◽  
pp. 450-453 ◽  
Author(s):  
Katherine L. Ford ◽  
Derek J. Jorgenson ◽  
Eric J.L. Landry ◽  
Susan J. Whiting

Individuals who take medications may benefit from using vitamin and/or mineral supplements (VMS) yet excess supplementation can lead to overuse (daily intake exceeding the tolerable upper intake level (UL)). This study assessed VMS use of medically complex, community-living, older adults. A chart review of 229 patients ≥50 years with new medication assessments between 2014 and 2017 indicated that 76.9% of patients used ≥1 VMS daily. The UL for one or more nutrients was exceeded by 39.8% of supplement users.


2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 812-812
Author(s):  
Katherine Sauder ◽  
Robyn Harte ◽  
Brandy Ringham ◽  
Patricia Guenther ◽  
Regan Bailey ◽  
...  

Abstract Objectives Both inadequate and excessive intake of micronutrients in pregnancy have the potential to negatively impact child health outcomes. We examined micronutrient intake in a large, diverse sample of women with singleton pregnancies across the United States, including intake by maternal age, race/ethnicity, education, and pre-pregnancy body mass index (BMI). Methods Fifteen observational cohorts in the Environmental influences on Child Health Outcomes (ECHO) consortium assessed prenatal food intake and dietary supplement use with 24-hour dietary recalls (5 cohorts; 1859 women) or food frequency questionnaires (10 cohorts; 8064 women) from 1999–2019. We compared mean daily intake of 19 micronutrients to the age-specific estimated average requirement (EAR), adequate intake (AI), and tolerable upper intake level (UL) for pregnancy, overall and within sociodemographic and anthropometric subgroups. For recall data, we used a measurement error method to estimate distributions of usual intake, proportion below the EAR/AI, and above the UL. For FFQ data, we calculated the proportion below the EAR/AI and above the UL. Results Risk of inadequate intake from foods alone ranged from 0–93%, depending on the micronutrient or assessment method. With dietary supplements, more than 1 in 5 women remained at risk for inadequate intake of choline, magnesium, and vitamins D, E, and K; or excessive intake of folic acid, iron, and zinc. Higher risks for inadequate intakes were observed among women with obesity (magnesium, vitamin K), who were <18 years (magnesium, vitamin K), Hispanic (vitamin E), non-Hispanic Black (vitamin K), non-Hispanic White (choline) or less educated (magnesium, vitamin E) when compared to counterparts. Conclusions Improved diet quality is needed for most pregnant women. Even with a high prevalence of dietary supplement use, at least 1 in 5 pregnant women were at risk of inadequate intake of ≥ 1 micronutrients, especially in some population subgroups. Pregnancy may be a window of opportunity to address disparities in micronutrient intake that could contribute to intergenerational health inequalities. Funding Sources National Institutes of Health, Environmental Protection Agency, Autism Speaks.


2005 ◽  
Vol 39 (6) ◽  
pp. 1019-1023 ◽  
Author(s):  
Mukaila A Raji ◽  
Yong-Fang Kuo ◽  
Soham Al Snih ◽  
Belal M Sharaf ◽  
Jose A Loera

BACKGROUND: Little information exists on herb and vitamin—mineral supplement use in very old people and whether use varies by ethnicity. OBJECTIVE: To examine the prevalence and predictors of herb and vitamin—mineral supplement use in a triethnic sample of adults aged ⩾77 years. METHODS: In-home interviews in 1997–1998 assessed medications use and sociodemographic and health factors in community-dwelling elderly non-Hispanic white (n = 125), black (n = 112), and Hispanic (n = 128) adults. RESULTS: Of the 365 subjects (71.5% ⩾80 y old, 52.6% female), 172 reported using at least one of the preparations (vitamin—mineral supplements 132, herbs alone 21, both herbs and vitamin—mineral supplements 19). Herbal use varied by ethnicity: 12.8% in non-Hispanic whites, 16.1% in blacks, and 4.7% in Hispanics. The most commonly used herbs were garlic, Ginkgo biloba, saw palmetto, and vinegar. Use of vitamin—mineral supplements, alone or combined with herbs, also varied by ethnicity: 54.4% in non-Hispanic whites, 31.3% in blacks, and 37.5% in Hispanics. In the fully adjusted multivariate model with white ethnicity as reference, the odds ratio of vitamin—mineral supplements use for blacks was 0.37 (95% CI 0.21 to 0.65) and for Hispanics was 0.56 (95% CI 0.30 to 1.03). In bivariate analyses, female gender, black ethnicity, being born in the US, and having coronary artery disease were significantly associated with herbal use (p < 0.05); however, in the fully adjusted multivariate model, only the female gender remained significantly associated with herbal use (OR 2.14; 95% CI 1.00 to 4.59). CONCLUSIONS: Use of herbs or vitamin—mineral supplements is common in very old people and varies by ethnicity.


1994 ◽  
Vol 4 (4) ◽  
pp. 320-334 ◽  
Author(s):  
Jeffery Sobal ◽  
Leonard F. Marquart

Vitamin/mineral supplements are often used by athletes as ergogenic aids to improve performance. This paper reviews studies of the prevalence, patterns, and explanations for vitamin/mineral supplement use among athletes. Fifty-one studies provided quantitative prevalence data on 10,274 male and female athletes at several levels of athletic participation in over 15 sports. The overall mean prevalence of athletes’ supplement use was 46%. Most studies reported that over half of the athletes used supplements (range 6% to 100%), and the larger investigations found lower prevalence levels. Elite athletes used supplements more than college or high school athletes. Women used supplements more often than men. Varying patterns existed by sport. Athletes appear to use supplements more than the general population, and some take high doses that may lead to nutritional problems. Sport nutritionists should include a vitamin/mineral supplement history as part of their dietary assessment so they can educate athletes about vitamin/mineral supplements and athletic performance.


2010 ◽  
Vol 71 (2) ◽  
pp. 70-76 ◽  
Author(s):  
Susan J. Whiting ◽  
Hassanali Vatanparast ◽  
Jeff G. Taylor ◽  
Jennifer L. Adolphe

Purpose: We investigated barriers to healthful eating and vitamin/mineral supplement use among groups at risk for low nutrient intakes, particularly those with low income. Methods: Twelve focus groups (73 participants) and 11 key informant interviews were conducted in Saskatoon, Saskatchewan. Focus group participants represented a diverse population. Key informants included health professionals and personnel from community-based organizations who worked in a lowincome area. Focus group meetings and key informant interviews were audiotaped and transcribed; thematic coding was used to identify key concepts. Results: The focus groups and interviews revealed five themes on barriers to healthful eating and to the use of vitamin/mineral supplements: knowledge, income, accessibility, health, and preferences. Key informants were aware of the barriers, and were able to see not only individual and family reasons but also societal influences. Conclusions: The study results provide valuable information for focusing efforts on reducing barriers to healthful eating and to appropriate vitamin/mineral supplement use.


2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Kazue Ishitsuka ◽  
Satoshi Sasaki ◽  
Hidetoshi Mezawa ◽  
Mizuho Konishi ◽  
Maki Igarashi ◽  
...  

Abstract Background A variety of dietary supplements are commercially available. However, the efficacy and safety of dietary supplement use in children are not well established. Understanding dietary supplement use is important for developing public health policy regarding dietary supplements. This study aimed to investigate the types of dietary supplements used and characteristics of dietary supplement users among Japanese elementary school children. Method We conducted a cross-sectional web-based questionnaire study. Dietary supplement use, socio-demographics, and health-related behaviors were assessed through mother-reported questionnaire. Types of dietary supplements were identified based on ingredient using product barcodes and brand names. Multivariate logistic regression analysis was conducted to investigate the socio-demographics and health-related behaviors associated with supplement use. Results Among 4933 children, 333 (6.8%) were identified as dietary supplement users. The most common supplement was amino acids or protein (1.4%), followed by n–3 fatty acids or fish oil (1.0%), probiotics (1.0%), multivitamins (0.9%), multivitamin-minerals (0.8%), and botanicals (0.8%). Overall, any dietary supplement use was significantly associated with the highest frequency of sports participation (odds ratio [OR], 2.58; 95% confidence interval [CI], 1.65–4.02), highest household income (OR, 1.87; 95% CI, 1.13–3.10), highest maternal educational level (OR, 1.82; 95% CI, 1.31–2.52), and male sex (OR, 1.38; 95% CI, 1.09–1.75). The highest frequency of sports participation was significantly associated with higher odds of use of amino acids or protein (OR, 6.06; 95% CI, 1.78–20.6) and multivitamins (OR, 3.56; 95% CI, 1.11–11.5), compared to the lowest frequency of sports participation. Conclusion This study showed that Japanese children primarily use non-vitamin, non-mineral supplements. Non-vitamin, non-mineral supplements should thus be included in future studies aimed at monitoring dietary supplement use. We also found that dietary supplement use in children was associated with sports participation. Guidelines for dietary supplement use for children, in particular sport participants, are needed.


2021 ◽  
pp. 1-15
Author(s):  
Usha Luckock ◽  
Joanna Harnett ◽  
Rose Cairns

ABSTRACT Vitamin and mineral supplements (VMS) are widely available and commonly used. Little is known about patterns of poisoning exposures to VMS in the Australian population. We performed a retrospective study of calls to the New South Wales Poisons Information Centre (NSWPIC), July 2014-June 2019. NSWPIC is Australia’s largest PIC, taking approximately 100,000 calls/year (50% of Australian poisoning calls) from healthcare professionals and members of the public. We conducted additional analyses on iron exposures due to their high risk of acute toxicity. There were 10 944 VMS exposures reported to NSWPIC during the study period, increasing 9.6% per annum over a five year period (95%CI, 7.2 – 12.1%). Toddlers (1-4 years) accounted for 41.5% (4546) of cases. Agents most commonly involved were multivitamins (n=3610), Vitamin D (n=2080), iron (n=1533), and magnesium (n=804). In 17.7% (1934) of cases the call originated from hospital or the patient was referred to hospital by NSWPIC. Iron exposures increased by 14.0% per year (95%CI, 9.5 – 18.5%), and most were associated with high strength products (>45 mg elemental iron per unit dose, n=1036). Iron exposures were hospitalised in 38% of cases (n=583). We conclude that vitamin and mineral supplement exposures are increasing in Australia. Although most exposures can be managed at home, many required hospitalisation. Iron exposures are increasing and had higher rates of hospitalisation than other agents. Vitamin and mineral supplements are often considered safe and without the potential for adverse effects, highlighting the importance of public education into the potential risks of misuse of these products.


2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 77-77
Author(s):  
Iris Ho In Cheang-Deis ◽  
Oluwatobi Oyedeji ◽  
Hushton Block ◽  
Kateryn Rochon ◽  
Mika Asai-Coakwell ◽  
...  

Abstract Garlic products have been reported to have antimicrobial effects and may trigger anemia in horses, but their direct impact on feedlot cattle has not been detailed. With increased free-choice feeding of garlic-infused mineral supplements to beef cattle, it is important to evaluate this strategy’s impact on the animals’ health and the potential impact on carcass qualities. This 2-yr study recruited 208 crossbred feedlot steers in a supplementation trial using a completely randomized design. Each year, 104 steers were assigned to 1 of 4 groups that received either non-garlic mineral supplement (MS), MS + 0.3% garlic-oil-based premix (GOil), MS + 2.5% garlic powder (LGP), MS + 5% garlic powder (HGP). Feed and supplements were provided on an ad-lib basis and were measured for each steer with automatic feeding units. The study evaluated health indicators such as blood parameters and internal parasites. At harvest, carcass characteristics (including the incidence of liver abscesses) were assessed for all steers. The groups consumed between 156 and 208 g/d of the supplement over the two years, with the MS group having a lower overall supplement intake than other groups. The average daily consumption of garlic products in GOil, LGP, and HGP were approximately 0.6g/d, 5.2g/d, and 10.1g/d, respectively. There was no difference in total fecal egg counts (P = 0.45) among the groups. There was no association between the treatment groups and incidences of liver abscess scores (P = 0.10) nor carcass grade outcomes (P = 0.84). Further, there were no differences in hot carcass weight (P = 0.90), rib eye area (P = 0.34) and carcass backfat thickness (P = 0.99). All blood parameters evaluated were within normal ranges for all groups. The results suggest that infusing commercial garlic products into mineral supplements is not associated with undesirable effects on cattle health or carcass characteristics.


1990 ◽  
Vol 90 (3) ◽  
pp. 426-428
Author(s):  
Joyce M. Merkel ◽  
Susan J. Crockett ◽  
Rebecca Mullis

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