scholarly journals Factors Affecting Accuracy and Precision in PET Volume Imaging

1991 ◽  
Vol 11 (1_suppl) ◽  
pp. A38-A44 ◽  
Author(s):  
Joel S. Karp ◽  
Margaret E. Daube-Witherspoon ◽  
Gerd Muehllehner

Volume imaging positron emission tomographic (PET) scanners with no septa and a large axial acceptance angle offer several advantages over multiring PET scanners. A volume imaging scanner combines high sensitivity with fine axial sampling and spatial resolution. The fine axial sampling minimizes the partial volume effect, which affects the measured concentration of an object. Even if the size of an object is large compared to the slice spacing in a multiring scanner, significant variation in the concentration is measured as a function of the axial position of the object. With a volume imaging scanner, it is necessary to use a three-dimensional reconstruction algorithm in order to avoid variations in the axial resolution as a function of the distance from the center of the scanner. In addition, good energy resolution is needed in order to use a high energy threshold to reduce the coincident scattered radiation.

2013 ◽  
Vol 46 (2) ◽  
pp. 512-524 ◽  
Author(s):  
S. F. Li ◽  
R. M. Suter

An adaptive orientation reconstruction algorithm is developed for near-field high-energy X-ray diffraction microscopy. When combined with a spatially adaptive extension the algorithm results in a factor of 10–1000 speed-up over the existing forward modeling reconstruction method while preserving most of the spatial and orientation resolution characteristics. Tests of the reconstruction code based on simulated structures and real data on a complex microstructure are presented. Simulated structures include intra-granular orientation gradients and noisy detector images. It is shown that resolution in both real space and orientation space degrades gracefully as complexity and detector noise increase.


2020 ◽  
Vol 50 (1) ◽  
Author(s):  
Hyunung Yu

Abstract Scanning acoustic microscopy (SAM) or Acoustic Micro Imaging (AMI) is a powerful, non-destructive technique that can detect hidden defects in elastic and biological samples as well as non-transparent hard materials. By monitoring the internal features of a sample in three-dimensional integration, this technique can efficiently find physical defects such as cracks, voids, and delamination with high sensitivity. In recent years, advanced techniques such as ultrasound impedance microscopy, ultrasound speed microscopy, and scanning acoustic gigahertz microscopy have been developed for applications in industries and in the medical field to provide additional information on the internal stress, viscoelastic, and anisotropic, or nonlinear properties. X-ray, magnetic resonance, and infrared techniques are the other competitive and widely used methods. However, they have their own advantages and limitations owing to their inherent properties such as different light sources and sensors. This paper provides an overview of the principle of SAM and presents a few results to demonstrate the applications of modern acoustic imaging technology. A variety of inspection modes, such as vertical, horizontal, and diagonal cross-sections have been presented by employing the focus pathway and image reconstruction algorithm. Images have been reconstructed from the reflected echoes resulting from the change in the acoustic impedance at the interface of the material layers or defects. The results described in this paper indicate that the novel acoustic technology can expand the scope of SAM as a versatile diagnostic tool requiring less time and having a high efficiency.


Author(s):  
N. Osakabe ◽  
J. Endo ◽  
T. Matsuda ◽  
A. Tonomura

Progress in microscopy such as STM and TEM-TED has revealed surface structures in atomic dimension. REM has been used for the observation of surface dynamical process and surface morphology. Recently developed reflection electron holography, which employes REM optics to measure the phase shift of reflected electron, has been proved to be effective for the observation of surface morphology in high vertical resolution ≃ 0.01 Å.The key to the high sensitivity of the method is best shown by comparing the phase shift generation by surface topography with that in transmission mode. Difference in refractive index between vacuum and material Vo/2E≃10-4 owes the phase shift in transmission mode as shownn Fig. 1( a). While geometrical path difference is created in reflection mode( Fig. 1(b) ), which is measured interferometrically using high energy electron beam of wavelength ≃0.01 Å. Together with the phase amplification technique , the vertivcal resolution is expected to be ≤0.01 Å in an ideal case.


2000 ◽  
Vol 15 (15) ◽  
pp. 2269-2288
Author(s):  
SANATAN DIGAL ◽  
RAJARSHI RAY ◽  
SUPRATIM SENGUPTA ◽  
AJIT M. SRIVASTAVA

We demonstrate the possibility of forming a single, large domain of disoriented chiral condensate (DCC) in a heavy-ion collision. In our scenario, rapid initial heating of the parton system provides a driving force for the chiral field, moving it away from the true vacuum and forcing it to go to the opposite point on the vacuum manifold. This converts the entire hot region into a single DCC domain. Subsequent rolling down of the chiral field to its true vacuum will then lead to emission of a large number of (approximately) coherent pions. The requirement of suppression of thermal fluctuations to maintain the (approximate) coherence of such a large DCC domain, favors three-dimensional expansion of the plasma over the longitudinal expansion even at very early stages of evolution. This also constrains the maximum temperature of the system to lie within a window. We roughly estimate this window to be about 200–400 MeV. These results lead us to predict that extremely high energy collisions of very small nuclei (possibly hadrons) are better suited for observing signatures of a large DCC. Another possibility is to focus on peripheral collisions of heavy nuclei.


Author(s):  
GuoLong Zhang

The use of computer technology for three-dimensional (3 D) reconstruction is one of the important development directions of social production. The purpose is to find a new method that can be used in traditional handicraft design, and to explore the application of 3 D reconstruction technology in it. Based on the description and analysis of 3 D reconstruction technology, the 3 D reconstruction algorithm based on Poisson equation is analyzed, and the key steps and problems of the method are clarified. Then, by introducing the shielding design constraint, a 3 D reconstruction algorithm based on shielded Poisson equation is proposed. Finally, the performance of two algorithms is compared by reconstructing the 3 D image of rabbit. The results show that: when the depth value of the algorithm is 11, the surface of the rabbit image obtained by the proposed optimization algorithm is smoother, and the details are more delicate and fluent; under different depth values, with the increase of the depth value, the number of vertices and faces of the two algorithms increase, and the optimal depth values of 3 D reconstruction are more than 8. However, the proposed optimization algorithm has more vertices, and performs better in the reconstruction process; the larger the depth value is, the more time and memory are consumed in 3 D reconstruction, so it is necessary to select the appropriate depth value; the shielding parameters of the algorithm have a great impact on the fineness of the reconstruction model. The larger the parameter is, the higher the fineness is. In a word, the proposed 3 D reconstruction algorithm based on shielded Poisson equation has better practicability and superiority.


2021 ◽  
Author(s):  
Luis David Rosales-Vazquez ◽  
Alejandro Dorazco-González ◽  
Victor Sanchez-Mendieta

Optical sensors with high sensitivity and selectivity, as important analytical tools for chemical and environmental research, can be accomplished by straightforward synthesis of luminescent one-, two- and three-dimensional Zn(II) and...


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Chanho Moon ◽  
Kotaro Yamasaki ◽  
Yoshihiko Nagashima ◽  
Shigeru Inagaki ◽  
Takeshi Ido ◽  
...  

AbstractA tomography system is installed as one of the diagnostics of new age to examine the three-dimensional characteristics of structure and dynamics including fluctuations of a linear magnetized helicon plasma. The system is composed of three sets of tomography components located at different axial positions. Each tomography component can measure the two-dimensional emission profile over the entire cross-section of plasma at different axial positions in a sufficient temporal scale to detect the fluctuations. The four-dimensional measurement including time and space successfully obtains the following three results that have never been found without three-dimensional measurement: (1) in the production phase, the plasma front propagates from the antenna toward the end plate with an ion acoustic velocity. (2) In the steady state, the plasma emission profile is inhomogeneous, and decreases along the axial direction in the presence of the azimuthal asymmetry. Furthermore, (3) in the steady state, the fluctuations should originate from a particular axial position located downward from the helicon antenna.


RSC Advances ◽  
2021 ◽  
Vol 11 (23) ◽  
pp. 13898-13905
Author(s):  
Chuan Cai ◽  
He Gong ◽  
Weiping Li ◽  
Feng Gao ◽  
Qiushi Jiang ◽  
...  

A three-dimensional electrospun carbon nanofiber network was used to measure press strains with high sensitivity.


2021 ◽  
Vol 11 (14) ◽  
pp. 6460
Author(s):  
Fabio Di Martino ◽  
Patrizio Barca ◽  
Eleonora Bortoli ◽  
Alessia Giuliano ◽  
Duccio Volterrani

Quantitative analyses in nuclear medicine are increasingly used, both for diagnostic and therapeutic purposes. The Partial Volume Effect (PVE) is the most important factor of loss of quantification in Nuclear Medicine, especially for evaluation in Region of Interest (ROI) smaller than the Full Width at Half Maximum (FWHM) of the PSF. The aim of this work is to present a new approach for the correction of PVE, using a post-reconstruction process starting from a mathematical expression, which only requires the knowledge of the FWHM of the final PSF of the imaging system used. After the presentation of the theoretical derivation, the experimental evaluation of this method is performed using a PET/CT hybrid system and acquiring the IEC NEMA phantom with six spherical “hot” ROIs (with diameters of 10, 13, 17, 22, 28, and 37 mm) and a homogeneous “colder” background. In order to evaluate the recovery of quantitative data, the effect of statistical noise (different acquisition times), tomographic reconstruction algorithm with and without time-of-flight (TOF) and different signal-to-background activity concentration ratio (3:1 and 10:1) was studied. The application of the corrective method allows recovering the loss of quantification due to PVE for all sizes of spheres acquired, with a final accuracy less than 17%, for lesion dimensions larger than two FWHM and for acquisition times equal to or greater than two minutes.


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