Chromosome-wide distribution of haplotype blocks and the role of recombination hot spots

2003 ◽  
Vol 33 (3) ◽  
pp. 382-387 ◽  
Author(s):  
M.S. Phillips ◽  
R. Lawrence ◽  
R. Sachidanandam ◽  
A.P. Morris ◽  
D.J. Balding ◽  
...  
Keyword(s):  
Hot Spots ◽  
Wide Distribution ◽  
Haplotype Blocks ◽  
Recombination Hot Spots

scholarly journals Insertion Hot Spots of DIRS1 Retrotransposon and Chromosomal Diversifications among the Antarctic Teleosts Nototheniidae

2019 ◽  
Vol 20 (3) ◽  
pp. 701 ◽  
Author(s):  
Juliette Auvinet ◽  
Paula Graça ◽  
Laura Ghigliotti ◽  
Eva Pisano ◽  
Agnès Dettaï ◽  
...  
Keyword(s):  
Hot Spots ◽  
Chromosomal Rearrangements ◽  
Antarctic Fish ◽  
Wide Distribution ◽  
Suitable Model ◽  
Fish Family ◽  
The Antarctic ◽  
Antarctic Teleosts

By their faculty to transpose, transposable elements are known to play a key role in eukaryote genomes, impacting both their structuration and remodeling. Their integration in targeted sites may lead to recombination mechanisms involved in chromosomal rearrangements. The Antarctic fish family Nototheniidae went through several waves of species radiations. It is a suitable model to study transposable element (TE)-mediated mechanisms associated to genome and chromosomal diversifications. After the characterization of Gypsy (GyNoto), Copia (CoNoto), and DIRS1 (YNoto) retrotransposons in the genomes of Nototheniidae (diversity, distribution, conservation), we focused on their chromosome location with an emphasis on the three identified nototheniid radiations (the Trematomus, the plunderfishes, and the icefishes). The strong intrafamily TE conservation and wide distribution across species of the whole family suggest an ancestral acquisition with potential secondary losses in some lineages. GyNoto and CoNoto (including Hydra and GalEa clades) mostly produced interspersed signals along chromosomal arms. On the contrary, insertion hot spots accumulating in localized regions (mainly next to centromeric and pericentromeric regions) highlighted the potential role of YNoto in chromosomal diversifications as facilitator of the fusions which occurred in many nototheniid lineages, but not of the fissions.

Ecological, coenotic and floristic analysis of groups of associations of broadleaved-coniferous forests from central European Russia

2001 ◽  
pp. 38-48 ◽  
Author(s):  
L. B. Zaugolnova ◽  
I. I. Istomina ◽  
E. V. Tikhonova
Keyword(s):  
Wide Distribution ◽  
European Russia ◽  
Coniferous Forests ◽  
Computer Data ◽  
East Europe ◽  
Central European ◽  
Reference Base ◽  
Floristic Analysis ◽  
Regional Factors

Two computer data bases were formed: reference base «Prodromus» including the nomenclature forest syntaxa and experienced geobotanic releves «Forests of European Russia». Ecological, coenotic and floristic analysis of broadleaved-coniferous forests mostly corresponding to association Rhodobryo rosei – Piceetum abietis Korotkov 1986 was conducted with these bases. Releves (305) from South taiga and broadleaved-coniferous subzone were used. The analysis revealed complex syntaxonomy, bo­real-nemoral character and wide distribution ass. Rhodobryo-Piceetum from central European Russia. Ecolo­gical comparison of this association with some no­men­clature types of broadleaved-coniferous communities in East Europe was carried out. Preliminary prodromus for Euro­pean Russian mixed forests is suggested. Role of ecologi­cal, succession and regional factors was shown for dif­ferentiation of syntaxa.

Small grains as recombination hot spots in perovskite solar cells

Matter ◽  
2021 ◽  
Author(s):  
Qingzhi An ◽  
Fabian Paulus ◽  
David Becker-Koch ◽  
Changsoon Cho ◽  
Qing Sun ◽  
...  
Keyword(s):  
Solar Cells ◽  
Hot Spots ◽  
Perovskite Solar Cells ◽  
Small Grains ◽  
Recombination Hot Spots

High resolution localization of recombination hot spots using sperm typing

1994 ◽  
Vol 7 (3) ◽  
pp. 420-424 ◽  
Author(s):  
Rene Hubert ◽  
Marcy MacDonald ◽  
James Gusella ◽  
Norman Arnheim
Keyword(s):  
High Resolution ◽  
Hot Spots ◽  
Recombination Hot Spots ◽  
Sperm Typing

scholarly journals Effects of Temperature on the Meiotic Recombination Landscape of the Yeast Saccharomyces cerevisiae

mBio ◽  
2017 ◽  
Vol 8 (6) ◽  
Author(s):  
Ke Zhang ◽  
Xue-Chang Wu ◽  
Dao-Qiong Zheng ◽  
Thomas D. Petes
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Gene Conversion ◽  
Meiotic Recombination ◽  
Hot Spots ◽  
Genetic Maps ◽  
Dna Breaks ◽  
Low Levels ◽  
C 30 ◽  
Recombination Hot Spots ◽  
In Cells

ABSTRACT Although meiosis in warm-blooded organisms takes place in a narrow temperature range, meiosis in many organisms occurs over a wide variety of temperatures. We analyzed the properties of meiosis in the yeast Saccharomyces cerevisiae in cells sporulated at 14°C, 30°C, or 37°C. Using comparative-genomic-hybridization microarrays, we examined the distribution of Spo11-generated meiosis-specific double-stranded DNA breaks throughout the genome. Although there were between 300 and 400 regions of the genome with high levels of recombination (hot spots) observed at each temperature, only about 20% of these hot spots were found to have occurred independently of the temperature. In S. cerevisiae , regions near the telomeres and centromeres tend to have low levels of meiotic recombination. This tendency was observed in cells sporulated at 14°C and 30°C, but not at 37°C. Thus, the temperature of sporulation in yeast affects some global property of chromosome structure relevant to meiotic recombination. Using single-nucleotide polymorphism (SNP)-specific whole-genome microarrays, we also examined crossovers and their associated gene conversion events as well as gene conversion events that were unassociated with crossovers in all four spores of tetrads obtained by sporulation of diploids at 14°C, 30°C, or 37°C. Although tetrads from cells sporulated at 30°C had slightly (20%) more crossovers than those derived from cells sporulated at the other two temperatures, spore viability was good at all three temperatures. Thus, despite temperature-induced variation in the genetic maps, yeast cells produce viable haploid products at a wide variety of sporulation temperatures. IMPORTANCE In the yeast Saccharomyces cerevisiae , recombination is usually studied in cells that undergo meiosis at 25°C or 30°C. In a genome-wide analysis, we showed that the locations of genomic regions with high and low levels of meiotic recombination (hot spots and cold spots, respectively) differed dramatically in cells sporulated at 14°C, 30°C, and 37°C. Thus, in yeast, and likely in other non-warm-blooded organisms, genetic maps are strongly affected by the environment.

scholarly journals Polymerases Leave Fingerprints: Analysis of the Mutational Spectrum in Escherichia coli rpoB To Assess the Role of Polymerase IV in Spontaneous Mutation

2004 ◽  
Vol 186 (9) ◽  
pp. 2900-2905 ◽  
Author(s):  
Erika Wolff ◽  
Mandy Kim ◽  
Kaibin Hu ◽  
Hanjing Yang ◽  
Jeffrey H. Miller
Keyword(s):  
Escherichia Coli ◽  
Exponential Growth ◽  
Hot Spots ◽  
Liquid Culture ◽  
Spontaneous Mutation ◽  
Mutational Spectrum ◽  
Pol Iv ◽  
Rifampin Resistance ◽  
Plasmid Amplification

ABSTRACT We compared the distribution of mutations in rpoB that lead to rifampin resistance in strains with differing levels of polymerase IV (Pol IV), including strains with deletions of the Pol IV-encoding dinB gene, strains with a chromosomal copy of dinB, strains with the F′128 plasmid, and strains with plasmid amplification of either the dinB operon (dinB-yafNOP) or the dinB gene alone. This analysis identifies several hot spots specific to Pol IV which are virtually absent from the normal spontaneous spectrum, indicating that Pol IV does not contribute significantly to mutations occurring during exponential growth in liquid culture.

scholarly journals Epigenetic mechanisms in sexual differentiation of the brain and behaviour

2016 ◽  
Vol 371 (1688) ◽  
pp. 20150114 ◽  
Author(s):  
Nancy G. Forger
Keyword(s):  
Gene Expression ◽  
Sex Differences ◽  
Sexual Differentiation ◽  
Wide Distribution ◽  
Epigenetic Modifications ◽  
Epigenetic Mechanism ◽  
Epigenetic Mechanisms ◽  
Genome Wide ◽  
The Brain

Circumstantial evidence alone argues that the establishment and maintenance of sex differences in the brain depend on epigenetic modifications of chromatin structure. More direct evidence has recently been obtained from two types of studies: those manipulating a particular epigenetic mechanism, and those examining the genome-wide distribution of specific epigenetic marks. The manipulation of histone acetylation or DNA methylation disrupts the development of several neural sex differences in rodents. Taken together, however, the evidence suggests there is unlikely to be a simple formula for masculine or feminine development of the brain and behaviour; instead, underlying epigenetic mechanisms may vary by brain region or even by dependent variable within a region. Whole-genome studies related to sex differences in the brain have only very recently been reported, but suggest that males and females may use different combinations of epigenetic modifications to control gene expression, even in cases where gene expression does not differ between the sexes. Finally, recent findings are discussed that are likely to direct future studies on the role of epigenetic mechanisms in sexual differentiation of the brain and behaviour.

scholarly journals On the role of dust storms in triggering atmospheric gravity waves observed in the middle atmosphere

2011 ◽  
Vol 29 (9) ◽  
pp. 1647-1654 ◽  
Author(s):  
S. K. Das ◽  
A. Taori ◽  
A. Jayaraman
Keyword(s):  
Gravity Waves ◽  
Dust Storm ◽  
Hot Spots ◽  
Middle Atmosphere ◽  
Thermal Structure ◽  
Dust Storms ◽  
Storm Events ◽  
Atmospheric Perturbations ◽  
Atmospheric Gravity

Abstract. Lower atmospheric perturbations often produce measurable effects in the middle and upper atmosphere. The present study demonstrates the response of the middle atmospheric thermal structure to the significant enhancement of the lower atmospheric heating effect caused by dust storms observed over the Thar Desert, India. Our study from multi-satellite observations of two dust storm events that occurred on 3 and 8 May 2007 suggests that dust storm events produce substantial changes in the lower atmospheric temperatures as hot spots which can become sources for gravity waves observed in the middle atmosphere.

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