scholarly journals Impact of consanguineous marriages and degrees of inbreeding on fertility, child mortality, secondary sex ratio, selection intensity, and genetic load: a cross-sectional study from Northern India

2016 ◽  
Vol 81 (1) ◽  
pp. 18-26 ◽  
Author(s):  
Mohd Fareed ◽  
Mir Kaisar Ahmad ◽  
Malik Azeem Anwar ◽  
Mohammad Afzal
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Mohan Wang ◽  
Xiangyin Liu ◽  
Han Zhang ◽  
Leilei Li ◽  
Ruizhi Liu ◽  
...  

Abstract Background The aim of this study was to determine the secondary sex ratio (SSR) of offspring in assisted reproduction technology (ART) in Jilin Province, China, and to analyse the influencing factors associated with SSR. Methods A cross-sectional study of 3833 babies including singletons and twins born to 2990 couples treated by ART between May 2011 and December 2018 was performed. Results The main outcomes of this study were that the SSR of ART babies in Jilin Province was 50.64% and the SSR was associated with fertilization methods (p < 0.05). Comparing to in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI) (OR = 0.808, 95%CI: 0.681–0.958) decreased the percentage of male babies. Conclusions This study suggests that the SSR of ART births in Jilin Province was lower than the normal level and ICSI had a significant effect on SSR. Though we need more samples to study in the future, we still need to think about the impact of ICSI on SSR in ART.


2019 ◽  
Vol 73 (7) ◽  
pp. 660-667
Author(s):  
Omar Karlsson ◽  
Rockli Kim ◽  
William Joe ◽  
S V Subramanian

BackgroundIn India, excess female under-5 mortality is well documented. Under-5 mortality is also known to be patterned by socioeconomic factors. This study examines sex differentials and sex-specific wealth gradients in neonatal, postneonatal and child mortality in India.MethodsRepeated cross-sectional study of nationally representative samples of 298 955 children 0–60 months old from the National Family Health Surveys conducted in 2005–2006 and 2015–2016. The study used logistic regression models as well as Cox proportional hazards models.ResultsOverall, boys had greater neonatal mortality than girls and the difference increased between 2005–2006 and 2015–2016. Girls had greater postneonatal and child mortality, but the difference decreased between the surveys and was not statistically significant for child mortality in 2015–2016. A negative wealth gradient was found for all mortality outcomes. Neonatal mortality was persistently greater for boys. Girls had higher child mortality than boys at low levels of wealth and greater postneonatal mortality over much of the wealth distribution. The wealth gradient in neonatal mortality increased between surveys. Females had a stronger wealth gradient than boys for child mortality.ConclusionNot distinguishing between neonatal, postneonatal and child mortality masks important gender-specific and wealth-specific disparities in under-5 mortality in India. Substantial gains towards the Sustainable Development Goals can be made by combating neonatal mortality, especially at low levels of wealth. Although impressive improvements have been made in reducing the female disadvantage in postneonatal and child mortality, concerted engagements are necessary to eliminate the gender gap—especially in poor households and in north India.


PLoS ONE ◽  
2012 ◽  
Vol 7 (3) ◽  
pp. e33564 ◽  
Author(s):  
Yemisrach B. Okwaraji ◽  
Simon Cousens ◽  
Yemane Berhane ◽  
Kim Mulholland ◽  
Karen Edmond

2017 ◽  
Vol 20 (11) ◽  
pp. 1638-1647 ◽  
Author(s):  
Ragini Alok ◽  
Ragini Srivastava ◽  
Puneet Kumar ◽  
Siddharth K. Das ◽  
Girdhar G. Agarwal ◽  
...  

2020 ◽  
Author(s):  
Fulgence Kaboré ◽  
Baly Ouattara ◽  
Stéphanie Wendlassida Joelle Tiendrébéogo ◽  
Mohamed Diomandé ◽  
Charles Sougué ◽  
...  

Abstract Background: Neuropathic pain is defined as pain caused by injury or disease of the somatosensory nervous system. Our purpose was to study the frequency of neuropathic pain among common lumboradiculalgia patients in subsaharian Africa patients. Methods: This was a bicentric cross-sectional study from February 2015 to 30 July 2015 in the first center and then from February 2017 to 30 July 2017 in the second center, i.e. a duration of 6 months for each study site. All patients with a common lomboradiculalgie were included. DN4 questionnaire was used for the diagnosis of neuropathic pain.Results : Four hundred and nine patients with common lumboradiculalgia were included. There were 278 females (67.97%) and 131 males (32.03%), for a sex ratio of 0.47. The average age was 51.75 ± 13.84 years with extremes of 16 and 88 years. One hundred and seventy-five patients ( 42.8%) had NP. Statistical analysis showed a statistically significant association between the existence of NP and age over 60 years and the existence of radiculalgia. Conclusions: Our study confirms the high frequency of neuropathic pain during common lumboradiculalgia. Age over 60 years and Poorly systematized radiculalgia were associated to NP.


2021 ◽  
pp. 30-32
Author(s):  
Vikesh Gupta ◽  
Sukhjit Singh ◽  
Vineet Kumar ◽  
Pankaj Kanwar

Background: COVID-19 pandemic is a novel viral illness due to which an uncertainty has developed among the general public as well as the health care workers (HCWs) regarding the future of mankind. This has resulted in burnout among the HCWs which has been reported by researchers from different parts of the world. Method: A cross sectional study was done among health care workers (faculty members, residents, nurses and interns) working in different specialties of a tertiary care health centre of Northern India. A self-designed performa containing sociodemographic details along with “Burnout Self-Test” scale was used to obtain the prevalence of burnout among HCWs. Result: Among 192 participants, the signs of burnout were found in 148 participants (77.1%) and most had mild burnout 90 (46.88). Conclusion: Burnout amongst health care workers is high particularly in unmarried and female HCWs.


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