The technology of artificial pneumoperitoneum CT and its application in diagnosis of abdominal adhesion

AbstractTo retrospectively analyze the use of artificial pneumoperitoneum in CT scans, to explore its operation methods and technical points, and to lay the foundation for the widespread application of artificial pneumoperitoneum in CT. A total of 331 patients who underwent artificial pneumoperitoneum with CT angiography from January 1, 2013, to November 1, 2019, were recruited. All patients underwent standardized artificial pneumoperitoneum in the horizontal, left and right lateral, and prone positions during CT thin-layer scans of the abdomen and 3D reconstruction. Taking the surgical results as the gold standard, and using kappa test to verify the consistency of surgical results and imaging results. In all 331 patients, 43 patients had a normal peritoneal space, and 288 patients had an abnormal peritoneal space. And only 22 patients developed complications of subcutaneous emphysema, accounting for 6.6% of all 331 patients. In terms of the postoperative results, 28 were normal, and 303 were abnormal. The sensitivity, specificity and accuracy of CT diagnosis of abdominal adhesions using artificial pneumoperitoneum were 100%, 95.04%, and 95.46%, respectively. According to the Kappa consistency test, the imaging diagnosis from the CT scan with artificial pneumoperitoneum had a high consistency with the surgical results (kappa = 0.796, P < 0.05). The technique of artificial pneumoperitoneum CT is safe, reliable, highly practical, and proficient for obtaining good imaging results. It provides a good imaging basis for the diagnosis of intra-abdominal diseases, especially intra-abdominal adhesions.

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Diagnostic value of [18F]FDG PET/MRI for staging in patients with ovarian cancer

EJNMMI Research ◽

10.1186/s13550-020-00712-3 ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Hideaki Tsuyoshi ◽

Tetsuya Tsujikawa ◽

Shizuka Yamada ◽

Hidehiko Okazawa ◽

Yoshio Yoshida

Keyword(s):

Ovarian Cancer ◽

Fdg Pet ◽

Diagnostic Value ◽

Mri Contrast ◽

Diagnostic Potential ◽

Contrast Enhanced Ct ◽

Contrast Enhanced ◽

Imaging Results ◽

N Stage ◽

Sensitivity Specificity

Abstract Purpose To evaluate the diagnostic potential of PET/MRI with 2-[18F]fluoro-2-deoxy-d-glucose ([18F]FDG) in ovarian cancer. Materials and methods Participants comprised 103 patients with suspected ovarian cancer underwent pretreatment [18F]FDG PET/MRI, contrast-enhanced CT (ceCT) and pelvic dynamic contrast-enhanced MRI (ceMRI). Diagnostic performance of [18F]FDG PET/MRI and ceMRI for assessing the characterization and the extent of the primary tumor (T stage) and [18F]FDG PET/MRI and ceCT for assessing nodal (N stage) and distant (M stage) metastases was evaluated by two experienced readers. Histopathological and follow-up imaging results were used as the gold standard. The McNemar test was employed for statistical analysis. Results Accuracy for the characterization of suspected ovarian cancer was significantly better for [18F]FDG PET/MRI (92.5%) [95% confidence interval (CI) 0.84–0.95] than for ceMRI (80.6%) (95% CI 0.72–0.83) (p < 0.05). Accuracy for T status was 96.4% (95% CI 0.96–0.96) and 92.9% (95% CI 0.93–0.93) for [18F]FDG PET/MRI and ceMRI/ceCT, respectively. Patient-based accuracies for N and M status were 100% (95% CI 0.88–1.00) and 100% (95% CI 0.88–1.00) for [18F]FDG PET/MRI and 85.2% (95% CI 0.76–0.85) and 30.8% (95% CI 0.19–0.31) for ceCT and M staging representing significant differences (p < 0.01). Lesion-based sensitivity, specificity and accuracy for N status were 78.6% (95% CI 0.57–0.91), 95.7% (95% CI 0.93–0.97) and 93.9% (95% CI 0.89–0.97) for [18F]FDG PET/MRI and 42.9% (95% CI 0.24–0.58), 96.6% (95% CI 0.94–0.98) and 90.8% (95% CI 0.87–0.94) for ceCT. Conclusions [18F]FDG PET/MRI offers better sensitivity and specificity for the characterization and M staging than ceMRI and ceCT, and diagnostic value for T and N staging equivalent to ceMRI and ceCT, suggesting that [18F]FDG PET/MRI might represent a useful diagnostic alternative to conventional imaging modalities in ovarian cancer.

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The diagnosis of delirium in 80 emergency unit patients

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x1998000200002 ◽

1998 ◽

Vol 56 (2) ◽

pp. 176-183

Author(s):

AFONSO CARLOS NEVES ◽

RICARDO DE CASTRO CINTRA SESSO ◽

HENRIQUE BALLALAI FERRAZ ◽

SÍLVIO FRANCISCO ◽

JOÃO BAPTISTA DOS REIS-FILHO

Keyword(s):

Correct Diagnosis ◽

Diagnostic Testing ◽

Final Diagnosis ◽

Initial Diagnosis ◽

University Hospital ◽

Emergency Unit ◽

Predictive Values ◽

Kappa Test ◽

History Of ◽

Sensitivity Specificity

We evaluated the initial and final diagnosis of 80 patients with delirium arriving at the emergence unit of a university hospital in a large Brazilian city over a period of 30 months up to December 1991. The diagnosis was based on the DSM-IIIR criteria. Patients with a known history of head trauma or epileptic seizure and patients younger than 13 years were excluded. Only patients with a disease of up to 7 days were included.The patients were subdivided into four etiologic groups: vascular; associated with the use of alcohol; infectious-parasitic; miscellaneous.The results showed a rate of correct diagnosis ranging from 65 to 80% with the use of kappa test (standard good to excelent). Sensitivity, specificity, positive predictive and negative predictive values had results showing different conditions for initial diagnosis in each group. This study can help the initial diagnosis of delirium and the choice for diagnostic testing.

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Comparison of revised EWGSOP2 criteria of sarcopenia in patients with cancer using different parameters of muscle mass

PLoS ONE ◽

10.1371/journal.pone.0257446 ◽

2021 ◽

Vol 16 (9) ◽

pp. e0257446

Author(s):

Ana Paula Trussardi Fayh ◽

Iasmin Matias de Sousa

Keyword(s):

Cancer Patients ◽

Muscle Mass ◽

Handgrip Strength ◽

Lumbar Vertebra ◽

Cross Sectional Study ◽

Diagnostic Methods ◽

Cross Sectional ◽

Kappa Test ◽

European Working ◽

Sensitivity Specificity

Calf circumference (CC) has been established as a marker of muscle mass (MM) with good performance for predicting survival in individuals with cancer. The study aims to determine the prevalence of sarcopenia according to the European Working Group on Sarcopenia in Older People 2 (EWGSOP2) criteria and to evaluate the accuracy of sarcopenia using low CC relative to MM assessment by computed tomography (CT) at third lumbar vertebra level (L3) as a reference. Cross-sectional study with cancer patients aged ≥ 60 years. Data included socio-demographic, clinical and anthropometric variables. MM was assessed by CC and by CT images at the L3. Sarcopenia was diagnosed according to the EWGSOP2 criteria: a) low handgrip strength (HGS) + reduced MM evaluated by CT; and b) low HGS + low CC. Pearson’s correlation, accuracy, sensitivity, specificity, positive predictive and negative predictive value were analyzed. A total of 108 patients were evaluated, age of 70.6 ± 7.4 years (mean ± standard deviation). The prevalence of sarcopenia was of 24.1% (low MM) and 25.9% (low CC). The Kappa test showed a substantial agreement (K = 0.704), 81% sensitivity, and 92% specificity. Although the EWGSOP2 advises that we should use CC measures in the algorithm for sarcopenia when no other MM diagnostic methods are available, the findings allow the use of CC instead of MM by CT in cancer patients.

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Diagnostic value of [18F]FDG PET/MRI for staging in patients with ovarian cancer

10.21203/rs.3.rs-46817/v3 ◽

2020 ◽

Author(s):

Hideaki Tsuyoshi ◽

Tetsuya Tsujikawa ◽

Shizuka Yamada ◽

Hidehiko Okazawa ◽

Yoshio Yoshida

Keyword(s):

Ovarian Cancer ◽

Fdg Pet ◽

Diagnostic Value ◽

Mri Contrast ◽

Diagnostic Potential ◽

Contrast Enhanced Ct ◽

Contrast Enhanced ◽

Imaging Results ◽

N Stage ◽

Sensitivity Specificity

Abstract Purpose: To evaluate the diagnostic potential of PET/MRI with 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG) in ovarian cancer.Materials and Methods: Participants comprised 103 patients with suspected ovarian cancer underwent pretreatment [18F]FDG PET/MRI, contrast-enhanced CT (ceCT) and pelvic dynamic contrast-enhanced MRI (ceMRI). Diagnostic performance of [18F]FDG PET/MRI and ceMRI for assessing the characterization and the extent of the primary tumor (T stage) and [18F]FDG PET/MRI and ceCT for assessing nodal (N stage) and distant (M stage) metastases was evaluated by two experienced readers. Histopathological and follow-up imaging results were used as the gold standard. The McNemar test was employed for statistical analysis.Results: Accuracy for the characterization of suspected ovarian cancer was significantly better for [18F]FDG PET/MRI (92.5%) [95% confidence interval (CI) 0.84–0.95] than for ceMRI (80.6%) (95%CI 0.72–0.83) (p <0.05). Accuracy for T status was 96.4% (95%CI 0.96–0.96) and 92.9% (95%CI 0.93–0.93) for [18F]FDG PET/MRI and ceMRI/ceCT, respectively. Patient-based accuracies for N and M status were 100% (95%CI 0.88–1.00) and 100% (95%CI 0.88–1.00) for [18F]FDG PET/MRI and 85.2% (95%CI 0.76–0.85) and 30.8% (95%CI 0.19–0.31) for ceCT and M staging representing significant differences (p<0.01). Lesion-based sensitivity, specificity and accuracy for N status were 78.6% (95%CI 0.57–0.91), 95.7% (95%CI 0.93–0.97) and 93.9% (95%CI 0.89–0.97) for [18F]FDG PET/MRI and 42.9% (95%CI 0.24–0.58), 96.6% (95%CI 0.94–0.98) and 90.8% (95%CI 0.87–0.94) for ceCT. Conclusions: [18F]FDG PET/MRI offers better sensitivity and specificity for the characterization and M staging than ceMRI and ceCT, and diagnostic value for T and N staging equivalent to ceMRI and ceCT, suggesting that [18F]FDG PET/MRI might represent a useful diagnostic alternative to conventional imaging modalities in ovarian cancer.

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Diagnostic Value and Pathological Correlation of Narrow Band Imaging Classification in Laryngeal Lesions

Ear Nose & Throat Journal ◽

10.1177/0145561320925327 ◽

2020 ◽

pp. 014556132092532 ◽

Cited By ~ 1

Author(s):

Chuanyao Lin ◽

Sisi Zhang ◽

Ling Lu ◽

Maohua Wang ◽

Xiaoyun Qian

Keyword(s):

Predictive Value ◽

Narrow Band ◽

Narrow Band Imaging ◽

Diagnostic Value ◽

Pathological Correlation ◽

Laryngeal Lesions ◽

Loop Pattern ◽

Malignant Lesions ◽

High Consistency ◽

Sensitivity Specificity

Objectives: To explore the diagnostic value and pathological correlation of narrow band imaging (NBI) classification in laryngeal lesions. Methods: A total of 112 patients (123 lesions) with laryngeal lesions from July 2018 to May 2019 were selected in this study. All patients were examined by NBI and white light imaging endoscopy. The NBI endoscopy was applied to classify the observed lesion sites according to intraepithelial papillary capillary loop pattern. The gold standard of diagnosis was pathological results. To evaluate the consistency of NBI classification and pathological results. Results: The sensitivity, specificity, positive predictive value, and negative predictive value of the diagnosis for benign, precancerous, and malignant lesions under the NBI endoscopy were 90.91%, 81.19%, 74.07%, 85.42%; 41.67%, 92.93%, 58.82%, 86.79%; and 93.51%, 65.22%, 91.14%, 68.18%, respectively. There was a high consistency between NBI classification and pathological results (κ = 0.679, P < .001). Conclusions: The NBI classification can improve the accuracy of the diagnosis of laryngeal lesions. It is important for early diagnosis and treatment of vocal cord leukoplakia and laryngeal cancer.

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SPIO-enhanced MR imaging at 3T for accurate diagnosis of sentinel node metastases to avoid sentinel node biopsy in patients with breast cancer.

Journal of Clinical Oncology ◽

10.1200/jco.2014.32.26_suppl.68 ◽

2014 ◽

Vol 32 (26_suppl) ◽

pp. 68-68

Author(s):

Kazuyoshi Motomura ◽

Takahiro Nakayama ◽

Yasuhiro Tamaki ◽

Yuri Ito ◽

Katsuyuki Nakanishi

Keyword(s):

Breast Cancer ◽

Mr Imaging ◽

Sentinel Node ◽

Sentinel Node Biopsy ◽

Sentinel Nodes ◽

Node Biopsy ◽

Imaging Results ◽

Node Metastases ◽

The Mean ◽

Sensitivity Specificity

68 Background: We previously demonstrated the usefulness of SPIO-enhanced MR imaging at 1.5T for the detection of metastases in sentinel nodes identified by computed tomography lymphography (CT-LG) in patients with breast cancer (Ann Surg Oncol 2011, ASCO 2012). The aim of this study was to evaluate whether SPIO-enhanced MR imaging at 3T improved the diagnostic accuracy for the detection of metastases in sentinel nodes. Moreover, these results were compared with those of the diagnosis using CT-LG according to the size criteria. Methods: Seventy patients with breast cancer and clinically negative nodes were included. Sentinel nodes identified by CT-LG were evaluated prospectively using SPIO-enhanced MR imaging at 3T. Sentinel node size was measured on CT-LG and a node larger than 5 mm in short axis diameter was considered metastatic. Sentinel nodes localized by CT-LG were removed, and imaging results and histopathological findings were compared. Results: The mean patient age was 55 years (range, 29-78). Sentinel nodes were identified by CT-LG successfully in 69 (98.6%) of 70 patients. The mean number of sentinel nodes identified by CT-LG was 1.4 (range, 1-3). All 19 patients with positive sentinel nodes definitively diagnosed by pathology demonstrated metastases on SPIO-enhanced MR imaging. Forty-eight of 50 patients with negative sentinel nodes definitively diagnosed by pathology were non-metastatic on the imaging studies. The sensitivity, specificity and accuracy of MR imaging for the diagnosis of sentinel node metastases were 100%, 96.0%, and 97.1%, respectively, on a patient-by-patient basis. Those of CT-LG were 78.9%, 56.0%, 62.3%, respectively. The specificity and accuracy of MR imaging were superior to those of CT-LG (McNemar test; p < .0001 and = .0015, respectively). Conclusions: SPIO-enhanced MR imaging at 3T can accurately diagnose the sentinel node metastases, and therefore sentinel node biopsy may not be required for most patients with breast cancer.

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Full Waveform Inversions of Borehole Transient Electromagnetic Virtual Wave Fields and Potential Applications

Journal of Environmental and Engineering Geophysics ◽

10.2113/jeeg19-065 ◽

2020 ◽

Vol 25 (2) ◽

pp. 211-222

Author(s):

Fan Tao ◽

Qi Zhipeng ◽

Yan Bin ◽

Zhao Zhao ◽

Wang Bingchun ◽

...

Keyword(s):

Wave Field ◽

Shanxi Province ◽

Small Scale ◽

Detection Accuracy ◽

Dynamic Correction ◽

Wave Fields ◽

Full Waveform ◽

Transient Electromagnetic ◽

Good Imaging ◽

Imaging Results

The transient electromagnetic method (TEM) for boreholes uses fixed source loops to launch at excavation faces, and is able to realize the mobile reception of secondary fields in the boreholes and detections of low-resistance hazards. This method is known as high detection accuracy, due to the fact that the receiving points are close to the anomalies. However, the interpretation method for this device has not yet been perfected. The present study's goal was to realize the interpretations of boreholes TEM based on inverse transform algorithms of the TEM wave-fields and full waveform inversions. It was found that under the conditions of transient electromagnetic virtual wave-fields, the characteristics of the virtual wave-field time-distance curves of the two-dimensional device could be examined, and a corresponding dynamic correction algorithm was successfully obtained. The wave-field velocities were analyzed using an equivalent conductive plane method. Additionally, the pseudo-seismic inversions of the tunnel-borehole TEM data were realized using full waveform inversion technology. Then, the inversion results of the three-dimensional numerical simulations, flume physical simulations, and downhole field simulations were calculated. It was observed that good imaging results had been obtained for small-scale borehole radial anomalies. Finally, the proposed method was applied to the engineering practices in an underground coal mine in Shanxi Province. The practicability and effectiveness of the proposed method in the fine detection of the properties, forms, and scale of water-logged goaf roadways were successfully tested in the field. The research results indicated that the roadway-borehole transient electromagnetic detection method was complementary to the underground geophysical exploration and drilling, and could be effectively applied in the detection of water-logged goaf roadways.

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Efficiency of Abdominal Ultrasound and Computer Tomography in Diagnostic and Differential Diagnostic of Focal Liver Lesions

Acta Chirurgica Latviensis ◽

10.1515/chilat-2016-0004 ◽

2015 ◽

Vol 15 (1) ◽

pp. 18-22

Author(s):

Janis Vilmanis ◽

Arturs Ozolins ◽

Janis Gardovskis

Keyword(s):

Liver Biopsy ◽

Ct Scan ◽

Computer Tomography ◽

Abdominal Ultrasound ◽

Focal Liver Lesions ◽

Imaging Method ◽

Liver Lesions ◽

Good Imaging ◽

Imaging Results ◽

Hepatic Lesions

SummaryIntroduction. The liver is a parenchimal abdominal organ with wide variety of primary benign or malignant tumors as well as metastatic tumors.Aim of the study. Was to evaluate the informativity and usefulness of abdominal ultrasound (US) and computer tomography (CT) imaging results in diagnostics of focal liver lesions.Material and methods. The study was conducted in Pauls Stradins Clinical University Hospital. Retrospective analysis of 126 patients with focal liver lesions was performed in the time period of 5 years (2009 till 2014). The medical records of patients with focal liver lesions were analyzed. Primary diagnosis detected by US or CT was evaluated and compared with final morphology after surgical operation or liver biopsy. The obtained results were expressed in percent and analyzed. Sensitivity and specificity of CT scan to detect malignant hepatic lesions was estimated and expressed as percentage with 95% confidence interval.Results. A total of 126 patients with diagnosed liver lesions were included in the study. 96 patients were in the group with performed liver CT scans, with median age of 58.9 years. 30 patients were included in the group with liver US, with median age of 60.1 years. Liver biopsy under US control was performed for 95 patients, but surgical operations with liver resections for 31 patients. 86 patients had malignant liver lesions, but 40 had benign liver lesions. In the US group primary and final diagnosis agreement was in 26 (87%) cases, but diagnosis disagreement in 4 (13%) cases. Diagnosis disagreement was found in 26 (27.1%) cases in the CT group, but agreement was in 70 (72.9%) cases. Overall sensitivity of CT to detect malignant hepatic lesions was 95.2% (95%CI 86.7-98.3%) and specificity was 64.7% (95%CI 47.9-78.5%).Conclusions. CT is a good imaging method for detection of focal liver lesions. In case of unclear diagnosis, percutaneous liver puncture biopsy is recommended. It is mandatory to develop a unified CT scan and US investigation protocol to improve the quality of investigation as well as further treatment tactics.

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Will Fluoroscopic Follow-up after Stent-Assisted Coiling of Cerebral Aneurysms Provide Information on Recanalization?

Interventional Neuroradiology ◽

10.15274/inr-2014-10062 ◽

2014 ◽

Vol 20 (6) ◽

pp. 693-703 ◽

Cited By ~ 1

Author(s):

Hyun Ho Oh ◽

Cheolkyu Jung ◽

Tae Hong Lee ◽

Bae Ju Kwon ◽

Young Kim ◽

...

Keyword(s):

Sensitivity And Specificity ◽

Imaging Modality ◽

False Negative ◽

Cerebral Aneurysms ◽

High Sensitivity ◽

Outpatient Basis ◽

Good Imaging ◽

Sensitivity Specificity ◽

Interreader Agreement

Fluoroscopic images for comparison (FICs) can be easily obtained for follow-up on an outpatient basis. This study retrospectively assessed the diagnostic performance of a set of FICs for evaluation of recanalization after stent-assisted coiling, with digital subtraction angiography (DSA) as the reference standard. A total of 124 patients harboring 144 stent-assisted coiled aneurysms were included. At least one month postembolization they underwent follow-up angiograms comprising a routine frontal and lateral DSA and a working-angle DSA. For analysis, FICs should be compared with the mask images of postprocedural DSAs to find recanalization. Instead of FIC acquisition, the mask images of follow-up DSAs were taken as a substitute because of the same view-making processes as FICs, full availability, and perfect coincidence with follow-up DSAs. Two independent readers evaluated a set of 169 FICs and DSA images for the presence of recanalization one month apart. Sensitivity, specificity, and interreader agreement were determined. Recanalization occurred in 24 (14.2%) cases. Of these, nine (5.3%) cases were found to have significant recanalization in need of retreatment. Sensitivity and specificity rates were 79.2% (19 of 24) and 95.9% (139 of 145) respectively for reader 1, and 66.7% (16 of 24) and 97.9% (142 of 145) for reader 2. Minimal recanalization was identified in seven out of all eight false negative cases. Excluding minimally recanalized cases in no need for retreatment from the recanalization group, calculation resulted in high sensitivity and specificity of over 94% for both readers. Interreader agreement between the two readers was excellent (96.4%; κ = 0.84). FICs may be a good imaging modality to detect significant recanalization of stent-assisted coiled aneurysms.

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P.148 Children and teenagers with hydrocephalus: Are narrowed dural sinuses better predictors of shunt-failure than ventriculomegaly?

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques ◽

10.1017/cjn.2021.424 ◽

2021 ◽

Vol 48 (s3) ◽

pp. S62-S62

Author(s):

B Rohr ◽

J Sorensen ◽

B Gong ◽

O Jansen ◽

A Rohr

Keyword(s):

Gold Standard ◽

Dural Sinus ◽

Fisher Exact Test ◽

Shunt Failure ◽

Cross Sectional ◽

Exact Test ◽

Dural Sinuses ◽

Kappa Test ◽

Operative Findings ◽

Sensitivity Specificity

Background: Intracranial hypertension secondary to shunt-failure is a feared complication requiring cross-sectional imaging for diagnosis. We compared dural sinus narrowing and ventriculomegaly as predictors of shunt-failure. Methods: 60 head MRIs and 60 MR venographies of hydrocephalus patients age 0-18 years (n=25) were analyzed. MRI studies were included when f/u clinical data combined with intra-operative findings proved shunt-failure (positive Gold standard) or when MRI was available when the child was well (negative Gold standard). The absence or presence of concerning hydrocephalus was diagnosed. On MRV, the major dural sinuses were independently analyzed with respect to >50% narrowing, suggesting compression by increased CSF pressure. Ventriculomegaly and significant dural sinus narrowing was correlated to the presence/absence of shunt failure as per Gold standard. Results: Sinus narrowing substantially correlated with proven shunt-failure (Cohen’s kappa test 0.635/p<=0.00001 as per Fisher exact test) while ventriculomegaly correlated poorly (0.258/p=0.0751). Sensitivity/specificity was 0.69/0.92 for sinus narrowing and 0.43/0.81 for ventriculomegaly. Conclusions: In this patient cohort, dural sinus narrowing more reliably predicted shunt-failure compared to ventriculomegaly.

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