scholarly journals Metabolomics and cancer preventive behaviors in the BC Generations Project

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
J. Qi ◽  
J. J. Spinelli ◽  
T. J. B. Dummer ◽  
P. Bhatti ◽  
M. C. Playdon ◽  
...  

AbstractMetabolomics can detect metabolic shifts resulting from lifestyle behaviors and may provide insight on the relevance of changes to carcinogenesis. We used non-targeted nuclear magnetic resonance to examine associations between metabolic measures and cancer preventive behaviors in 1319 participants (50% male, mean age 54 years) from the BC Generations Project. Behaviors were dichotomized: BMI < 25 kg/m2, ≥ 5 servings of fruits or vegetables/day, ≤ 2 alcoholic drinks/day for men or 1 drink/day for women and ≥ 30 min of moderate or vigorous physical activity/day. Linear regression was used to estimate coefficients and 95% confidence intervals with a false discovery rate (FDR) of 0.10. Of the 218 metabolic measures, 173, 103, 71 and 6 were associated with BMI, fruits and vegetables, alcohol consumption and physical activity. Notable findings included negative associations between glycoprotein acetyls, an inflammation-related metabolite with lower BMI and greater fruit and vegetable consumption, a positive association between polyunsaturated fatty acids and fruit and vegetable consumption and positive associations between high-density lipoprotein subclasses with lower BMI. These findings provide insight into metabolic alterations in the context of cancer prevention and the diverse biological pathways they are involved in. In particular, behaviors related to BMI, fruit and vegetable and alcohol consumption had a large metabolic impact.

2018 ◽  
Vol 26 (2) ◽  
pp. 84-91 ◽  
Author(s):  
Claire Stevens ◽  
Samuel G Smith ◽  
Charlotte Vrinten ◽  
Jo Waller ◽  
Rebecca J Beeken

Objectives Population-based cancer screening has been described as a teachable moment for behaviour change. This research examined the effect of faecal occult blood testing (FOBT) participation on smoking, alcohol consumption, fruit and vegetable consumption and physical activity. Setting Data were from screening-naïve men within the English Longitudinal Study of Ageing, receiving their first FOBT invitation (n = 774). Four waves of data were included in analyses (wave 4, 2008/2009 – wave 7, 2014/2015). Baseline data were from the wave prior to FOBT invitation, and follow-up data were from the next consecutive wave (two years later). Methods The effects of FOBT participation, time and group-by-time interactions on health behaviours were investigated using generalised estimating equations. Almost two-thirds of the sample (62.5%; n = 484) had participated in FOBT. Results Screening participants were less likely to smoke (odds ratio (OR): 0.45, 95% confidence interval (CI): 0.29–0.68) and more likely to meet fruit and vegetable consumption guidelines (OR: 1.70, 95% CI: 1.14–2.55). Smoking decreased over time (OR: 0.74, 95% CI: 0.62–0.89), but adherence to alcohol guidelines also decreased (OR: 0.71, 95% CI: 0.53–0.91). A group-by-time interaction was found for vigorous physical activity; the odds of taking part in vigorous physical activity increased for FOBT participants, but decreased for non-participants (OR: 1.40, 95% CI: 1.01–1.95). Conclusions This research provides tentative support for FOBT as a teachable moment for increasing vigorous physical activity. However, overall, there was limited evidence for spontaneous improvement in multiple health behaviours following participation.


HortScience ◽  
2004 ◽  
Vol 39 (4) ◽  
pp. 783A-783
Author(s):  
Mu-Chuan Lin ◽  
Candice Shoemaker* ◽  
Nancy Gyurcsik

Older adults are not sufficiently physically active and do not consume sufficient fruits and vegetables to achieve health benefits, such as an improved health-related quality of life (HRQL). As a result, an innovative gardening intervention, comprised of stretching exercises, the teaching of home garden knowledge and skills, and the preparation and taste testing of fruits and vegetables, was developed to target increased: (a) confidence to garden and to consume fruits and vegetables, (b) physical activity, (c) fruit and vegetable consumption, and (d) HRQL. Seven older adults, aged 60 years or older, participated in the gardening intervention and 10 older adults participated in the control group during the fall. Measures of confidence, physical activity (i.e., gardening), fruit and vegetable consumption, and HRQL were obtained at baseline and at the end of the 10-week program. Findings revealed that, at baseline, intervention participants had significantly higher confidence to garden compared to control participants but at end-program intervention and control participants did not significantly differ in any of the outcome variables. Bivariate findings also revealed that intervention participants who had higher confidence to garden or to consume fruits and vegetables at baseline also gardened more at end-program. Thus, interventions targeting confidence to garden and to consume fruits and vegetables may be effective in improving gardening (i.e., physical activity) behavior. Findings also suggest that seasonal change may be one influential moderator of the gardening program on confidence and gardening and fruit and vegetable consumption behavior change. Future research should examine the impact of the program in different seasons to clarify the effects.


Nutrients ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 1974 ◽  
Author(s):  
Jared McGuirt ◽  
Stephanie Jilcott Pitts ◽  
Alison Gustafson

Because supermarkets are a critical part of the community food environment, the purpose of this paper is to examine the association between accessibility to the supermarket where participants were surveyed, frequency of shopping at the supermarket, and self-reported and objectively-assessed fruit and vegetable consumption. Accessibility was assessed using Geographic Information Systems (GIS) measured distance and multiple versions of the modified Retail Food Environment Index (mRFEI), including a localized road network buffer version. Frequency of shopping was assessed using self-report. The National Cancer Institute Fruit and Vegetable screener was used to calculate daily servings of fruits and vegetables. Skin carotenoids were assessed using the “Veggie Meter™” which utilizes reflection spectroscopy to non-invasively assess skin carotenoids as an objective measure of fruit and vegetable consumption. Bivariate and multivariable statistics were used to examine the associations in RStudio. There was a positive association between skin carotenoids and the Special Supplemental Nutrition Program for Women Infants and Children (WIC) and mRFEI scores, suggesting that WIC participation and a healthier food environment were associated with objectively-assessed fruit and vegetable consumption (skin carotenoids). Future research should examine these associations using longitudinal study designs and larger sample sizes.


Nutrients ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 4467
Author(s):  
Björg Helgadóttir ◽  
Hanna Baurén ◽  
Karin Kjellenberg ◽  
Örjan Ekblom ◽  
Gisela Nyberg

This study explored whether breakfast habits were associated with intake of fruits and vegetables, minutes in moderate-to-vigorous physical activity (MVPA), minutes spent sedentary, and screen time among adolescents. Cross-sectional data were collected among 13–14-year-old boys and girls (n = 1139). Breakfast habits and screen time were determined via questionnaire, fruit and vegetable intake were determined through dietary recall, and physical activity and sedentary time were determined via accelerometers. Multilevel mixed models and general estimation equation models were applied. Almost 40% of participants skipped breakfast at least one day of the week. Participants with irregular breakfast habits on weekdays had lower fruit and vegetable consumption by 26.7 g (95% CI = −49.3, −5.9) while irregular breakfast habits during the whole week were associated with higher levels of screen time (OR = 1.5, 95% CI = 1.1, 2.1) compared to regular breakfast habits. Girls with irregular breakfast habits on weekdays had 7.7 min more sedentary time (95% CI = 0.8, 15.7) than girls with regular breakfast habits, while the opposite was found in boys (β = −13.3, 95% CI = −25.3, −2.6)). No significant associations were found for MVPA. Regular breakfast habits should be encouraged, as they might contribute to a higher intake of fruit and vegetables and are associated with lower levels of screen time, although further studies are necessary to establish causation.


2011 ◽  
Vol 16 (5) ◽  
pp. 864-872 ◽  
Author(s):  
David Doku ◽  
Leena Koivusilta ◽  
Susanna Raisamo ◽  
Arja Rimpelä

AbstractObjectiveFew studies have investigated the association between adolescents’ socio-economic status (SES) and health behaviours in developing countries. Socio-economic differences in breakfast eating, fruit and vegetable consumption and physical activity were investigated among Ghanaian adolescents.DesignA school-based survey of 12–18-year-olds (n 1195, response rate 89·7 %) was conducted in 2008. Logistic regression analyses were applied to study the associations between breakfast eating, fruit and vegetable consumption and physical activity, and SES.SettingSouthern Ghana, West Africa.SubjectsSchool pupils aged 12–18 years.ResultsOf all adolescents, 31 % took breakfast less than 4 d/week, over half (56 %) and 48 %, respectively, rarely ate fruits and vegetables. Younger adolescents (12–15-year-olds) consumed fruits and vegetables frequently compared with older ones (16–18-year-olds). Boys were more likely to participate in physical activity than girls. The probability of frequent breakfast eating was higher in adolescents from more affluent backgrounds than in those from less affluent ones. Compared with those whose mothers were illiterate, both tertiary and primary maternal educational attainment increased the probability of frequent fruit intake. Similarly, tertiary educational attainment increased the likelihood of frequent vegetable intake. Compared with those with unemployed mothers, mothers’ low employment grade was related to higher probability of frequent fruit intake. High school performance was associated with frequent fruit intake, whereas high or medium school performance increased the likelihood of vegetable intake compared with low school performance.ConclusionsInterventions are needed to improve breakfast intake, fruit and vegetable consumption and physical activity in order to prevent degenerative diseases among Ghanaian adolescents.


2008 ◽  
Vol 6 (2) ◽  
pp. 61-72 ◽  
Author(s):  
Joan Faith Epstein ◽  
Sharon Sugerman ◽  
Patrick Mitchell ◽  
Marta Induni

Diets high in fruits and vegetables and participation in regular physical activity are associated with a lower risk for several chronic diseases and conditions. The present study analyzed the combined prevalence of these two activities by race/ethnicity and gender among adults in California and among adults in California at or below 130% of the federal poverty level (FPL), using self-reported data from the 2005 and 2006 California Behavioral Risk Factor Surveillance System (BRFSS). Findings for California were similar to findings for the nation, showing gender and racial/ethnic differences for each of these variables, singly and in combination. Also, low-income men had a significantly lower prevalence of goal-level fruit and vegetable consumption than did low-income women. Although some demographic disparities are evident among Californians, the prevalence of achievement of two key healthy lifestyle behaviors concurrently remains quite low. These results emphasize the need for promoting diets high in fruits and vegetables and regular physical activity among all Californians.


2021 ◽  
pp. 1-3
Author(s):  
Joreintje Dingena Mackenbach

Abstract I reflect upon the potential reasons why American low-income households do not spend an optimal proportion of their food budgets on fruits and vegetables, even though this would allow them to meet the recommended levels of fruit and vegetable consumption. Other priorities than health, automatic decision-making processes and access to healthy foods play a role, but solutions for the persistent socio-economic inequalities in diet should be sought in the wider food system which promotes cheap, mass-produced foods. I argue that, ultimately, healthy eating is not a matter of prioritisation by individual households but by policymakers.


Author(s):  
Irma Nuraeni ◽  
Hamam Hadi ◽  
Yhona Paratmanitya

ABSTRACT<br /><br />Background: Curently, Indonesia has double burden problems nutrition, such as malnutrition and over nutrition. Overnutrition or obesity are not just happening in adults only, but also can occur in childhood. If the problem of obesity in children and adolescents cannot be resolved, it can be infl uenced obese in adulthood then potentially to have noncommunicable diseases, such as cardiovascular disease, hypertension and diabetes mellitus. Prevalence of obesity in<br />children at Yogyakarta Province increases year by year (1;2). Obesity was caused by an imbalance in energy intake and<br />energy expenditure. Children tend to consume high energy-dense, sweet  taste meal, high fat foods and less dietary fiber from fruits and vegetables. Several studies showed that there was increasing in risk of obesity from someone who have less consumption of fruits and vegetables.<br /><br />Objective:<br />To determine differences in frequency and amount of fruit and vegetable consumption in elementary school children obese and non-obese at Yogyakarta Municipality and  District of Bantul and to find out the risk of obesity in children who have less consumption of fruits and vegetables. <br /><br />Methods:<br />The study design was a case-control, 244 samples as cases (obese children) and 244 controls (non-obesechildren). The subject of this study was children aged 6-12 years who were seated in class 1 to class 5 elementary schools at Yogyakarta Municipality and District of Bantul. Identity data obtained from a structured questionnaire respondent, frequency and amount of fruit and vegetable consumption were taken from Semi Quantitative Food Frequency Questioner(SQFFQ).Then the results analyzed using statistical test.<br /><br />Results: <br />Statistical test showed that there were significant differences (p&lt;0,05) in the frequency and number of fruit and vegetable consumption in obese and non-obese elementary school children at Yogyakarta Municipality and District of Bantul. Multivariate analysis after controlled by gender and energy intake, showed that obese  children who rarely consuming fruits (&lt;7 times/week) (OR=2,24, 95%CI: 1.53-3.28), rarely consuming vegetables (&lt;7 times/week) (OR=2,52, 95%CI: 1,70-3,73), and consuming fruits and vegetables less than 5 servings/day (equivalent to 400 g/day) (OR= 4,59, 95%CI:2,11-10,00) were greater risk for being obesity.<br /><br />Conclusion:<br />Obese children had rarely and less consume of fruits and vegetables than that did in non-obese children at Yogyakarta Municipality and District of Bantul. The children rarely and less consuming fruits and vegetables increased the risk of obesity.<br /><br />KEYWORDS: children obesity, vegetable, fruit<br /><br />ABSTRAK<br /><br />Latar Belakang: Indonesia saat ini mengalami masalah gizi ganda, yaitu masalah gizi kurang dan gizi lebih. Kelebihan  gizi atau obesitas pada anak dan remaja apabila tidak diatasi maka berdampak menjadi obesitas pada masa dewasa yang berpotensi mengalami penyakit tidak menular, seperti jantung, hipertensi dan diabetes mellitus. Prevalensi obesitas pada anak di Provinsi Daerah Istimewa Yogyakarta mengalami peningkatan dari tahun ke tahun (1; 2). Obesitas disebabkan ketidakseimbangan antara masukan dengan keluaran energi. Anak cenderung mengkonsumsi padat energi yang berasa manis dan berlemak tinggi serta makanan kurang serat dari buah dan sayur. Beberapa penelitian menunjukkan peningkatan risiko obesitas pada orang yang kurang konsumsi buah dan sayur.<br /><br />Tujuan: Untuk mengetahui perbedaan frekuensi dan jumlah konsumsi buah dan sayur pada anak SD obes dan tidak obes di Kota Yogyakarta dan Kabupaten Bantul serta peran konsumsi buah dan sayur terhadap kejadian obesitas. <br /><br />Metode: Rancangan penelitian ini adalah case-control, 244 kasus (anak obes) dan 244 kontrol (anak tidak obes). Subjek penelitian adalah anak usia 6-12 tahun yang duduk di kelas 1 hingga kelas 5 sekolah dasar di Kota Yogyakarta dan di Kabupaten Bantul. Data identitas diperoleh dari kuesioner terstruktur, sedangkan data frekuensi dan jumlah konsumsi buah dan sayur diperoleh dari semikuantitatif FFQ. Hasilnya kemudian dianalisis menggunakan uji statistik.<br /><br />Hasil: Pada anak SD obes dan tidak obes di Kota Yogyakarta dan Kabupaten Bantul terdapat perbedaan yang signifikan(p&lt;0,05) dalam frekuensi dan jumlah konsumsi buah dan sayur. Hasil analisis multivariat setelah dikontrol dengan jenis kelamin dan asupan energi menunjukkan bahwa anak SD obes yang mengkonsumsi buah jarang (&lt; 7 kali/minggu) (OR=2,24, 95%CI:1,53-3,28), frekuensi konsumsi sayur jarang (&lt;7 kali/minggu) (OR=2,52, 95%CI: 1,70-3,73), jumlah konsumsi buah dan sayur kurang dari 5 porsi/hari atau setara dengan 400 gr/hari (OR=4,59, 95%CI: 2,11-10,00) berisiko lebih besar untuk terjadinya obesitas. <br /><br />Kesimpulan: Anak SD yang obes lebih jarang dan lebih sedikit mengkonsumsi buah dan sayur dibandingkan dengan anak SD yang tidak obes di Kota Yogyakarta dan Kabupaten Bantul. Anak yang jarang dan sedikit mengkonsumsi buah dan sayur dapat meningkatkan risiko terjadinya obesitas.<br /><br />KATA KUNCI: obesitas anak, sayur, buah


2007 ◽  
Vol 5 (2) ◽  
pp. 157-162 ◽  
Author(s):  
Richard R. Rosenkranz ◽  
Karly S. Geller ◽  
David. A. Dzewaltowski

Many children do not meet current guidelines for physical activity and fruit and vegetable consumption, two areas of health-related behavior with links to obesity. Objective: To examine child and parent perceptions of child proxy agency, home physical activity opportunity, and home accessibility of fruits and vegetables. Methods: Dyads (N = 117) of parents and children completed questionnaires for this cross-sectional study. Results: For child proxy agency, fruits and vegetables accessibility, and physical activity opportunity, the parent and child perceptions were significantly related. Parent ratings of physical activity opportunity and child proxy agency were significantly greater than child ratings. Perceptions of both parents and children for proxy agency were associated with fruits and vegetables accessibility and physical activity opportunity. Conclusions: Parents and children hold similar, yet distinct perceptions of physical activity opportunity and child proxy agency. Perceptions of child proxy agency are associated with obesity-related home environmental characteristics.


Sign in / Sign up

Export Citation Format

Share Document