scholarly journals The severity of malnutrition in children with epidermolysis bullosa correlates with disease severity

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Seema Manjunath ◽  
Rahul Mahajan ◽  
Dipankar De ◽  
Sanjeev Handa ◽  
Savita Attri ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Disease Severity ◽  
Epidermolysis Bullosa ◽  
Receiver Operating Curve ◽  
Severe Malnutrition ◽  
Second Phase ◽  
Anthropometric Parameters ◽  
Indian Children ◽  
Z Scores ◽  
Bivariate Regression Analysis

AbstractWHO defines malnutrition as severe if the z-scores are less than − 3 Standard deviation (SD), moderate if between − 2 and − 3 SD and mild if between − 2 SD to – 1 SD. This study was aimed to assess nutritional aspects of Indian children suffering from EB and to evaluate the effect of severity of EB on the severity of malnutrition. In this study, pediatric EB patients were evaluated prospectively for baseline nutritional status using anthropometric parameters and WHO growth charts, and its correlation with disease severity using instrument for Scoring Clinical Outcomes for Research of Epidermolysis Bullosa-iscorEB. In second phase, an individualized diet chart was given to meet the energy, protein and micronutrients needs and its effects were observed after 6 months. The median age of participants was 3 years (IQR-9). Of 57 patients, malnutrition was seen in 40.35% patients (22.81%-moderate and 17.54%-severe), and significantly correlated with iscorEB (r = 0.45, p < 0.0001). On bivariate regression analysis, iscorEB was independently associated with moderate-to-severe malnutrition (p = 0.047; OR 1.038, CI 1.011–1.066). iscorEB enabled the identification of patients with moderate-to-severe malnutrition with an Area Under Receiver Operating Curve (AUROC) of 0.72 (95%CI 0.58–0.85; p < 0.005). In phase 2, there was significant improvement in nutritional status in children with recessive dystrophic EB (RDEB) and dominant dystrophic EB (DDEB) subtype (p < 0.0001). The severity of malnutrition in EB children significantly correlates with disease severity, and is an independent predictor of moderate-to-severe malnutrition.

scholarly journals Effect of nutritonal therapy on Helicobacter pylori infections in severely malnourished children

2010 ◽  
Vol 50 (5) ◽  
pp. 278
Author(s):  
Mahdin A. Husaini ◽  
Jajah K. Husaini ◽  
Susie Suwarti ◽  
Yekti Widodo Heryudarini Harahap
Keyword(s):  
Nutritional Status ◽  
Nutritional Intervention ◽  
Clinic Visit ◽  
Severe Malnutrition ◽  
Noticeable Effect ◽  
Malnourished Children ◽  
Z Scores ◽  
Parental Counseling ◽  
Skimmed Milk ◽  
H Pylori

Background Severe malnutrition young children has been a problem in Indonesia for many years. In recent years the condition may be increasing. Besides a lack of nutrition, H. pylori infection may contribute to this condition.Objective To determine if severely malnourished children have high rates of H. pylori infection, and to test if improving nutritional deficiency by drinking skimmed milk can reduce the number of H. pylori cases.Methods A total of 83 children aged 6 - 36 months with severe malnutrition (weight-for-age < -3 Z-scores), who were outpatients at the Nutrition Clinic in fugor served as subjects for this longitudinal study. Out of 83 children, 42 subjects (50%) tested positively for H. pylori infection (Group P) and 41 subjects  (49.4%) tested negatively (Group NP). All subjects received the same nutritional intervention consisting  of medical care, 250 g of skimmed milk, and guidance concerning proper feeding and care of children at every clinic visit, for a duration of 6 months.Results The study revealed that after 6 months of nutritional intervention, the percentage of children suffering from diarrhea was significantly (P < 0.05) reduced in Group P, while no significant change was demonstrated in Group NP. The nutritional intervention also demonstrated a noticeable effect on the incidence of H pylori infection, reducing the number of H. pylori infections by 29% in Group P. In Group Np, 100% of the children remained free of H. pylori infection after intervention. No new cases of H. pylori infection appeared in either group. An improvement in nutritional status was also observed: 23.8% of severely undernourished children in Group P and 3 4.1 % in Group NP improved after intervention.Conclusion Drinking skimmed milk twice daily, as well as parental counseling on proper feeding and child care, led to improved nutritional status of severely malnourished children. We also observed that skimmed (non-fat) milk may have a role in preventing and treating malnourished children with H. pylori infection.

scholarly journals Factors related to under nutrition among children in a rural area in Patan district of Gujarat, India

2018 ◽  
Vol 6 (1) ◽  
pp. 142
Author(s):  
Punit Patel ◽  
Shreyashkumar J. Gandhi ◽  
Pushti Vachhani ◽  
Nishant Bhimani
Keyword(s):  
Nutritional Status ◽  
Rural Area ◽  
Gender Discrimination ◽  
Rural Areas ◽  
Maternal Education ◽  
Family Income ◽  
Occupational Status ◽  
Secondary Data ◽  
Severe Malnutrition ◽  
Anthropometric Parameters

Background: Malnutrition is defined as ‘undernutrition’ resulting from inadequate consumption, poor absorption or excessive loss of nutrients and also includes ‘overnutrition’, resulting from excessive intake of specific nutrients. Infant-feeding practices play a major role in child caring practices apart from socio-cultural, demographic and economic factors. The present study was conducted to assess socio-demographic and other factors associated with undernutrition in rural areas of Patan.Methods: This present study was conducted at 6 Anganwadi centers of Kungher rural area of Patan during 2017-2018. Total 293 of 1 to 5 year children were included in the study. Secondary data was collected through study of records and reports from AWW. Mothers of selected children were interviewed for collecting desired information. The children were examined for anthropometric parameters (weight and height) and nutritional status.Results: Out of 293 children 159 (54.2%) subjects were males. Total 190 (64.8%) children were ICDS beneficiaries. More than half of children (55.6%) were undernourished. Severe malnutrition was more distributed among unregistered (54.5%). Two third of illiterate mothers had undernourished children (69.8%). More than half of children (59.9%) belonging to lower socio economic class were undernourished. More than 2/3rd of low birth weight (LBW) children were found to be undernourished.Conclusions: Child’s nutritional status had significantly affected by maternal education and occupational status. Many other key factors such as family income, gender discrimination and LBW are playing an important role in nutritional status children. 

P0952NEUTROPHIL GELATINASE - ASSOCIATED LIPOCALIN LEVEL AS A MARKER OF MALNUTRITION IN HEMODIALYSIS PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Alaa Sabry ◽  
Rasha Mahmoud ◽  
Shimaa Alsaody
Keyword(s):  
Nutritional Status ◽  
Complete Blood Count ◽  
Serum Levels ◽  
Hemodialysis Patients ◽  
Severe Malnutrition ◽  
Roc Curve Analysis ◽  
Anthropometric Parameters ◽  
Dialysis Adequacy ◽  
Good Ability ◽  
Increased Risk

Abstract Background and Aims Among hemodialysis patients, malnutrition is a common health problem, it is a marker of poor prognosis in these patients, associated with increased risk of hospitalization and mortality. NGAL is an iron transporting factor which increases in the serum in acute and chronic kidney disease. The aim of our study is to assess the use of NGAL as a marker of malnutrition in patients with stage 5 CKD maintained on hemodialysis. Method This is a cross-sectional study of 80 regular hemodialysis (HD) patients (51 males and 29 females). All cases of this study were subjected to: Anthropometric measurements . Biochemical measurements: Neutrophil Gelatinase-associated Lipocalin Level in blood using commercially available ELIZA kits, Serum albumin, Blood urea, Complete blood count, Serum electrolytes . Results According to the result we found in our study 100% of CKD having malnutrition according to SGA, MIS and our data however most of our patients are mild malnutrition. We found also a significant decrease in some anthropometric parameters including BMI, fat mass, TSF, MAC, MAMC and MAMA with advanced malnutrition in hemodialysis patients. In this study, we use Twenty-four hours dietary recall and we found most of patients were with low protein (96.2%) and calorie (68.8%) contents. Dialysis adequacy (Kt/V) can affect the nutritional status of patients Kt/V was adequate in all malnutrition groups. These findings are consistent with an earlier report in which HD patients with Kt/V&gt;1.4 had a significantly higher rate of malnutrition than patients with Kt/V ≤1.4. in this study NGAL serum levels were significantly (P=0.018) reduced with the severity of malnutrition. In this study, Spearman correlation analysis revealed that NGAL serum levels were significantly correlated with SGA (r =o,247 P =0.027) and albumin serum levels (r =0.402, P &lt;0.001). NGAL serum levels were significantly (P=0.018) reduced with the severity of malnutrition. Using ROC curve analysis, NGAL serum levels had a good ability (AUC=0.845) to predict severe malnutrition with good sensitivity (83.3%) and specificity (78.4%). Conclusion NGAL is well correlated with other standard markers used routinely in assessment of nutritional status of hemodialysis patients. Patients with high NGAL levels were closely related to good nutritional status. Its serum levels had a good diagnostic power for severe-malnourished patients, as it helps us for early prediction to malnutrition.

scholarly journals Simple methods for nutritional status assessment in patients treated with repeated hemodialysis

2004 ◽  
Vol 57 (9-10) ◽  
pp. 439-444 ◽  
Author(s):  
Biserka Tirmenstajn-Jankovic ◽  
Nada Dimkovic
Keyword(s):  
Nutritional Status ◽  
Body Mass ◽  
Body Fat ◽  
Protein Energy Malnutrition ◽  
Hemodialysis Patients ◽  
Anthropometric Measurements ◽  
Severe Malnutrition ◽  
Dialysis Patients ◽  
Fat Percentage ◽  
Anthropometric Parameters

Introduction Protein-energy malnutrition is common in chronic hemodialysis patients and is strongly associated with increased morbidity and mortality. While determination of the nutritional status is often based on objective measurements such as biochemical parameters and anthropometric measurements, there is no single measurement that can reliably identify risk for malnutrition. Material and methods A subjective global assessment (SGA) was performed to evaluate the nutritional status in 43 chronic dialysis patients (27 men and 16 women). Anthropometric measurements including body weight (BW), body mass index (BMI), skin-fold thickness (triceps-TS, biceps-BS, subscapular-SSS, suprailiac-SIS), mid-arm circumference (MAC); mid-arm muscle circumference (MAMC); body fat percentage (%BF); total body fat (TBF); lean body mass (LBM) and laboratory parameters (total proteins, albumins, transferrin, hemoglobin, lymphocytes. Results According to SGA, patients were divided into three groups: first group of 23 pts with a normal nutritional status, second group of 11 pts with mild malnutrition and third group of 9 pts with moderate or severe malnutrition. In examined groups there was a significant decrease in total protein (p = 0.02), serum albumin (p = 0.000) and hemoglobin (p = 0.04) levels with an increase in SGA scores (oneway ANOVA). In the same way, SGA was correlated with the number of anthropometric parameters (BW, BMI, TS, SSS, SIS, MAC, MAMC, % BF, TBF, LBM). Conclusion Our data confirmed a high prevalence of malnutrition in hemodialysis patients and showed that SGA closely correlated with more objective measures. Being an inexpensive method of well-proven realibility, SGA can be recommended for a more frequent assessment of nutritional status in dialysis patients.

Anthropometric evaluation of school-going native highlanders (4–19 years of age) from the Leh-Ladakh region in India

2019 ◽  
Vol 0 (0) ◽  
Author(s):  
Uday Yanamandra ◽  
Srinivasa A. Bhattachar ◽  
Deeksha Katoch ◽  
Sushma Yanamandra ◽  
Siddharth Shankar ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Reference Data ◽  
World Health ◽  
Abdominal Circumference ◽  
Anthropometric Parameters ◽  
Cross Sectional ◽  
Z Scores ◽  
The Mean ◽  
Health Organization ◽  
Going Native

Abstract Background The native population of the Ladakh region faces the unique challenges of a high-altitude environment with distinct physiological adaptations in comparison with lowlanders. However, no comprehensive data on standard anthropometric parameters for the school-going children in this populace is available. Objectives We aimed to study the various anthropometric parameters in the school-going native highlander population and computed measures of central tendency. The nutritional status of the community was also be determined by comparing with World Health Organization (WHO) scores for height for age (HFA), weight for age (WFA) and body mass index (BMI) for age. Design A cross-sectional, descriptive study was devised to assess the anthropometric parameters. We measured height, weight, mid-upper circumference (MUAC), triceps skinfold (TSF) thickness, sub-scapular skinfold (SSF) thickness, waist, hip and abdominal circumference. Statistical analysis was conducted to determine the mean [±2 standard deviation (SD)], median, range, minimum and maximum. The z-scores for HFA, WFA and BMI for age was computed using WHO reference data. Subjects A total of 346 school-going native highlander children (4–19 years of age) were studied. Results Among the study population, the mean height was 141.17 ± 39.08 cm, the mean weight was 38.27 ± 25.40 kg. The gender difference in height, MUAC, sub-scapular skinfold (SSF) thickness, TSF thickness and the abdominal circumference was found to be statistically significant. Of the subjects 23.46% were stunted (i.e. HFA below −2 SD of the WHO standard) and 7.01% were underweight (WFA below −2 SD of the WHO standard). Conclusion The nutritional status of the Ladakhi population was assessed by comparison with the WHO reference data. Nomograms for anthropometric data in school-going children (4–19 years of age) of Ladakh were created. These can be used for further studies and planning targeted intervention strategies on this geographically isolated and evolutionary distinct highland population.

Evaluation of the nutritional status of Indian children from Alto Xingu, Brazil

2002 ◽  
Vol 78 (5) ◽  
pp. 383-8 ◽  
Author(s):  
Carlos A. G. Oliva ◽  
Ulysses Fagundes Neto ◽  
Ulysses Fagundes
Keyword(s):  
Nutritional Status ◽  
Indian Children

scholarly journals Nutritional status and risk of contrast-associated acute kidney injury in elderly patients undergoing percutaneous coronary intervention

2021 ◽  
Author(s):  
Xiaoqi Wei ◽  
Hanchuan Chen ◽  
Zhebin You ◽  
Jie Yang ◽  
Haoming He ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Percutaneous Coronary Intervention ◽  
Nutritional Status ◽  
Elderly Patients ◽  
Kidney Injury ◽  
Coronary Intervention ◽  
Severe Malnutrition ◽  
Percutaneous Coronary ◽  
Conut Score

Abstract Background This study aimed to investigate the connection between malnutrition evaluated by the Controlling Nutritional Status (CONUT) score and the risk of contrast-associated acute kidney injury (CA-AKI) in elderly patients who underwent percutaneous coronary intervention (PCI). Methods A total of 1308 patients aged over 75 years undergoing PCI was included. Based on the CONUT score, patients were assigned to normal (0–1), mild malnutrition (2–4), moderate-severe malnutrition group (≥ 5). The primary outcome was CA-AKI (an absolute increase in ≥ 0.3 mg/dL or ≥ 50% relative serum creatinine increase 48 h after contrast medium exposure). Results Overall, the incidence of CA-AKI in normal, mild, moderate-severe malnutrition group was 10.8%, 11.0%, and 27.2%, respectively (p < 0.01). Compared with moderate-severe malnutrition group, the normal group and the mild malnutrition group showed significant lower risk of CA-AKI in models adjusting for risk factors for CA-AKI and variables in univariate analysis (odds ratio [OR] = 0.48, 95% confidence interval [CI]: 0.26–0.89, p = 0.02; OR = 0.46, 95%CI: 0.26–0.82, p = 0.009, respectively). Furthermore, the relationship were consistent across the subgroups classified by risk factors for CA-AKI except anemia. The risk of CA-AKI related with CONUT score was stronger in patients with anemia. (overall interaction p by CONUT score = 0.012). Conclusion Moderate-severe malnutrition is associated with higher risk of CA-AKI in elderly patients undergoing PCI.

Dental Caries Severity and Nutritional Status of Nigerian Preschool Children

2021 ◽  
pp. 238008442110021
Author(s):  
O.O. Olatosi ◽  
A.A. Alade ◽  
T. Naicker ◽  
T. Busch ◽  
A. Oyapero ◽  
...  
Keyword(s):  
Early Childhood ◽  
Dental Caries ◽  
Nutritional Status ◽  
Early Childhood Caries ◽  
Z Score ◽  
Cross Sectional ◽  
Risk Of Death ◽  
Malnourished Children ◽  
Z Scores ◽  
Childhood Caries

Introduction: Malnutrition in children is one of the most prevalent global health challenges, and malnourished children have a higher risk of death from childhood diseases. Early childhood caries (ECC) is the most common chronic disease of childhood. Complications from ECC such as pain, loss of tooth/teeth, and infection can undermine a child’s nutrition and growth. Aim: This study aims to evaluate the severity of decay, missing, and filled tooth (dmft) by nutritional status using the z scores of the anthropometric measurements: height for age (HFA), weight for age (WFA), weight for height (WFH), and body mass index for age (BMIA) among children with ECC in Nigeria. Study Design: This is a cross-sectional study conducted in 5 local government areas (LGAs) in Lagos State, Nigeria. A multistage sampling technique was used. Results: A total of 273 cases of ECC were included in the analyses (mean age 4.19 ± 0.96 y). Overall, the mean dmft was 3.04 ± 2.28, and most (96%) were accounted for by untreated decay. The distribution of dmft within the different z score categories of BMIA (<–3 = severely wasted, –2 to –3 = wasted, –2 to +2 = normal, +2 to +3 = overweight and >+3 = obese) showed the highest dmft scores among the combined severely wasted and wasted groups, lowest among children with normal z scores, and intermediate in the overweight and obese groups. There was a significant negative correlation between BMIA z score, WFH z score, and dmft ( r = −0.181, P < 0.05 and r = −0.143, P < 0.05, respectively). However, the correlations between HFA z score, WFA z score, and dmft were positive but not significant ( r = 0.048, P = 0.44 and r = 0.022, P = 0.77, respectively). Conclusion: Our study showed an increased severity of dental caries among severely wasted or wasted children with ECC compared to those of normal or overweight. Knowledge Transfer Statement: The results from this study will raise awareness among clinicians and policy makers on the need for a primary prevention program for early childhood caries in countries with high burden of malnutrition and limited resources. Also, it will help draw the attention of clinicians to the caries status of malnourished children that can be managed to improve the nutritional outcomes.

scholarly journals Functionality of Bread and Beverage Added with Brosimum alicastrum Sw. Seed Flour on the Nutritional and Health Status of the Elderly

Foods ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 1764
Author(s):  
Alejandra Rodríguez-Tadeo ◽  
Julio C del Hierro-Ochoa ◽  
Jesús O. Moreno-Escamilla ◽  
Joaquín Rodrigo-García ◽  
Laura A. de la Rosa ◽  
...  
Keyword(s):  
Nutritional Status ◽  
The Elderly ◽  
Total Phenolic ◽  
Affective States ◽  
Anthropometric Parameters ◽  
Seed Flour ◽  
Control Stage ◽  
Brosimum Alicastrum ◽  
Usual Diet

Physiological changes in elderly individuals (EI) can contribute to nutritional deterioration and comorbidities that reduce their quality of life. Factors such as diet can modulate some of these effects. The aim was to evaluate the functionality of foods added with Brosimum alicastrum Sw. seed flour in EI. EI (n = 23) living in nursing home conditions agreed to participate. A control stage was carried out (30 days) and subsequently, an intervention stage (30 days) was realized in which a muffin and a beverage, designed for EI, were added to the participants’ their usual diet. In both stages, anthropometric parameters, body composition, nutritional status, dietary intake, sarcopenic status, cognitive and affective states, biometric parameters, and total phenolic compounds (TPC), and antioxidant capacity in foods and plasma of EI were determined. The results showed that the consumption of the foods improved the energy intake and preserved the muscle reserves of the EI. The EI gained body weight (+1.1 kg), increased their protein (+18.6 g/day; 1.5 g/kg BW/day), dietary fiber (+13.4 g/day), iron (+4.4 mg/day), zinc (+1.8 mg/day), folic acid (+83.4 µg/day) consumption while reducing their cholesterol (−66 mg/day) and sodium (−319.5 mg/day) consumption. LDL-C lipoproteins reduced (14.8%) and urea (33.1%) and BUN (33.3%) increased. The TPC increased (7.8%) in the plasma, particularly in women (10.7%). The foods improve the EI nutritional status, and this has a cardiovascular protective effect that can benefit the health of the EI.

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