scholarly journals Is obesity really due to high energy intake of low energy expenditure?

1998 ◽  
Vol 22 (11) ◽  
pp. 1139-1140 ◽  
Author(s):  
JCK Wells
1980 ◽  
Vol 28 (4) ◽  
pp. 211-227 ◽  
Author(s):  
L.A. den Hartog ◽  
G.J.M. van Kempen

A review of experiments on the effect of energy and protein intake on fertility in gilts suggested that a high energy intake shortly before oestrus (flushing) increased ovulation rate. Although high energy intake gave more ovulations than low energy intake, embryonic mortality was greater. The most suitable sequence during rearing, flushing and early pregnancy seemed to be low, high and low energy, respectively. (Abstract retrieved from CAB Abstracts by CABI’s permission)


2008 ◽  
Vol 105 (1) ◽  
pp. 58-64 ◽  
Author(s):  
Joseph A. Alemany ◽  
Bradley C. Nindl ◽  
Mark D. Kellogg ◽  
William J. Tharion ◽  
Andrew J. Young ◽  
...  

Energy restriction coupled with high energy expenditure from arduous work is associated with an altered insulin-like growth factor-I (IGF-I) system and androgens that are coincident with losses of fat-free mass. The aim of this study was to determine the effects of two levels of dietary protein content and its effects on IGF-I, androgens, and losses of fat-free mass accompanying energy deficit. We hypothesized that higher dietary protein content would attenuate the decline of anabolic hormones and, thus, prevent losses of fat-free mass. Thirty-four men [24 (SD 0.3) yr, 180.1 (SD 1.1) cm, and 83.0 (SD 1.4) kg] participated in an 8-day military exercise characterized by high energy expenditure (16.5 MJ/day), low energy intake (6.5 MJ/day), and sleep deprivation (4 h/24 h) and were randomly divided into two dietary groups: 0.9 and 0.5 g/kg dietary protein intake. IGF-I system analytes, androgens, and body composition were assessed before and on days 4 and 8 of the intervention. Total, free, and nonternary IGF-I and testosterone declined 50%, 64%, 55%, and 45%, respectively, with similar reductions in both groups. There was, however, a diet × time interaction on day 8 for total IGF-I and sex hormone-binding globulin. Decreases in body mass (3.2 kg), fat-free mass (1.2 kg), fat mass (2.0 kg), and percent body fat (1.5%) were similar in both groups ( P = 0.01). Dietary protein content of 0.5 and 0.9 g/kg minimally attenuated the decline of IGF-I, the androgenic system, and fat-free mass during 8 days of negative energy balance associated with high energy expenditure and low energy intake.


2015 ◽  
pp. S395-S402 ◽  
Author(s):  
R. POLEDNE ◽  
I. KRÁLOVÁ LESNÁ ◽  
S. ČEJKOVÁ

High-energy intake which exceeds energy expenditure leads to the accumulation of triglycerides in adipose tissue, predominantly in large-size adipocytes. This metabolic shift, which drives the liver to produce atherogenic dyslipidemia, is well documented. In addition, an increasing amount of monocytes/macrophages, predominantly the proinflammatory M1-type, cumulates in ectopic adipose tissue. The mechanism of this process, the turnover of macrophages in adipose tissue and their direct atherogenic effects all remain to be analyzed.


Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1168 ◽  
Author(s):  
Hye Kang ◽  
Sang Lee ◽  
Dammah Otieno ◽  
Kyoungsoo Ha

Obesity results from the body having either high energy intake or low energy expenditure. Based on this energy equation, scientists have focused on increasing energy expenditure to prevent abnormal fat accumulation. Activating the human thermogenic system that regulates body temperature, particularly non-shivering thermogenesis in either brown or white adipose tissue, has been suggested as a promising solution to increase energy expenditure. Together with the increasing interest in understanding the mechanism by which plant-derived dietary compounds prevent obesity, flavonoids were recently shown to have the potential to regulate non-shivering thermogenesis. In this article, we review the latest research on flavonoid derivatives that increase energy expenditure through non-shivering thermogenesis.


1985 ◽  
Vol 33 (1) ◽  
pp. 23-34
Author(s):  
G.J.M. van Kempen ◽  
C. Geerse ◽  
M.W.A. Verstegen ◽  
J. Mesu

During 2nd lactation, 12 Dutch Landrace X Norwegian Landrace sows suckling 7-9 piglets were kept in farrowing crates in calorimeters and given a 21.4% protein diet at 2.5 kg (ME about 800 kJ/kg0.75) or 4.8-6 kg (ME about 1500 kJ/kg0.75) daily. The diet was reckoned to supply requirements for milk production at the higher intake but not at the lower intake. Weight loss in days 4-25 of lactation averaged 10 and 28 kg for sows with high and low energy intakes, resp. From day 10 onwards, sows on the low energy intake gave less milk but with higher concn. of total solids, fat and protein than sows on the high intake. Yields of energy and protein were significantly higher in sows on high intakes only after day 15 of lactation. The daily gain of piglets was lower with the low energy intake; daily milk intake by piglets was higher, but energy intake per kg piglet gain was lower, with the high energy intake. Age of piglets had a significant effect on milk needed for gain. (Abstract retrieved from CAB Abstracts by CABI’s permission)


Author(s):  
Sadia Fatima ◽  
Konstantinos Gerasimidis ◽  
Charlotte Wright ◽  
Dalia Malkova

Abstract Background/Objective Morning consumption of a single dose of high-energy oral nutritional supplement (ONS) in females with a lower BMI displaces some of the food eaten at breakfast but increases overall daily energy intake. This study investigated the effectiveness of ONS intake in the late afternoon and for longer duration. Subjects/Methods Twenty-one healthy females (mean ± SD, age 25 ± 5 years; BMI 18.7 ± 1.2 kg/m2) participated in a randomised, crossover study with two experimental trials. In the afternoon of days 1–5, participants consumed either ONS (2.510 MJ) or low-energy PLACEBO drink (0.377 MJ) and recorded food eaten at home. On day six, energy intake was measured during buffet meals, and energy expenditure, appetite measurements and blood samples were collected throughout the day. Result Over the 5-day period, in the ONS trial energy intake from evening meals was lower (ONS, 2.7 ± 0.25 MJ; Placebo, 3.6 ± 0.25 MJ, P = 0.01) but averaged total daily energy intake was higher (ONS, 9.2 ± 0.3 MJ; PLACEBO, 8.2 ± 0.4 MJ, P = 0.03). On day six, energy intake, appetite scores, plasma GLP-1 and PYY, and energy expenditure were not significantly different between the two trials but fasting insulin concentration and HOMAIR, were higher (P < 0.05) and insulin sensitivity score based on fasting insulin and TAG lower (P < 0.05) in ONS trial. Conclusion Late afternoon consumption of ONS for five consecutive days by females with a lower BMI has only a partial and short-lived energy intake suppression and thus increases daily energy intake but reduces insulin sensitivity.


1967 ◽  
Vol 21 (4) ◽  
pp. 879-891 ◽  
Author(s):  
J. J. Robinson ◽  
T. J. Forbes

1. An experiment was carried out in which protein utilization in the pregnant ewe was studied using the nitrogen balance technique.2. Eight diets supplying four different intakes of crude protein and two different intakes of energy were each offered to eight individually penned ewes.3. The mean crude protein intakes per day were 7·2, 5·5, 4·1 and 3·0 g/kg W0·73 (where W = body-weight) and the metabolizable energy intakes 134 and 113 kcal/kg W0·73.4. N balances were carried out at 10–12, 14–16 and 18–20 weeks of gestation on five ewes from each treatment.5. The apparent digestibility of both dry matter and crude protein decreased with decreasing protein intake. With the high energy intake, the apparent dry-matter digestibility was increased and the apparent digestibility of crude protein decreased. Stage of gestation had no significant effect on the apparent digestibility of either of these constituents.6. N retention was not affected by the number of foetuses carried. With the higher energy intake and the higher protein intakes, the absolute retention of N was significantly increased at all stages of gestation. N retention increased with advancing pregnancy; the retentions at 10–12, 14–16 and 18–20 weeks of gestation being 0·086, 0·114 and 0·163 g/kg W0·73 per day respectively.7. The efficiency of utilization of apparently digested N was calculated from the regression of retained N as a percentage of apparently digested N against apparently digested N.8. The daily intakes of apparently digested N required for maximum efficiency were 0·551 and 0·620 g/kg W0·73 on the high and low energy intakes respectively. The daily intake for maximum efficiency decreased with advancing pregnancy, the values being 0·623, 0·587 and 0·567 g/kg W0·73 for the 10–12, 14–16 and 18–20 weeks of gestation respectively.9. The levels of N retained at maximum efficiency were 0·235 and 0·202 g/kg W0·73 per day for the high and low energy intakes respectively. The levels of N retained increased during pregnancy from 0·170 g/kg W0·73 per day at 10–12 weeks to 0·286 g/kg W0·73 at 18–20 weeks. The requirements for zero N balance were 0·072 and 0·153 g apparently digested N/kg W0·73 per day for the high and low energy intakes respectively. The requirement for zero N balance decreased from 0·176 g/kg W0·73 per day at 10–12 weeks to 0·071 g/kg W0·73 at 18–20 weeks.10. The results are discussed in relation to other research findings and current recommendations.


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