Modification of the kinetic parameters of aldolase on binding to the actin-containing filaments of skeletal muscle
Keyword(s):
The kinetic parameters of fructose bisphosphate aldolase (EC 4.1.2.13) were shown to be modified on binding of the enzyme to the actin-containing filaments of skeletal muscle. Although binding to F-actin or F-actin-tropomyosin filaments results in relative minor changes in kinetic properties, binding to F-actin-tropomyosin-troponin filaments produces major alterations in the kinetic parameters, and, in addition, renders them Ca2+-sensitive. These observations may be relevant to an understanding of the function of this enzyme within the muscle fibre.
1991 ◽
Vol 47
(1)
◽
pp. 1-9
◽
1978 ◽
Vol 253
(5)
◽
pp. 1451-1457
◽
Keyword(s):
Keyword(s):
2018 ◽
Vol 12
◽
pp. 117793221880970
◽
Keyword(s):