scholarly journals Yebes 40 m radio telescope and the broad band Nanocosmos receivers at 7 mm and 3 mm for line surveys

2021 ◽  
Vol 645 ◽  
pp. A37
Author(s):  
F. Tercero ◽  
J. A. López-Pérez ◽  
J. D. Gallego ◽  
F. Beltrán ◽  
O. García ◽  
...  
Keyword(s):  
Radio Telescope ◽  
Signal To Noise Ratio ◽  
Broad Band ◽  
High Sensitivity ◽  
Lower Sensitivity ◽  
Molecular Chemistry ◽  
Long Baseline ◽  
New Instrumentation ◽  
Frequency Coverage ◽  
Technical Specifications

Context. Yebes 40 m radio telescope is the main and largest observing instrument at Yebes Observatory and is devoted to very long baseline interferometry (VLBI) and single-dish observations since 2010. It has been covering frequency bands between 2 GHz and 90 GHz in discontinuous and narrow windows in most cases in order to match the current needs of the European VLBI Network (EVN) and the Global Millimeter VLBI Array (GMVA). Aims. The Nanocosmos project, a European Union-funded synergy grant, has enabled an increase in the instantaneous frequency coverage of the Yebes 40 m radio telescope, making it possible to observe many molecular transitions with single tunings in single-dish mode. This reduces the observing time and maximises the output from the telescope. Methods. We present technical specifications of the recently installed 31.5−50 GHz (Q band) and 72−90.5 GHz (W band) receivers along with the main characteristics of the telescope at these frequency ranges. We observed IRC+10216, CRL 2688, and CRL 618, which harbour a rich molecular chemistry, to demonstrate the capabilities of the new instrumentation for spectral observations in single-dish mode. Results. Our results show the high sensitivity of the telescope in the Q band. The spectrum of IRC+10126 offers an unprecedented signal-to-noise ratio for this source in this band. On the other hand, the spectrum normalised by the continuum flux towards CRL 618 in the W band demonstrates that the 40 m radio telescope produces comparable results to those from the IRAM 30 m radio telescope, although with a lower sensitivity. The new receivers fulfil one of the main goals of Nanocosmos and open up the possibility to study the spectrum of different astrophysical media with unprecedented sensitivity.

Portable Laser Spectrofluorimeter System for in Vivo Human Tissue Fluorescence Studies

1993 ◽  
Vol 47 (12) ◽  
pp. 2081-2086 ◽  
Author(s):  
James F. Brennan ◽  
George I. Zonios ◽  
Thomas D. Wang ◽  
Richard P. Rava ◽  
Gary B. Hayes ◽  
...  
Keyword(s):  
Human Tissue ◽  
Signal To Noise Ratio ◽  
Broad Band ◽  
High Sensitivity ◽  
Single Pulse ◽  
Fiber Optic Probe ◽  
Human Artery ◽  
Fluorescence Studies ◽  
Optic Probe

A compact, portable spectrofluorimeter which measures broad-band fluorophores with high sensitivity is described. This instrument is specifically designed for acquisition of human tissue autofluorescence spectra in vivo. Pulsed excitation laser light at 337 nm and in the 370–700 nm wavelength range is provided, and the resulting fluorescence can be measured with 10-nm resolution. The system produces single-pulse spectra in human artery wall tissues with a signal-to-noise ratio of 100:1. An optically shielded fiber-optic probe for light delivery and collection permits calibrated intensity information to be obtained.

Measurements of radio telescope receiving system noise temperatures of two-elements radio interferometer with very long baseline

2018 ◽  
pp. 51-54
Author(s):  
I. E. Arsaev ◽  
Yu. V. Vekshin ◽  
A. I. Lapshin ◽  
V. V. Mardyshkin ◽  
M. V. Sargsyan ◽  
...  
Keyword(s):  
Radio Telescope ◽  
Radio Interferometer ◽  
System Noise ◽  
Long Baseline

scholarly journals The Double Face of Ketamine—The Possibility of Its Identification in Blood and Beverages

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 813
Author(s):  
Magdalena Świądro ◽  
Paweł Stelmaszczyk ◽  
Irena Lenart ◽  
Renata Wietecha-Posłuszny
Keyword(s):  
Date Rape ◽  
Signal To Noise Ratio ◽  
High Sensitivity ◽  
Heroin Addiction ◽  
Assisted Extraction ◽  
Low Concentrations ◽  
High Concentrations ◽  
Rosé Wine ◽  
Tof Ms

The purpose of this study was to develop and validate a high-sensitivity methodology for identifying one of the most used drugs—ketamine. Ketamine is used medicinally to treat depression, alcoholism, and heroin addiction. Moreover, ketamine is the main ingredient used in so-called “date-rape” pills (DRP). This study presents a novel methodology for the simultaneous determination of ketamine based on the Dried Blood Spot (DBS) method, in combination with capillary electrophoresis coupled with a mass spectrometer (CE-TOF-MS). Then, 6-mm circles were punched out from DBS collected on Whatman DMPK-C paper and extracted using microwave-assisted extraction (MAE). The assay was linear in the range of 25–300 ng/mL. Values of limits of detection (LOD = 6.0 ng/mL) and quantification (LOQ = 19.8 ng/mL) were determined based on the signal to noise ratio. Intra-day precision at each determined concentration level was in the range of 6.1–11.1%, and inter-day between 7.9–13.1%. The obtained precision was under 15.0% (for medium and high concentrations) and lower than 20.0% (for low concentrations), which are in accordance with acceptance criteria. Therefore, the DBS/MAE/CE-TOF-MS method was successfully checked for analysis of ketamine in matrices other than blood, i.e., rose wine and orange juice. Moreover, it is possible to identify ketamine in the presence of flunitrazepam, which is the other most popular ingredient used in DRP. Based on this information, the selectivity of the proposed methodology for identifying ketamine in the presence of other components of rape pills was checked.

scholarly journals Mid-infrared photoacoustic gas monitoring driven by a gas-filled hollow-core fiber laser

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yazhou Wang ◽  
Yuyang Feng ◽  
Abubakar I. Adamu ◽  
Manoj K. Dasa ◽  
J. E. Antonio-Lopez ◽  
...  
Keyword(s):  
Fiber Laser ◽  
Signal To Noise Ratio ◽  
High Sensitivity ◽  
Laser Source ◽  
High Signal ◽  
Mid Infrared ◽  
Raman Fiber Laser ◽  
Custom Made ◽  
Core Fiber ◽  
Detection Technologies

AbstractDevelopment of novel mid-infrared (MIR) lasers could ultimately boost emerging detection technologies towards innovative spectroscopic and imaging solutions. Photoacoustic (PA) modality has been heralded for years as one of the most powerful detection tools enabling high signal-to-noise ratio analysis. Here, we demonstrate a novel, compact and sensitive MIR-PA system for carbon dioxide (CO2) monitoring at its strongest absorption band by combining a gas-filled fiber laser and PA technology. Specifically, the PA signals were excited by a custom-made hydrogen (H2) based MIR Raman fiber laser source with a pulse energy of ⁓ 18 μJ, quantum efficiency of ⁓ 80% and peak power of ⁓ 3.9 kW. A CO2 detection limit of 605 ppbv was attained from the Allan deviation. This work constitutes an alternative method for advanced high-sensitivity gas detection.

scholarly journals 60–700 K CTAT and PTAT Temperature Sensors with 4H-SiC Schottky Diodes

Sensors ◽  
2021 ◽  
Vol 21 (3) ◽  
pp. 942
Author(s):  
Razvan Pascu ◽  
Gheorghe Pristavu ◽  
Gheorghe Brezeanu ◽  
Florin Draghici ◽  
Philippe Godignon ◽  
...  
Keyword(s):  
Low Cost ◽  
Schottky Diodes ◽  
Schottky Contact ◽  
High Sensitivity ◽  
Xrd Analysis ◽  
Absolute Temperature ◽  
Lower Sensitivity ◽  
Readout Circuit ◽  
Sensing Element ◽  
High Performing

A SiC Schottky dual-diode temperature-sensing element, suitable for both complementary variation of VF with absolute temperature (CTAT) and differential proportional to absolute temperature (PTAT) sensors, is demonstrated over 60–700 K, currently the widest range reported. The structure’s layout places the two identical diodes in close, symmetrical proximity. A stable and high-barrier Schottky contact based on Ni, annealed at 750 °C, is used. XRD analysis evinced the even distribution of Ni2Si over the entire Schottky contact area. Forward measurements in the 60–700 K range indicate nearly identical characteristics for the dual-diodes, with only minor inhomogeneity. Our parallel diode (p-diode) model is used to parameterize experimental curves and evaluate sensing performances over this far-reaching domain. High sensitivity, upwards of 2.32 mV/K, is obtained, with satisfactory linearity (R2 reaching 99.80%) for the CTAT sensor, even down to 60 K. The PTAT differential version boasts increased linearity, up to 99.95%. The lower sensitivity is, in this case, compensated by using a high-performing, low-cost readout circuit, leading to a peak 14.91 mV/K, without influencing linearity.

scholarly journals Assessing the usefulness of acute physiological responses following resistance exercise: sensitivity, magnitude of change, and time course of measures

2019 ◽  
Vol 44 (3) ◽  
pp. 309-319 ◽  
Author(s):  
Joshua S. Jackman ◽  
Phillip G. Bell ◽  
Simone Gill ◽  
Ken van Someren ◽  
Gareth W. Davison ◽  
...  
Keyword(s):  
Resistance Exercise ◽  
Time Course ◽  
Signal To Noise Ratio ◽  
Physiological Responses ◽  
High Sensitivity ◽  
Maximal Voluntary Isometric Contraction ◽  
Reactive Protein ◽  
Adaptation Processes ◽  
Exercise Stimulus ◽  
Metalloproteinase 9

A variety of strategies exist to modulate the acute physiological responses following resistance exercise aimed at enhancing recovery and/or adaptation processes. To assess the true impact of these strategies, it is important to know the ability of different measures to detect meaningful change. We investigated the sensitivity of measures used to quantify acute physiological responses to resistance exercise and constructed a physiological profile to characterise the magnitude of change and the time course of these responses. Eight males accustomed to regular resistance exercise performed experimental sessions during a “control week”, void of an exercise stimulus. The following week, termed the “exercise week”, participants repeated this sequence of experimental sessions, and they also performed a bout of lower-limb resistance exercise following the baseline assessments. Assessments were conducted at baseline and at 2, 6, 24, 48, 72, and 96 h after the intervention. On the basis of the signal-to-noise ratio, the most sensitive measures were maximal voluntary isometric contraction, 20-m sprint, countermovement jump peak force, rate of force development (100–200 ms), muscle soreness, Daily Analysis Of Life Demands For Athletes part B, limb girth, matrix metalloproteinase-9, interleukin-6, creatine kinase, and high-sensitivity C-reactive protein with ratios >1.5. Clear changes in these measures following resistance exercise were determined via magnitude-based inferences. These findings highlight measures that can detect real changes in acute physiological responses following resistance exercise in trained individuals. Researchers investigating strategies to manipulate acute physiological responses for recovery and/or adaptation can use these measures, as well as the recommended sampling points, to be confident that their interventions are making a worthwhile impact.

TOWARDS SENSING SINGLE OR A FEW BIO-MOLECULAR ARCHITECTURES: DESIGN OF FUNCTIONAL SURFACES

2008 ◽  
Vol 18 (01) ◽  
pp. 187-194
Author(s):  
PEIJI ZHAO ◽  
DWIGHT WOOLARD ◽  
JORGE M. SEMINARIO ◽  
ROBERT TREW
Keyword(s):  
Density Functional ◽  
High Sensitivity ◽  
Lower Sensitivity ◽  
Label Free ◽  
Dna Molecules ◽  
Surface Attachment ◽  
Biomolecular Sensing ◽  
Aromatic Molecules ◽  
Electrical Sensing ◽  
Silicon Based

There is considerable interest in electrical sensing of biomolecular binding since it has the potential to be label free, to work easily in aqueous environments native to the biomolecules, and to be integrated with small, fast, and inexpensive microelectronoics as detection instrumentation. Although electrochemical methods have been used successfully in detections of DNA molecules with Ag labels at very high sensitivity (~ p ml), detection of DNA molecules in terms of label free techniques has a lower sensitivity (~ μ ml). Here, the surface attachment chemistry is critical towards the detection of ultra-low concentration of biomolecules. In this article, based on density functional theory, we have calculated and analyzed the electrical characteristics of the contact between aromatic molecules and silicon (100) − 2×1 surfaces. Design principles for silicon based electrodes of electrochemically biomolecular sensing instruments for label-free sensing of single or a few biomolecular molecules have also been discussed.

Design of a multi-function high-speed digital baseband data acquisition system

2021 ◽  
Vol 21 (10) ◽  
pp. 248
Author(s):  
Xin Pei ◽  
Jian Li ◽  
Na Wang ◽  
Toktonur Ergesh ◽  
Xue-Feng Duan ◽  
...  
Keyword(s):  
Data Acquisition ◽  
Radio Telescope ◽  
High Speed ◽  
Single Channel ◽  
Wide Band ◽  
Data Acquisition System ◽  
Acquisition System ◽  
Single Server ◽  
Long Baseline ◽  
Digital Baseband

Abstract A multi-function digital baseband data acquisition system is designed for the sampling, distribution and recording of wide-band multi-channel astronomical signals. The system hires a SNAP2 board as a digital baseband converter to digitize, channelize and packetize the received signal. It can be configured dynamically from a single channel to eight channels with a maximum bandwidth of 4096 MHz. Eight parallel HASHPIPE instances run on four servers, each carrying two NVMe SSD cards, achieving a total continuous write rate of 8 GB s−1. Data are recorded in the standard VDIF file format. The system is deployed on a 25-meter radio telescope to verify its functionality based on pulsar observations. Our results indicate that during the 30-minute observation period, the system achieved zero data loss at a data recording rate of 1 GB s−1 on a single server. The system will serve as a verification platform for testing the functions of the QTT (QiTai radio Telescope) digital backend system. In addition, it can be used as a baseband/VLBI (Very Long Baseline Interferometry) recorder or D-F-engine of correlator/beamformer as well.

Low-frequency multiplex CARS microscopy with a high-repetition near-infrared supercontinuum laser

2021 ◽  
Author(s):  
Yusuke Arashida ◽  
Atsushi Taninaka ◽  
Takayuki Ochiai ◽  
Hiroyuki Mogi ◽  
Shoji YOSHIDA ◽  
...  
Keyword(s):  
Near Infrared ◽  
High Efficiency ◽  
Signal To Noise Ratio ◽  
Low Frequency ◽  
High Sensitivity ◽  
High Repetition ◽  
Spectrum Shaping ◽  
Crystal Phase Transition ◽  
Wavenumber Region ◽  
Anti Stokes

Abstract We have developed a multiplex Coherent anti-Stokes Raman scattering (CARS) microscope effective for low-wavenumber measurement by combining a high-repetition supercontinuum light source of 1064 nm and an infrared high-sensitivity InGaAs diode array. This system could observe the low-wavenumber region down to 55 cm-1 with high sensitivity. In addition, using spectrum shaping and spectrum modulation techniques, we simultaneously realized a wide bandwidth (<1800 cm-1), high wavenumber resolution (9 cm-1), high efficiency, and increasing signal to noise ratio by reducing the effect of the background shape in low-wavenumber region. Spatial variation of a sulfur crystal phase transition with metastable states was visualized.

scholarly journals VLBA+GBT observations of the COSMOS field and radio source counts at 1.4 GHz

2018 ◽  
Vol 616 ◽  
pp. A128 ◽  
Author(s):  
N. Herrera Ruiz ◽  
E. Middelberg ◽  
A. Deller ◽  
V. Smolčić ◽  
R. P. Norris ◽  
...  
Keyword(s):  
Radio Source ◽  
Flux Density ◽  
Lower Limit ◽  
High Sensitivity ◽  
Host Galaxy ◽  
Radio Sources ◽  
Source Population ◽  
Star Forming ◽  
Brightness Temperatures ◽  
Long Baseline

We present very long baseline interferometry (VLBI) observations of 179 radio sources in the COSMOS field with extremely high sensitivity using the Green Bank Telescope (GBT) together with the Very Long Baseline Array (VLBA) (VLBA+GBT) at 1.4 GHz, to explore the faint radio population in the flux density regime of tens of μJy. Here, the identification of active galactic nuclei (AGN) is based on the VLBI detection of the source, meaning that it is independent of X-ray or infrared properties. The milli-arcsecond resolution provided by the VLBI technique implies that the detected sources must be compact and have large brightness temperatures, and therefore they are most likely AGN (when the host galaxy is located at z ≥ 0.1). On the other hand, this technique only allows us to positively identify when a radio-active AGN is present, in other words, we cannot affirm that there is no AGN when the source is not detected. For this reason, the number of identified AGN using VLBI should be always treated as a lower limit. We present a catalogue containing the 35 radio sources detected with the VLBA+GBT, ten of which were not previously detected using only the VLBA. We have constructed the radio source counts at 1.4 GHz using the samples of the VLBA and VLBA+GBT detected sources of the COSMOS field to determine a lower limit for the AGN contribution to the faint radio source population. We found an AGN contribution of >40−75% at flux density levels between 150 μJy and 1 mJy. This flux density range is characterised by the upturn of the Euclidean-normalised radio source counts, which implies a contribution of a new population. This result supports the idea that the sub-mJy radio population is composed of a significant fraction of radio-emitting AGN, rather than solely by star-forming galaxies, in agreement with previous studies.

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