Correlation Between Resistin Level and Metabolic Syndrome Component: A Review

2018 ◽  
Vol 50 (07) ◽  
pp. 521-536 ◽  
Author(s):  
Mostafa Mostafazadeh ◽  
Sanya Haiaty ◽  
Ali Rastqar ◽  
Mahtab Keshvari

AbstractMetabolic syndrome (MetS) has a collection of some abnormal and pathological conditions that cause many critical diseases. Resistin is one of the possible candidates for these pathologies but there are not enough data to prove if resistin has positive, neutral, or negative effects on one or some components of MetS. This review summarizes data about comparing the effects and contribution of resistin in initiation and progression of MetS components and also its different actions between human and other mammalians. This summarized data about the relationship of resistin and MetS components have been obtained from clinical researches and in some cases even animal studies. To find the relevant studies, the search in PubMed, Science Direct, and Scopus were performed. Human and animal studies on relationships between resistin and MetS (initiation and progression of components) were included in our search. In experiments reported among different human genetic groups as well as the patients with various disease such as diabetes, no significant correlation is shown between FBG and resistin level. Furthermore, this review shows that the results of correlation between resistin and TG, HDL, and central or abdominal obesity were inconsistent. These inconsistencies can arise from different sample size or genetic groups, gender, and also from experimental studies. Therefore, to obtain precise results systematic review and meta-analyses are required.

2020 ◽  
Vol 7 ◽  
Author(s):  
Anne-Kathrin Burmeister ◽  
Katrin Drasch ◽  
Monika Rinder ◽  
Sebastian Prechsl ◽  
Andrea Peschel ◽  
...  

Only a few birds besides domestic pigeons and poultry can be described as domesticated. Therefore, keeping a pet bird can be challenging, and the human-avian relationship will have a major influence on the quality of this cohabitation. Studies that focus on characterizing the owner-bird relationship generally use adapted cat/dog scales which may not identify its specific features. Following a sociological approach, a concept of human-animal relationship was developed leading to three types of human-animal relationship (impersonal, personal, and close personal). This concept was used to develop a 21-item owner-bird-relationship scale (OBRS). This scale was applied to measure the relationship between pet bird owners (or keepers) (n = 1,444) and their birds in an online survey performed in Germany. Factor analysis revealed that the relationship between owner and bird consisted of four dimensions: the tendency of the owner to anthropomorphize the bird; the social support the bird provides for the owner; the empathy, attentiveness, and respect of the owner toward the bird; and the relationship of the bird toward the owner. More than one quarter of the German bird owners of this sample showed an impersonal, half a personal, and less than a quarter a close personal relationship to their bird. The relationship varied with the socio-demographic characteristics of the owners, such as gender, marital status, and education. This scale supports more comprehensive quantitative research into the human-bird relationship in the broad field of human-animal studies including the psychology and sociology of animals as well as animal welfare and veterinary medicine.


2013 ◽  
Vol 168 (3) ◽  
pp. 393-401 ◽  
Author(s):  
Christa C van Bunderen ◽  
Mirjam M Oosterwerff ◽  
Natasja M van Schoor ◽  
Dorly J H Deeg ◽  
Paul Lips ◽  
...  

ObjectiveHigh as well as low levels of IGF1 have been associated with cardiovascular diseases (CVD). The relationship of IGF1 with (components of) the metabolic syndrome could help to clarify this controversy. The aims of this study were: i) to investigate the association of IGF1 concentration with prevalent (components of) the metabolic syndrome; and ii) to examine the role of (components of) the metabolic syndrome in the relationship between IGF1 and incident CVD during 11 years of follow-up.MethodsData were used from the Longitudinal Aging Study Amsterdam, a cohort study in a representative sample of the Dutch older population (≥65 years). Data were available in 1258 subjects. Metabolic syndrome was determined using the definition of the US National Cholesterol Education Program Adult Treatment Panel III. CVD were ascertained by self-reports and mortality data.ResultsLevels of IGF1 in the fourth quintile were associated with prevalent metabolic syndrome compared with the lowest quintile (odds ratio: 1.59, 95% confidence interval (CI) 1.09–2.33). The middle up to the highest quintile of IGF1 was positively associated with high triglycerides in women. Metabolic syndrome was not a mediator in the U-shaped relationship of IGF1 with CVD. Both subjects without the metabolic syndrome and low IGF1 levels (hazard ratio (HR) 1.75, 95% CI 1.12–2.71) and subjects with the metabolic syndrome and high IGF1 levels (HR 2.28, 95% CI 1.21–4.28) demonstrated increased risks of CVD.ConclusionsIn older people, high-normal IGF1 levels are associated with prevalent metabolic syndrome and high triglycerides. Furthermore, this study suggests the presence of different pathomechanisms for both low and high IGF1 levels and incident CVD.


2014 ◽  
Vol 205 (5) ◽  
pp. 340-347 ◽  
Author(s):  
Christian Loret De Mola ◽  
Giovanny Vinícius Araújo De França ◽  
Luciana de Avila Quevedo ◽  
Bernardo Lessa Horta

BackgroundThere is no consensus on the effects that low birth weight, premature birth and intrauterine growth have on later depression.AimsTo review systematically the evidence on the relationship of low birth weight, smallness for gestational age (SGA) and premature birth with adult depression.MethodWe searched the literature for original studies assessing the effect of low birth weight, premature birth and SGA on adult depression. Separate meta-analyses were carried out for each exposure using random and fixed effects models. We evaluated the contribution of methodological covariates to heterogeneity using meta-regression.ResultsWe identified 14 studies evaluating low birth weight, 9 premature birth and 4 SGA. Low birth weight increased the odds of depression (OR = 1.39, 95% CI 1.21–1.60). Premature birth and SGA were not associated with depression, but publication bias might have underestimated the effect of the former and only four studies evaluated SGA.ConclusionsLow birth weight was associated with depression. Future studies evaluating premature birth and SGA are needed.


2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Bingyang Liu ◽  
Yue Li ◽  
Jiamei Guo ◽  
Yuting Fan ◽  
Ling Li ◽  
...  

Aims. To investigate the influence of body mass index (BMI) and its change from adolescence to adulthood (ΔBMI) on the risk of metabolic syndrome (MetS) in early adulthood. Methods. We selected 931 students from 12 to 16 years of age in Liaoyang City, China. Ninety-three participants from 18 to 22 years of age with complete baseline data were available for follow-up after 5 years. Statistical analysis determined the relationship of MetS at follow-up with baseline BMI (BMIb), ΔBMI, and follow-up BMI (BMIf). Results. ΔBMI was positively correlated with the change of waist circumference (ΔWC), systolic blood pressure (ΔSBP), triglycerides (ΔTG), uric acid, and glycosylated hemoglobin (ΔHbA1c) in follow-up ( p < 0.05 ). For every 1 kg/m2 increase in BMIb, ΔBMI, and BMIf, the risk of MetS at follow-up increased 1.201-fold, 1.406-fold, and 1.579-fold, respectively. Both BMIb and ΔBMI were predictive of MetS at follow-up, with prediction thresholds of 23.47 kg/m2 and 1.95 kg/m2. The participants were divided by the predicted BMIb and ΔBMI threshold values into four study groups. Interestingly, the group with lower BMI but a higher increase in BMI presented the same metabolic derangements and Mets% of the group with higher BMI but lower Δ BMI. Conclusion. Both BMI of adolescence and ΔBMI were predictive of MetS and cardiovascular risk factors in adulthood. Control of both variables in adolescents would be more effective in decreasing the risk of MetS in young adults than control of BMI alone.


2021 ◽  
Vol 1022 ◽  
pp. 181-193
Author(s):  
Dmitry M. Rozhkov ◽  
Evgenia V. Eltoshkina ◽  
Petr I. Ilyin ◽  
Olga A. Svirbutovich

The article presents the results of experimental studies to determine the relationship between the electrolysis modes and the properties of electroplating coatings for mathematical modeling of the dynamics of the electrolytic process (MDEP), described by a system of ordinary differential equations due to the complex relationship of the kinetics of chemical reactions, hydrodynamics and mass transfer in the electrolyte flow, the kinematics of electrode plates, and the influence of the electric field of the "anode-cathode" pair on all these processes. At the same time, the experimental base was a series of full-scale experiments to restore the seats of the root supports of cylinder blocks with electroplated coatings. The final result of the research is the procedure for constructing an optimal resource-saving mode of electroplating, which is a zinc-iron alloy.


Author(s):  
David L. Streiner ◽  
Geoffrey R. Norman ◽  
John Cairney

Although the goal of many clinical assessments and research studies is to measure how much people change between two occasions, the measurement of change is fraught with conceptual and methodological difficulties. One of the difficulties is that there are (at least) two different reasons to measure change: to determine if intervention had any effect, and to identify the correlates of change. These two goals work against each other, because the former requires there to be little difference in the amount of change among people in the same group, while the latter depends on inter-individual differences. The chapter also discusses various biases that exist when people are asked directly how much they think they have changed. This chapter addresses the issues of the relationship of change to the reliability of the scale, difficulties of measuring change in experimental and quasi-experimental studies, and new approaches to measuring change, such as growth curve analysis.


2020 ◽  
Vol 164 ◽  
pp. 14004
Author(s):  
Alexandr Dykha ◽  
Volodymyr Kukhar ◽  
Viktor Artiukh ◽  
Maxim Aleksandrovskiy

Research was conducted to determine the effect of lubricants on stress and strain in the contact of metal surfaces. Experiments were carried out on the introduction of a fixed and moving indenter in contact with a dry and lubricated surface.The steel spherical specimen was pressed into a lubricated and dry metal surface. The microstructures of the structure of the surface layer are studied under various conditions of deformation. The diagrams of the relative deformation of the surface layers are constructed. The mechanism of the formation and distribution of internal stresses for dry and greased contact is described. Experimental studies of the introduction of a moving steel indenter into a lubricated surface have been carried out. The relationship of the deformation mechanisms of lubricated surfaces with their wear resistance is determined. The results obtained are recommended for predicting the durability of lubricated friction units according to the criterion of contact strength.


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