Obesity Is Not A Risk Factor In Thrombophlebitis

1981 ◽  
Author(s):  
M D Kerstein ◽  
R C O’Connell ◽  
N E McSwain

It is alleged that obesity is a risk factor in the occurrence of thrombophlebitis. It is the purpose of this investigation to study that inter-relationship.One hundred consecutive patients (21 male, 79 female) with an average age of 34 years were the subjects for this study. All patients were candidates for surgical intervention (gastric bypass procedure) because of obesity with minimum of 100 lbs over predicted weight. The mean weight was 279.2 lbs with a range of 191 - 500 lbs. The mean body mass index was 48 (weight kg/ (height cm)2). The incidence of deep vein thrombophlebitis by history was 3/100. The history of documented thromboembolism was zero.The incidence of post-operative clinical deep vein thrombophlebitis was zero. The incidence of postoperative thromboembolism was 3/100 (3.0%). None of these patients had a history of deep vein thrombophlebitis. The diagnosis of thromboembolism was confirmed by ventilation-perfusion scan. The mortality rate secondary to thromboembolism was 1/100 (1.0%).Obesity is not a risk factor in the occurrence of postoperative deep vein thrombophlebitis and thromboembolism. The various prophylactic medications and therapies for this group of patients may be an inappropriate risk, an undue cost and un-necessary discomfort.

2000 ◽  
Vol 11 (4) ◽  
pp. 250-253 ◽  
Author(s):  
S Newmann ◽  
P Sarin ◽  
N Kumarasamy ◽  
E Amalraj ◽  
M Rogers ◽  
...  

A retrospective study was conducted on 134 HIV-infected females evaluated at an HIV/AIDS centre in south India to characterize their socio-demographics, HIV risk factors and initial clinical presentations. The mean age was 29 years; 81% were housewives; 95% were currently or previously married; 89% reported heterosexual sex as their only HIV risk factor; and 88% reported a history of monogamy. The majority were of reproductive age, thus the potential for vertical transmission of HIV and devastating impacts on families is alarming. Nearly half of these women initially presented asymptomatically implying that partner recruitment can enable early HIV detection. Single partner heterosexual sex with their husband was the only HIV risk factor for the majority of women. HIV prevention and intervention strategies need to focus on married, monogamous Indian women whose self-perception of HIV risk may be low, but whose risk is inextricably linked to the behaviour of their husbands.


Author(s):  
Ashwini Shenai ◽  
Savitha G

Objective: Metabolic syndrome (MetS) is a common health problem worldwide. According to third national health and nutrition examination survey criteria, about 47 million people have MetS. It is defined as having three or more of the following five risk factors including abdominal obesity, increased triglyceride levels, low-density lipoprotein cholesterol level, elevated blood pressure, and elevated fasting glucose levels. These components of MetS are major risk factors for the development of chronic kidney disease (CKD) also. CKD is a major public problem and it is a major risk factor for the development of cardiovascular disease. Hence, the aim of the current study was to evaluate the association between MetS and CKD.Methods: A total of 50 patients reporting to Saveetha Dental College and Hospitals were enrolled into the study which includes 25 patients with MetS and 25 healthy individuals. 5 mL of venous blood was collected and centrifuged. Then, it is analyzed for fasting blood sugar (FBS), serum triglycerides, serum urea, and creatinine using the standard kit method. The data obtained were subjected to statistical analysis using the SPSS software.Results: The mean body mass index, FBS, serum creatinine, and triglyceride levels were higher in MetS patients in comparison to healthy individuals. The mean body mass index (BMI), FBS, serum urea, serum creatinine, and triglyceride levels in the control group and MetS group were 27.75±3.67, 84.8±12.5, 17.52±5.2, 0.91±0.17, and 96.5±60.13 and 35.14±4.25, 108.8±34.69, 21.4±5.9, 1.0±0.14, and 239.76±51.21, respectively. There was a significant difference in the mean BMI, FBS, urea, creatinine, and triglyceride levels of the above group.Conclusion: Serum urea and creatinine levels were significantly higher in MetS individuals. Hence, MetS could be a one of the risk factors for the development of CKD.


2011 ◽  
Vol 21 (12) ◽  
pp. 1870-1878 ◽  
Author(s):  
Ignazio Tarantino ◽  
Renè Warschkow ◽  
Thomas Steffen ◽  
Philipp Bisang ◽  
Bernd Schultes ◽  
...  

2018 ◽  
Vol 25 (1) ◽  
pp. 39-44
Author(s):  
Ahmed E. Altyar

Little is known about the effects of gastric bypass on the absorption of prescription medications in the post-operative state. This poses a considerable clinical dilemma especially that the prevalence of morbid obesity continues to escalate in the United States of America, and as a result the number of gastric bypass procedures performed each year has similarly increased dramatically. The author presented a case of a 45-year-old male with refractory hypertension, secondary to mechanical complications after a Roux-en-Y gastric bypass procedure due to anatomical alteration contributing to pill retention and change in medications' pharmacokinetics. Investigations for secondary causes of hypertension were made, patient’s blood pressure had become exceedingly difficult to control after his Roux-en-Y gastric bypass procedure and had only been controlled with IV medications. Further investigations confirmed the diagnosis of a mechanical gastrointestinal complication.  


2020 ◽  
Author(s):  
Simon Crequit ◽  
Diane Korb ◽  
Cécile Morin ◽  
Thomas Schmitz ◽  
Olivier Sibony

Abstract Background: The aim of this study was to identify characteristics of pregnant women with obesity that contribute to increased cesarean rate.Methods: Retrospective cohort in a single academic institution between 2012 and 2019. Women who delivered during this period were classified according to the Robson classification. Women with normal body mass index (N=11797) and with obesity (N=2991) were compared. The contribution of each Robson group to the overall caesarean rate were compared.Results: The overall cesarean rate was higher for women with (28.1%) than without (14.2%, p < 0.001) obesity. This result came mainly from Robson group 5a (history of one cesarean). After adjustment for medical factors within this group, the association between maternal obesity and cesarean during labor was significant.Conclusions: The higher cesarean rate in women with obesity is explained by Robson group 5a in which obesity is an independent risk factor of in labor cesarean delivery.


2023 ◽  
Vol 83 ◽  
Author(s):  
R. Muzaffar ◽  
M. A. Khan ◽  
M. H. Mushtaq ◽  
M. Nasir ◽  
A. Khan ◽  
...  

Abstract The present study was designed to evaluate the strength of association of raised plasma homocysteine concentration as a risk factor for coronary heart disease independent of conventional risk factor. It was a case control study conducted at Punjab Institute of Cardiology Lahore. A total of 210 subjects aged 25 to 60 years comprising of 105 newly admitted patients of CHD as cases and 105 age and sex matched healthy individuals with no history of CHD as control were recruited for the study. Fasting blood samples were obtained from cases and controls. Plasma homocysteine was analyzed by fluorescence polarization immunoassay (FPIA) method on automated immunoassay analyzer (Abbott IMX). Total cholesterol, triglyceride and HDL cholesterol were analyzed using calorimetric kit methods. The concentration of LDL cholesterol was calculated using Friedewald formula. The patients were also assessed for traditional risk factors such as age, sex, family history of CVD, hypertension, smoking and physical activity, and were compared with control subjects. The collected data was entered in SPSS version 24 for analysis and interpretation.The mean age in controls and experimental groups were 43.00± 8.42 years and 44.72± 8.59 years with statistically same distribution (p- value= 0.144). The mean plasma homocysteine for cases was 22.33± 9.22 µmol/L where as it was 12.59±3.73 µmol/L in control group. Highly significant difference was seen between the mean plasma level of homocysteine in cases and controls (p˂0.001).Simple logistic regression indicates a strong association of coronary heart disease with hyperhomocysteinemia (OR 7.45), which remained significantly associated with coronary heart disease by multivariate logistic regression (OR 7.10, 95%C1 3.12-12.83, p=0.000). The present study concludes that elevated levels of Plasma homocysteine is an independent risk factor for coronary heart disease independent of conventional risk factors and can be used as an indicator for predicting the future possibility for the onset of CVD.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Simon Crequit ◽  
Diane Korb ◽  
Cécile Morin ◽  
Thomas Schmitz ◽  
Olivier Sibony

Abstract Background The aim of this study was to identify characteristics of pregnant women with obesity that contribute to increased cesarean rate. Methods Retrospective cohort in a single academic institution between 2012 and 2019. Women who delivered during this period were classified according to the Robson classification. Women with normal body mass index (N = 11,797) and with obesity (N = 2991) were compared. The contribution of each Robson group to the overall caesarean rate were compared. Results The overall cesarean rate was higher for women with (28.1%) than without (14.2%, p < 0.001) obesity. This result came mainly from Robson group 5a (history of one cesarean). After adjustment for medical factors within this group, the association between maternal obesity and cesarean during labor was significant. Conclusions The higher cesarean rate in women with obesity is explained by Robson group 5a in which obesity is an independent risk factor of in labor cesarean delivery.


2005 ◽  
Vol 71 (3) ◽  
pp. 231-234 ◽  
Author(s):  
Anthony Charles ◽  
Shirley Domingo ◽  
Aaron Goldfadden ◽  
Jason Fader ◽  
Richard Lampmann ◽  
...  

Small bowel obstruction is an unusual complication of pregnancy. Its occurrence after Roux- en-Y gastric bypass (RYGB) for morbid obesity complicated by pregnancy is rare. Morbid obesity describes body weight at least 100 lb over the ideal weight, or a body mass index (BMI) ≥40. Surgery offers the only viable treatment option with long-term weight loss and maintenance. This case report involves a 23-year-old female at 25 weeks gestation with a 1-day history of diffuse abdominal pain and vomiting. She had a RYGB with a 15 cc micropouch 6 months prior to the commencement of this pregnancy. All radiologic investigations were normal. Esophagogastroscopy was performed revealing an ischemic Roux limb of the gastric bypass. At laparotomy, an internal hernia involving the afferent limb was identified at the site of the Roux anastomosis compromising portions of both the afferent and Roux limbs. Nonviable portions of both the afferent and Roux limbs were resected. Gastrointestinal continuity was achieved by fashioning a gastro-gastrostomy and a jejuno-jejunostomy, thus reversing the original gastric bypass procedure. The immediate postoperative period was complicated by fetal demise. With the increase in bariatric surgery, small bowel ischemia after Roux- en-Y gastric bypass will most likely become more prevalent, particularly in women of childbearing age.


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