scholarly journals Turnover of Plasma Kininogens in Rhesus Monkeys

1977 ◽  
Author(s):  
T. Yamada ◽  
D.A. Wing ◽  
J.V. Pierce
Keyword(s):  
Molecular Weight ◽  
Rhesus Monkeys ◽  
Low Molecular Weight ◽  
Time Intervals ◽  
Exponential Equation ◽  
Double Exponential ◽  
Minimal Difference ◽  
The Difference ◽  
Fogarty International Center ◽  
Gamma Counter

Radiolabelled purified plasma kininogens were injected into healthy rhesus monkeys for the purpose of studying their normal metabolic turnover. Human kininogen was purified using affinity chromatography and further fractionated into high molecular weight (HMW) and low molecular weight (LMW) proteins as described by Pierce and Guimaraes (Fogarty International Center Proceedings No. 27, pp. 113-119, 1976). The kininogens were labelled with 125I using either the choramine-T or microdiffusion techniques. Labelled mixed kininogen, LMW kininogen, and HMW kininogen preparations were injected into 6, 4, and 6 rhesus monkeys respectively. Blood samples were drawn at various time intervals, and assayed in a gamma counter. The disappearance of injected labelled kininogen from the intravascular compartment could be expressed as a double exponential equation. The difference between the half-life of HMW kininogen (26.0 ± 1.6 h) (± SE) and that of LMW kininogen (20.2 ± 2.1 h) was only marginal (P >0.05). In contrast there was a highly significant (P < 0.001) difference in their fractional catabolic rates (1.12 ± 0.09 day-1 for HMW kininogen and 2.05 ± 0.12 day-1 for LMW kininogen). These observations indicate that although there is a minimal difference in the metabolic rates of intravascular HMW and LMW kininogens, a considerable difference exists in their rates of flux between the intravascular and extravascular spaces.

ANALISA KANDUNGAN BETA-GLUKAN LARUT AIR DAN LARUT ALKALI DARI TUBUH BUAH JAMUR TIRAM (Pleurotus ostreatus) DAN SHIITAKE (Lentinus edodes)

2013 ◽  
Vol 13 (3) ◽  
Author(s):  
Netty Widyastuti ◽  
Teguh Baruji ◽  
Henky Isnawan ◽  
Priyo Wahyudi ◽  
Donowati Donowati
Keyword(s):  
Molecular Structure ◽  
Molecular Weight ◽  
Immune System ◽  
Pleurotus Ostreatus ◽  
Water Soluble ◽  
Low Molecular Weight ◽  
Lentinus Edodes ◽  
Beta Glucan ◽  
Oyster Mushrooms ◽  
The Difference

Beta glucan is a polysaccharide compound, generally not soluble inwater and resistant to acid. Beta glucan is used as an immunomodulator (enhancing the immune system) in mammals is usually a beta-glucan soluble in water, easily absorbed and has a low molecular weight. Several example of beta-glucan such as cellulose (β-1 ,4-glucan), lentinan (β-1 0.6-glucan) and (β-1 ,3-glucan), pleuran (β-1, 6 and β-1 ,3-glucan) are isolated from species of fungi Basidiomycota include mushrooms (Pleurotus ostreatus) and shiitake (Lentinus edodes).The purpose of thisresearch activity is to obtain beta-glucan compound that can be dissolved in water and in alkali derived from fungi Basidiomycota, i.e, Oyster mushrooms (Pleurotus ostreatus) and shiitake (Lentinus edodes). The result of beta-glucan compared to characterize the resulting beta glucan that is molecular structure . The difference of beta glucan extraction is based on the differences in solubility of beta-glucan. Beta glucan could be water soluble and insoluble water.

scholarly journals Selection of inorganic-based fertilizers in forward osmosis for water desalination

2015 ◽  
Vol 4 (2) ◽  
pp. 319-329 ◽  
Author(s):  
Tripti Mishra ◽  
RK Srivastava
Keyword(s):  
Molecular Weight ◽  
Water Flux ◽  
Forward Osmosis ◽  
Direct Application ◽  
Water Desalination ◽  
Performance Ratio ◽  
Low Molecular Weight ◽  
Inorganic Fertilizers ◽  
The Difference ◽  
Selection Of

The current study aims at the selection of an appropriate draw solute for forward osmosis process. Separation and recovery of the draw solute are the major criteria for the selection of draw solute for forward osmosis process. Therefore in this investigation six inorganic fertilizers draws solute were selected. The selections of inorganic fertilizers as draw solute eliminate the need of removal and recovery of draw solute from the final product. The final product water of forward osmosis process has direct application in agricultural as nutrient rich water for irrigation. These inorganic fertilizers were tested based on their water extraction (water flux) capacity. This experimental water flux was compared with the observed water flux. It was noted that the observed water flux is much higher than the attained experimental water flux. The difference of these two fluxes was used to calculate the performance ratio of each selected fertilizer. Highest performance ratio was shown by low molecular weight compound ammonium nitrate (22.73) and potassium chloride (21.03) at 1 M concentration, whereas diammonium phosphate (DAP) which has highest molecular weight among all the selected fertilizer show the lowest performance ratio (10.02) at 2 M concentration. DOI: http://dx.doi.org/10.3126/ije.v4i2.12660 International Journal of Environment Vol.4(2) 2015: 319-329

scholarly journals Low-temperature dynamics in amorphous polymers and low-molecular-weight glasses—what is the difference?

2011 ◽  
Vol 13 (5) ◽  
pp. 1843-1848 ◽  
Author(s):  
Ivan Yu. Eremchev ◽  
Yury G. Vainer ◽  
Andrei V. Naumov ◽  
Lothar Kador
Keyword(s):  
Molecular Weight ◽  
Low Temperature ◽  
Amorphous Polymers ◽  
Low Molecular Weight ◽  
Temperature Dynamics ◽  
The Difference

Influence of Botanical Species and Geographical Origin on the Content of Low Molecular Weight Phenolic Compounds of Woods Used in Portuguese Cooperage

Holzforschung ◽  
2000 ◽  
Vol 54 (3) ◽  
pp. 255-261 ◽  
Author(s):  
Sara Canas ◽  
M. Conceição Leandro ◽  
M. Isabel Spranger ◽  
A. Pedro Belchior
Keyword(s):  
Molecular Weight ◽  
Phenolic Compounds ◽  
Geographical Origin ◽  
Castanea Sativa ◽  
Total Content ◽  
Low Molecular Weight ◽  
Qualitative And Quantitative ◽  
Botanical Species ◽  
The Difference ◽  
Chestnut Wood

Summary The influence of botanical species (Quercus and Castanea sativa) and geographical origin (Portugal—three different sites, France and North America) on the qualitative and quantitative content of some extractable low molecular weight phenolic compounds was assessed by HPLC. Chestnut wood had the highest total content of low molecular weight phenolic compounds, followed by the Portuguese oaks and the French oaks, whereas the American oak had the lowest content of these compounds. The contents of phenolic acids, phenolic aldehydes, scopoletin and umbelliferone were significantly different among the studied woods. Both the botanical species and the geographical origin affect the content of low molecular weight organic compounds of woods used in Portuguese cooperage. The results also show that the botanical species seem to be more important than the geographical origin to explain the difference in the wood phenolic composition. So, the separation of trees according to their origin is of considerable interest for coopers and winemakers to choose wisely the woods for the ageing of brandies.

Thrombocytopenia Is More Common and Nadir Occurs Earlier with Unfractionated Heparin Than with Low Molecular Weight Heparin - Results from the Prospective Catch Registry.

Blood ◽  
2004 ◽  
Vol 104 (11) ◽  
pp. 2197-2197
Author(s):  
Stephan Moll ◽  
Charles S. Abrams ◽  
Lawrence Rice ◽  
Richard C. Becker ◽  
Peter B. Berger ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Platelet Count ◽  
Unfractionated Heparin ◽  
Low Molecular Weight Heparin ◽  
Heparin Therapy ◽  
P Value ◽  
Low Molecular Weight ◽  
Life Threatening ◽  
The Difference ◽  
Time To Onset

Abstract Background : Thrombocytopenia in the patient on heparin can have various etiologies, including benign reversible causes and serious, potentially life-threatening ones, such as heparin induced thrombocytopenia (HIT). Knowledge about the prevalence of and timecourse of thrombocytopenia in heparin-treated patients may be helpful to develop systems of alerting clinicians to possible HIT and determining how frequently to check blood counts to detect thrombocytopenia that may be heralding HIT. Methods : The CATCH registry is a prospective registry of inpatients enrolled between March 2003 and April 2004 at over 50 US hospitals in 3 strata: [1] receiving > 96 hours of unfractionated heparin (UFH) or low molecular weight heparin (LMWH), [2] developing thrombocytopenia (platelets >50% reduction from baseline or <150,000/mm3) in the cardiac care unit and [3] patients on whom HIT tests were ordered. Here we present the data of the prolonged heparin stratum. Results : 1,121 and 861 patients received UFH and LMWH, respectively, for > 96 hours. A platelet count decrease of > 50 % from baseline was seen more frequently in patients on UFH than in patients on LMWH (10.7% and 7.9 %, respectively; p = 0.03). The parameters that predicted development of thrombocytopenia in the UHF group were length of heparin therapy, body mass index, and admission to a cardiac service; the only parameter predicting thrombocytopenia in the LMWH group was length of LMWH treatment. Of the patients with decreased platelet count by > 50 % from baseline (for UFH n = 120; for LMWH n = 68), this drop occurred in the UFH group at a median of 3.0 days after initiation of heparin and at a median of 4.0 days in the LMWH group. The difference in timing between the 2 groups was not statistically significant (p = 0.205). The platelet nadir was reached after a median /mean of 4.0 / 7.4 days in the UFH group, and 8.0 / 11.4 days in the LMWH group. This was statistically significantly different between the 2 groups (p-value = 0.0025). Conclusions : A platelet count decrease of > 50 % from baseline occurs frequently in inpatients treated with prolonged heparin. It occurs slightly more frequently on UFH than on LMWH. The median time to onset of thrombocytopenia (> 50 % decrease from baseline) occurs early, at 3–4 days. Daily platelet count checks in the first few days of heparin therapy may be helpful to rapidly discover thrombocytopenia that may then prompt HIT testing.

Subcutaneous Low Molecular Weight Heparin versus Subcutaneous Unfractionated Heparin in the Treatment of Deep Vein Thrombosis: a Polish Multicenter Trial

1992 ◽  
Vol 68 (01) ◽  
pp. 014-018 ◽  
Author(s):  
S Lopaciuk ◽  
A J Meissner ◽  
S Filipecki ◽  
K Zawilska ◽  
J Sowier ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Deep Vein Thrombosis ◽  
Unfractionated Heparin ◽  
Low Molecular Weight Heparin ◽  
Multicenter Trial ◽  
Fixed Dose ◽  
Low Molecular Weight ◽  
Vein Thrombosis ◽  
The Difference ◽  
Deep Vein

SummaryIn a prospective multicenter trial, 149 consecutive patients with phlebographically proven proximal and/or distal deep vein thrombosis of the leg were randomly allocated to receive subcutaneously for 10 days either low molecular weight heparin CY 216 (Fraxiparine) in a fixed dose or unfractionated heparin (UFH) in doses adjusted according to the activated partial thromboplastin time. Pre- and post-treatment phlebograms were assessed blindly using the Arnesen’s score system in 134 patients available for analysis of the treatment efficacy. The mean phlebographic score after 10 days of treatment was significantly decreased in both groups (p <0.001) in comparison with the baseline score but the difference in score changes between the two groups was not statistically significant. There was an improvement in 45/ 68 patients (66%) in the Fraxiparine group and in 32/66 patients (48%) in the UFH group, and an increase in the thrombus size in 10/68 (15%) and 12/66 (18%), respectively. One symptomatic non-fatal pulmonary embolism and one major bleeding episode were observed in the UFH group. During a follow-up period of 3 months, two rethromboses had occurred in the UFH group and none in the Fraxiparine group. It is concluded that subcutaneous fixed dose Fraxiparine is safe and at least as effective as subcutaneous adjusted UFH in the treatment of deep vein thrombosis.

scholarly journals Properties and structure of high temperature resistant cyanate ester/polyethersulfone blends using solvent-free toughening approach

2020 ◽  
Author(s):  
Lyaysan Amirova ◽  
Fabian Schadt ◽  
Markus Grob ◽  
Christian Brauner ◽  
Thomas Ricard ◽  
...  
Keyword(s):  
Molecular Weight ◽  
High Temperature ◽  
Network Formation ◽  
Mechanical Analysis ◽  
Solvent Free ◽  
Cyanate Ester ◽  
Low Molecular Weight ◽  
Scanning Calorimetry ◽  
Molecular Weights ◽  
The Difference

AbstractA high temperature resistant novolac cyanate ester was blended with polyethersulfone (PES) with different molecular weights using the solvent-free approach. The phase separation, curing behavior and thermal properties were studied using hot stage microscopy, differential scanning calorimetry and dynamic mechanical analysis. Results showed the difference in the morphology for blends with different molecular weight PES explained by possible network formation. The influence of PES content on the glass transition temperature and mechanical properties was investigated. The most significant toughening effect (increase of 132% in fracture toughness) was achieved on a functionalized low molecular weight PES (20 parts per hundred of resin, phr). Rheology investigation allowed to estimate the optimal content of PES (15 phr) for further prepreg manufacturing.

Stent encrustation in feline and human artificial urine: does the low molecular weight composition account for the difference?

Urolithiasis ◽  
2013 ◽  
Vol 41 (6) ◽  
pp. 481-486 ◽  
Author(s):  
M. Shafat ◽  
K. Rajakumar ◽  
H. Syme ◽  
N. Buchholz ◽  
M. M. Knight
Keyword(s):  
Molecular Weight ◽  
Low Molecular Weight ◽  
Weight Composition ◽  
Artificial Urine ◽  
The Difference

Crosslinking and Mechanical Properties of Liquid Rubber. I. Curative Effect of Aliphatic DIOLS

1979 ◽  
Vol 52 (5) ◽  
pp. 920-948 ◽  
Author(s):  
Yuji Minoura ◽  
Shinzo Yamashita ◽  
Hiroshi Okamoto ◽  
Tadao Matsuo ◽  
Michiaki Izawa ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Molecular Weight ◽  
Low Molecular Weight ◽  
Structure Property ◽  
X Ray Diffraction ◽  
Curative Effect ◽  
Polyurethane Elastomers ◽  
X Ray ◽  
Structure Property Relationships ◽  
The Difference

Abstract The structure-property relationships of polyurethane elastomers derived from a liquid hydroxyl-terminated polybutadiene/low molecular weight aliphatic diol/diisocyanate system were studied. The effects of the amount of low molecular weight diol on the mechanical properties of the elastomer were discussed on the basis of the results of stress-strain, swelling, dynamic viscoelasticity, x-ray diffraction, etc. It was found that some particular combinations of low molecular weight diol and diisocyanate specifically affect the properties of elastomers. When the mechanical properties of the elastomers were plotted against the number of methylene carbons in the low molecular weight diol, characteristic zigzag patterns were obtained. These patterns were explained by the difference in the packing and the dependence of the strength of intermolecular hydrogen bonding on whether the number of the methylene carbons was even or odd. This assumption was confirmed by x-ray diffraction.

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