scholarly journals Healing Process Following Application of Set or Fresh Mineral Trioxide Aggregate as a Root-End Filling Material

2011 ◽  
Vol 05 (01) ◽  
pp. 019-023 ◽  
Author(s):  
Mehdi Habibi ◽  
Jamileh Ghoddusi ◽  
Ataollah Habibi ◽  
Nooshin Mohtasham

ABSTRACTObjectives: An unsuccessful attempt to reach the apical area or to place the retrograde material is a major difficulty in periradicular surgery. The aim of this study was to compare the histological evaluation of the healing process following an orthograde versus a retrograde application of mineral trioxide aggregate (MTA) as a root-end filling material during apical surgery on cats’ teeth in order to find out whether orthograde placement of MTA before surgery can be used instead of retrograde placement during surgery. Methods: In this experimental study, 24 canine teeth in 12 mature and healthy cats were filled with either MTA or gutta-percha in an orthograde manner. Two weeks later, the teeth with MTA were surgically exposed and resected to the set-MTA within the canals. The teeth previously filled by gutta-percha were also surgically exposed, and retrograde cavities were prepared at the root ends and filled with fresh-MTA. After 8 weeks, the animals were euthanized by vital perfusion. Six-micron histological slices were prepared from samples, stained by Hematoxylin & Eosin, and histologically studied by means of a light microscope. The collected data was analyzed by the Chi-square and the T-test. Results: One of the samples in the fresh-MTA group was omitted during processing because of inappropriate sectioning. In the set-MTA group, 5 out of 12 showed chronic abscess, while in the fresh-MTA group, 2 out of 11 were discovered to have chronic abscess; however, no significant difference was observed (P>.05). Hard tissue healing (cementum, bone, cementum + bone formation) in the set-MTA and fresh-MTA groups were 7 out of 12 and 9 out of 11, respectively. While healing seemed more likely to occur in the fresh-MTA group, the difference was statistically insignificant (P>.05). The magnitude of bone, cementum, or bone and cementum formation showed slight differences between the two groups; however, the figures failed to show any marked differences (P>.05). Conclusions: Orthograde placement of MTA could be used as an obturation material before surgery. In this way, after root-end resection, there would be no need for root-end preparation and filling procedures. (Eur J Dent 2011;5:19-23)

2017 ◽  
Vol 18 (11) ◽  
pp. 1045-1050 ◽  
Author(s):  
Maryam Forghani ◽  
Hamid Jafarzadeh ◽  
Jamileh Ghoddusi ◽  
Amir Maghsudlu ◽  
Amirhossein Jafarian

ABSTRACT Aim Platelet-rich plasma (PRP), which is a concentration of growth factors found in platelets, may be a suitable material for pulp regeneration. The aim of this animal study was a histological evaluation of PRP on pulp regeneration in nonvital teeth with immature apices. Materials and methods A total of 40 premolar dogs’ teeth were chosen for this study. After general anesthesia, the teeth were exposed, and subsequently, pulps were removed and the cavities were opened to the oral cavity. After 2 weeks, root canals were irrigated and disinfected with sodium hypochlorite with noninstrumentation technique, and triple antibiotic paste was placed inside the canals. Cavities were sealed with a temporary restoration. About 4 weeks later, canals were irrigated again and the teeth were randomly divided into three groups. Bleeding was evoked with overinstrumentation, then experimental materials for each group [PRP, mineral trioxide aggregate (MTA), and parafilm respectively] were placed over the bleeding, and orifices were sealed with MTA and glass ionomer. After 3 months, dogs were sacrificed and the teeth were separated from the jaws and sections prepared for histological evaluation. Results Regeneration was shown in 44.7% of the samples. About 47.3% of the samples in the MTA group and 42.1% of the samples in the PRP group showed regeneration; however, no regeneration was observed in the parafilm group. Chi-square test showed no significant difference between groups I and II. The soft regenerative tissue included pulp-like tissue and vessels. Mineralized regenerative tissue included cementumlike, periodontal ligament-like, and bone-like tissues. No normal pulp and nerve tissue were observed. Conclusion Both PRP and MTA may be ideal scaffolds to accelerate the regeneration process. Clinical significance Pulp repair in immature permanent teeth with weak roots has a better outcome than replacement of the pulp with gutta-percha or biomaterials. How to cite this article Ghoddusi J, Maghsudlu A, Jafarzadeh H, Jafarian A, Forghani M. Histological Evaluation of the Effect of Platelet-rich Plasma on Pulp Regeneration in Nonvital Open Apex Teeth: An Animal Study. J Contemp Dent Pract 2017;18(11):1045-1050.


2021 ◽  
Vol 33 (2) ◽  
pp. 130
Author(s):  
Ghaisani Khansa ◽  
Sarianoferni Sarianoferni ◽  
Yongki Hadinata Wijaya

Pendahuluan: Bahan pengisi saluran akar yang digunakan hingga saat ini adalah gutta percha yang dalam aplikasinya harus dikombinasikan dengan sealer saluran akar. Sealer yang baik harus memiliki skala radiopasitas yang tinggi sehingga dapat dibedakan densitasnya dengan jaringan disekitarnya, tujuannya supaya sealer dapat diidentifikasi maupun di monitor bila terjadi kerusakan pada gigi setelah dilakukan perawatan. Tujuan penelitian ini menganalisis perbedaan radiopasitas antara sealer berbahan dasar resin epoksi, sealer berbahan MTA, dan sealer berbahan dasar biokeramik pada teknik radiografi periapikal dengan menggunakan densitometer. Metode: Jenis penelitian observasional analitik dengan pendekatan cross sectional. Dua puluh tujuh sampel penelitian dibagi menjadi tiga kelompok. Kelompok I sealer berbahan dasar resin epoksi. Kelompok II sealer berbahan dasar MTA. Kelompok III sealer berbahan dasar biokeramik. Ketiga kelompok dimasukkan ke dalam cincin plastik berukuran 10 x 1 mm, kemudian dilakukan pengambilan gambar dengan teknik radiografi periapikal digital menggunakan dental x-ray yang beroperasi di 70 KVp dan 8 mA dengan jarak fokus ke jarak 30 cm dan eksposur distandarisasi untuk 0,25 detik. Pengamatan dilakukan dengan menggunakan densitometer, data yang dihasilkan kemudian dianalisis menggunakan uji One Way ANOVA. Hasil: Hasil penelitian menunjukan bahwa dari ketiga kelompok terdapat perbedaan radiopasitas secara signifikan (p<0,05). Sealer berbahan dasar resin epoksi (12,9 mmAl) secara signifikan lebih radiopak daripada sealer berbahan dasar biokeramik (8,04 mmAl) dan sealer berbahan dasar MTA (6,90 mmAl). Radiopasitas dipengaruhi oleh komposisi bahan kimia, media kontras anorganik, nomor atom, komposisi radiopacifier dan densitas pada sealer. Simpulan: Sealer berbahan dasar resin epoksi memiliki radiopasitas tertinggi dibandingkan dengan yang berbahan dasar MTA dan biokeramik. ABSTRACTIntroduction: Nowadays, gutta-percha is widely used as the root canal filling material. However, in its application, it must be combined with a root canal sealer. A good sealer must have a high radiopacity scale value to distinguish its density from the surrounding tissue. In addition, the sealer must be able to be identified and monitored concerning the damage to the teeth after treatment. The purpose of this study was to analyse the radiopacity differences between sealers based on epoxy resin, mineral trioxide aggregate (MTA), and bioceramics on periapical radiographs using a densitometer. Methods: This research was analytic observational with a cross-sectional method. Twenty-seven study samples were divided into three groups. Group I consisted of an epoxy resin-based resin. Group II consisted of an MTA-based sealer. Group III consisted of a bioceramic-based sealer. The three groups were put in a 10 x 1 mm plastic ring. The radiographic images were taken using digital periapical radiography using dental x-rays operating at 70 KVp and 8 mA with a focal distance of 30 cm and exposure standardised to 0.25 seconds. Observations were performed using a densitometer, and the resulting data were then analysed using the One-Way ANOVA test. Results: The results showed that there was a significant difference in radiopacity (p<0.05). Epoxy resin-based sealers (12.9 mmAl) were significantly more radiopaque than bioceramic-based sealers (8.04 mmAl) and MTA-based sealers (6.90 mmAl). Radiopacity is influenced by chemical composition, inorganic contrast medium, atomic number, radiopacifier composition and sealer density. Conclusions: Epoxy resin-based sealers have the highest radiopacity compared to MTA and bioceramic-based sealers.


SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A153-A153
Author(s):  
Goeun Kim ◽  
Hyojin Nam ◽  
Huisu Jeon ◽  
Sooyeon Suh

Abstract Introduction Bedtime Procrastination (BP) is defined as the behavior of voluntarily delaying going to bed, without having external reasons for doing so. Recent research on procrastination behavior suggests that when negative emotions are elevated, procrastination behaviors can be triggered in order to find pleasure to avoid and alleviate them. Procrastination can also occur when there is difficulty regulating emotions. In addition, the reason for bedtime procrastination may be different depending on whether the individuals present with insomnia. According to previous studies, patients with insomnia may exhibit more pronounced negative avoidance of bedtime due to prolonged sleeplessness. Therefore, this study compared the difference between of the bedtime procrastination and the emotional regulation strategies between the insomnia group and the healthy group. Methods This study was conducted in 582 adults (mean age 23.06 ±2.16 years), 81.6% females. Individuals scoring higher than 15 on the Insomnia Severity Index (ISI) were classified into the insomnia group (n=375), and those less than 15 were classified into the healthy group (n=207). Participants completed the Bedtime Procrastination Scale (BPS), Emotional Regulation Strategies Checklist. Data was analyzed using descriptive statistics, chi square test, and independent t tests. Results The insomnia group had significantly higher bedtime procrastination scores than the healthy group (t=-6.241, p&lt;.001), and also the avoidant/distractive regulation style score was significantly higher (t=-1.969, p&lt;.05). In addition, the score of active regulation style was significantly lower in the insomnia group than in the healthy group (t=3.050, p&lt;.01). There was no significant difference between the two groups in the support-seeking regulation style. Conclusion Based on these results, it was confirmed that there was a difference in the bedtime procrastination and the emotional regulation strategies between the insomnia group and the healthy group. Support (if any) This work was supported by the Ministry of Education of the Republic of Korea and the National Research Foundation of Korea(NRF-2018S1A5A8026807)


2013 ◽  
Vol 24 (5) ◽  
pp. 482-486 ◽  
Author(s):  
Marili Doro Andrade Deonizio ◽  
Gilson Blitzkow Sydney ◽  
Antonio Batista ◽  
Roberto Pontarolo ◽  
Paulo Ricardo Bittencourt Guimarães ◽  
...  

This study evaluated the influence of apical patency, root filling removal technique and cleaning of the apical foramen, concerning the amount of debris extruded during root canal retreatment. Forty mandibular incisors were randomly assigned to 4 groups - GIM (n=10), GIIM (n=10), GIPT (n=10) and GIIPT (n=10), which were named according to leaving (I) or not (II) apical patency during canal preparation and filling removal technique (manual - M or ProTaper system - PT). After filling material removal, each specimen of each group had the apical foramen cleaned by sizes 15, 20 and 25 instruments, generating 12 subgroups: GIM15, GIM20, GIM25, GIIM15, GIIM20, GIIM25, GIPT15, GIPT20, GIPT25, GIIPT15, GIIPT20 and GIIPT25. Extruded filling debris was collected by a Milipore filtration system, an HV-durapore, 0.45 µm pore filter with a 25 mm diameter. The filters were weighed before and after the collection on an analytical scale (10–5 g), and the difference was calculated. The mean weight of extruded filling debris was analyzed statistically by Kruskal-Wallis and Friedman ANOVA tests (α=0.05). The mean values found in the groups (in mg) were: GIM (0.95±0.94), GIIM (0.47±0.62), GIPT (0.30±0.31) and GIIPT (0.32±0.44). There was no statistically significant difference among any of the groups or subgroups (p>0.05). ProTaper provided the smallest amount of extruded filling material, regardless of presence or absence of apical patency, followed by manual technique, without and with apical patency. Additional amounts of debris were collected during cleaning of the apical foramen, regardless of the instrument, presence/absence of patency or root filling removal technique.


2020 ◽  
Vol 6 (1) ◽  
pp. 1-25
Author(s):  
Wadii Snaibi

AbstractThe high plateaus of eastern Morocco are already suffering from the adverse impacts of climate change (CC), as the local populations’ livelihoods depend mainly on extensive sheep farming and therefore on natural resources. This research identifies breeders’ perceptions about CC, examines whether they correspond to the recorded climate data and analyses endogenous adaptation practices taking into account the agroecological characteristics of the studied sites and the difference between breeders’ categories based on the size of owned sheep herd. Data on perceptions and adaptation were analyzed using the Chi-square independence and Kruskal-Wallis tests. Climate data were investigated through Mann-Kendall, Pettitt and Buishand tests.Herders’ perceptions are in line with the climate analysis in term of nature and direction of observed climate variations (downward trend in rainfall and upward in temperature). In addition, there is a significant difference in the adoption frequency of adaptive strategies between the studied agroecological sub-zones (χ2 = 14.525, p <.05) due to their contrasting biophysical and socioeconomic conditions, as well as among breeders’ categories (χ2 = 10.568, p < .05) which attributed mainly to the size of sheep flock. Policy options aimed to enhance local-level adaptation should formulate site-specific adaptation programs and prioritise the small-scale herders.


Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
ghufran adnan ◽  
Osman Faheem ◽  
Maria Khan ◽  
Pirbhat Shams ◽  
Jamshed Ali

Introduction: COVID-19 pandemic has overwhelmed the healthcare system of Pakistan. There has been observation regarding changes in pattern of patient presentation to emergency department (ED) for all diseases particularly cardiovascular. The aim of the study is to investigate these changes in cardiology consultations and compare pre-COVID-19 and COVID-19 era. Hypothesis: There is a significant difference in cardiology consultations during COVID era as compared to non-COVID era. Method: We collected data retrospectively of consecutive patients who visited emergency department (ED) during March-April 2019 (non-COVID era) and March-April 2020 (COVID era). Comparison has been made to quantify the differences in clinical characteristics, locality, admission, type, number, and reason of Cardiology consults generated. Results: We calculated the difference of 1351 patients between COVID and non-COVID era in terms of cardiology consults generated from Emergency department, using Chi-square test. Out of which 880 (59%) are male with mean age of 61(SD=15). Analysis shows pronounced augmentation in number of comorbidities [Hypertension(6%), Chronic kidney disease (6%), Diabetes (5%)] but there was 36% drop in total cardiology consultations and 43% reduction rate in patient’s ED visit from other cities during COVID era. There was 60% decrease in acute coronary syndrome presentation in COVID era, but fortuitously drastic increase (30%) in type II myocardial injury has been noted. Conclusion: There is a remarkable decline observed in patients presenting with cardiac manifestations during COVID era. Lack in timely care could have a pernicious impact on outcomes, global health care organizations should issue directions to adopt telemedicine services in underprivileged areas to provide timely care to cardiac patients.


2017 ◽  
Vol 6 (1) ◽  
pp. 15-20
Author(s):  
Fatima Bichi ◽  
Dr. Shumaila Hanif

Diastasis Recti (DR) is a common muscular condition often present during and after pregnancy. This cross-sectional correlational study investigated the prevalence of DR among pregnant and postpartum women. A total of 250 pregnant and postpartum women were recruited using convenience sampling technique from obstetrics and gynaecology department, Aminu Kano Teaching Hospital, Kano, Nigeria. Age, body mass, height, BMI, parity, trimester, duration of DR postpartum, location of DR and DR status was recorded for each participant. Presence of DR was confirmed using the finger width method. Descriptive statistics of mean, SD, percentage were used to describe the data and determine the prevalence. Inferential statistics of Pearson’s and Spearman’s correlation were used to analyse the relationship between prevalence of DR and age, parity and duration of DR postpartum. Chi square was computed to determine the difference in prevalence of DR across trimesters. The result of this study indicated high prevalence of DR in post-partum and pregnant women (84% and 64.7% respectively); the most common location of DR was at the umbilicus in both pregnant and postpartum women. Prevalence of DR was high among the multigravida; and a significant relationship was found between prevalence of DR and age and parity of participants. There was a significant difference in prevalence of DR across the trimesters. It can be concluded that prevalence of DR among pregnant and postpartum women is high; age and parity are determinants of DR prevalence. Evaluation of DR should be considered as routine assessment in both pregnant and postpartum women.


2019 ◽  
pp. 097215091982551 ◽  
Author(s):  
Jabir Ali ◽  
Nadia Yusuf

This article analyses the difference in firm’s performance between enterprises with and without international quality certification. The study is based on a comprehensive survey of 9,281 Indian firms operating in different regions of the country, conducted under the World Bank’s Enterprise Survey. About 44.9 per cent of the firms have adopted international quality certification for enhancing the quality of their business processes. Chi-square statistics indicate that there is a significant difference in enterprise characteristics by international quality certification. Result of the analysis of variance indicates a significant difference in business performance with and without quality certification in terms of sales, employment growth rates and capacity utilization. Firms with international quality certification perceive comparatively less obstacles than those who are not having international quality certification. This study provides insights on differences in firms’ performance and business obstacles faced by them with or without international quality certification. This study can be helpful in designing policies for promoting certification and accreditation of product quality and processes across business enterprises in a focused manner.


2015 ◽  
Vol 03 (02) ◽  
pp. 071-079
Author(s):  
Rajender Singh ◽  
Ashu Gupta ◽  
Vishal Sharma

Abstract Objectives: This study was undertaken to evaluate the efficiency of two rotary nickel titanium instruments and hand instrumentation in removing gutta-percha and sealer from root canals. Study design: – 63 extracted human single rooted premolars were instrumented with K-files and filled using lateral compaction of gutta-percha (GP) and three different sealers. The teeth were randomly divided into three experimental groups of 21 specimens each. Removal of gutta-percha was performed with R-Endo retreatment files, Mtwo retreatment files and Hedstrom files. Time to reach working length and to eliminate filling material was also recorded. The specimens were sectioned for evaluation of the area of the remaining gutta-percha/sealer under stereomicroscope at 6X magnification. Photographs were taken for further analysis using computer image analysis program. The results were statistically analyzed using Analysis of variance (ANOVA) and Tukey’s honestly significant difference test. Results: The R-Endo retreatment system resulted in a smaller percentage of canal area covered by residual GP/sealer than in other groups, a significant difference was found between R-Endo and Mtwo group and between Hedstrom groups (P < 0.001). The Mean operating time was minimum with R-Endo group while it was found to be maximum with hand files. Conclusion: It was concluded that all test techniques left gutta-percha/sealer remnants within the root canal. The R-Endo retreatment files and Mtwo retreatment files system proved to be an efficient method for removing gutta-percha and sealer from single rooted premolars.


2019 ◽  
Vol 32 (04) ◽  
pp. 297-304 ◽  
Author(s):  
Harue Takizawa ◽  
Muneki Honnami ◽  
Takamasa Sakai ◽  
Akari Sasaki ◽  
Ayumi Sakamoto ◽  
...  

Objective The aim of this study was to evaluate the biomechanical properties of three different miniature locking plate systems used to fixate radial and ulnar fractures in toy breed dogs. Implant size, shape, material and locking systems differ, and their influence on the fracture healing process is unknown. In the present study, we aimed to investigate this matter in vivo using rabbit radial and ulnar fracture models. Study Design Eighteen rabbits were randomly divided into three groups, and the left radius and ulna were osteotomized to create fracture models. The osteotomies were then fixated using either the TITAN LOCK 1.5, Fixin micro or LCP 1.5 system. Radiographs were obtained 2, 3 and 4 weeks after surgery. Four weeks after surgery, the radiuses were collected and used for biomechanical testing or histological examinations. Results During the 4 weeks of observation, no adverse effects due to the implants occurred. The radiographic scores in each group did not differ significantly at any time point. The maximum load in the LCP group was significantly higher than that in the TITAN and Fixin groups. There was no significant difference in bending stiffness or work to failure among the groups. Initial fracture healing via woven bone was evident at histological evaluation. Conclusions All three miniature locking plate systems provided adequate fracture stabilization 4 weeks after surgery, despite their differences, in rabbit models.


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