Biobased Spiroimides from Itaconic Acid and Formamides: Molecular Targets for a Novel Synthetic Application of Renewable Chemicals
Keyword(s):
AbstractSpiroimides exhibit a wide range of biological activities, such as anticonvulsant, antiarrhythmic, and antihyperglycemic activities. Herein, a novel synthetic application of renewable chemicals, itaconic acid and formamides, is described. Proper exploitation of the reactivity of itaconic acid and formamide allows for the development of an efficient synthetic approach for the production of several new biobased spiroimides, spiro[dihydroquinolin-2-one-succinimides] and spiro[indolin-2-one-glutarimides], in excellent overall yields (up to 98%).
2020 ◽
Vol 16
(6)
◽
pp. 818-836
◽
2018 ◽
Click Reactions in Chemistry of Triterpenes - Advances Towards Development of Potential Therapeutics
2018 ◽
Vol 25
(5)
◽
pp. 636-658
◽
Keyword(s):
The Past
◽
2019 ◽
Vol 26
(23)
◽
pp. 4403-4434
◽
Keyword(s):
2020 ◽
Vol 26
(8)
◽
pp. 867-904
◽
2020 ◽
Vol 24
(5)
◽
pp. 473-486
◽