scholarly journals Medication Adherence and Its Determinants among Women of Cardiovascular Disease of Tertiary Care Hospital, Hyderabad

2020 ◽  
Vol 5 (04) ◽  
pp. 315-321
Author(s):  
Haritha Arnipalli ◽  
Sudha Bala ◽  
Harshal Pandve
Keyword(s):  
Medication Adherence ◽  
Health System ◽  
Tertiary Care ◽  
Developed Countries ◽  
Term Therapy ◽  
Care Hospital ◽  
Women Patients ◽  
Related Condition ◽  
Cross Sectional

Abstract Background and Aim Adherence to long-term therapy for chronic illnesses in developed countries averages to 50%. In developing countries, the rates are even lower. Poor adherence to long-term therapies severely compromises the effectiveness of treatment making this a critical issue in population health both from the perspective of quality of life and of health economics. Cardiovascular diseases (CVDs) are the most common disorders affecting most of the productive age group. Therefore, an attempt has been made to determine medication adherence using the Morisky medication adherence scale-4 (MMAS-4) and its determinants in women patients with CVD. Material and Methods A Hospital based cross-sectional study was conducted at outpatient block of General Medicine and Cardiology departments which included 175 women patients who were already diagnosed with CVD (with at least 3 months of medication) and those who were willing to give informed consent for participation. Semi structured questionnaire was used which consisted of sociodemographic variables, MMAS-4 to measure the level of adherence and various determinants such as socioeconomic, patient related, condition related, therapy related, and health system related. Results Prevalence of medication adherence among women of CVDs using MMAS-4 was high, medium, and low among 39, 51, and 10%, respectively. Significant determinants found were socioeconomic, patient related, health system, and therapy related. Conclusion Low-to-medium medication adherence was found to be high which needs to be addressed to reduce the morbidity and mortality associated with CVDs.

scholarly journals Non-Adherence to Anti-Hypertensive Treatment

2020 ◽  
Vol 32 (1) ◽  
pp. 126-129
Author(s):  
Shalini . ◽  
Manish Kumar Goel
Keyword(s):  
Side Effects ◽  
Tertiary Care ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Developed Countries ◽  
New Delhi ◽  
Care Hospital ◽  
Chi Square ◽  
Cross Sectional

Background: In developed countries, adherence among patients suffering from chronic diseases averages only 50%; in developing countries it is assumed to be much lower. Aims & objectives: To find out the prevalence of non-adherence to antihypertensive treatment among individuals seeking anti-hypertensive treatment from tertiary care hospital in New Delhi & to find out the factors related to non-adherence to the anti-hypertensive treatment among study subjects. Material and Methods: A cross-sectional hospital-based study was conducted from June to October 2018 among 150 diagnosed cases of hypertension. The drug adherence was assessed by using standard Brief Medication Questionnaire I (BMQ I) and to know the determinants of non-adherence a semi-structured (self-designed and pre tested) questionnaire was used. The association of different factors with adherence was analyzed by applying chi square (χ2) test. Results: Among total of 150 participants 44% were males and 56% were females. The magnitude of non-adherence to anti-hypertensive drugs was 35.3%. Side effects of anti-hypertensive drugs was significant risk factor for non-adherence to anti-hypertensive drugs and common reasons for non-adherence were unwanted side effects (64.2%) followed by worry about long term side effects (62.3%). Conclusion: Prevalence of non-adherence to anti-hypertensive drugs was quite high, most common reason for non-adherence to anti-hypertensive medication was unwanted side effects and worry about long term side effects.

scholarly journals Adverse drug reaction monitoring in patients of hypertension at a tertiary care hospital, Aurangabad, Maharashtra, India

2021 ◽  
Vol 10 (6) ◽  
pp. 720
Author(s):  
Shruti Chandra ◽  
Sukhmeen Kaur ◽  
Deepali Jayabhaye ◽  
Amol Ubale
Keyword(s):  
Antihypertensive Drugs ◽  
Patient Adherence ◽  
Tertiary Care ◽  
Term Therapy ◽  
Care Hospital ◽  
Cross Sectional ◽  
Hypertensive Patients ◽  
Long Term Therapy

Background: Hypertension is one of the highest prevailing diseases worldwide. Due to long term therapy antihypertensive drugs are commonly associated with adverse drug reactions (ADRs). Therefore, the study was conducted with the objective to examine the incidence of different types of ADRs in drug treated hypertensive patients.Methods: Present study was a prospective cross sectional observational study carried out in the outpatient of department of medicine of MGM hospital, a tertiary care teaching hospital, in Aurangabad. 320 diagnosed hypertensive patients were studied. Questionnaire was asked and their prescription were analysed and follow up was done.Results: Among 320 patient’s 75 patients were reported ADR. Males accounted for higher percent of ADRs 46 (61%) than females 29 (38.6%). Most of the patients 147 (55.9%) were on mono therapy. Calcium channel blocker was the frequently used class of drug, showed maximum number of ADR (30.6%) followed by ACE inhibitor (28%) and ARB (21.3%). As per WHO-UMC scale, type of reactions and their percentage were as certain (9.3%), Probable/ Likely (64%), possible (22.6%), and unlikely (4%). According to Naranjo scale most of the reactions were possible (64%). severity assessment is done by Hartwig and Siegel scale. No lethal ADR were reported. 4% reactions were severe, 32% were of moderate category and 64% were mild reactions.Conclusions: Such type of studies are helpful in selection of appropriate medicines for hypertensive patients, enhancing patient adherence with the therapy by selecting medicines of lesser ADR profile, reducing unnecessary economic burden to the patients due to unwanted effects of the therapy.

scholarly journals Medication Adherence among Mentally Ill Patients with comorbid- Substance Use Disorder

KYAMC Journal ◽  
2017 ◽  
Vol 6 (2) ◽  
pp. 602-609
Author(s):  
Nasim Jahan ◽  
Mohammad Muntasir Maruf ◽  
Md Faruk Hossain ◽  
Md Waziul Alam Chowdhury ◽  
Anwara Begum
Keyword(s):  
Substance Use ◽  
Medication Adherence ◽  
Mentally Ill ◽  
Substance Misuse ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Psychiatric Medication ◽  
Cross Sectional ◽  
Care Givers

Substance misuse is usually associated with poorer psychiatric medication adherence among mentally ill patients. Identifying proportion & predictors of medication adherence among patients with dual psychiatric and substance misuse problems is important because poor adherence is associated with relapse and re-hospitalization. This study was a descriptive cross sectional study conducted among the patients dually diagnosed with psychiatric and substance use disorders attending OPD in a tertiary care hospital of Dhaka city, during the period from May 2013 to November 2013. The main objective of the study was to explore the proportion of psychotropic medication adherence among the respondents who were on such medication for at least last 6 months (N=151). Respondents were selected purposefully. An informed consent was taken from the patients or care givers and data were collected using the questionnaire designed by the researcher based on Factors Influencing Neuroleptic Medication Taking Scale (FNIMTS). Diagnoses were done previously according to DSM-IV TR by psychiatrist appointed in inpatient and outpatient department. Questionnaire was filled up by the researcher by interviewing the patients and attending care givers as needed. Over half of the respondents (57.0%) admitted they had missed taking their medications on more than one occasion in the week prior to the interview. Thus this study found the proportion of medication adherence to be 43% among the respondents.KYAMC Journal Vol. 6, No.-2, Jan 2016, Page 602-609

Assessment of medication adherence patterns and various causes of non-adherence in long term therapies in a tertiary care hospital

2020 ◽  
Vol 13 (5) ◽  
pp. 2420
Author(s):  
Abel C. Mathew ◽  
M. V Aneesa ◽  
Ashitha Rehman ◽  
Dhanush Suresh ◽  
T.N.K. Suriyaprakash ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital

scholarly journals Cross sectional study on prevalence and medication adherence of hypertension and diabetes in a tertiary care hospital in Karimnagar, India

2018 ◽  
Vol 7 (4) ◽  
pp. 807
Author(s):  
S. Sre Akshaya Kalyani ◽  
Srihitha Pendota ◽  
Abhinay Sharma Katnapally ◽  
Dharanija Porandla ◽  
Sandeep Bheemreddy
Keyword(s):  
Medication Adherence ◽  
Health Care Professionals ◽  
Past History ◽  
Tertiary Care ◽  
Previous History ◽  
Individual Case ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional

Background: The study aimed to assess the prevalence of Hypertension (HTN), Diabetes mellitus(DM) and other diseases along with comorbid conditions, disease complications and also to assess medication adherence in a tertiary hospital in Karimnagar, Telangana, India.Methods: A Cross sectional study is performed by analysing a total of 500 patient’s individual case safety reports (ICSR). Prevalence of Hypertension and Diabetes along with most prescribed drugs are analysed. Medication adherence is analysed by using Morisky Medication adherence questionnaire scale (MMAS-4).Results: Patients with past history of DM, HTN and other diseases which was found to be 245 (49%) patients. Patients with highest disease prevalence were found to be with HTN (56.73%), DM (31.83%) followed by other diseases like asthma (8.57%), Cerebrovascular accident (4.89%) etc., Total of 66 Patients were ruled out with comorbid diseases. Patients with HTN+DM (47) were found to be highest followed by DM+HTN+CVA (4). MMAS-4 revealed 208 patients were using medication out of 245 patients with previous history. According to MMAS-4 most of the patients were with medium adherence (76). Prevalent drug used for HTN include Amlodipine and for DM Telmisartan+Hydrochlorthiazide.Conclusions: The study revealed that almost half of the admitted patients were with HTN and DM. The patients were counselled properly to adhere strictly to the prescription. Medication adherence to HTN and DM was found to be good in this study. Since the disease complications were also ruled out, the health care professionals are recommended to spread awareness on DM and HTN and disease management in order to control disease and improve health outcomes.

scholarly journals A study to evaluate risk factors and factors associated with non-adherence to the prescribed treatment among essential hypertensive patients attending tertiary care hospital

2020 ◽  
Vol 7 (9) ◽  
pp. 3623
Author(s):  
Venkat Sunil Bommishetty ◽  
Suresh Keshav Kumbhar
Keyword(s):  
Risk Factors ◽  
Medication Adherence ◽  
Life Style ◽  
Tertiary Care ◽  
Positive Family History ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Hypertensive Patients ◽  
Factors Associated

Background: Prevalence of hypertension is on rising trend with rise in life style and behavioral changes. It is also a major risk factor for most of the dreadful conditions like coronary artery disease, stroke, etc. Medication adherence would help in reducing the chance of occurrence of such complications. Thus objectives of study are 1) to evaluate the risk factors of hypertension among the diagnosed essential hypertensive patients; and 2) to assess the magnitude and the factors associated with non-adherence to the prescribed treatment.Methods: A hospital based cross-sectional study among 71 participants was conducted, using a pre-structured questionnaire and physical examination to assess risk factors of hypertension and CULIG’s 16 questionnaire medication adherence scale to assess the non-adherence. Data analysed with proportions and Chi square test.Results: Out of 71 participants, 60 (84.5%) were found to be non-adherent to their anti-hypertensive medication and factors like being male (p=0.0055), alcohol consumption (p=0.0485) and paid medication (p=0.0091) were found to be significantly affecting the medication non-adherence. Positive family history, sedentary life style, preference of extra salt and smoking/tobacco products usage were the most common risk factors of essential hypertension observed along with others.Conclusions: The participants who experienced the complications/ill effects of hypertension were more adherent as compared to others. Factors which are responsible for non -adherence need to be addressed and appropriate interventions required to improve adherence by educating the people about its importance in prevention of complications.

scholarly journals Medication adherence and its determinants amongst anti-hypertensive patients in a tertiary care hospital in Navi Mumbai

2020 ◽  
Vol 9 (2) ◽  
pp. 328
Author(s):  
Satyendra B. Badhe ◽  
Pramila V. Yadav ◽  
Pradnya S. Deolekar ◽  
Suvarna B. Badhe ◽  
Mihika Aggarwal
Keyword(s):  
Medication Adherence ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Sociodemographic Factors ◽  
Uncontrolled Hypertension ◽  
Care Hospital ◽  
Cross Sectional ◽  
Hypertensive Patients ◽  
Validated Questionnaire ◽  
Chi Squared

Background: Anti-hypertensive drugs can effectively control hypertension, subject to good adherence. Uncontrolled hypertension can lead to numerous complications, some even potentially fatal, such as myocardial infarction, atherosclerosis, thromboembolism, shock and stroke.Methods: A cross-sectional prospective study was conducted with the help of a pre-validated questionnaire during the course of 6 months in the medicine outpatient department and the inpatient department (wards) at a tertiary care hospital, Navi Mumbai in 200 hypertensive patients to calculate the correlation of the sociodemographic factors with adherence by the chi-squared test.Results: The overall percentage of adherence to antihypertensive medication was 34.8%. It was the highest (72.1%) in the younger age group, i.e., below 50 years. It was observed that as the age increases, the adherence to treatment decreases. Adherence rates were significantly higher among females and those individuals who had never attended school. Among the employed, 70.3% were adherent to their treatment and among the unemployed, 64.4% were adherent. The percentage of adherence was lower in alcohol consumers (9.5%) as compared to nonusers (76% and 32%, respectively).Conclusions: The clinician advising anti-hypertensive therapy should provide thorough counselling and stress on the issues created due to poor medication adherence as hypertension can be associated with severe outcomes. Treatments should be given in accordance with each patient’s lifestyles in mind such that they may continue taking their medications till the completion of their therapy.

scholarly journals Sleep Quality among Medical Students of a Tertiary Care Hospital: A Descriptive Cross-sectional Study

2020 ◽  
Vol 58 (222) ◽  
Author(s):  
Nabin Sundas ◽  
Saransh Ghimire ◽  
Suzit Bhusal ◽  
Rakshya Pandey ◽  
Krishna Rana ◽  
...  
Keyword(s):  
Academic Performance ◽  
Medical Students ◽  
Sleep Quality ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Poor Sleep ◽  
Care Hospital ◽  
Poor Sleep Quality ◽  
Cross Sectional

Introduction: Medical students are under constant stress due to demanding academic load, fearof exam failure and hectic schedules. These factors can lead to poor sleep quality among medicalstudents. Sleep quality of medical students not only determine their academic performance but isalso important in determining long term effect on cognitive, psychosocial, behavioural as well asphysical health of individuals. Although there are not enough recent studies to assess sleep qualityof students, it is necessary to evaluate the condition of sleep among students. This study aims to findout the prevalence of poor sleep quality among medical students. Methods: This descriptive cross-sectional was conducted among undergraduate medical studentsof Kathmandu Medical College from October to November 2019 after taking ethical clearance fromInstitutional Review Committee of a tertiary care hospital before collecting data from participants.Subjects were recruited by simple random sampling from students of first, second, third and finalyears and were asked to fill the self-reported questionnaires, using Pittsburgh Sleep Quality Index.Descriptive statistical analysis was done using Statistical Software for Social Sciences version 24. Results: Out of 217 selected medical students, 96 (44.23%) of students have poor sleep quality withprevalence among male and female students as 41 (39.8%) and 55 (48.2%) respectively. The meanduration of sleep among students was 6.7±1.6 hours. Conclusions: Significant numbers of medical students have poor sleep quality which may affecttheir academic performance and may have long term impact on their health. Efforts must be directedtowards educating about the sleep hygiene as well as proper time management skills.

APPICATION OF GALECTIN3 , A NOVEL IMMUNOSTAIN, IN PROSTATIC CARCINOMA TO ASSESS ITS PATTERN OF EXPRESSION AND FUTURE POTENTIAL- CONDUCTED AS A TOOL OF MINI RESEARCH PROJECT

2021 ◽  
pp. 33-36
Author(s):  
Sarbashis Hota ◽  
Tushar Kanti Das ◽  
Sneha Sneha ◽  
Anish Kumar Rakshit ◽  
Krishnendu Bikas Bag
Keyword(s):  
Prostate Cancer ◽  
Tumour Progression ◽  
Tertiary Care ◽  
Developed Countries ◽  
Tumour Microenvironment ◽  
Care Hospital ◽  
Grade Group ◽  
Cross Sectional ◽  
Thin Sections ◽  
Positive Expression

Carcinoma of prostate is the commonest type of cancer found in males of developed countries and is responsible for large number of cancer related deaths and signicant morbidity .Gleason’s grade and PSA level play pivotal role in decision making in the management of patients with prostate cancer. By modulating various aspects of tumour progression, Galectin 3 is emerging as a potential guardian of tumour microenvironment and studies indicate that it has important regulatory role in pathogenesis and progression of prostate cancer. An observational cross sectional study was undertaken in the department of pathology of a tertiary care hospital in East India, of 6 months duration. Twenty nine samples diagnosed as acinar adenocarcinoma of prostate were taken by systematic random sampling as per the inclusion-exclusion criteria from the received specimens in the department and immuno-histochemical examination was done on the selected samples using monoclonal antibody against Galectin3 after obtaining thin sections from formalin xed parafn embedded blocks and retrieval of antigen. The data was interpreted by light microscopy using a semi-quantitative method with respect to prexed parameters and statistical analysis was done using SPSS version 25. Based on the prexed cut off, 20.7% of total cases have shown positive expression of galectin3. Mainly the tumours with lower Gleason’s grade have shown positive expression of this marker (62.5% of grade group 1 and 16.6% of grade group 2). None of the cases belonging to grade group 3, 4 or 5 have shown even minimal positivity. Positive expression of galectin3 appeared to decrease with progression of Gleason’s grade and this association was found to be statistically signicant. However, no signicant association has been found between expression of this marker and percentage of the positive cores or the degree of maximum linear positivity.

scholarly journals Prevalence of Adolescent Pregnancy in A Tertiary Care Hospital

2019 ◽  
Vol 57 (218) ◽  
Author(s):  
Shanti Sunuwar Subedi ◽  
Sajjan Sharma ◽  
Munjal Yadav
Keyword(s):  
Adolescent Pregnancy ◽  
Teenage Pregnancy ◽  
Tertiary Care Hospital ◽  
Social Stigma ◽  
Tertiary Care ◽  
Sampling Technique ◽  
Educational Status ◽  
Developed Countries ◽  
Care Hospital ◽  
Cross Sectional

Introduction: WHO defines adolescent pregnancy as any pregnancy from a girl who is 10-19 years of age, the age being defined as her age at the time the baby is born. Globally, adolescent birth rate is 44 per 1000 women aged 15-19 years whereas 33 per 1000 in South East Asian region. The main objective of the study is to find the prevalence of adolescent pregnancy in a tertiary care hospital. Methods: A descriptive cross-sectional study was conducted in Department of Obstetrics and Gynecology, Nobel Medical College and Teaching Hospital, Biratnagar over a period of six months from 1st January 2018 to 30th June 2018. Using the convenient sampling technique, 2688 samples were studied and the descriptive statistical analysis was done. Results: The prevalence of teenage pregnancy was found to be among 143 (5.3%) [5.3%±0.85% at 95% Confidence Interval]. Maximum adolescents of 95 (66.4%) presented at gestational age between 37 to 40 weeks. Regarding contraception, only 2 (1.4%) of teenage mothers had used Injectable Depo Provera. Conclusions: Adolescent pregnancy in developed countries is usually outside of marriage and carries a social stigma but in the context of developing countries it usually happens within marriage and half of them are planned reflecting educational status and contraception knowledge. Effective interventions need to be developed like strict enforcement of laws prohibiting teenage marriage.

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