Effect of CO2 flow rate, co-solvent and pressure behavior to yield by supercritical CO2 extraction of Mariposa Christia Vespertilionis leaves

Cardamom is plant of the Zingiberaceae family. It has been used for the treatment of many diseases such as migraine, bronchitis, stomach and intestinal disorders. Cardamom contains triterpenes, resins, starch and fatty compounds. Phytosterols (stigmasterol, campesterol and β-sitosterol) are a group steroid alcohol in plants. They are used food, medicine and cosmetic industry. They are protective effects against some types of cancer too. Phytosterols are found in the vegetable oil such as the spindle, corn and soybean oil. This paper deals with the maximum oil and β-sitosterol yield were investigated by means of the supercritical CO2 extraction of cardamom. The effect of operating parameters as temperature, pressure and CO2 flow rate were investigated on oil yield. The amount of β-sitosterol was analyzed by Gas Chromatography-Mass Spectrometry (GC-MS) at optimized conditions. The optimized conditions were recorded as temperature of 40oC, pressure of 200 bar and CO2 flow rate of 4 L/min. The maximum oil yield and amount of β-sitosterol were found as 74.83 mg oil/g seed and 4.73 mg β-sitosterol/g seed cardamom under these conditions.

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A comparative study of solvent and supercritical CO2 extraction of Simarouba gluaca seed oil

Grasas y Aceites ◽

10.3989/gya.0214171 ◽

2017 ◽

Vol 68 (3) ◽

pp. 205

Author(s):

B. Anjaneyulu ◽

S. Satyannarayana ◽

Sanjit Kanjilal ◽

V. Siddaiah ◽

K. N. Prasanna Rani

Keyword(s):

Flow Rate ◽

Supercritical Co2 ◽

Seed Oil ◽

Phosphorus Content ◽

Chemical Properties ◽

Supercritical Co2 Extraction ◽

Physico Chemical ◽

Phosphorous Content ◽

Co2 Flow ◽

Carbon Dioxide Co2

In the present study, the supercritical carbon dioxide (CO2) extraction of oil from Simarouba gluaca seeds was carried out at varying conditions of pressure (300–500 bar), temperature (50–70 °C) and CO2 flow rate (10–30 g·min-1). The extraction condition for maximum oil yield was obtained at 500 bar pressure, 70 °C and at 30 g·min-1 flow rate of CO2. The extracted oil was analyzed thoroughly for physico-chemical properties and compared with those of conventional solvent extracted oil. An interesting observation is a significant reduction in the phosphorus content of the oil (8.4 mg·kg-1) extracted using supercritical CO2 compared to the phosphorous content of the solvent extracted oil (97 mg·kg-1). Moreover, the content of total tocopherols in supercritically extracted oil (135.6 mg·kg-1) was found to be higher than the solvent extracted oil (111 mg·kg-1). The rest of the physico-chemical properties of the two differently extracted oils matched well with each other. The results indicated the possible benefits of supercritical CO2 extraction over solvent extraction of Simarouba gluaca seed oil.

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Pecan Oil Recovery and Composition as Affected by Temperature, Pressure, and Supercritical CO2 Flow Rate

Journal of Food Science ◽

10.1111/j.1365-2621.1997.tb15452.x ◽

1997 ◽

Vol 62 (4) ◽

pp. 762-766 ◽

Cited By ~ 12

Author(s):

W.S. ALEXANDER ◽

G.H. BRUSEWITZ ◽

N.O. MANESS

Keyword(s):

Flow Rate ◽

Oil Recovery ◽

Supercritical Co2 ◽

Co2 Flow

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Extraction of Aucubin from Seeds of Eucommia ulmoides Oliv. Using Supercritical Carbon Dioxide

Journal of AOAC International ◽

10.1093/jaoac/92.1.103 ◽

2009 ◽

Vol 92 (1) ◽

pp. 103-110 ◽

Cited By ~ 8

Author(s):

Hui Li ◽

Jiangyu Hu ◽

Hui Ouyang ◽

Yanan Li ◽

Hui Shi ◽

...

Keyword(s):

Supercritical Co2 ◽

Soxhlet Extraction ◽

Extraction Methods ◽

High Yield ◽

Eucommia Ulmoides ◽

Extraction Temperature ◽

Supercritical Co2 Extraction ◽

Extraction And Separation ◽

Soxhlet Method ◽

Co2 Flow

Abstract Supercritical CO2 was used as solvent for the extraction of aucubin from the seeds of Eucommia ulmoides Oliv. The co-solvent composition was tested and extraction conditions were optimized. Results showed that the best co-solvent was a waterethanol mixture (1 + 3, v/v), and the highest yield was obtained when the extraction was performed under 26 MPa at extraction and separation temperatures of 55 and 30C for 120 min, using 6 mL co-solvent/g material at a CO2 flow rate of 20 L/h. In a comparison of the supercritical CO2 and Soxhlet extraction methods, the Soxhlet method needed 3 h to extract 10 g material, whereas the supercritical CO2 extraction technique needed only 2 h to extract 100 g material, thus showing a high extraction capability. The supercritical CO2 extraction produced a higher yield, with a lower cost for the extraction. Owing to the advantages of low extraction temperature, high yield, and ease of separating the product from the solvent, supercritical CO2 extraction is likely to be developed into an ideal technique for the extraction of aucubin, a compound with thermal instability, from the seeds of this plant.

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Numerical Investigation on Maldistribution of Supercritical CO2 Flow Inside Printed Circuit Heat Exchanger

Volume 6A: Thermal-Hydraulics and Safety Analyses ◽

10.1115/icone26-81266 ◽

2018 ◽

Author(s):

Xiao Qi ◽

Ke Hanbing ◽

Zhao Zhenxing ◽

Li Yongquan ◽

Liao Mengran

Keyword(s):

Heat Transfer ◽

Heat Exchanger ◽

Flow Rate ◽

Heat Exchangers ◽

Supercritical Co2 ◽

Brayton Cycle ◽

Printed Circuit ◽

Co2 Flow ◽

Thermal Physical Properties ◽

Flow Nonuniformity

Supercritical CO2 (S-CO2) Brayton cycle has been identified as a promising power conversion method for the next generation of nuclear reactors due to its high efficiency and compactness. The heat exchanger is one of the most important components for S-CO2 Brayton cycle, and the printed circuit heat exchanger (PCHE) is supposed to be one of the promising candidates for the heat exchangers in S-CO2 Brayton cycle. It should be noted that the fluid maldistribution would induce heat transfer deterioration, especially for heat exchangers with micro- or mini-scale channels like PCHE. The thermal-physical properties of S-CO2 change violently during the heat transfer process, which makes the flow inside PCHE more complex. In this paper, the distribution of S-CO2 flow inside PCHE would be studied by 2-D CFD simulations. For the working fluids with constant properties, the flow nonuniformity increases with the mass flow rate. For the working fluid with S-CO2, the thermal-physical properties change significantly with temperature, and there exist a minimum value in the flow nonuniformity-mass flow rate curves (1.64 × 105 ≤ Rein ≤ 1.31 × 106). Insertion of baffles at manifolds could significantly improve the flow distribution uniformity and reduce the pressure drop. And it has been found that insertion of baffles at the collecting manifold has better performance compared with that at the distributing manifold or both.

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Supercritical CO2 Extraction of Organic Solvents from Flunisolide and Fluticasone Propionate

Pharmaceutics ◽

10.3390/pharmaceutics13050612 ◽

2021 ◽

Vol 13 (5) ◽

pp. 612

Author(s):

Lucia Baldino ◽

Mariarosa Scognamiglio ◽

Ernesto Reverchon

Keyword(s):

Fluticasone Propionate ◽

Organic Solvents ◽

Supercritical Co2 ◽

Supercritical Co2 Extraction ◽

Solvent Residues ◽

Co2 Flow ◽

Final Residue ◽

Work Class ◽

Residual Organic Solvents ◽

Co2 Density

In this work, Class 2 and Class 3 solvents contained in two corticosteroids, flunisolide (Fluni) and fluticasone propionate (Fluti), were reduced to a few ppm by supercritical CO2 extraction. The process was carried out at pressures from 80 to 200 bar, temperatures of 40 °C and 80 °C, and at a fixed CO2 flow rate of 0.7 kg/h. The results demonstrated that CO2 density is the key parameter influencing the extraction kinetics and the solvent final residue. In particular, in the range investigated, optimal pressure and temperature conditions for the extraction of residual organic solvents were found working at 200 bar and 40 °C, which corresponds to a CO2 density of 0.840 g/cm3. Operating in this way, total organic solvent residues were reduced from 13,671 ppm and 326 ppm to 12 ppm and 10 ppm for Fluni and Fluti, respectively.

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Supercritical CO2 Extraction And Optimization of Total Phenols From Strawberry tree (Arbutus unedo L.) Fruits: A Comparative Study

Planta Medica ◽

10.1055/s-0031-1282646 ◽

2011 ◽

Vol 77 (12) ◽

Author(s):

Ş Akay ◽

I Alpak ◽

Ö Yeşil Çeliktaş

Keyword(s):

Comparative Study ◽

Supercritical Co2 ◽

Total Phenols ◽

Supercritical Co2 Extraction ◽

Arbutus Unedo ◽

Strawberry Tree

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Optimized Supercritical CO2 Extraction Enhances the Recovery of Valuable Lipophilic Antioxidants and Other Constituents from Dual-Purpose Hop (Humulus lupulus L.) Variety Ella

Antioxidants ◽

10.3390/antiox10060918 ◽

2021 ◽

Vol 10 (6) ◽

pp. 918

Author(s):

Nóra Emilia Nagybákay ◽

Michail Syrpas ◽

Vaiva Vilimaitė ◽

Laura Tamkutė ◽

Audrius Pukalskas ◽

...

Keyword(s):

Supercritical Co2 ◽

Antioxidant Properties ◽

Extraction Yield ◽

Biologically Active ◽

High Yield ◽

Acid Extraction ◽

Supercritical Co2 Extraction ◽

Bioactive Constituents ◽

Total Extract

The article presents the optimization of supercritical CO2 extraction (SFE-CO2) parameters using response surface methodology (RSM) with central composite design (CCD) in order to produce single variety hop (cv. Ella) extracts with high yield and strong in vitro antioxidant properties. Optimized SFE-CO2 (37 MPa, 43 °C, 80 min) yielded 26.3 g/100 g pellets of lipophilic fraction. This extract was rich in biologically active α- and β-bitter acids (522.8 and 345.0 mg/g extract, respectively), and exerted 1481 mg TE/g extract in vitro oxygen radical absorbance capacity (ORAC). Up to ~3-fold higher extraction yield, antioxidant recovery (389.8 mg TE/g pellets) and exhaustive bitter acid extraction (228.4 mg/g pellets) were achieved under the significantly shorter time compared to the commercially used one-stage SFE-CO2 at 10–15 MPa and 40 °C. Total carotenoid and chlorophyll content was negligible, amounting to <0.04% of the total extract mass. Fruity, herbal, spicy and woody odor of extracts could be attributed to the major identified volatiles, namely β-pinene, β-myrcene, β-humulene, α-humulene, α-selinene and methyl-4-decenoate. Rich in valuable bioactive constituents and flavor compounds, cv. Ella hop SFE-CO2 extracts could find multipurpose applications in food, pharmaceutical, nutraceutical and cosmetics industries.

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