scholarly journals The exacerbation of Ebola outbreaks by conflict in the Democratic Republic of the Congo

2019 ◽  
Vol 116 (48) ◽  
pp. 24366-24372 ◽  
Author(s):  
Chad R. Wells ◽  
Abhishek Pandey ◽  
Martial L. Ndeffo Mbah ◽  
Bernard-A. Gaüzère ◽  
Denis Malvy ◽  
...  
Keyword(s):  
Disease Transmission ◽  
Democratic Republic ◽  
Population Level ◽  
Model Framework ◽  
Public Health Response ◽  
Local Conditions ◽  
Health Response ◽  
Republic Of The Congo ◽  
And Control ◽  
The Impact

The interplay between civil unrest and disease transmission is not well understood. Violence targeting healthcare workers and Ebola treatment centers in the Democratic Republic of the Congo (DRC) has been thwarting the case isolation, treatment, and vaccination efforts. The extent to which conflict impedes public health response and contributes to incidence has not previously been evaluated. We construct a timeline of conflict events throughout the course of the epidemic and provide an ethnographic appraisal of the local conditions that preceded and followed conflict events. Informed by temporal incidence and conflict data as well as the ethnographic evidence, we developed a model of Ebola transmission and control to assess the impact of conflict on the epidemic in the eastern DRC from April 30, 2018, to June 23, 2019. We found that both the rapidity of case isolation and the population-level effectiveness of vaccination varied notably as a result of preceding unrest and subsequent impact of conflict events. Furthermore, conflict events were found to reverse an otherwise declining phase of the epidemic trajectory. Our model framework can be extended to other infectious diseases in the same and other regions of the world experiencing conflict and violence.

scholarly journals The impact of surveillance and control on highly pathogenic avian inuenza outbreaks in poultry in Dhaka division, Bangladesh

2017 ◽  
Author(s):  
Edward M. Hill ◽  
Thomas House ◽  
Madhur S. Dhingra ◽  
Wantanee Kalpravidh ◽  
Subhash Morzaria ◽  
...  
Keyword(s):  
Disease Transmission ◽  
Control Measure ◽  
Control Policy ◽  
Transmission Model ◽  
Model Framework ◽  
Highly Pathogenic ◽  
Management Actions ◽  
H5n1 Influenza ◽  
And Control ◽  
The Impact

AbstractIn Bangladesh, the poultry industry is an economically and socially important sector, but it is persistently threatened by the effects of H5N1 highly pathogenic avian influenza. Thus, identifying the optimal control policy in response to an emerging disease outbreak is a key challenge for policy-makers. To inform this aim, a common approach is to carry out simulation studies comparing plausible strategies, while accounting for known capacity restrictions. In this study we perform simulations of a previously developed H5N1 influenza transmission model framework, fitted to two separate historical outbreaks, to assess specific control objectives related to the burden or duration of H5N1 outbreaks among poultry farms in the Dhaka division of Bangladesh. In particular, we explore the optimal implementation of ring culling, ring vaccination and active surveillance measures when presuming disease transmission predominately occurs from premises-to-premises, versus a setting requiring the inclusion of external factors. Additionally, we determine the sensitivity of the management actions under consideration to differing levels of capacity constraints and outbreaks with disparate transmission dynamics. While we find that reactive culling and vaccination policies should pay close attention to these factors to ensure intervention targeting is optimised, across multiple settings the top performing control action amongst those under consideration were targeted proactive surveillance schemes. Our findings may advise the type of control measure, plus its intensity, that could potentially be applied in the event of a developing outbreak of H5N1 amongst originally H5N1 virus-free commercially-reared poultry in the Dhaka division of Bangladesh.

scholarly journals The impact ofInfection Prevention and control (IPC) bundle implementationon IPC compliance during the Ebola virus outbreak in Mbandaka/Democratic Republic of the Congo: a before and after design

BMJ Open ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. e029717 ◽  
Author(s):  
Kevin Ousman ◽  
Landry Kabego ◽  
Ambrose Talisuna ◽  
Janet Diaz ◽  
John Mbuyi ◽  
...  
Keyword(s):  
Prevention And Control ◽  
Ebola Virus ◽  
Democratic Republic ◽  
P Value ◽  
Before And After ◽  
Republic Of The Congo ◽  
The Mean ◽  
And Control ◽  
The Impact

ObjectivesTo assess the impact of refresher training of healthcare workers (HCWs) in infection prevention and control (IPC), ensuring consistent adequate supplies and availability of IPC kits and carrying out weekly monitoring of IPC performance in healthcare facilities (HCFs)DesignThis was a before and after comparison studySettingsThis study was conducted from June to July 2018 during an Ebola virus disease (EVD) outbreak in Equateur Province in the Democratic Republic of the Congo (DRC).Participants48 HCFsInterventionsHCWs capacity building in basic IPC, IPC kit donation and IPC mentoring.Primary outcome measuresIPC scoreResults48 HCFs were evaluated and 878 HCWs were trained, of whom 437 were women and 441 were men. The mean IPC score at baseline was modestly higher in hospitals (8%) compared with medical centres (4%) and health centres (4%), respectively. The mean IPC score at follow-up significantly increased to 50% in hospitals, 39% in medical centres and 36% in health centres (p value<0.001). The aggregate mean IPC score at baseline for all HCFs, combined was 4.41% and at follow-up it was 39.51% with a mean difference of 35.08% (p-value<0.001).ConclusionsImplementation of HCW capacity building in IPC, IPC kit donation to HCF and mentoring in IPC improved IPC compliance during the ninth EVD outbreak in the DRC.

Conflicts in Biafra, Katanga and Cabinda as a result of the geopolitical legacy of colonialism

2020 ◽  
Vol 2020 (10-3) ◽  
pp. 238-246
Author(s):  
Olga Dzhenchakova
Keyword(s):  
Democratic Republic ◽  
Economic Factor ◽  
Colonial Period ◽  
Sub Saharan Africa ◽  
Negative Consequences ◽  
Post Colonial ◽  
Republic Of The Congo ◽  
Sub Saharan ◽  
The Republic ◽  
The Impact

The article considers the impact of the colonial past of some countries in sub-Saharan Africa and its effect on their development during the post-colonial period. The negative consequences of the geopolitical legacy of colonialism are shown on the example of three countries: Nigeria, the Democratic Republic of the Congo and the Republic of Angola, expressed in the emergence of conflicts in these countries based on ethno-cultural, religious and socio-economic contradictions. At the same time, the focus is made on the economic factor and the consequences of the consumer policy of the former metropolises pursuing their mercantile interests were mixed.

scholarly journals Effect of COVID-19 on childhood Mycoplasma pneumoniae infection in Chengdu, China

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ying Zhang ◽  
Yijie Huang ◽  
Tao Ai ◽  
Jun Luo ◽  
Hanmin Liu
Keyword(s):  
Public Health ◽  
Mycoplasma Pneumoniae ◽  
Close Contact ◽  
Serum Antibody ◽  
Pathogen Transmission ◽  
Western China ◽  
Public Health Response ◽  
The Public ◽  
Health Response ◽  
The Impact

Abstract Background Following the outbreak of the COVID-19 pandemic, a change in the incidence and transmission of respiratory pathogens was observed. Here, we retrospectively analyzed the impact of COVID-19 on the epidemiologic characteristics of Mycoplasma pneumoniae infection among children in Chengdu, one of the largest cities of western China. Method M. pneumoniae infection was diagnosed in 33,345 pediatric patients with respiratory symptoms at the Chengdu Women’s & Children’s Central Hospital between January 2017 and December 2020, based on a serum antibody titer of ≥1:160 measured by the passive agglutination assay. Differences in infection rates were examined by sex, age, and temporal distribution. Results Two epidemic outbreaks occurred between October-December 2017 and April-December 2019, and two infection peaks were detected in the second and fourth quarters of 2017, 2018, and 2019. Due to the public health response to COVID-19, the number of positive M. pneumoniae cases significantly decreased in the second quarter of 2020. The number of M. pneumoniae infection among children aged 3–6 years was higher than that in other age groups. Conclusions Preschool children are more susceptible to M. pneumoniae infection and close contact appears to be the predominant factor favoring pathogen transmission. The public health response to COVID-19 can effectively control the transmission of M. pneumoniae.

scholarly journals The impact of support programmes for survivors of sexual violence: micro-level evidence from eastern Democratic Republic of the Congo

2018 ◽  
Vol 34 (3) ◽  
pp. 201-223 ◽  
Author(s):  
Christine Amisi ◽  
Rosalie Biaba Apassa ◽  
Aline Cikara ◽  
Gudrun Østby ◽  
Ragnhild Nordås ◽  
...  
Keyword(s):  
Sexual Violence ◽  
Democratic Republic ◽  
Republic Of The Congo ◽  
Micro Level ◽  
Support Programmes ◽  
The Impact

scholarly journals Operation “Artemis”: The First Autonomous EU-led Operation

2015 ◽  
Vol 14 (1) ◽  
pp. 121-132
Author(s):  
János Tomolya
Keyword(s):  
United Nations ◽  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
European Security ◽  
Republic Of Congo ◽  
Autonomous Operation ◽  
Republic Of The Congo ◽  
Operational Constraints ◽  
And Control ◽  
The Eu

In June 2003, the EU launched Operation “Artemis”, its first military mission outside Europe and independent of NATO, to the Democratic Republic of Congo. While it ultimately received an EU badge, its origin, command and control were French. The objective of Operation “Artemis” was to contribute to the stabilisation of the security conditions in Bunia, capital of Ituri, to improve the humanitarian situation, and to ensure the protection of displaced persons in the refugee camps in Bunia. Its mandate was to provide a short-term interim force for three months until the transition to the reinforced United Nations Mission in the Democratic Republic of Congo (MONUC – Mission de l’Organisation des Nations Unies en République Démocratique du Congo; English: United Nations Organization Stabilization Mission in the Democratic Republic of the Congo). Although the EU can be said to have passed the first “test” of the European Security and Defence Policy (ESDP) mechanisms for the conduct of an autonomous operation, this test was a limited one. Operational constraints were caused by inadequate strategic lift capabilities and the lack of a strategic reserve.

scholarly journals Vaccinating Adolescents and Children Significantly Reduces COVID-19 Morbidity and Mortality across All Ages: A Popula-Tion-Based Modeling Study Using the UK as an Example

Vaccines ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 1180
Author(s):  
Tinevimbo Shiri ◽  
Marc Evans ◽  
Carla A. Talarico ◽  
Angharad R. Morgan ◽  
Maaz Mussad ◽  
...  
Keyword(s):  
Disease Transmission ◽  
Age Groups ◽  
Population Level ◽  
Vital Role ◽  
Morbidity And Mortality ◽  
Transmission Model ◽  
Base Case ◽  
Global Public Health ◽  
The Uk ◽  
The Impact

Debate persists around the risk–benefit balance of vaccinating adolescents and children against COVID-19. Central to this debate is quantifying the contribution of adolescents and children to the transmission of SARS-CoV-2, and the potential impact of vaccinating these age groups. In this study, we present a novel SEIR mathematical disease transmission model that quantifies the impact of different vaccination strategies on population-level SARS-CoV-2 infections and clinical outcomes. The model employs both age- and time-dependent social mixing patterns to capture the impact of changes in restrictions. The model was used to assess the impact of vaccinating adolescents and children on the natural history of the COVID-19 pandemic across all age groups, using the UK as an example. The base case model demonstrates significant increases in COVID-19 disease burden in the UK following a relaxation of restrictions, if vaccines are limited to those ≥18 years and vulnerable adolescents (≥12 years). Including adolescents and children in the vaccination program could reduce overall COVID-related mortality by 57%, and reduce cases of long COVID by 75%. This study demonstrates that vaccinating adolescents and children has the potential to play a vital role in reducing SARS-CoV-2 infections, and subsequent COVID-19 morbidity and mortality, across all ages. Our results have major global public health implications and provide valuable information to inform a potential pandemic exit strategy.

Environmental Degradation, Tropical Diseases, and Economic Development

2021 ◽  
Author(s):  
John Luke Gallup
Keyword(s):  
Climate Change ◽  
Economic Development ◽  
Environmental Degradation ◽  
Global Climate ◽  
Life Cycles ◽  
Tropical Diseases ◽  
Local Conditions ◽  
Climate Conditions ◽  
And Control ◽  
The Impact

It’s complicated. Tropical diseases have unusually intricate life cycles because most of them involve not only a human host and a pathogen, but also a vector host. The diseases are predominantly tropical due to their sensitivity to local ecology, usually due to the vector organism. The differences between the tropical diseases mean that they respond to environmental degradation in various ways that depend on local conditions. Urbanization and water pollution tend to limit malaria, but deforestation and dams can exacerbate malaria and schistosomiasis. Global climate change, the largest environmental change, will likely extend the range of tropical climate conditions to higher elevations and near the limits of the tropics, spreading some diseases, but will make other areas too dry or hot for the vectors. Nonetheless, the geographical range of tropical diseases will be primarily determined by public health efforts more than climate. Early predictions that malaria will spread widely because of climate change were flawed, and control efforts will probably cause it to diminish further. The impact of human disease on economic development is hard to pin down with confidence. It may be substantial, or it may be misattributed to other influences. A mechanism by which tropical disease may have large development consequences is its deleterious effects on the cognitive development of infants, which makes them less productive throughout their lives.

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