Obesity and Metabolic Syndrome in a Psychiatric Rehabilitation Service

2007 ◽  
Vol 41 (7) ◽  
pp. 606-610 ◽  
Author(s):  
Srinivasan Tirupati ◽  
Ling-Ern Chua
Keyword(s):  
Metabolic Syndrome ◽  
Metabolic Disorders ◽  
Psychotic Disorders ◽  
Psychiatric Rehabilitation ◽  
International Diabetes Federation ◽  
Rehabilitation Program ◽  
Management Program ◽  
Rehabilitation Service ◽  
Rehabilitation Outcomes ◽  
Prevalence Of Obesity

Objective: People with schizophrenia and bipolar disorders suffer from increased rates of obesity and metabolic syndrome. Metabolic disorders add to the burden of disease and affect treatment and rehabilitation outcomes. This study aimed to study the prevalence of obesity and metabolic syndrome in people with chronic psychotic disorders in a psychiatric rehabilitation setting. Method: All patients in the psychiatry rehabilitation program were assessed for obesity and metabolic syndrome using the definition of International Diabetes Federation (2005) was conducted as part of clinical protocol recently introduced into practice. Results: A total of 221 patients were assessed. The prevalence of obesity was 59% and metabolic syndrome 68%. Metabolic syndrome was more frequent in patients receiving polypharmacy with multiple antipsychotics and mood stabilisers. Rates of nontreatment for metabolic disorders ranged from 30% to 88%. Conclusions: The rates of obesity and metabolic syndrome in patients with chronic severe mental disorders on antipsychotic drug treatment were 2 to 3 times that in the general population. A majority of them were untreated. Detection, monitoring and appropriate treatment of obesity and metabolic disorders should be a component of an assertive care management program to reduce morbidity and mortality and improve rehabilitation outcomes.

scholarly journals Factors associated to functioning and health in relation to home rehabilitation in Sweden: a non-randomized pre-post intervention study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Anette Johansson ◽  
Marie Ernsth Bravell ◽  
Eleonor I. Fransson ◽  
Sofi Fristedt
Keyword(s):  
Repeated Measures ◽  
Linear Models ◽  
Medical Condition ◽  
Rehabilitation Program ◽  
Community Dwelling ◽  
Rehabilitation Service ◽  
Post Intervention ◽  
Factors Associated ◽  
Rehabilitation Outcomes ◽  
Self Rated Health

Abstract Background Home rehabilitation is a growing rehabilitation service in many countries, but scientific knowledge of its components and outcomes is still limited. The aim of this study was to investigate; 1) which changes in functioning and self-rated health could be identified in relation to a home rehabilitation program in a population of community-dwelling citizens, and 2) how socio-demographic factors, health conditions and home rehabilitation interventions were associated to change in functioning and self-rated health after the home rehabilitation program. Method The sample consisted of participants in a municipal home rehabilitation project in Sweden and consisted of 165 community-dwelling citizens. General Linear Models (ANOVA repeated measures) was used for identifying changes in rehabilitation outcomes. Logistic regressions analysis was used to investigate associations between rehabilitation outcomes and potential factors associated to outcome. Result Overall improvements in functioning and self-rated health were found after the home rehabilitation program. Higher frequencies of training sessions with occupational therapists, length of home rehabilitation, and orthopaedic conditions of upper extremities and spine as the main health condition, were associated with rehabilitation outcomes. Conclusion The result indicates that the duration of home rehabilitation interventions and intensity of occupational therapy, as well as the main medical condition may have an impact on the outcomes of home rehabilitation and needs to be considered when planning such programs. However, more research is needed to guide practice and policymaking.

scholarly journals Prevalence of different components of the metabolic syndrome in type 2 diabetics attending tertiary care hospital in Himalayan region

2017 ◽  
Vol 5 (12) ◽  
pp. 5232
Author(s):  
Vikram Singh ◽  
Mridu Singh ◽  
Anil Joshi ◽  
Chitra Joshi
Keyword(s):  
Metabolic Syndrome ◽  
Tertiary Care ◽  
International Diabetes Federation ◽  
Diabetic Patients ◽  
Care Hospital ◽  
The Metabolic Syndrome ◽  
Type 2 Diabetics ◽  
Hilly Region ◽  
Prevalence Of Obesity

Background: There are enormous studies on various aspect of Diabetes and Metabolic syndrome, majority of studies are on urban population, few in rural area but very few for the population living in far flung hilly region of Himalaya. The aim was to find the prevalence of different components of metabolic syndrome in Type 2 diabetics living in the hills of Himalaya and to find correlation with obesity.Methods: All the Type 2 Diabetic patients age 35 years and above attending the inpatients and out patient’s department of V. C. S. G. G. M. C and RI Srinagar, Uttarakhand from October 2012 to March 2013 were enrolled and were evaluated for metabolic syndrome by IDF (International Diabetes Federation) criteria.Results: 128 diabetics were enrolled (76 males and 52 females), the prevalence of obesity in patients of type 2 diabetics was 45.3%. There was poor correlation between obesity and type 2 diabetes (correlation coefficient 0.08) The prevalence of metabolic syndrome was 40.6 % and high percentage (62%) had all five components of the syndrome.Conclusions: The prevalence of obesity and Metabolic syndrome is relatively lower in Type 2 Diabetics of Shivalik range of Himalaya (Uttarakhand).

scholarly journals Effectiveness of a Day Rehabilitation Program in Improving Functional Outcome and Reducing Mortality and Readmission of Elderly Patients With Fragility Hip Fractures

2018 ◽  
Vol 9 ◽  
pp. 215145931875935 ◽  
Author(s):  
Tak Man Wong ◽  
Frankie K. L. Leung ◽  
Tak Wing Lau ◽  
Christian Fang ◽  
Felix H. W. Chan ◽  
...  
Keyword(s):  
Hip Fracture ◽  
Elderly Patients ◽  
Demographic Data ◽  
Rehabilitation Program ◽  
Cognitive Outcomes ◽  
Rehabilitation Service ◽  
World Population ◽  
Rehabilitation Outcomes ◽  
Geriatric Hip Fracture ◽  
Elderly Mobility

Introduction: The incidence of hip fracture is projected to increase in the next 25 years as the world population ages. Hip fracture is often associated with subsequent readmission and mortality. Nevertheless, elderly patients often may not achieve the same level of functional ability as prior to their injury. Several studies have shown that close collaboration between orthopedic surgeons and geriatricians can improve such outcomes and Geriatric Day Hospital (GDH) is one of the examples of collaboration to improve such outcomes. The aim of this descriptive retrospective study is to review the effectiveness of the day rehabilitation program provided by a GDH on functional outcomes, mortality, and readmission rate, among a sample of elderly patients with hip fracture. Methods: The medical records of patients from January 1, 2009, to December 31, 2012, were collected and evaluated. Demographic data of the patients and Charlson Comorbidity Index were collected. The Barthel Index, Elderly Mobility Scale, and Mini-Mental State Examination were measured on admission and at discharge of the patients to evaluate both physical and cognitive functions. Results: The results showed that the majority of patients benefited from rehabilitation in the GDH. The 12-month mortality rate of patients taking full-course rehabilitation in the GDH was improved. The age of patient was the most important factor influencing the rehabilitation outcomes. Gender was the only risk factor for 12-month mortality and 6-month readmission. Discussion: Since patients were selected to attend GDH, there was a bias during the selection of patients. Furthermore, it was difficult to compare patients attended GDH with patients who did not because outcomes of the latter were difficult to be recorded. Conclusions: Our study shows that postoperative geriatric hip fracture patients definitely can benefit from rehabilitation service offered by GDH in terms of functional and cognitive outcomes.

scholarly journals EFFECT OF LEPR AND GR GENE POLYMORPHISMS ON HEALTH STATUS OF MOTHERS WITH METABOLIC DISORDERS AND THEIR NEWBORNS

2020 ◽  
Vol 20 (3) ◽  
pp. 20-25
Author(s):  
V.I. Pokhуlko ◽  
Yu.I. Cherniavska ◽  
S.M. Tsvirenko ◽  
Z.I. Rossokha ◽  
Yu.Yu. Klymchiuk
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Gene Polymorphisms ◽  
Metabolic Disorders ◽  
Cross Sectional Study ◽  
Control Group ◽  
Genetic Determinants ◽  
Cross Sectional ◽  
Prevalence Of Obesity

The high prevalence of obesity and metabolic syndrome throughout the world over the past two decades provided the grounds to the WHO to consider overweight as a non-infectious pandemic. Among the factors that negatively affect the metabolism, result in metabolic disorders and obesity there are genetic, prenatal, diet-related, somatic, psychogenic and others. Analysis of LEPR and GR gene polymorphisms among mothers and their newborns can be an important component in the prediction of metabolic disorders and obesity. The aim of this study was to analyze the presence of clinical and genetic determinants of metabolic syndrome in mothers and their newborns. Materials and methods. A cross-sectional study of 42 pairs of mothers and newborns was performed; we analyzed their anthropometric, clinical and laboratory parameters and, in particular, 2 types of genetic polymorphisms (LEPR rs1137101 and GR, BClI polymorphism). The main group consisted of 15 mother-child pairs, where the woman was clinically obese (body mass index more than 30), the comparison group included 27 mother-child pairs, where the women were overweight (body mass index more than 25). Results. Obese mothers were significantly more likely to have a miscarriage (p = 0.01). Children from obese mothers had significantly higher percentiles of birth weight compared to the control group (60.9 ± 7.7 and 49.75 ± 4.5, respectively, p = 0.05). The GG genotype of the GR gene was associated with more common indications for hospitalization (p = 0.012), rapid delivery (p = 0.01), umbilical cord entanglement around the neck of the foetus (p = 0.012). Among the children- carriers of the GG BclI genotype GR, cardio-metabolic disorders detected by the auscultation of the heart (arrhythmia, functional noise) were found out as significantly more frequent (p = 0.003). Conclusion. The study did not find the associations between LEPR and GR gene polymorphism in obese mothers and the development of overweight in their children, but the study revealed an adverse effect of polymorphic variants on obstetric and gynaecological status of mothers, labour and adaptation of infants in the early neonatal period.

scholarly journals An approach to the etiology of metabolic syndrome

2013 ◽  
pp. 57-63 ◽  
Author(s):  
Angélica M Muñoz ◽  
Gabriel Bedoya ◽  
Claudia Velásquez
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Signal Transduction ◽  
Intracellular Signaling ◽  
Metabolic Disorders ◽  
Biochemical Responses ◽  
The World ◽  
Prevalence Of Obesity ◽  
Genetic Mechanisms

Increased prevalence of obesity in the world, especially accumulation of abnormal amounts of visceral fat predisposes to insulina resistance, which is the central role of metabolic syndrome (MS). Obesity can deregulate the intracellular signaling of insulina due to the production of inflammatory substances, chemo attractant proteins, adipokines and molecules that trigger hormonal mediator potentials for destabilization of signal transduction, leading to metabolic disorders such as hyperglycemia, hypertension, and dyslipidemia. The complexity of the MS and of the genetic mechanisms involved in its etiology derives from the combination of variants on genes involved and environmental factors that predispose it. The purpose of this paper is to review the effects of obesity in molecular and biochemical responses that trigger insulin resistance and its relation to some candidate genes and the ancestral component of the population.

The Use of Berberine in Diabetes and Metabolic Syndrome: Two Sides of the Same Coin. A Bibliometric Analysis

2021 ◽  
Vol 17 ◽  
Author(s):  
Vittoria Infantino ◽  
Antonella Riva ◽  
Giovanna Petrangolini ◽  
Pietro Allegrini ◽  
Simone Perna ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Bibliometric Analysis ◽  
Metabolic Disorders ◽  
Human Subjects ◽  
Diabetes Type 2 ◽  
The Metabolic Syndrome ◽  
Prevalence Of Obesity ◽  
Two Sides

: The increased prevalence of obesity, metabolic syndrome and type 2 diabetes has prompted scientists to look for new active and safe molecules that may help the prevention of metabolic disorders: hyperglycemia, insulin-resistance, dyslipidemia. Berberine is an alkaloid compound derived from plants, and it is largely used in traditional chinese medicine. The aim of this study is to investigate in SCOPUS and Web of Science (WOS) databases how the scientists focused on the use of berberine against metabolic disorders, in human subjects. We carried A bibliometric analysis of scientific literature and performed 2 searches: 1) “Berberine” AND “Diabetes” AND “Diabetes Type 2”, 2) “Berberine” AND “Metabolic Syndrome”, both in ARTICLE (Title/Abstract/Keyword) with a time limitation of 1 January 2000 through 31 December 2018, with the filter on “HUMAN” AND/OR “HUMANS”. The research sorted out 500 papers, finding about 300 (60 %) in the first search definition, and 200 (40 %) in the second. The refined research sorted out 46 papers regarding the use of berberine in diabetes, and 40 articles on the use of the alkaloid compound in the metabolic Syndrome. For both topics, we found increasing interest between 2008 and 2009, with citation trends in a constant crescendo in the overall period studied. These findings underlined that berberine is a safe and interesting botanical compound, especially against chronic-metabolic disorder that affects billions of people globally, and emphasized that scientists are interested in searching for long-term therapies that show no major adverse effects.

scholarly journals A Sustainable Approach to the Metabolic Syndrome in Children and Its Economic Burden

2020 ◽  
Vol 17 (6) ◽  
pp. 1891
Author(s):  
Manuel Vaquero Alvarez ◽  
Pilar Aparicio-Martinez ◽  
Francisco Javier Fonseca Pozo ◽  
Joaquín Valle Alonso ◽  
Isabel María Blancas Sánchez ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Economic Burden ◽  
International Diabetes Federation ◽  
Research Strategy ◽  
Non Invasive ◽  
The Metabolic Syndrome ◽  
Prevalence Of Obesity ◽  
Invasive Method ◽  
The Cost ◽  
Web Platform

The prevalence of obesity continues to grow, resulting in metabolic syndrome and increasing economic burden for health systems. The objectives were to measure the ability of the NIM-MetS test, previously used in the adults, for the early and sustainable detection of the Metabolic Syndrome (MetS) in children and adolescents. Moreover, to determine the economic burden of the children with MetS. Furthermore, finally, to use and implement the NIM-MetS test, via a self-created online software, as a new method to determine the risk of MetS in children. The method used was an observational study using different instruments (NIM-MetS test, International Diabetes Federation (IDF), or Cook) and measures (body mass index). Additionally, the economic burden was estimated via a research strategy in different databases, e.g., PubMed, to identify previous papers. The results (N = 265 children, age from 10–12) showed that 23.1% had obesity and 7.2% hypertension. The prevalence of MetS using the NIM-Mets was 5.7, and the cost of these children was approximate 618,253,99 euros. Finally, a model was obtained and later implemented in a web platform via simulation. The NIM-MetS obtained is a non-invasive method for the diagnosis of risk of MetS in children.

scholarly journals Low prevalence of the metabolic syndrome but high occurrence of various metabolic disorders in Chinese women with polycystic ovary syndrome

2009 ◽  
Vol 161 (3) ◽  
pp. 411-418 ◽  
Author(s):  
Ren-min Ni ◽  
Yaqin Mo ◽  
Xiaoli Chen ◽  
Junmin Zhong ◽  
Wen Liu ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Polycystic Ovary Syndrome ◽  
Metabolic Disorders ◽  
Chinese Women ◽  
Polycystic Ovary ◽  
International Diabetes Federation ◽  
Ovary Syndrome ◽  
High Occurrence ◽  
The Metabolic Syndrome ◽  
Low Prevalence

ObjectiveVariations in the prevalence of metabolic syndrome (MetS) among women with polycystic ovary syndrome (PCOS) in different races were reported. We sought to report this prevalence and its components in Chinese women with PCOS and compared these characteristics with healthy controls.DesignAnthropometric measurements and biochemical parameters were evaluated in 578 PCOS patients diagnosed by the Rotterdam criteria and 281 age- and body mass index (BMI)-matched controls. International Diabetes Federation criteria for MetS were used.ResultsThe prevalence of MetS was 16.8% in this study, and 60.7% of patients displayed at least one component of MetS. Among the patients, the rates of dyslipidemia, impaired fasting glucose, and elevated blood pressure were 41.6, 19.8, and 16.1% respectively; the rates of these corresponding components in age- and BMI-matched controls were 14.6, 5.3, and 5.7% respectively. In PCOS patients, the prevalence of MetS was 0.0, 3.9, 20.2, and 51.1% for four different BMI groups respectively; the prevalence of MetS was 7.3, 14.9, 24.2, and 42.4% in the four age groups respectively. Nearly 90% of patients diagnosed with MetS belonged to overweight and obese groups. BMI and age rather than free testosterone, free androgen index, fasting insulin, or sex hormone-binding globulin were included in formulation for predicting MetS according to multivariable logistic regression.ConclusionsLow prevalence of MetS but high occurrence of various metabolic disorders was found in women with PCOS compared with age- and BMI-matched controls in this study. BMI and age appeared to contribute more to developing MetS than other parameters associated with insulin resistance or hyperandrogenism.

scholarly journals A study on the prevalence of obesity and metabolic syndrome among students of a medical college

2017 ◽  
Vol 5 (6) ◽  
pp. 2331
Author(s):  
Srinivas G. N. S. V Kandula ◽  
Sasi Sekhar T. V. D. ◽  
Shruti Kongara ◽  
Santhosh Kumar Arepalli
Keyword(s):  
Metabolic Syndrome ◽  
Medical Students ◽  
Waist Circumference ◽  
International Diabetes Federation ◽  
Strong Relationship ◽  
Cross Sectional Study ◽  
Individual Risk ◽  
Junk Food ◽  
Cross Sectional ◽  
Prevalence Of Obesity

Background: Obesity is emerging as a serious problem throughout the world. The overall life expectancy is significantly shortened and the quality of life decreased in those who are excessively overweight. Metabolic syndrome (MetS) is characterized by a constellation of individual risk factors of cardiovascular disease. Central obesity is a key feature of this syndrome, reflecting the fact that the syndrome’s prevalence is driven by strong relationship between waist circumference and increasing obesity. Awareness about MetS in medical students is the need of the hour.Methods: This cross-sectional study was conducted at Dr. PSIMS and RF, Chinnoutpalli, Andhra Pradesh, India involving 400 medical students. A pre-tested questionnaire, measurement of blood pressure, fasting glucose level, fasting lipid profile, anthropometric variables such as height, weight, waist circumference and hip circumference were taken. Metabolic syndrome was defined based on the International Diabetes Federation criteria. Data was processed using SPSS version 16. T-test, chi-square test, fisher’s exact test, anova and odd’s ratio were used for statistical analysis.Results: 59% of the study population was female. The prevalence of obesity was 4%, with majority being males (81.25%) The MetS prevalence as per the International diabetes federation (IDF) criteria was 6% (n=24). The prevalence of MetS in males was 12.19% (n=20) and in females 1.69%. (n=4). The risk of developing metabolic syndrome is high among those who smoke, consume alcohol, consume junk food and sleep for longer durations.Conclusions: The prevalence of metabolic syndrome is 6%. A significant association is established between life style habits like smoking, alcohol consumption, junk food consumption, sleep duration and MetS.

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