The Influence of Environmental Temperature on the Response of the Skin to Local Pressure: The Impact of Aging and Diabetes

2009 ◽  
Vol 11 (12) ◽  
pp. 791-798 ◽  
Author(s):  
Katie McLellan ◽  
Jerrold S. Petrofsky ◽  
Grenith Zimmerman ◽  
Everett Lohman ◽  
Michelle Prowse ◽  
...  
Keyword(s):  
Environmental Temperature ◽  
Local Pressure ◽  
The Impact

scholarly journals A Mathematical Model for Swallowing of Concentrated Fluids in Oesophagus

2011 ◽  
Vol 8 (3-4) ◽  
pp. 309-321 ◽  
Author(s):  
S. K. Pandey ◽  
Dharmendra Tripathi
Keyword(s):  
Mathematical Model ◽  
Flow Rate ◽  
Plug Flow ◽  
Flow Region ◽  
Mechanical Efficiency ◽  
Casson Fluid ◽  
Local Pressure ◽  
Integral Number ◽  
Tomato Puree ◽  
The Impact

This model investigates particularly the impact of an integral and a non-integral number of waves on the swallowing of food stuff such as jelly, tomato puree, soup, concentrated fruits juices and honey transported peristaltically through the oesophagus. The fluid is considered as a Casson fluid. Emphasis is on the study of the dependence of local pressure distribution on space and time. Mechanical efficiency, reflux limit and trapping are also discussed. The effect of Casson fluid vis-à-vis Newtonian fluid is investigated analytically and numerically too. The result is physically interpreted as that the oesophagus makes more efforts to swallow fluids with higher concentration. It is observed that the pressure is uniformly distributed when an integral number of waves is there in the oesophagus; but it is non-uniform when a non-integral number of waves is present therein. It is further observed that as the plug flow region widens, the pressure difference increases, which indicates that the averaged flow rate will reduce for a Casson fluid. It is also concluded that Casson fluids are more prone to reflux.

A New Cavitation-Induced-Momentum-Defect (CIMD) Correction Approach to Track Cavitation Events

2007 ◽  
Author(s):  
Vedanth Srinivasan ◽  
Abraham J. Salazar ◽  
Kozo Saito
Keyword(s):  
Liquid Phase ◽  
Transport Equation ◽  
Vapor Phase ◽  
Incompressible Flows ◽  
Vapor Transport ◽  
Source Terms ◽  
Local Pressure ◽  
Cloud Cavitation ◽  
Tracking Model ◽  
The Impact

A new unsteady cavitation event tracking model is developed for predicting vapor dynamics occurring in multi-dimensional incompressible flows. The procedure solves incompressible Navier-Stokes equations for the liquid phase with an additional vapor transport equation for the vapor phase. The model tracks regions of liquid vaporization and applies compressibility effects to compute the local variation in speed of sound using the Homogeneous Equilibrium Model (HEM) assumptions. The variation of local cell density as a function of local pressure is used to construct the source term in the vapor fraction transport equation. The novel Cavitation-Induced-Momentum-Defect (CIMD) correction methodology developed in this study serves to account for cavitation inception and collapse events as relevant momentum source terms in the liquid phase momentum equations. Effects of vapor phase accumulation and diffusion are incorporated by detailed relaxation models. A modified RNG K-ε model, including the effects of compressibility in the vapor regions, is employed for modeling turbulence effects. Turbulent kinetic energy and dissipation contributions from the vapor regions are integrated with the liquid phase turbulence using relevant source terms. Numerical simulations are carried out using a Finite Volume methodology available within the framework of commercial CFD software code Fluent v.6.2. Simulation results are in qualitative agreement with experiments for unsteady cloud cavitation behavior in planar nozzle flows. Multitude of mechanisms such as formation of vortex cavities, vapor cluster shedding and coalescence, cavity pinch off are sharply captured by the supplemented vapor transport equation. Our results concur with previously established theories concerning sheet and cloud cavitation such as the re-entrant jet motion, cavity closure and the impact of adverse pressure gradients on cavitation dynamics.

scholarly journals Differential responsiveness of glabrous and non-glabrous skin to local transmural pressure elevations; the impact of 5 weeks of iterative local pressure loading

2021 ◽  
Author(s):  
Michail E. Keramidas ◽  
Roger Kölegård ◽  
Patrik Sundblad ◽  
Håkan Sköldefors ◽  
Ola Eiken
Keyword(s):  
Transmural Pressure ◽  
Glabrous Skin ◽  
Local Pressure ◽  
Wide Range ◽  
Forearm Skin ◽  
Differential Responsiveness ◽  
Pressure Resistance ◽  
The Impact ◽  
Pressure Perturbations

We examined the in vivo pressure-flow relationship in human cutaneous vessels during acute and repeated elevations of local transmural pressure. In 10 healthy men, red blood cell flux was monitored simultaneously on the non-glabrous skin of the forearm and the glabrous skin of a finger during a vascular pressure provocation, wherein the blood vessels of an arm were exposed to a wide range of stepwise increasing distending pressures. Forearm skin blood flux was relatively stable at slight and moderate elevations of distending pressure, whereas it increased ~3-4-fold at the highest levels (P = 0.004). Finger blood flux on the contrary, dropped promptly and consistently throughout the provocation (P < 0.001). Eight of the subjects repeated the provocation trial after a 5-week pressure-training regimen, during which the vasculature in one arm was exposed intermittently (40 min, 3 times･week-1) to increased transmural pressure (from +65 mmHg week-1 to +105 mmHg week-5). The training regimen diminished the pressure-induced increase in forearm blood flux by ~34% (P = 0.02), whereas it inhibited the reduction in finger blood flux (P < 0.001) in response to slight and moderate distending pressure elevations. The present findings demonstrate that, during local pressure perturbations, the cutaneous autoregulatory function is accentuated in glabrous compared to in the non-glabrous skin regions. Prolonged intermittent regional exposures to augmented intravascular pressure blunt the responsiveness of the glabrous skin, but enhance arteriolar pressure resistance in the non-glabrous skin.

scholarly journals The impact of channel fin width on electrical characteristics of Si-FinFET

2022 ◽  
Vol 12 (1) ◽  
pp. 201
Author(s):  
Yousif Atalla ◽  
Yasir Hashim ◽  
Abdul Nasir Abd. Ghafar
Keyword(s):  
Threshold Voltage ◽  
Field Effect ◽  
Field Effect Transistor ◽  
Environmental Temperature ◽  
Simulation Tool ◽  
Electrical Characteristics ◽  
Working Temperature ◽  
Effect Transistor ◽  
The Impact ◽  
The Ideal

<span>This paper studies the impact of fin width of channel on temperature and electrical characteristics of fin field-effect transistor (FinFET). The simulation tool multi-gate field effect transistor (MuGFET) has been used to examine the FinFET characteristics. Transfer characteristics with various temperatures and channel fin width (W<sub>F</sub>=5, 10, 20, 40, and 80 nm) are at first simulated in this study. The results show that the increasing of environmental temperature tends to increase threshold voltage, while the subthreshold swing (SS) and drain-induced barrier lowering (DIBL) rise with rising working temperature. Also, the threshold voltage decreases with increasing channel fin width of transistor, while the SS and DIBL increase with increasing channel fin width of transistor, at minimum channel fin width, the SS is very near to the best and ideal then its value grows and going far from the ideal value with increasing channel fin width. So, according to these conditions, the minimum value as possible of fin width is the preferable one for FinFET with better electrical characteristics.</span>

​Impact of Extreme Hot Environmental Temperature Period on Marker Enzymes of Carbohydrate Metabolism in Non-descript Sheep from Arid Tracts of Rajasthan

2021 ◽  
Author(s):  
Anandita Srivastava ◽  
Nalini Kataria
Keyword(s):  
Carbohydrate Metabolism ◽  
Environmental Temperature ◽  
Age Groups ◽  
Extreme Temperature ◽  
Mean Value ◽  
Marker Enzymes ◽  
Mean Values ◽  
The Mean ◽  
The Impact ◽  
Enzymes Of Carbohydrate Metabolism

Background: The present investigation was envisaged to find out the impact of extreme hot environmental temperature period (ETP) on marker enzymes of carbohydrate metabolism in male and female non-descript sheep of various age groups i.e. 4 to 13 months from arid tracts of Rajasthan. Glucose-6-phosphate dehydrogenase (G-6-PDH) and malate dehydrogenase (MDH) marker enzymes of carbohydrate metabolism were considered for study. Methods: During the period October 2016-June 2017 blood samples were collected to harvest sera for spectrophotometric method from 240 healthy animals selected from private slaughter house during moderate and extreme hot environmental temperature periods (ETPs). The mean values of markers attained during moderate ETP were reckoned as the control. It was 10.00 ± 0.10 UL-1 and 42.00±1.00 respectively. Conclusion: The mean value of MDH was significantly (p≤0.05) higher while G-6-PDH significantly (p≤0.05) lowers during extreme hot temperature in comparison to moderate period. Therefore, it could be concluded that variations in enzyme markers were associated with changes in environmental temperatures. Probably ETP were able to produce a profound effect on carbohydrate metabolism in sheep. Therfore it can be suggested that during the period of extreme temperature balanced ration must be provided to the animal along with proper management to decrease the severity of temperature impact.

scholarly journals Effects of 7°C environmental temperature acclimation during a 3-week training period

2020 ◽  
Vol 128 (4) ◽  
pp. 768-777
Author(s):  
Robert Shute ◽  
Katherine Marshall ◽  
Megan Opichka ◽  
Halee Schnitzler ◽  
Brent Ruby ◽  
...  
Keyword(s):  
Room Temperature ◽  
Environmental Temperature ◽  
Cellular Signaling ◽  
Temperature Acclimation ◽  
Peroxisome Proliferator ◽  
Peroxisome Proliferator Activated Receptor ◽  
Training Adaptations ◽  
Before And After ◽  
The Impact ◽  
Environmental Temperatures

Cold environmental temperatures during exercise and recovery alter the acute response to cellular signaling and training adaptations. Approximately 3 wk is required for cold temperature acclimation to occur. To determine the impact of cold environmental temperature on training adaptations, fitness measurements, and aerobic performance, two groups of 12 untrained male subjects completed 1 h of cycling in 16 temperature acclimation sessions in either a 7°C or 20°C environmental temperature. Fitness assessments before and after acclimation occurred at standard room temperature. Muscle biopsies were taken from the vastus lateralis muscle before and after training to assess molecular markers related to mitochondrial development. Peroxisome proliferator-activated receptor-γ coactivator 1α ( PGC-1α) mRNA was higher in 7°C than in 20°C in response to acute exercise before training ( P = 0.012) but not after training ( P = 0.813). PGC-1α mRNA was lower after training ( P < 0.001). BNIP3 was lower after training in the 7°C than in the 20°C group ( P = 0.017) but not before training ( P = 0.549). No other differences occurred between temperature groups in VEGF, ERRα, NRF1, NRF2, TFAM, PINK1, Parkin, or BNIP3L mRNAs ( P > 0.05). PGC-1α protein and mtDNA were not different before training, after training, or between temperatures ( P > 0.05). Cycling power increased during the daily training ( P < 0.001) but was not different between temperatures ( P = 0.169). V̇o2peak increased with training ( P < 0.001) but was not different between temperature groups ( P = 0.460). These data indicate that a 3-wk period of acclimation/training in cold environmental temperatures alters PGC-1α gene expression acutely but this difference is not manifested in a greater increase in V̇o2peak and is dissipated as acclimation takes place. NEW & NOTEWORTHY This study examines the adaptive response of cellular signaling during exercise in cold environmental temperatures. We demonstrate that peroxisome proliferator-activated receptor-γ coactivator 1α mRNA is different between cold and room temperature environments before training but after training this difference no longer exists. This initial difference in transcriptional response between temperatures does not lead to differences in performance measures or increases in protein or mitochondria.

scholarly journals Computational and Experimental Study of Convection in a Vanadium Redox Flow Battery Strip Cell Architecture

Energies ◽  
2020 ◽  
Vol 13 (18) ◽  
pp. 4767
Author(s):  
Tugrul Y. Ertugrul ◽  
Michael. C. Daugherty ◽  
Jacob R. Houser ◽  
Douglas S. Aaron ◽  
Matthew M. Mench
Keyword(s):  
Pressure Drop ◽  
Current Distribution ◽  
Vanadium Redox Flow Battery ◽  
Local Concentration ◽  
Total Current ◽  
Local Pressure ◽  
Large Current ◽  
Cell Architecture ◽  
Wide Range ◽  
The Impact

The impact of convection on electrochemical performance, performance distribution, and local pressure drop is investigated via simple strip cell architecture, a cell with a single straight channel. Various channel depths (0.25, 0.5, 1, 2.5 mm) and flow rates (10–50 mL min−1 cm−2) are employed to induce a wide range of electrolyte velocities within the channel and electrode. Computational flow simulation is utilized to assess velocity and pressure distributions; experimentally measured in situ current distribution is quantified for the cell. Although the total current in the cell is directly proportional to electrolyte velocity in the electrode, there is no correlation detected between electrolyte velocity in the channel and the total current. It is found that the maximum achievable current is limited by diffusion mass transport resistance between the liquid electrolyte and the electrode surfaces at the pore level. Low electrolyte velocity induces large current gradients from inlet to outlet; conversely, high electrolyte velocity exhibits relatively uniform current distribution down the channel. Large current gradients are attributed to local concentration depletion in the electrode since the velocity distribution down the channel is uniform. Shallow channel configurations are observed to successfully compromise between convective flow in the electrode and the overall pressure drop.

scholarly journals The impact of environmental temperature deception on perceived exertion during fixed-intensity exercise in the heat in trained-cyclists

2018 ◽  
Vol 194 ◽  
pp. 333-340
Author(s):  
D.N. Borg ◽  
I.B. Stewart ◽  
J.T. Costello ◽  
C.C. Drovandi ◽  
G.M. Minett
Keyword(s):  
Perceived Exertion ◽  
Environmental Temperature ◽  
The Impact

Active Control of Unsteady Cavitating Flows in Turbomachinery

2019 ◽  
Author(s):  
Maria Grazia De Giorgi ◽  
Antonio Ficarella ◽  
Donato Fontanarosa
Keyword(s):  
Active Control ◽  
Synthetic Jet ◽  
Hydrodynamic Performance ◽  
Transfer Model ◽  
Thick Sheet ◽  
Dimensionless Frequency ◽  
Pulsation Frequency ◽  
Local Pressure ◽  
Vapor Cavity ◽  
The Impact

Abstract A preliminary 2D numerical investigation of the active control of unsteady cavitation by means of one single synthetic jet actuator (SJA) is presented. The SJA has been applied to hinder the intrinsic instabilities of a cloud cavitating flow of water around a NACA 0015 hydrofoil with an angle of attack of 8° and ambient conditions. It has been placed inside the inception region at a distance of 16% of the chord from the leading edge. Concerning the numerical approach, a Eulerian homogeneous mixture/mass transfer model has been used, in combination with an extended Schnerr-Sauer cavitation model and a Volume of Fluid (VOF) interface tracking method. The synthetic jet has been modeled by means of a user-defined velocity boundary conditions based on a sinusoidal waveform. A sensitivity analysis has been first performed in order to evaluate the influence of the main control parameters, namely the momentum coefficient Cμ, the dimensionless frequency F+ and the jet angle αjet. By combining the cavitating vapor content and the impact on the hydrodynamic performance, the best performing SJA configuration has been retrieved. Then, a deeper analysis of the vapor cavity dynamics and the vorticity field has been conducted in order to understand the modification of the main flow produced by the synthetic jet. The best SJA configuration was observed at Cμ = 0.0002, F+ = 0.309 and αjet = 90°, which led to a reduction of both the average vapor content and the average torsional load in the measure of 34.6% and 17.8% respectively. A reduction of the average pulsation frequency of the pressure upstream confirmed the beneficial effect of the SJA. The analysis of the coupled dynamics between vapor cavity-vorticity and their POD-based modal structures highlighted that the benefit of the SJA lies on preventing the growth of a thick sheet cavity which tends to cause the development of the highly cavitating cloud dynamics after the cavity breakup. This is mainly due to an additional vorticity close to the hydrofoil surface just downstream the SJA, as well as a local pressure modification close the SJA during the blowing stroke.

Sign in / Sign up

Export Citation Format

Share Document