scholarly journals Efficacy of standard- vs reduced-dose insulin for treatment of hyperkalemia: A quasi-experiment

2021 ◽  
Author(s):  
Sara Catherine Pearson ◽  
Kristin O’Connor ◽  
Kimberly Keller ◽  
T J Hodge ◽  
Ross Nesbit
Keyword(s):  
Glucose Level ◽  
Standard Dose ◽  
Additional Treatment ◽  
Treatment Pathway ◽  
Reduced Dose ◽  
Significant Difference ◽  
Before And After ◽  
Quasi Experimental ◽  
Stage Renal Disease ◽  
The Impact

Abstract Disclaimer In an effort to expedite the publication of articles related to the COVID-19 pandemic, AJHP is posting these manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. Purpose Hyperkalemia more commonly affects patients with a glomerular filtration rate of less than 60 mL/min. Using intravenous (IV) insulin to shift potassium intracellularly may cause hypoglycemia, requiring additional treatment or longer hospitalization. Literature on insulin dosing in this context is limited, with one previous study indicating that 5 units of IV insulin might be as effective and result in less hypoglycemia than the standard dose of 10 units of IV insulin. The hyperkalemia treatment pathway at our institution was revised in May 2018 to include a reduced-dose option (5 units of insulin) for patients with end-stage renal disease. This study aimed to compare the prevalence of hypoglycemia between patients who received standard-dose vs reduced-dose IV insulin. Methods This single-center, retrospective, quasi-experimental study evaluated the impact of revision of the hyperkalemia treatment pathway by assessing rates of hypoglycemia during the 6 months before and after implementation of the revised pathway. The primary endpoint was prevalence of hypoglycemia, defined as a blood glucose level of less than or equal to 70 mg/dL. Results There was no statistically significant difference in the occurrence of hypoglycemia when comparing the pre- and postimplementation groups (36 [17.7%] patients vs 34 [18.7%] patients; P = 0.7924). The postimplementation group had a statistically significant lower reduction in potassium levels after treatment than the preimplementation group (mean [interquartile range], –0.9 [–1.3, –0.5] mEq/L vs –0.6 [–1.2, –0.2] mEq/L; P = 0.0095). Baseline potassium levels were similar between the groups. Conclusion Administration of reduced-dose IV insulin for treatment of hyperkalemia was significantly less effective in lowering serum potassium levels and did not decrease prevalence of hypoglycemia. When accounting for potential confounders, the only variable that was associated with hypoglycemia was pretreatment glucose level.

scholarly journals The Impact of Education on Mother’s Knowledge for Stunting Prevention Through Moringa Oleifera in Kuan Noel Village, Fatumnasi District, South Central Timor Regency

2020 ◽  
Vol 8 (3) ◽  
pp. 206
Author(s):  
IRLIN FALDE RITI
Keyword(s):  
Treatment Group ◽  
Moringa Oleifera ◽  
Sampling Technique ◽  
Control Group ◽  
South Central ◽  
Significant Difference ◽  
Before And After ◽  
Quasi Experimental ◽  
The Impact ◽  
Educational Aspect

<p align="center"><strong>ABSTRAK</strong></p><p><strong>Background:</strong> One of nutritious problems susceptibly encountred in the world nowadays is kid’s stunting. Stunting is a failure of growth condition and cronical nutritious problems caused by poor nutritious supply because of improper meal provisions in long term growth consumptions. Stunting could be primarily prevented by increasing knowledge about stunting prevention through consuming moringa oleifera regularly. <strong>The aim:</strong> This study is intended to know the impact of education on mother’s knowledge for stunting prevention through regular moringa oleifera consumption. <strong>Research Method: </strong>This research applied a quasi experimental design by generating non equivalent control group which complied two groups; 30 subjects (mothers) were considered as treatment group; whereas, other 30 subjects (mothers) were taken as control group. Thus sampling technique applied was consecutive sampling. <strong>Results:</strong> The study showed that there was a significant impact on education score before and after intervention effects towards the treatment group (p=0,000); whereas there was no significant difference on the control group (p=0,184). The statistical analysis applied independent sample t-test which showed if educational aspect significantly impacted on the increase of mother’s knowledge (p=0,000). <strong>Conclusion:</strong> Educational aspect impacted on mother’s knowledge for stunting prevention through moringa oleifera.</p>

scholarly journals EFFECT OF YOGIC EXERCISES AND MEDITATION ON EMOTIONAL WELLNESS AND SPIRITUAL WELLNESS OF WOMEN IN THOOTHUKUDI

2016 ◽  
Vol 4 (9(SE)) ◽  
pp. 63-73
Author(s):  
Thanga Selvam ◽  
Shunmuga SelvaSivaSankari ◽  
A. Nagalakshmi
Keyword(s):  
Personal Health ◽  
Spiritual Wellness ◽  
Health And Wellbeing ◽  
Study Results ◽  
Significant Difference ◽  
Emotional Wellness ◽  
Before And After ◽  
Post Test ◽  
Quasi Experimental ◽  
The Impact

Today, yoga is considered as an alternative exercise approach to obtain personal health and wellbeing. Yoga’s holistic methodology strives to unite one’s body, mind, and spirit; it is a method of exercise mirrored in the physical, mental, and emotional benefits which result. The focus of this paper will highlight on the effect of yogic exercises and meditation on emotional wellness and spiritual wellness among women. The objectives of this study were to find out the level of emotional wellness and spiritual wellness of women before and after treatment and to find out the impact of yogic exercises and meditation on the emotional wellness and spiritual wellness of women. The investigators have adopted quasi-experimental method for this study. Results of this study show that there is significant difference between pretest and post test scores on emotional wellness and spiritual wellness of women before and after the yogic exercises and meditation.

The Impact of Multidisciplinary Rehabilitation on Depressive Symptoms in Hemodialysis Patients

2017 ◽  
Vol 40 (5) ◽  
pp. 738-752
Author(s):  
Shirin Mohammadi-Kalaveh ◽  
Tahereh Toulabi ◽  
Shirin Hasanvand ◽  
Mohammad Gholami ◽  
Fatemeh Ghasemi
Keyword(s):  
Depressive Symptoms ◽  
Depressive Symptom ◽  
Psychological Problem ◽  
Hemodialysis Patients ◽  
Rehabilitation Program ◽  
Multidisciplinary Rehabilitation ◽  
Significant Difference ◽  
Before And After ◽  
Quasi Experimental ◽  
The Impact

Depressive symptom is the most frequent psychological problem reported among chronic kidney disease (CKD) patients being treated by hemodialysis. This article evaluates the effectiveness of multidisciplinary rehabilitation on depressive symptoms in hemodialysis patients and clarifies the role of nurses. This quasi-experimental study was done on 30 patients in the hemodialysis center (educational hospital) in 2013. Eight rehabilitation plans were conducted by nurses. Beck Depression Inventory (BDI) was used before and after intervention. Our data were analyzed using descriptive and inferential statistics. Result of this study shows that there was a significant difference between mean depressive symptom score before (36.4 ± 10.9) and after (10.5 ± 3.1) rehabilitation ( p < .001). It is recommended that rehabilitation program be implemented in all hemodialysis centers with the participation of specialists in different fields.

scholarly journals The Impact of Digital Storytelling on ESL Narrative Writing Skill

2019 ◽  
Author(s):  
Mohd Azmi Zakaria ◽  
Azlina Abdul Aziz
Keyword(s):  
Digital Storytelling ◽  
Structured Interview ◽  
Narrative Writing ◽  
School Students ◽  
Significant Difference ◽  
Writing Skill ◽  
Before And After ◽  
Quasi Experimental ◽  
Tank Test ◽  
The Impact

This paper presents a part of a study on the teaching of narrative writing by incorporating Digital Storytelling. Writing skill is an essential component in mastering English because it incorporates all elements in English. By integrating technology in the learning process, students would be able to improve their writing skill. In Malaysia, students’ performance in examination has declined in recent years since the marks are based mostly on students’ writing. This research aims to know the impact of Digital Storytelling towards Malaysian secondary school students by investigating its impact on content, grammar, vocabulary and overall performance. It also explores students' perception of Digital Storytelling. This quasi-experimental study involved 52 Form four students from a fully-residential school in Melaka who were chosen using convenient sampling as part of the controlled and experimental groups. Data were collected from pre-tests, post-tests and a semi-structured interview. The quantitative data were analyzed using mean analysis, Wilcoxon Signed Tank Test and Independent t-Test while qualitative data were analyzed using thematic analysis. Findings show that there is a significant difference in the score before and after the intervention but there is no significant difference between the score of the experimental group and the controlled group. Participants stated that DS motivates them to write and improves their writing. It is hoped that this study would provide an alternative to teaching narrative writing and adds to the current pool of literature. It is suggested for future researchers to conduct purposive sampling which could yield different results.

scholarly journals The impact of formative assessment on self-regulating learning in university classrooms

2016 ◽  
Vol 4 (1) ◽  
pp. 99 ◽  
Author(s):  
Fisseha Mikre Weldmeskel ◽  
Dreyer Johann Michael
Keyword(s):  
Formative Assessment ◽  
Peer Assessment ◽  
Self Regulation ◽  
Intervention Group ◽  
Self Regulated Learning ◽  
Significant Difference ◽  
Before And After ◽  
Quasi Experimental ◽  
Psychology Course ◽  
The Impact

This study describes the extent of which the use of quality formative assessment on lessons of a course involves the students as self-regulated learners. There is an increased interest among educational researchers to observe improvement of student self-regulation on learning. The predominant use of summative assessment remains a challenge to helping students develop self-regulation skills in learning and assessment. Quality formative assessment includes formative feedback, self-assessment and peer assessment. The study followed a partially mixed sequential research design and applied a quasi-experimental intervention that lasted for six weeks where six educators applied quality formative assessment on lessons of a general psychology course for intervention group students (N=191). The quantitative data were collected by self-regulated learning questionnaire before and after the use of quality formative assessment on lessons. The qualitative data were collected by focus group discussions with the students. The students’ perceptions on self-regulating learning were compared between the intervention (N=191) and the comparison (N=187) group of students. The quantitative analysis used t-test and biserial correlation and proved the presence of statistically significant difference between the two groups in perceiving the self-regulation of learning. Moreover, effect size estimate (Cohen’s d) was used to provide a strong validation on the variation between the two groups for the measure of self-regulating learning. Recommendations were made to promote the use of quality formative assessment aiming at the improvement of student self-regulation on learning and assessment in university classes.

scholarly journals The impact of peer-peer learning and student-lecturer interaction on Biology pre-service teachers’ achievements

2021 ◽  
Vol 16 (2) ◽  
pp. 511-521
Author(s):  
Tafirenyika Mafugu
Keyword(s):  
Online Learning ◽  
Digital Divide ◽  
Peer Interaction ◽  
Control Group ◽  
Tertiary Institutions ◽  
Significant Difference ◽  
Before And After ◽  
Quasi Experimental ◽  
The Impact ◽  
Experimental Group

Because of the outbreak of the COVID-19 pandemic, there was an emergency shift to online learning in tertiary institutions worldwide. Here, I aimed to determine the impact of guided peer-peer interaction on students' achievement. A Biology Achievement Test was used to collect data. I used a quasi-experimental design and analysed the data using the independent sample t-test and one-way ANOVA. A comparison of the experimental group mean marks before and after the lockdown did not reveal significant differences. However, the control group’s mean mark was significantly higher before than during the lockdown period. Before the lockdown, the performance of the experimental group did not show any significant difference with that of the control group. There was a significant difference in performance between the two groups during the lockdown. Lecturer guided interaction had a significant impact while the digital divide did not have a significant impact on students’ performance.   Keywords: online learning; tertiary institutions; peer-peer interaction; digital divide

scholarly journals The impact of clean lifestyle health promotion on the attitude, motivation, and behaviour of village health cadres

2018 ◽  
Vol 31 (3) ◽  
pp. 310
Author(s):  
Tetti Solehati ◽  
Agus Rahmat ◽  
Cecep Eli Kosasih ◽  
Nur Oktavia Hidayati
Keyword(s):  
Health Promotion ◽  
Local Community ◽  
Bivariate Analysis ◽  
Hygiene Behaviour ◽  
Significant Difference ◽  
Before And After ◽  
Post Test ◽  
Quasi Experimental ◽  
The Mean ◽  
The Impact

Pangandaran is a popular tourism destination in West Java, which is annually visited by a high number of foreign and domestic tourists. It has set itself the vision of gaining the title ‘Healthy Village’. However, Pangandaran beach is still fighting the problem of waste, which is easily found along the coast. Thus, disease is mushrooming due to the lack of a Clean Lifestyle (Perilaku Hidup Bersih Sehat/PHBS) and the low awareness of PHBS in the Pangandaran local community. The efforts undertaken to overcome the problem of infectious disease due to the lack of PHBS require great support from various parties such as health service centres and via community participation and the role of cadres, who also manage the Community Health Centres (Pos Pelayanan Terpadu/Posyandu). The study aims to determine the effect of the health promotion of PHBS on the attitude, motivation, and behaviour of the health cadres. The study was quasi-experimental, involving a pre-test and post-test design. The study was conducted in Pangandaran Village, Pangandaran Regency. This research involved the health cadres because they are the closest person to the community and they also run a health program. In addition, they are reliable people when it comes to overcoming health problems in the community. The total population of health cadres in Pangandaran Village amounted to 28 people, via total sampling. The instruments used in this study included a questionnaire, observation sheet, and a checklist. The data analysis used univariate and bivariate analysis. The result showed that the mean score of attitude ranged from 65.11 to 74.71 (p = 0,000), the mean score of motivation was 37.39 to 40.71 (p = 0,000), the mean score of genital hygiene behaviour was 67.96 to 80.61 (p = 0,000) and the mean score of the behaviour of CTPS was significant at 32.25 to 35.71 (p = 0,000). This study found there to be significant difference in the mean attitude, motivation and behaviour of the health cadres before and after the intervention period.

scholarly journals The Effect of Mental Health and Psychosocial Support (MHPS)Training on The Public Awareness of New Habitual Adaptations (NHA): A Pilot Research

2021 ◽  
Vol 16 (3) ◽  
Author(s):  
Susanti Niman ◽  
Habsyah Saparidah Agustina ◽  
Sri Wahyuni ◽  
Niken Yuniar Sari ◽  
Retty Octi Syafrini ◽  
...  
Keyword(s):  
Mental Health ◽  
Psychosocial Support ◽  
Public Awareness ◽  
Health Condition ◽  
P Value ◽  
Increased Risk ◽  
Significant Difference ◽  
Before And After ◽  
Quasi Experimental ◽  
The Impact

<p><strong>Background: </strong>The COVID-19 pandemic has a physical impact and on the mental health condition of the community. The existence of psychological distress due to the Covid 19 pandemic will affect the body's physiological conditions, such as reduced immune system responses and increased risk of infection, and the impact on mental health. The COVID-19 pandemic demands a change in people's behavior. Mental health and psychosocial support training is very important for the community so that the community can actively maintain mental and physical health. The research objective is to identify the effect of DKJPS training on awareness of new adaptation readiness<strong>. Method:</strong> The research was conducted through a quasi-experimental pre-post-test without control on 44 participants in the DKJPS training. <strong>Result: </strong>there is a significant difference between awareness of adaptation new habits before and after training (p-value 0.001). <strong>Conclusion: </strong>Mental health and psychosocial support training conducted in the community can increase public awareness of new adaptation habits independently<strong>.</strong></p>

scholarly journals 1166. Evaluating the Impact of the 2016 Candidemia Guidelines on the Incidence of Ocular Complications of Candidemia

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S609-S609
Author(s):  
Molly Hillenbrand ◽  
Senu Apewokin
Keyword(s):  
Vision Loss ◽  
Bloodstream Infections ◽  
Empiric Therapy ◽  
Prescribing Patterns ◽  
Ocular Complications ◽  
Ocular Penetration ◽  
Significant Difference ◽  
Before And After ◽  
Eye Exams ◽  
The Impact

Abstract Background The incidence of Candida bloodstream infections has risen over the last several decades. Complications of candidemia include endogenous fungal endophthalmitis which can result in devastating outcomes including vision loss. In 2015, the IDSA guidelines were updated to recommend echinocandins as initial therapy for candidemia. Given the poor ocular penetration of echinocandins there has been some concern this change may portend an increased incidence of ocular complications in candidemic patients. We sought to examine whether patients who received empiric echinocandin therapy developed higher rates of ophthalmic complications of candidemia. Methods We identified patients in our healthcare system who had blood cultures positive for Candida species and a completed ophthalmology consult between January 1, 2014 and April 30, 2019. Chi-squared analysis was used to compare antifungal prescribing patterns before and after release of the updated IDSA guidelines. We assessed whether the switch to empiric echinocandin therapy as directed by the guidelines was associated with higher rates of abnormal eye exams. Results 47 patients treated before the guideline change were compared to 57 patients treated after the guideline change. There was no significant difference in age, gender, or comorbid diabetes and hypertension between the groups. Before the guideline change, 24/47 (51%) of patients received eye-penetrating antifungals. This decreased to 21/57 after the updated guideline (37%, p=0.21). The percentage of patients with positive eye exams was nearly equal before and after the updated guidelines, 10/47 (21%) before vs 13/57 (22%) after (p=1). After the guideline change, 7/21 (33%) of the patients treated with penetrating antifungals had positive eye exams vs 6/36 (16%) who received echinocandins (p=0.19). Conclusion Echinocandins are known to have poor ocular penetration yet our data demonstrate no change in the incidence of ophthalmic complications of candidemia after the 2016 guideline endorsed echinocandins as empiric therapy. The prevalence of positive eye exams throughout our study period was 22%, suggesting ongoing utility for these exams. Ongoing investigation is necessary to confirm and further study these findings. Disclosures All Authors: No reported disclosures

A multifaceted stewardship intervention helps curb steroid overprescribing in hospitalized patients with acute exacerbations of COPD

2021 ◽  
Author(s):  
Jennifer L Cole ◽  
Sarah E Smith
Keyword(s):  
Length Of Stay ◽  
Intervention Strategy ◽  
Audit And Feedback ◽  
Face To Face ◽  
Duration Of Therapy ◽  
Significant Difference ◽  
Acute Exacerbations ◽  
Before And After ◽  
Quasi Experimental ◽  
Prospective Audit And Feedback

Abstract Disclaimer In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. Purpose Corticosteroid overprescribing is well documented in real-world practice. There is currently no evidence to guide best practices for steroid stewardship. The aim of this study was to assess the effects of a 3-part stewardship intervention strategy on inpatient steroid prescribing in patients with acute exacerbations of COPD (AECOPD). Summary Investigators implemented a 3-part stewardship initiative consisting of (1) an anonymous survey for providers on steroid prescribing in a simplified case of AECOPD, (2) face-to-face education and review of survey results, and (3) prospective audit and feedback from a clinical pharmacist. This was a quasi-experimental before-and-after study evaluating hospitalized adults diagnosed with AECOPD in two 12-month study periods before (April 2019-March 2020) and after (May 2020-April 2021) implementation. The primary outcome was mean inpatient steroid dosing. Secondary outcomes were duration of therapy, length of stay (LOS), 30-day readmissions, 30-day mortality, and incidence of hyperglycemia. Per power analysis, there were 27 patients per cohort. The interventions resulted in a significant reduction in prednisone equivalents during hospitalization: 118 mg vs 53 mg (P = 0.0003). This decrease was similar in ICU (160 mg vs 61 mg, P = 0.008) and non-ICU (102 mg vs 49 mg, P = 0.004) locations. There was no significant difference in duration of therapy (8 days vs 7 days, P = 0.44), length of stay (3.3 days vs 3.9 days, P = 0.21), 30-day mortality (4% vs 7%, P = 0.55), 30-day readmissions (15% vs 7%, P = 0.39), or rate of hyperglycemia (48% vs 44%, P = 0.78). Conclusion A multifaceted stewardship intervention significantly reduced steroid dosing in hospitalized AECOPD patients. This reduction was not associated with known deleterious effects.

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