scholarly journals Baseline Drinking Patterns in Non-Treatment Seeking Problem Drinkers

2020 ◽  
Vol 56 (1) ◽  
pp. 57-63
Author(s):  
Wave-Ananda Baskerville ◽  
Steven J Nieto ◽  
Diana Ho ◽  
Brandon Towns ◽  
Erica N Grodin ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Heavy Drinking ◽  
Readiness For Change ◽  
Treatment Seeking ◽  
Processes Of Change ◽  
Drinking Patterns ◽  
Problem Drinkers ◽  
Timeline Followback ◽  
Stable Pattern ◽  
Treatment Seekers

Abstract Aims Natural processes of change have been documented in treatment-seekers who begin to reduce their drinking in anticipation of treatment. The study examined whether non-treatment-seeking problem drinkers would engage in drinking reduction in anticipation of participating in a research study. Methods Non-treatment-seeking problem drinkers (n = 935) were culled from five behavioral pharmacology studies. Participants reported on their alcohol use during the past 30 days using the Timeline Followback. Cluster analysis identified distinct groups/clusters based on drinking patterns over the 30-day pre-visit period. The identified clusters were compared on demographic and clinical measures. Results Three distinct clusters were identified (a) heavy-decreasing drinking group (n = 255, 27.27%); (b) a moderate-stable drinking group (n = 353, 37.75%) and (c) low-stable drinking group (n = 327, 34.97%). The three clusters differed significantly on a host of measures including pre-visit drinking (age at first drink, drinking days, drinks per week, drinks per drinking day), alcohol use severity, alcohol craving, readiness for change, depression and anxiety levels. These differences were alcohol dose-dependent such that the heavier drinking group reported the highest levels on all constructs, followed by the moderate group, and the low drinking group last. Conclusions Baseline drinking patterns of non-treatment-seekers were generally stable and pre-visit reductions were only observed among the heavy drinking group. This generally stable pattern stands in contrast to previous reports for treatment-seeking samples. Nevertheless, the heavier drinking group, which is most similar to treatment-seekers, displayed pre-study drinking reduction. Overall, naturalistic processes of change may pose less of a threat to randomization and testing in this population.

scholarly journals 3376 Super Bingers: Traits and Patterns Associated with High-Intensity Drinking

2019 ◽  
Vol 3 (s1) ◽  
pp. 154-155
Author(s):  
James Keoni Morris ◽  
Julia E. Swan ◽  
Josh L. Gowin ◽  
Melanie L. Schwandt ◽  
Nancy Diazgranados ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Binge Drinking ◽  
High Intensity ◽  
Heavy Drinking ◽  
Drinking Patterns ◽  
Timeline Followback ◽  
Level 3 ◽  
Males And Females ◽  
Level 1 ◽  
Level 2

OBJECTIVES/SPECIFIC AIMS: This study attempts to evaluate the drinking patterns and traits of individuals who partake in high intensity drinking, defined as binge drinking at 2 or more times the minimum binge count (4 drinks for females, 5 drinks for males). METHODS/STUDY POPULATION: We analyzed data from non-treatment seeking volunteers enrolled in NIAAA screening protocols. The sample included 706 males and 474 females ranging in age from 18 to 91. Subjects were assigned to one of four groups (Non-Binge, Level 1, Level 2, Level 3) based on the highest binge session reported in their Timeline Followback questionnaire. The criteria for each group were different for males and females based on the current NIAAA definitions of binge drinking. The cutoffs for females were 0-3 drinks for Non-Binge, 4-7 drinks for Level 1, 8-11 drinks for Level 2, and 12+ drinks for Level 3. The male drink cutoffs were 0-4, 5-9, 10-14, and 15+ respectively. We looked at various drinking measures (Timeline Followback, Self-Reported Effects of Alcohol (SRE), Alcohol Use Disorders Identification Test (AUDIT)) and trait measures (UPPS-P Impulsivity Scale, Barratt’s Impulsiveness Scale, Buss Perry Aggression Questionnaire) to identify mean differences between groups. RESULTS/ANTICIPATED RESULTS: There were significant differences in drinking patterns between the groups for both males and females. Number of drinking days, average drinks per drinking day, and number of heavy drinking days all increased as binge level increased. There were also significant differences between groups in males for trait measures. Level 2 and Level 3 bingers scored significantly higher on impulsivity and aggression than the Level 1 and Non-Binge groups. Ongoing analyses are examining differences among binge groups on other measures including SRE and AUDIT. Future analyses will explore potential mechanisms underlying the relationships between trait measures and binge drinking using structural equation modeling. DISCUSSION/SIGNIFICANCE OF IMPACT: This study found significant differences between high-intensity drinkers, or “super bingers”, and lighter binge and non-binge drinkers. Super bingers showed an overall heavier drinking pattern across measures. The elevated aggression, impulsivity, and overall heavy drinking patterns of super bingers suggest a behavioral profile that makes this group in particular at higher risk for developing alcohol use disorder and related problems. These traits and behaviors may also help identify targets for treatment interventions for alcohol use disorder.

scholarly journals 2263

2017 ◽  
Vol 1 (S1) ◽  
pp. 33-33
Author(s):  
Corbin Daniel Ester ◽  
Bethany Stangl ◽  
Aruna Gogineni ◽  
Lauren Blau ◽  
Vatsalya Vatsalya ◽  
...  
Keyword(s):  
Sex Differences ◽  
Family History ◽  
Alcohol Use ◽  
Heavy Drinking ◽  
Alcohol Expectancies ◽  
Subjective Response ◽  
Drinking Patterns ◽  
Risky Drinking ◽  
Alcohol Sensitivity ◽  
Alcohol Hangover

OBJECTIVES/SPECIFIC AIMS: The current study examined hangover following IV alcohol self-administration (IV-ASA) using the Computer-Assisted Infusion System. The goal of the study was to identify predictors of hangover, including drinking history, alcohol sensitivity, family history, expectancies, and sex differences in nondependent drinkers. METHODS/STUDY POPULATION: The study sample included 89 healthy, nondependent drinkers aged 21–45 years. After a screening to exclude any medical illness or psychiatric disorders, participants completed an IV-ASA session. Each session consisted of a 25-minute priming phase, during which participants were prompted to press a button to receive individually standardized alcohol infusions, followed by a 2-hour “open bar” phase, during which they were instructed to recreate a typical drinking experience. Results from the IV-ASA included peak and average BrAC. Drinking patterns were assessed using the Alcohol Use Disorders Identification Test, which provided 3 subscales: consumption (AUDIT-C), dependence (AUDIT-D), and harmful drinking (AUDIT-H). Subjective response to alcohol was measured using the Drug Effects Questionnaire (DEQ). The Alcohol Hangover Scale (AHS) was used to assess hangover for the period between participants’ departure from the study unit and 10 am the next morning. The Alcohol Effects Questionnaire (AEFQ) is a measure which includes 40 true/false statements about how alcohol typically makes respondents feel, and was used to measure alcohol expectancies. RESULTS/ANTICIPATED RESULTS: Results showed that 78% of participants endorsed having at least 1 hangover symptom following IV-ASA. The most commonly reported items were tired, thirsty, headache, and hangover. There was no association between hangover scores and the AUDIT-C or IV-ASA. Because alcohol consumption was not related to hangover symptoms, risky drinking behavior was examined. Results indicated that participants endorsing 4 or more items on the AUDIT-D plus AUDIT-H subscales showed significantly higher average hangover scores. Linear regression analyses indicated that alcohol hangover scores were associated with DEQ items feel, high, and intoxicated. Ongoing analyses are examining additional predictors of hangover including family history, alcohol expectancies, sex differences, and other alcohol sensitivity measures. DISCUSSION/SIGNIFICANCE OF IMPACT: The results indicated that risky drinking patterns and alcohol response measures were positively associated with hangover symptoms in non-dependent drinks, while no correlation between consumption and hangover symptoms were found. Since previous research has shown than greater subjective response is associated with heavy drinking and predictive of alcohol use disorder, it is possible that hangover symptoms is a marker of this relationship. Since the role of hangover in the transition from heavy drinking to disorder still remains unclear, it will be important to characterize this relationship between alcohol sensitivity and hangover as a function of drinking patterns. This understanding may help to prevent this transition from at-risk drinking to alcohol dependent drinking.

Comparing Drinking Patterns in Finland and Ontario (Canada)

2003 ◽  
Vol 30 (3) ◽  
pp. 685-699 ◽  
Author(s):  
John A. Cunningham ◽  
Pia Mäkelä
Keyword(s):  
Alcohol Use ◽  
Binge Drinking ◽  
Heavy Drinking ◽  
Drinking Patterns ◽  
Population Surveys ◽  
The Past ◽  
Males And Females

A comparison is made of drinking patterns in Finland and Ontario (Canada). Respondents in two existing population surveys, the 1996 Joint Nordic Questionnaire and the 1996 Ontario Drug Monitor, were compared on their frequency of alcohol use in the past year, frequency of heavy drinking (6+ on Nordic survey and 5+ in Ontario), and both frequency and typical quantity of beer, wine and liquor consumption in males and females. It appeared that there are fewer nondrinkers and more weekly drinkers in the Finnish sample than in the Ontario sample. Further, both males and females in Ontario consumed 6+ drinks on one occasion more frequently than their Finnish counterparts. However, examination of the patterns of beer, wine and liquor consumption, particularly the distribution of very heavy drinking days (e.g., 12 or more drinks of liquor on one occasion), indicates that there is some evidence for periodic heavy drinking in Finnish males. Contrary to expectations, Canadian and Finnish drinking patterns appeared fairly similar. However, there was some evidence for a higher prevalence of binge drinking by Finnish men as compared with Canadian men.

Patterns of alcohol use 1 year after traumatic brain injury: A population-based, epidemiological study

2005 ◽  
Vol 11 (3) ◽  
pp. 322-330 ◽  
Author(s):  
MICHAEL DAVID HORNER ◽  
PAMELA L. FERGUSON ◽  
ANBESAW W. SELASSIE ◽  
LAWRENCE A. LABBATE ◽  
KATHRYN KNIELE ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
South Carolina ◽  
Brain Injury ◽  
Alcohol Use ◽  
Large Population ◽  
Heavy Drinking ◽  
Population Based ◽  
Drinking Patterns ◽  
Data Set ◽  
Discharge Data

This study delineated patterns of alcohol use 1 year after traumatic brain injury (TBI) in a large, population-based, epidemiological, nonclinical sample, and identified predictors of heavy alcohol use in these individuals. Participants were 1,606 adults identified by review of a South Carolina statewide hospital discharge data set, on the basis of satisfying the Centers for Disease Control case definition of TBI, and were interviewed by telephone 1 year after TBI-related discharge. Alcohol use in the month prior to interview was classified according to categories from the Quantity–Frequency–Variability Index; heavy drinking was defined as nearly daily use with ≥ 5 drinks at least occasionally, or at least three occasions with ≥ 5 drinks. A polychotomous logistic regression with 3 response levels (heavy, moderate, and abstinent/infrequent/light drinking) was used to identify predictors of heavy drinking. Heavy drinking in the month prior to interview was reported by 15.4% of participants, while 14.3% reported moderate drinking and 70.3% reported abstinence or light/infrequent drinking. Risk factors for heavy drinking included male gender, younger age, history of substance abuse prior to TBI, diagnosis of depression since TBI, fair/moderate mental health, and better physical functioning. There was no association between drinking patterns and TBI severity. (JINS, 2005,11, 322–330.)

scholarly journals Interaction of Heavy Drinking Patterns and Depression Severity predicts Efficacy of Quetiapine Fumarate XR in lowering Alcohol Intake in Alcohol Use Disorder Patients

2020 ◽  
Author(s):  
Vatsalya Vatsalya ◽  
Maiying Kong ◽  
Luis M. Marsano ◽  
Zimple D Kurlawala ◽  
Kan V Chandras ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Alcohol Intake ◽  
Rating Scale ◽  
Heavy Drinking ◽  
Depression Symptoms ◽  
Drinking Patterns ◽  
Quetiapine Fumarate ◽  
Heavy Alcohol ◽  
Depression Ratings

Background: Shared etiological pathways of dopamine and serotonin neurotransmission play a central role in heavy alcohol intake and exacerbation in the symptoms of depression. We investigated the role of depression ratings and patterns of heavy drinking on the treatment efficacy of Quetiapine fumarate XR in lowering alcohol intake in alcohol use disorder (AUD) patients. Methods: One hundred and eight male and female heavy drinking AUD patients in the age range of 18 to 64 yrs. received 12 weeks of active treatment. Participants were grouped by the severity grading of depression using Montgomery Asberg Depression Rating Scale (MADRS) (clinically relevant≥8 [CR], clinically non-relevant≤7 [CNR]) at baseline. Drinking history and depression ratings were assessed at the patients visits. Results: Heavy drinking days (HDD) and total drinks (TD) were significantly fewer in CR patients at the treatment end. A true positive response in AUROC analysis supported the lowering of TD in CR patients. The number of drinking days (NDD) and average drinks per drinking day (AvgD) were lower in the CNR patients at treatment-end. Significant associations with increasing effect sizes were observed for all the heavy drinking measures (HDD, TD, NDD and AvgD) and MADRS scores by the end of the treatment course. Conclusions: Baseline elevated depressive symptoms could likely predict the course of heavy alcohol drinking during the treatment, and efficacy outcome of a treatment. AUD patients with baseline clinically significant depression had a progressive lowering in heavy drinking markers significantly corresponding to the lowering of depression symptoms by the end of treatment with Quetiapine fumarate XR.

Sociocultural Correlates of Substance Use among Medical Students

1988 ◽  
Vol 18 (2) ◽  
pp. 97-108 ◽  
Author(s):  
Paul David Forney ◽  
Mary Ann Forney ◽  
Paul Fischer ◽  
John W. Richards ◽  
Joseph Scherger ◽  
...  
Keyword(s):  
Medical Students ◽  
Alcohol Use ◽  
Drug Use ◽  
Tobacco Use ◽  
Sensation Seeking ◽  
Heavy Drinking ◽  
Religious Attendance ◽  
Strongly Correlated ◽  
Drinking Patterns ◽  
Regional Medical

Medical students at four regional medical schools were administered a questionnaire regarding drug, alcohol, and tobacco use, and involvement in sensation-seeking sports and activities. Results of the study indicated that tobacco use was minimal, drug use was moderately low, and alcohol use was extensive. Increased alcohol use was strongly correlated with heavy drinking patterns in parents and male students while decreased drinking was strongly correlated with frequent religious attendance patterns. Students actively using drugs were more likely to have heavy drinking parents and to attend church infrequently. Protestant students and black students were least likely to be involved in drug use. Drug, alcohol, and tobacco use were significantly correlated. Those who use drugs tend to be heavy drinkers and smokers. Preventive education programs can utilize the results in medical school to inform students of potential problem areas based on sociodemographic influences.

Dyadic alcohol use, alcohol-specific conflict, and relationship dissatisfaction in treatment-seeking men and their female partners

2016 ◽  
Vol 34 (8) ◽  
pp. 1206-1226 ◽  
Author(s):  
Richard E. Mattson ◽  
Ashton M. Lofgreen ◽  
Timothy J. O’Farrell
Keyword(s):  
Alcohol Use ◽  
Relationship Satisfaction ◽  
Alcohol Intoxication ◽  
Treatment Seeking ◽  
Drinking Patterns ◽  
Female Partners ◽  
Mediating Role ◽  
Use Patterns ◽  
Relationship Outcomes

Intimate partners consuming different amounts of alcohol tend to have lower relationship satisfaction, whereas those drinking at similar levels often report happier unions. It is presently unclear how dyadic alcohol use patterns impact relationship satisfaction for couples wherein one member has an alcohol use disorder. We examined this using longitudinal data from an alcoholic treatment sample ( N = 181) and further explored whether conflict pursuant to differential use played a mediating role. Partners similar in their baseline frequency of alcohol intoxication reported higher initial satisfaction but experienced significant declines in satisfaction longitudinally. Highly differential alcohol use was associated with lower satisfaction for both partners at baseline, which was mediated by conflict specific to men’s alcohol use. Notably, baseline relationship variables also predicted subsequent changes in alcohol use. These findings overall support a dyadic understanding of alcoholism and highlight that drinking patterns may link to long-term relationship outcomes differently for alcoholics.

scholarly journals Transitions in alcohol use over time: a survival analysis

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Laura B. Koenig ◽  
Jon Randolph Haber ◽  
Theodore Jacob
Keyword(s):  
Alcohol Use ◽  
Alcohol Dependence ◽  
Protective Factors ◽  
Heavy Drinking ◽  
Past Research ◽  
Risk And Protective Factors ◽  
Externalizing Disorders ◽  
Drinking Patterns ◽  
Drinking History ◽  
History Of

Abstract Background The current study examined the predictors of the onset of alcohol use as well as predictors of remission and relapse, both from heavy drinking and from alcohol dependence. Similarities and differences in both clinical and psychosocial predictors across the transitions were examined. Methods A sample of men from the Vietnam Era Twin Registry (N = 1769) completed an assessment of lifetime drinking history, which allowed age markers for starting and stopping different drinking patterns. The men also completed various assessments regarding personality, alcohol motives, and psychiatric diagnoses. Survival analyses were used to examine the predictors of the three transitions of onset, remission, and relapse for the phenotypes of heavy drinking and of alcohol dependence, censoring the individuals who had not yet experienced an event. Results As expected, predictors of onset for drinking, heavy drinking, and alcohol dependence were largely consistent and included externalizing symptomology, nicotine dependence, and cotwin history of drinking as risk factors. Predictors of remission from heavy drinking, somewhat similarly to remission from alcohol dependence, included the risk factor of externalizing disorders but also, as predicted, included more risk and protective factors in the psychosocial realm that were not predictors of onset. Contrary to our prediction, relapse to heavy drinking and alcohol dependence were predicted largely by unique psychosocial risk and protective factors including social and coping motives. Conclusion Current findings extend the findings of past research to remission and relapse in the later decades of life and have implications for treatment of alcohol use problems.

scholarly journals Interaction of Heavy Drinking Patterns and Depression Severity Predicts Efficacy of Quetiapine Fumarate XR in Lowering Alcohol Intake in Alcohol Use Disorder Patients

2020 ◽  
Vol 14 ◽  
pp. 117822182095518
Author(s):  
Vatsalya Vatsalya ◽  
Maiying Kong ◽  
Luis M Marsano ◽  
Zimple Kurlawala ◽  
Kan V Chandras ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Alcohol Intake ◽  
Rating Scale ◽  
Heavy Drinking ◽  
Depression Symptoms ◽  
Drinking Patterns ◽  
Quetiapine Fumarate ◽  
Heavy Alcohol ◽  
Depression Ratings

Background: Shared etiological pathways of dopamine and serotonin neurotransmission play a central role in heavy alcohol intake and exacerbation in the symptoms of depression. We investigated the treatment efficacy of Quetiapine fumarate extended release (XR) in lowering alcohol intake in alcohol use disorder (AUD) patients indicated by the shared alleviation of depression ratings and patterns of heavy drinking. Methods: Hundred and eight male and female heavy drinking AUD patients in the age range of 18 to 64 years. participated in a randomized clinical trial (RCT) to receive 12 weeks of quetiapine XR or placebo (N = 115). Participants were sub-grouped by the severity grading of depression using Montgomery-Asberg Depression Rating Scale (MADRS) (clinically relevant ⩾8 [CR], clinically non-relevant ⩽7 [CNR]) at baseline in both the groups. Drinking history and depression ratings were assessed at the patients’ visits. Results: Heavy drinking days (HDD) and total drinks (TD) were significantly fewer in CR patients at the treatment end. A true positive response in AUROC analysis supported the lowering of TD in CR patients. The number of drinking days (NDD) and average drinks per drinking day (AvgD) were lower in the CNR patients at treatment-end. Significant associations with increasing effect sizes were observed for all the heavy drinking measures (HDD, TD, NDD, and AvgD) and MADRS scores by the end of the treatment course. Conclusions: Baseline elevated depressive symptoms could likely predict the course of heavy alcohol drinking during the treatment, and efficacy outcome of a treatment. AUD patients with baseline clinically significant depression had a progressive lowering in heavy drinking markers significantly corresponding to the lowering of depression symptoms by the end of treatment with Quetiapine fumarate XR. ClinicalTrials.gov: NCT#0049862 ( https://clinicaltrials.gov/ct2/show/NCT00498628?term=litten&draw=2&rank=3 )

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