scholarly journals Dietary Salt-Related Knowledge, Attitude, Behaviors, and Hypertension in a Rural Northern Thailand Population

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 870-870
Author(s):  
Celina Morales ◽  
Pimbucha Rusmevichientong
Keyword(s):  
Blood Pressure ◽  
Logistic Regression ◽  
Family History ◽  
Regression Model ◽  
Logistic Regression Model ◽  
Salt Intake ◽  
Dietary Salt ◽  
Chiang Mai ◽  
Attitudes And Behaviors ◽  
History Of

Abstract Objectives The objectives of this study were to examine the dietary salt-related knowledge, attitudes, and behaviors associated with the prevalence of hypertension among adults residing in rural Northern Thailand. Methods A cross-sectional study utilizing convenience sampling was administered in San Pa Tong District, Chiang Mai, Thailand. The one-on-one interview was conducted to assess subject's knowledge, attitudes, and behaviors relating to their dietary salt intake. Various food frequencies for foods high in salt were also measured. Each subject's blood pressure was measured twice before and after the interview. A logistic regression model was used in the analysis to determine potential hypertension risk factors. Results A total of 403 adults participated in the study. A majority of participants were female (73.2%), and the average age was 62.5 years old. Half of participants reported a family history of hypertension and 32% of participants were hypertensive. The major results from the logistic regression model indicated positive attitudes towards decreasing salt intake lead to a lower chance of becoming hypertensive (OR = 0.934). However, a family history of high blood pressure (OR = 1.417), a higher knowledge score about foods high in salt (OR = 1.254), daily use of Monosodium Glutamate (MSG) in food preparation (OR = 1.959) and buying outside food to eat at home (OR = 5.692) lead to a higher chance of becoming hypertensive. Conclusions Our findings suggest higher knowledge does not decrease the chance of becoming hypertensive. However, there is a positive association between hypertension and dietary salt-related behaviors among adults living in rural Thai communities. More specifically, salt-reduction interventions should focus on promoting home-cooked meal preparation with lower salt substitutes to MSG. Funding Sources NIMHD Minority Health and Health Disparities Research Training Program (MHRT), California State University, Fullerton (Department of Public Health) and Chiang Mai University (Department of Community Medicine).

Blood Pressure and Intra-Erythrocyte Sodium during Normal and High Salt Intake in Middle-Aged Men: Relationship to Family History of Hypertension, and Neurogenic and Hormonal Variables

1984 ◽  
Vol 66 (4) ◽  
pp. 427-433 ◽  
Author(s):  
Ottar Gudmundsson ◽  
Hans Herlitz ◽  
Olof Jonsson ◽  
Thomas Hedner ◽  
Ove Andersson ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Family History ◽  
Salt Intake ◽  
Sodium Intake ◽  
Positive Family History ◽  
Sodium Content ◽  
High Salt Intake ◽  
History Of ◽  
Family History Of Hypertension ◽  
Erythrocyte Sodium

1. During 4 weeks 37 normotensive 50-year-old men identified by screening in a random population sample were given 12 g of NaCl daily, in addition to their usual dietary sodium intake. Blood pressure, heart rate, weight, urinary excretion of sodium, potassium and catecholamines, plasma aldosterone and noradrenaline and intra-erythrocyte sodium content were determined on normal and increased salt intake. The subjects were divided into those with a positive family history of hypertension (n = 11) and those without such a history (n = 26). 2. Systolic blood pressure and weight increased significantly irrespective of a positive family history of hypertension. 3. On normal salt intake intra-erythrocyte sodium content was significantly higher in those with a positive family history of hypertension. During high salt intake intra-erythrocyte sodium content decreased significantly in that group and the difference between the hereditary subgroups was no longer significant. 4. In the whole group urinary excretion of noradrenaline, adrenaline and dopamine increased whereas plasma aldosterone decreased during the increased salt intake. 5. Thus, in contrast to some earlier studies performed in young subjects, our results indicate that moderately increased sodium intake acts as a pressor agent in normotensive middle-aged men whether there was a positive family history of hypertension or not. We confirm that men with positive family history of hypertension have an increased intra-erythrocyte sodium content, and that an increase in salt intake seems to increase overall sympathetic activity.

scholarly journals Association between Attention Deficit Hyperactivity Disorder and Suicide Attempts in Patients with Bipolar Disorder

2019 ◽  
Author(s):  
Jafar Fili ◽  
Marzieh Nojomi ◽  
Katayoon Razjouyan ◽  
Mojgan Kahdemi ◽  
Rozita Davari- Ashtiani
Keyword(s):  
Bipolar Disorder ◽  
Logistic Regression ◽  
Regression Model ◽  
Logistic Regression Model ◽  
Suicide Attempts ◽  
P Value ◽  
Hyperactivity Disorder ◽  
Significant Difference ◽  
Chi Squared ◽  
History Of

Objective: The present study aimed to examine the association between ADHD and suicide attempts among adolescents with bipolar disorder. Method: Participants were 168 adolescents who fulfilled DSM-IV-TR criteria for bipolar disorder. They were divided into 2 groups: The first group of patients with bipolar disorder with a history of suicide attempts (n = 84) and the second group without a history of suicide attempts (n = 84). ADHD and other variables were analyzed using a chi-squared test and logistic regression model. Results: No significant difference was observed between the 2 groups in comorbidity of ADHD and other psychiatric disorders (P value > 0/05). In the logistic regression model, and after controlling for other factors, gender (OR = 3.9, CI 95%: 1.5-9.6) and history of sexual abuse (OR = 3.4; CI 95%: 1.06-11.3) were the only 2 factors associated with a history of suicide attempts. Conclusion: No significant association was found between ADHD and suicide attempts in adolescents with bipolar disorder.

scholarly journals Persistent organic pollutants distribution in plasma lipoprotein fractions

2023 ◽  
Vol 83 ◽  
Author(s):  
S. Khwaja ◽  
S. I. Hussain ◽  
M. Zahid ◽  
Z. Aziz ◽  
A. Akram ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Logistic Regression ◽  
Regression Model ◽  
Lipid Profile ◽  
Organic Pollutants ◽  
Persistent Organic Pollutants ◽  
Logistic Regression Model ◽  
Serum Samples ◽  
Binary Logistic Regression Model

Abstract This study determines the associations among serum lipid profiles, risk of cardiovascular disease, and persistent organic pollutants. Using Gas chromatography technique, the intensity of toxic pollutant residues in serum samples of Hypertensive patients were measured. Based on statistical analysis, the effects of different covariates namely pesticides, age, systolic blood pressure, diastolic blood pressure, and lipid profile duration was checked using the logistic regression model. Statistical computation was performed on SPSS 22.0. The P-values of F-Statistic for each lipid profile class are greater than 0.01 (1%), therefore we cannot reject the null hypothesis for all cases. The estimated coefficients, their standard errors, Wald Statistic, and odds ratio of the binary logistic regression model for different lipid profile parameters indicate if pesticides increase then the logit value of different lipid profile parameters changes from -0.46 to -0.246 except LDL which increases by 0.135. The study reports a significantly increased threat of cardiovascular disease with increased concentrations of toxic pollutants.

Blood pressure control in individuals with hypertension who used a digital, personalized nutrition platform (Preprint)

2021 ◽  
Author(s):  
Shivani Bakre ◽  
Benjamin Shea ◽  
Jason Langheier ◽  
Emily A Hu
Keyword(s):  
Blood Pressure ◽  
Logistic Regression ◽  
Systolic Blood Pressure ◽  
Regression Model ◽  
Diastolic Blood Pressure ◽  
Logistic Regression Model ◽  
New Technologies ◽  
Strong Association ◽  
Absolute Reduction ◽  
Stage 1

BACKGROUND While there is a strong association between adhering to a healthy dietary pattern and reductions in blood pressure, adherence still remains low. New technologies aimed to help facilitate behavior change may have an effect on reducing blood pressure among individuals with hypertension. OBJECTIVE To evaluate characteristics of participants with stage 2 hypertension who used Foodsmart and to assess changes in systolic blood pressure (SBP) and diastolic blood pressure (DBP). METHODS We analyzed demographic, dietary, and clinical characteristics collected from 11,934 adults with at least two blood pressure readings who used the Foodsmart platform. Stage 2 hypertension was defined as SBP ≥ 140 mmHg or DBP ≥ 90 mmHg. We calculated mean changes in blood pressure among participants with stage 2 hypertension and stratified by length of follow-up and the covariates associated with achieving blood pressure levels below stage 2 hypertension. We compared changes in diet quality and weight between participants with stage 2 hypertension at baseline who achieved stage 1 hypertension or below and those who did not. RESULTS We found that 47.2% (5,627/11,934) and 10.6% (1,269/11,934) of the participants with at least two SBP and DBP readings had stage 1 and stage 2 hypertension, respectively, at baseline. Among Foodsmart participants with stage 2 hypertension at baseline, SBP and DBP had an absolute reduction, on average, of 5.6 mmHg and 4.0 mmHg, respectively. 33.0% (419/1,269) of participants with stage 2 hypertension at baseline achieved blood pressure levels below stage 2 hypertension (SBP < 140 mmHg and DBP < 90 mmHg). Using a multivariable ordinal logistic regression model, changes in Nutriscore and weight were statistically significantly associated with changes in blood pressure levels for users with stage 2 hypertension at baseline. Using a multivariable logistic regression model, we found that baseline Nutriscore, change in Nutriscore, and change in weight were all associated with the likelihood of users with stage 2 hypertension at baseline to achieve a lower blood pressure category. Among Foodsmart participants with stage 2 hypertension at baseline, systolic blood pressure and diastolic blood pressure had an absolute reduction, on average, of 5.6 mm Hg and 4.0 mm Hg, respectively. 33.0% (419/1,269) of participants with stage 2 hypertension at baseline achieved blood pressure levels of stage 1 hypertension (systolic blood pressure < 140 mm Hg and diastolic blood pressure < 90 mm Hg) in their last blood pressure entry. CONCLUSIONS This study evaluated changes in SBP and DBP among users of the Foodsmart platform with hypertension and found that users with stage 2 hypertension, on average, improved their blood pressure levels over time.

Hypertension and nutrition in the young: early intervention?

1986 ◽  
Vol 64 (6) ◽  
pp. 849-851 ◽  
Author(s):  
W. H. Weidman
Keyword(s):  
Blood Pressure ◽  
Body Size ◽  
Early Intervention ◽  
Family History ◽  
Children And Adolescents ◽  
Salt Intake ◽  
Sodium Intake ◽  
Primary Hypertension ◽  
Dietary Sodium ◽  
History Of

The few studies, carried out on infants, children, and adolescents, relating blood pressure to sodium intake have shown a weak positive correlation in some but not all individuals. The effect of body size on blood pressure confounds the interpretation of the effect of dietary sodium on blood pressure. There appear to be sodium-sensitive and sodium-unsensitive infants, children, and adolescents and is probably genetically transmitted. Most infants, children, and adolescents in industrialized populations have a salt intake far greater than required, and reduction in dietary sodium is safe and may be beneficial to those individuals with a family history of primary hypertension.

scholarly journals Histological chorioamnionitis is associated with an increased risk of wheezing in preterm children less than 34 gestational weeks

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiaoli Wang ◽  
Haiyuan Li ◽  
Qianqian Zhang ◽  
Qianwen Shen ◽  
Dan Zhu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Logistic Regression ◽  
Regression Model ◽  
Logistic Regression Model ◽  
Multivariate Logistic Regression Model ◽  
Atopic Diseases ◽  
Multivariate Logistic Regression ◽  
Preterm Children ◽  
Increased Risk ◽  
Anthropometric Indexes

Abstract Background Chorioamnionitis is associated with various neonatal short- and long-term morbidities. The effect of chorioamnionitis on premature children’s outcomes remains controversial. The aim of this study is to investigate the relationship between histological chorioamnionitis (HCA) and physiological development, wheezing, and atopic diseases in preterm children. Methods Singleton, preterm children (< 34 weeks), whose mother underwent pathological placental examinations, were retrospectively enrolled and the outcomes were assessed at 24–40 months during follow-up. Wheezing and atopic diseases including eczema, food allergies, and allergic rhinitis were screened by a questionnaire along with medical diagnosis. Anthropometric indexes and blood pressure were measured. Cognitive and behavioural developments were assessed by the Gesell Development and Diagnosis Scale. Blood IgE and routine examination were analyzed with venous blood and serum metabolomic profiling was assessed via liquid chromatography-mass spectrometry (LC-MS). A multivariate logistic regression model was used to estimate the association between HCA and the current outcomes. Results Among the 115 enrolled children, 47 were exposed to HCA. The incidence of wheezing was significantly higher in children exposed to HCA, as 38.30% of children who were exposed to HCA and 16.18% of children who were not had been diagnosed with wheezing. After adjusting for related confounders in the multivariate logistic regression model, there remained a 2.72-fold increased risk of wheezing in children with HCA (adjusted odds ratio, aOR, 2.72; 95% confidence interval, 1.02–7.23). Moreover, 163 differential metabolites, such as butanoic acid, annotemoyin 1 and charine, were identified in the HCA exposed children’s serum. Enrichment analysis revealed that these compounds participated in diverse key metabolomic pathways relating to physical and neuro- developments, including glycerophospholipid, alpha-linolenic acid and choline metabolisms. There were no significant differences in atopic diseases, serum IgE, eosinophils’ level, anthropometric indexes, blood pressure, or cognitive or behavioural developments between the two groups. Conclusion HCA exposure is associated with an increased risk of wheezing in preterm children less than 34 gestational weeks.

scholarly journals Determinants that Associated with Traveling History of COVID-19 Patients in Ethiopia During Stay at Home State of Emergency

2021 ◽  
Author(s):  
Kindu Kebede Gebre ◽  
Million Wesenu Demissie
Keyword(s):  
Logistic Regression ◽  
Regression Model ◽  
Logistic Regression Model ◽  
Demographic Factors ◽  
Age Group ◽  
State Of Emergency ◽  
Corona Virus ◽  
Gender And Age ◽  
History Of ◽  
Socio Demographic Factors

Abstract Background: The recent outbreak of Novel Coronavirus (SARS-CoV-2) Disease (COVID-19) has put the world on alert and impacting societies around the world in an unprecedented manner. The main aims of this study was to investigate the association among the socio-demographic factors with traveling history of COVID-19 Patients in Ethiopia during stay at home state of emergency. Methods: A total of 162 respondents with COVID-19 during March 13, 2020 to May 6, 2020 in Ethiopia were used. Two sided chi-square test was used to test the association between the socio demographic factors among COVID-19 Patients. A log-complement logistic regression model was used to compute the health ratios (HR) and 95% confidence interval (CI) to measure the effect of those factors. Results: The data was analyzed using 162 patients of severe acute respiratory syndrome corona virus-2. An association was found between traveling history of COVID-19 infected patients and Gender (male vs female) [B =5.410, p<0.020] and Age group [a=13.082, p<0.004]. Log-complement logistic regression model showed that Gender and Age were significant factors associated to traveling history of COVID-19 Patients. Health ratio showed that increasing risk of traveling history for COVID-19 patients associated with higher number of males [ HR=0.5895, 95%CI: 0.4007-0.8672, P<0.0073] and Age group 18-39 years [HR=0.4139, 95%CI: 0.2385-0.7184, P<0.0017] on patients of COVID-19. Akaike information criteria with minimum value [AIC=1.2158] indicated that Log complement logistic regression model was fitted the data well for the similar dataset of patients’ with novel corona virus. Conclusions: Male Gender and Age group 18-39 years are significant socio-demographic factors associated to traveling history of patients with corona virus disease. Further socio-demographic investigations are required to better understand the extent of association with Gender and Age for effective intervention and fight this pandemic to preserve lives.

scholarly journals Prolylcarboxypeptidase Is a Risk Factor for Cardiovascular Events

Blood ◽  
2014 ◽  
Vol 124 (21) ◽  
pp. 1531-1531
Author(s):  
Alvin H. Schmaier ◽  
Alona Merkulova ◽  
Haley Gittleman ◽  
Omar Alhalabi ◽  
Evi Stavrou ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Risk Factor ◽  
Regression Model ◽  
Allele Frequency ◽  
Coronary Disease ◽  
Ace Inhibitors ◽  
Odds Ratio ◽  
Logistic Regression Model ◽  
Conflicts Of Interest ◽  
History Of

Abstract BACKGROUND: Prolylcarboxypeptidase (PRCP) is a membrane-associated serine protease that regulates biologic peptides bradykinin, angiotensin II, α-melanocyte stimulating hormone, and activates prekallikein. PRCP and its variants have been associated with metabolic syndrome in males, hypertension in preeclampsia, resistance to ACE inhibitors, and embryonic angiogenesis. Recent studies on PRCPgt/gt mice that have 25% normal PRCP levels show that these animals are hypertensive, have higher risk for arterial thrombosis, increased vascular inflammation, and reduced angiogenic repair after ischemia and injury (Blood 117:3929, 2011; Blood 122:1522, 2013). The hypothesis of this investigation is that polymorphisms in PRCP are associated with cardiovascular disease (CVD). METHODS: DNA from 2,243 subjects from the PEACE Trial (NEJM 351:2058, 2004) were genotyped at 2 PRCP SNPs (rs7104980, rs2298668) and 3 KLKB1 (prekallikrein) SNPs (rs4253252, rs3733402, rs3087505). These subjects were 82% female and had a history of (in decreasing frequency) angina (71%), angiographic coronary disease (66%), heart attack (58%), PTCA (44%), hypertension (42%), CABG (36%), diabetes (15%), stroke (4%), and TIA (3%). The association between single SNP alleles and different cardiovascular related phenotypes was assessed using logistic regression models. These models were adjusted for age, weight, gender, history of hypertension, and history of diabetes. RESULTS: When the logistic regression model was adjusted for age, weight, and gender, SNP rs710980 in PRCP had a 21% increased odds [odds ratio=1.211; 95% CI=(1.008, 1.454)] of having a history of PTCA if carrying the G allele (frequency of 66%) as compared to not having the G allele (frequency 34%). Additionally, adjusting the logistic regression model for history of hypertension and diabetes did not alter the odds ratio for PTCA history. However when the logistic regression model included history of hypertension and diabetes, the odds of having a history of a MI if carrying the same allele also is increased by 21% [odds ratio=1.21; 95% CI=(1.001, 1.455)]. In summary, the rs710980 intronic PRCP SNP conferred risk for CVD, while the PRCP exonic SNP rs2298668 showed no relationship in this population. Alternatively, the exonic KLKB1 SNP rs3733402 of Apple Domain 2 where high molecular weight kininogen binds conferred reduced odds of 24% [odds ratio=0.76; 95% CI=(0.622, 0.928)] of having a history of angiographic coronary disease if carrying the G allele (frequency 67%) as compared to not having the G allele (frequency of 33%). The other two KLKB1 SNPs showed no associations. DISCUSSION: These combined data on PRCP suggest that it is a risk factor for CVD. The present genetic data are consistent with biochemical, cell culture, and in vivo investigations showing that PRCP levels influence vascular biology, renal function, and metabolism. The extent of the genetic associations of PRCP polymorphisms with CVD may be resultant of the database interrogated. The PEACE trial consisted of individuals not severely ill with CVD. Its hypothesis to show that administration of ACE inhibitors leads to increased protection from mild CVD was not met. However, the present investigation showing several positive odds ratios with a certain PRCP SNP for CVD suggests that PRCP is a stronger risk factor for CVD than can be demonstrated in the PEACE subject population. PRCP should be interrogated in additional populations of subjects with CVD. Funding Support: NIH HL052779-17, HL112666-2 Disclosures No relevant conflicts of interest to declare.

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