scholarly journals Association Between Intake of Antioxidant Vitamins and Metabolic Syndrome Prevalence Among Korean Adults (P24-001-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Seoeun Ahn ◽  
Shinyoung Jun ◽  
Jiae Shin ◽  
Dongwoo Ham ◽  
Eunhee Choi ◽  
...  

Abstract Objectives The purpose of this study was to examine the association between intake of antioxidant vitamins and prevalence of metabolic syndrome among Korean adults. Methods Based on the data from the 2013∼2016 Korea National Health and Nutrition Examination Survey (KNHANES), a total of 10,351 adults aged 19∼64 years were included. Presence of metabolic syndrome was determined using the National Cholesterol Education Program Adult Treatment Panel Ⅲ criteria. Intakes of antioxidant vitamins (vitamin A, vitamin C, and vitamin E) were estimated by combining a 24-h dietary recall data with an antioxidant vitamin database for common Korean foods. We analyzed through the multiple logistic regression method to assess the association between dietary antioxidant vitamins and metabolic syndrome. Results Men in the highest tertile of vitamin C (OR = 0.75, 95% CI = 0.58–0.95, p for trend = 0.0212) and vitamin E (OR = 0.76, 95% CI = 0.60–0.96, p for trend = 0.0212) intakes showed a significantly lower prevalence of metabolic syndrome than those in the lowest tertiles. Women in the highest intake group of vitamin A had a lower OR for increased waist circumference (OR = 0.80, 95% CI = 0.66–0.99, p for trend = 0.0618) than the lowest intake group. The OR for elevated triglycerides was lower among women in the highest tertile of vitamin C compared with those in the lowest tertile (OR = 0.75, 95% CI = 0.61–0.93, p for trend = 0.0016). Conclusions These results suggest that the dietary intake of antioxidant vitamins might be associated with the prevalence of metabolic syndrome among Korean adults. Further prospective research is required to elucidate the association between dietary antioxidants intake and the incidence of metabolic syndrome and other chronic diseases. Funding Sources This research was supported by Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Science and ICT(NRF-2018R1A2B6007070). Supporting Tables, Images and/or Graphs

2020 ◽  
Vol 8 ◽  
pp. 205031212094053
Author(s):  
Md. Mustafa Kamal ◽  
Farina Aziz ◽  
Md. Rabiul Islam ◽  
Monira Ahsan ◽  
Sheikh Nazrul Islam

Introduction: Acute respiratory infection is a major cause of death for under-5 children in Bangladesh. We aimed to analyze the effect of immunonutritional status, healthcare factors, and lifestyle on the incidence of acute respiratory infection among under-5 children taking individual-level and contextual-level risk factors into consideration. Methods: This study recruited 200 children suffering from acute respiratory infection and 100 healthy controls matched by age, sex, and sociodemographic profile. Serum antioxidant vitamin A (retinol), vitamin C (ascorbic acid), and vitamin E (α-tocopherol) were assessed along with the impact of vaccination, socioeconomic factors, and Z-score on the incidence of acute respiratory infection. Results: Serum antioxidant vitamins were significantly lower in the acute respiratory infection children compared to the non–acute respiratory infection group. Vitamin A was found to be significantly high in acute respiratory infection children who were breastfed for more than 1 year. Vitamin E levels were found to be significantly higher in the acute respiratory infection children who were immunized. Compared to the children living in tin-shed house or huts, serum vitamin E level increased in those acute respiratory infection children who resided in apartments. Vitamin A level was significantly high in those acute respiratory infection children whose height-for-age was −2 SD and above ( Z-score), and vitamin C levels were also significantly high in those acute respiratory infection children whose weight-for-height was −2 SD and below ( Z-score). Conclusion: Deficiencies of antioxidant vitamins along with healthcare and lifestyle factors have a significant influence on the incidence of acute respiratory infection among under-5 children in Bangladesh.


2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Eunhee Choi ◽  
Seoeun Ahn ◽  
Kyungho Ha ◽  
Hyojee Joung

Abstract Objectives Several epidemiological studies have examined the association between fish and dietary fish oil intake and metabolic syndrome in a population. However, few studies have investigated fish and dietary fish oil intake and its association with the risk of metabolic syndrome in the Korean population. Methods Using data from the 2013–2016 Korea National Health and Nutrition Examination Survey, a total of 14,519 adults (6,135 men and 8,384 women) aged ≥ 19 years were involved in this study. Dietary intakes of fish and fish oil including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) were estimated by a 24-h dietary recall. Metabolic syndrome was diagnosed using the National Cholesterol Education Program Adult Treatment Panel III criteria. The odds ratios (ORs) for the presence of metabolic syndrome according to the tertile of fish and fish oil intakes were calculated using a multiple logistic regression model. Results The prevalence of metabolic syndrome among the participants was 9.18%. The mean intake (standard error, SE) of fish, EPA and DHA was 123.35 (2.67) g/day, 103.43 (2.48) mg/day and 179.21 (4.75) mg/day for the study participants, respectively. Dietary intakes of fish and fish oil were not associated with the prevalence of metabolic syndrome, however, they were associated with the prevalence of several metabolic abnormalities. Men in the highest tertile of energy adjusted DHA intake from fish showed a 20% decreased risk of hypertriglyceridemia (OR, 0.80; 95% CI, 0.67–0.96, p for trend, 0.0274), compared with those in the lowest tertile. However, Women in the highest tertile of fish intake showed a higher prevalence of impaired fasting glucose (OR, 1.70; 95% CI, 1.24–2.33) than those in the lowest tertile. Conclusions Our findings suggest that a higher intake of dietary fish oil might be associated with a lower risk of hypertriglyceridemia in Korean men. Thus, further prospective studies are needed to examine the association of fish and fish oil with metabolic syndrome. Funding Sources This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (NRF-2018R1A2B6007070) and the National Institute of Fisheries Science (R2019051).


2013 ◽  
Vol 13 (1) ◽  
pp. 30-35
Author(s):  
Indranil Dawn ◽  
Susmita Sarkar ◽  
Chinmoy De

Osteoarthritis (OA) is a strongly age-related joint disorder that is defined as a gradual loss of articular cartilage. Current concepts of the pathogenic mechanisms of OA suggest that there isa shift in the homeostatic balance between the destruction and synthesis of bone and cartilage,with a net progressive destruction of these tissues. Recent studies of the biology of chondrocytes show that these cells actively produce reactive oxygen species (ROS). ROS are capable of inducing apoptotic cell death in chondrocytes, but more important, they can result in the degradation of aggrecan and collagen. Micronutrient antioxidants such as alpha- Tocopherol (Vitamin E) and Vitamin C also act to reduce the effects of ROS. A hospital based case control study was conducted in Burdwan Medical College, West Bengal, India on 76 postmenopausal women aged 45–70 years suffering from Osteoarthritis (OA) of the knee joint, which was diagnosed from symptoms, clinical examinations and radiographic findings. The 151 controls were selected from the healthy persons .plasma vitamin C and serum vitamin E ware measured.. Knee joint radiographs were evaluated with the Kellgren–Lawrence grading scale .Furthermore both were correlated with Kellgren–Lawrence grading scale to find out possible association between the antioxidant vitamins and the disease progression. Results showed that there was a significant decrease in antioxidant vitamin levels in patients with knee joint osteoarthritis as compared to the controls suggests that treatment with antioxidants in the initial stages of the disease may be useful as secondary therapy. Both antioxidant vitamins showed negative correlation with Kellgren–Lawrence grading. Both vitamins decreased with increasing Kellgren–Lawrence grade. So antioxidant vitamin can be use to assess the disease severity. DOI: http://dx.doi.org/10.3329/bjms.v13i1.14046 Bangladesh Journal of Medical Science Vol. 13 No. 01 January2014: 30-35


2018 ◽  
Vol 58 (10) ◽  
pp. 1829
Author(s):  
M. Mohiti-Asli ◽  
M. Ghanaatparast-Rashti

This study investigated the effect of feeding vitamin E, vitamin C, and two sources of vegetable oil on immune response and meat quality of broilers. A total of 320 one-day-old chicks were used in a completely randomised design with eight treatments arranged as a 2 × 2 × 2 factorial with two levels of vitamin E (0 and 200 mg/kg), two levels of vitamin C (0 and 1000 mg/kg), and two sources of vegetable oil (soybean and canola). Dietary supplementation of either vitamin E or C increased (P < 0.05) secondary humoral response, whereas oil sources had no significant effect. Broilers fed soybean oil had lower cellular response to the phytohemagglutinin skin test than those fed canola oil in diet, and supplementation of vitamin E increased cellular immune response. However, fat, cholesterol and pH of meat were not affected by source of oil or antioxidants, lipid oxidation was higher (P < 0.05) in thigh and breast meat of broilers fed soybean oil than canola oil. Dietary supplementation of vitamin E decreased (P < 0.05) lipid oxidation in thigh and breast of broilers fed diet containing soybean oil, without any effect on meat oxidation of those fed canola oil. Dietary supplementation of vitamin C increased lipid oxidation in thigh meat of broilers (P < 0.05). It can be concluded that inclusion of soybean oil to the diet, compared with canola oil, increased need for antioxidant. Vitamin E had beneficial effects on immune response and reduced meat lipid oxidation; nonetheless future studies should explore the antioxidant effect of vitamin C in stored meat.


2020 ◽  
Vol 12 (1) ◽  
pp. 166-172
Author(s):  
Anna Pietrzak ◽  
Anna Kęska ◽  
Marziyeh Saghebjoo ◽  
Zeynab Nezamdoost

SummaryStudy aim: The purpose of this study was to compare intake of antioxidant vitamins (A, C, E) in young women with various levels of physical activity.Material and methods: The study included 3 groups of females: 40 women with no extra physical activity (Sedentary), 40 women involved in regular, moderate sports activities (Recreationally Active) and 40 female athletes competing at an international level (Athletes). Participants’ diet was assessed on the basis of 3-day diet records which were analysed using the computer program ‘Dieta 5.0’. Body composition was evaluated by the bioelectrical impedance analysis (BIA) method.Results: Athletes were characterized by the lowest body fat and highest lean body mass in comparison with the other groups. They also showed the highest intake of energy, proteins and carbohydrates compared to Active and Sedentary women. The consumption of vitamin A amounted to 180.0% of RDA in Athletes, 98.8% in Recreationally Active and 97.8% in Sedentary women. Vitamin C intake in Athletes equalled 275.0% of RDA, whereas the deficiency of this vitamin was observed in Recreationally Active and Sedentary women (62.3% and 46.1% of RDA, respectively). The study groups showed consumption of vitamin E at the level of 146.7% of AI in Athletes, 115.0% in Recreationally Active and 111.3% in Sedentary women.Conclusion: Athletes consumed excessive amounts of antioxidant vitamins. Recreationally Active and Sedentary women met the demand for vitamin A and E, but the intake of vitamin C was not sufficient, which could lead to health problems. The current findings also indicate that energy intake was at a low level regardless of the study group.


1998 ◽  
Vol 22 (1) ◽  
pp. 58-64 ◽  
Author(s):  
Jussara Personelle ◽  
Ewaldo Bolivar de Souza Pinto ◽  
Rog&#x000E9;rio Oliveira Ruiz

2019 ◽  
Vol 149 (9) ◽  
pp. 1667-1673 ◽  
Author(s):  
Hanqi Luo ◽  
Kevin W Dodd ◽  
Charles D Arnold ◽  
Reina Engle-Stone

ABSTRACT Background To estimate usual intake distributions of dietary components, collection of nonconsecutive repeated 24-h dietary recalls is recommended, but resource limitations sometimes restrict data collection to single-day dietary data per person. Objectives We developed a new statistical method, the NCI 1-d method, which uses single-day dietary data and an external within-person to between-person variance ratio to estimate population distributions of usual intake of nearly-daily consumed foods and nutrients. Methods We used NHANES 2011–2014 data for men (n = 4938 and n = 4293 for the first and second 24-h recalls) to compare nutrient intake distributions of vitamin A, magnesium, folate, and vitamin E generated by the 1-d method (with use of only the first recall per person) with those from the NCI amount-only method (with use of all days of dietary intake per person). The within-person to between-person variance ratio from the amount-only model was used as the unbiased “external” estimate for the 1-d method. We also examined the effect of mis-specification of variance ratios on usual intake distributions. Results The amount-only and 1-d methods estimated statistically equivalent median (25p, 75p): 647 (459, 890) compared with 648 (461, 886) µg retinol activity equivalents/d, 338 (268, 420) compared with 334 (266, 417) mg magnesium/d, 595 (458, 762) compared with 589 (456, 758) µg dietary folate equivalents/d, and 9.7 (7.3, 12.6) compared with 9.6 (7.3, 12.7) mg vitamin E/d. As the external variance ratios increased from 25% to 200% of the unbiased ratios, the prevalence of inadequate intake ranged from 53% to 43% for vitamin A, 57% to 55% for magnesium, 16% to 2% for folate, and 70% to 73% for vitamin E. Conclusions The 1-d method is a viable statistical method for estimating usual intakes of nearly-daily consumed dietary components when the variance ratio is unbiased. Results are sensitive to variance ratio selection, so researchers should still collect replicate data where possible.


2014 ◽  
Vol 3 (1) ◽  
pp. 13-19
Author(s):  
Retno Wahyuningsih ◽  
Darmono SS ◽  
Ani Margawati

Background: Infectious disease remains a health problem for the elderly. The elderly are susceptible to infection,because the body's ability to fight infection decreases immunity. The immune status can be improved through the effortsof immunization, and nutrition. However the elderly are not sufficient to meet the nutritional needs of food, so probioticcould support nutritional adequacy.Objective: Analyze the effect of probiotic Lactobacillus helveticus Rosell-52 and Lactobacillus rhamnosus Rosell-11 onlevels of lymphocytes in the elderly in Tresna Elderly Social Institution Puspakarma Mataram, West Nusa Tenggara.Methods: This was quasi-experimental study, randomized pre-post control group design. The population is elderly aged60-75 years, involving 45 subjects were divided randomly into two groups, namely the treatment groups givenprobiotics and the control group was given a placebo. Probiotics were given for 4 weeks, with the provision of onecapsule a day. Immunity status in this study was lymphocytes. Data examined included the intake of nutrients (protein,vitamin A, vitamin C, vitamin E, Fe, Zn), health status, quality of sleep, and levels of lymphocytes in the elderly. Datawere analyzed using bivariate with different test Independent sample t-test, Mann-Whitney U test, Spearman, Pearson,and Paired t-test.Results: Increasing number of lymphocytes were significantly in the treatment group (χ ± SD: 1.84 ± 1.85) and in thecontrol group (0.95 ± 5.0). There is no relationship between intake (protein, vitamin A, vitamin C, vitamin E, Fe, Zink),physical health status, and quality of sleep with levels of lymphocytes.Conclusion: Probiotics in 4 weeks is proven to increase the number of lymphocytes in the elderly.


Author(s):  
Nwokolo Lorreta Nwakaego ◽  
Onyekwelu Kenechukwu Chibuike ◽  
Ene Martin Chukwugekwu ◽  
Adilieje Chioma Marylyn ◽  
Ezechukwu Ifunanya Ngozi ◽  
...  

Objective: This study investigated the in vitro antioxidant and free radical potentials of methanol extracts of Uvaria chamae leaves and roots.Methods: Fresh Uvaria chamae leaves and roots were air dried, pulverized and extracted using methanol. Phytochemical, total phenolic, flavonoids, antioxidant and tannin contents, DPPH, hydroxyl, and superoxide radical scavenging properties of the extracts were determined using standard methods.Results: In vitro antioxidant potentials revealed that methanol extract of Uvaria chamae leaves contains vitamin A (4871±79.21 I. U) and vitamin C (1.72±0.02%) while the root extract contains vitamin A (673.28±0.00I. U) and vitamin C (1.66±0.01%). Both extracts had equal contents of vitamin E (8.83±0.04 mg/100g). The leaf extract scavenged 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) in a concentration dependent manner with the correlation coefficient (R2) of 0.839 and effective concentration (EC50) of 31.19 µg/ml, while the root extract scavenged DPPH with R2 of0.778 and EC50 of 14.00 µg/ml. The leaf and root extracts scavenged superoxide radical and hydroxyl radical with EC50 of 5.93 µg/ml and 719.45 µg/ml; 107.89 µg/ml and 912.01 µg/ml respectively compared to the EC50 of ascorbic standard (30.27 µg/ml) and EC50 of vitamin E standard (106.66µg/ml) respectively. The leaf extract showed significantly higher (p<0.05) anti radical power (ARP) of superoxide (0.17) compared to the root extract (0.0014) and the root extract showed significantly higher (p<0.05) ARP of DPPH (0.071) compared to the leaf extract (0.032).Conclusion: The leaves and roots of Uvaria chamae are rich in natural antioxidants that can be exploited in the treatment of diseases related to oxidative stress.


2006 ◽  
Vol 15 (2) ◽  
pp. 395-397 ◽  
Author(s):  
Stephanie A. Navarro Silvera ◽  
Meera Jain ◽  
Geoffrey R. Howe ◽  
Anthony B. Miller ◽  
Thomas E. Rohan

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